Page last updated: 2024-08-24

aptiganel and Acute Brain Injuries

aptiganel has been researched along with Acute Brain Injuries in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (75.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Butcher, I; Lecky, FE; Lingsma, HF; Lu, J; Maas, AI; McHugh, GS; Murray, GD; Perel, P; Roozenbeek, B; Steyerberg, EW; Weir, J	1
Grosset, DG; Lees, KR; Muir, KW	1
McBurney, RN	1
Kroppenstedt, SN; Schneider, GH; Thomale, UW; Unterberg, AW	1

Reviews

1 review(s) available for aptiganel and Acute Brain Injuries

Article	Year
Development of the NMDA ion-channel blocker, aptiganel hydrochloride, as a neuroprotective agent for acute CNS injury. International review of neurobiology, 1997, Volume: 40 Topics: Acute Disease; Brain Injuries; Cerebrovascular Disorders; Clinical Trials as Topic; Drugs, Investigational; Glasgow Coma Scale; Guanidines; Humans; N-Methylaspartate; Neuroprotective Agents; Reference Values; Spinal Cord Injuries	1997

Article

Year

Development of the NMDA ion-channel blocker, aptiganel hydrochloride, as a neuroprotective agent for acute CNS injury.

International review of neurobiology, 1997, Volume: 40

Topics: Acute Disease; Brain Injuries; Cerebrovascular Disorders; Clinical Trials as Topic; Drugs, Investigational; Glasgow Coma Scale; Guanidines; Humans; N-Methylaspartate; Neuroprotective Agents; Reference Values; Spinal Cord Injuries

1997

Trials

1 trial(s) available for aptiganel and Acute Brain Injuries

Article	Year
Clinical pharmacology of CNS 1102 in man. Annals of the New York Academy of Sciences, 1995, Sep-15, Volume: 765 Topics: Brain Injuries; Cardiovascular System; Cerebrovascular Circulation; Cerebrovascular Disorders; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Excitatory Amino Acid Antagonists; Guanidines; Humans; Male; Neuroprotective Agents	1995

Other Studies

2 other study(ies) available for aptiganel and Acute Brain Injuries

Article	Year
Prediction of outcome after moderate and severe traumatic brain injury: external validation of the International Mission on Prognosis and Analysis of Clinical Trials (IMPACT) and Corticoid Randomisation After Significant Head injury (CRASH) prognostic mod Critical care medicine, 2012, Volume: 40, Issue:5 Topics: Apolipoproteins E; Brain Injuries; Dronabinol; Glasgow Outcome Scale; Guanidines; Humans; Hypothermia, Induced; Logistic Models; Models, Statistical; Neuroprotective Agents; Prognosis; Registries; ROC Curve	2012
Protective effects of aptiganel HCl (Cerestat) following controlled cortical impact injury in the rat. Journal of neurotrauma, 1998, Volume: 15, Issue:3 Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Water; Brain Edema; Brain Injuries; Cerebral Cortex; Contusions; Excitatory Amino Acid Antagonists; Guanidines; Intracranial Pressure; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley	1998

Article

Year

Prediction of outcome after moderate and severe traumatic brain injury: external validation of the International Mission on Prognosis and Analysis of Clinical Trials (IMPACT) and Corticoid Randomisation After Significant Head injury (CRASH) prognostic mod

Critical care medicine, 2012, Volume: 40, Issue:5

Topics: Apolipoproteins E; Brain Injuries; Dronabinol; Glasgow Outcome Scale; Guanidines; Humans; Hypothermia, Induced; Logistic Models; Models, Statistical; Neuroprotective Agents; Prognosis; Registries; ROC Curve

2012

Protective effects of aptiganel HCl (Cerestat) following controlled cortical impact injury in the rat.

Journal of neurotrauma, 1998, Volume: 15, Issue:3

Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Water; Brain Edema; Brain Injuries; Cerebral Cortex; Contusions; Excitatory Amino Acid Antagonists; Guanidines; Intracranial Pressure; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley

1998