aptiganel has been researched along with Acute Brain Injuries in 4 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (75.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Butcher, I; Lecky, FE; Lingsma, HF; Lu, J; Maas, AI; McHugh, GS; Murray, GD; Perel, P; Roozenbeek, B; Steyerberg, EW; Weir, J | 1 |
Grosset, DG; Lees, KR; Muir, KW | 1 |
McBurney, RN | 1 |
Kroppenstedt, SN; Schneider, GH; Thomale, UW; Unterberg, AW | 1 |
1 review(s) available for aptiganel and Acute Brain Injuries
Article | Year |
---|---|
Development of the NMDA ion-channel blocker, aptiganel hydrochloride, as a neuroprotective agent for acute CNS injury.
Topics: Acute Disease; Brain Injuries; Cerebrovascular Disorders; Clinical Trials as Topic; Drugs, Investigational; Glasgow Coma Scale; Guanidines; Humans; N-Methylaspartate; Neuroprotective Agents; Reference Values; Spinal Cord Injuries | 1997 |
1 trial(s) available for aptiganel and Acute Brain Injuries
Article | Year |
---|---|
Clinical pharmacology of CNS 1102 in man.
Topics: Brain Injuries; Cardiovascular System; Cerebrovascular Circulation; Cerebrovascular Disorders; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Excitatory Amino Acid Antagonists; Guanidines; Humans; Male; Neuroprotective Agents | 1995 |
2 other study(ies) available for aptiganel and Acute Brain Injuries
Article | Year |
---|---|
Prediction of outcome after moderate and severe traumatic brain injury: external validation of the International Mission on Prognosis and Analysis of Clinical Trials (IMPACT) and Corticoid Randomisation After Significant Head injury (CRASH) prognostic mod
Topics: Apolipoproteins E; Brain Injuries; Dronabinol; Glasgow Outcome Scale; Guanidines; Humans; Hypothermia, Induced; Logistic Models; Models, Statistical; Neuroprotective Agents; Prognosis; Registries; ROC Curve | 2012 |
Protective effects of aptiganel HCl (Cerestat) following controlled cortical impact injury in the rat.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Water; Brain Edema; Brain Injuries; Cerebral Cortex; Contusions; Excitatory Amino Acid Antagonists; Guanidines; Intracranial Pressure; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 1998 |