aprindine has been researched along with Wolff-Parkinson-White Syndrome in 12 studies
Aprindine: A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
Wolff-Parkinson-White Syndrome: A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Four patients with supraventricular tachycardia associated with the Wolff-Parkinson-White syndrome were refractory to conventional pharmacological therapy and received aprindine hydrochloride intravenously and orally." | 7.65 | Suppression of refractory arrhythmias by aprindine in patients with the Wolff-Parkinson-White syndrome. ( Greene, HL; Reid, PR; Varghese, PJ, 1977) |
| "The effects of aprindine on atrial vulnerability were studied in 11 patients; 9 with paroxysmal atrial fibrillation (PAF), and 2 with Wolff-Parkinson-White syndrome, aged 19 to 69 (55." | 5.08 | Effects of aprindine on electrophysiological properties of the atrial muscle in man. ( Centurion, O; Hano, O; Hayano, M; Hirata, T; Isomoto, S; Kaibara, M; Konoe, A; Shimizu, A; Yano, K, 1995) |
| "Aprindine is a long-acting antiarrhythmic agent, effective when administered orally or intravenously in the treatment of ventricular arrhythmias of varying etiologies." | 4.76 | Aprindine. ( Danilo, P, 1979) |
| "Four patients with supraventricular tachycardia associated with the Wolff-Parkinson-White syndrome were refractory to conventional pharmacological therapy and received aprindine hydrochloride intravenously and orally." | 3.65 | Suppression of refractory arrhythmias by aprindine in patients with the Wolff-Parkinson-White syndrome. ( Greene, HL; Reid, PR; Varghese, PJ, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prystowsky, EN | 1 |
| Bauernfeind, RA | 1 |
| Swiryn, SP | 1 |
| Strasberg, B | 1 |
| Palileo, E | 1 |
| Scagliotti, D | 1 |
| Rosen, KM | 2 |
| Wang, HZ | 1 |
| Hano, O | 1 |
| Konoe, A | 1 |
| Hirata, T | 1 |
| Kaibara, M | 1 |
| Isomoto, S | 1 |
| Shimizu, A | 1 |
| Centurion, O | 1 |
| Hayano, M | 1 |
| Yano, K | 1 |
| Coumel, P | 1 |
| Krikler, D | 1 |
| Rosen, MR | 1 |
| Wellens, HJ | 1 |
| Zipes, DP | 2 |
| Danilo, P | 1 |
| Vergara, G | 1 |
| Disertori, M | 1 |
| Molinis, G | 1 |
| Inama, G | 1 |
| Antonini, L | 1 |
| Del Favero, A | 1 |
| Stefenelli, C | 1 |
| Furlanello, F | 1 |
| Reid, PR | 1 |
| Greene, HL | 1 |
| Varghese, PJ | 1 |
| Brisse, B | 1 |
| Bender, F | 1 |
| Gaum, WE | 1 |
| Foster, PR | 1 |
| Wu, D | 1 |
| Amat-Y-Leon, F | 1 |
| Noble, RJ | 1 |
| Hirao, K | 1 |
| Okishige, K | 1 |
| Suzuki, F | 1 |
| Hiejima, K | 1 |
| Kubota, K | 1 |
| Ikeda, T | 1 |
| Takata, S | 1 |
| Murakami, T | 1 |
| Nakamura, S | 1 |
| Fujiki, A | 1 |
| Higashino, A | 1 |
| Hattori, N | 1 |
2 reviews available for aprindine and Wolff-Parkinson-White Syndrome
| Article | Year |
|---|---|
Pharmacologic therapy of tachyarrhythmias in patients with Wolff-Parkinson-White syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Ajmaline; Amiodarone; Anilides; Aprindine; Atr | 1983 |
Aprindine.
Topics: Administration, Oral; Agranulocytosis; Animals; Aprindine; Arrhythmias, Cardiac; Autonomic Nervous S | 1979 |
1 trial available for aprindine and Wolff-Parkinson-White Syndrome
| Article | Year |
|---|---|
Effects of aprindine on electrophysiological properties of the atrial muscle in man.
Topics: Action Potentials; Adult; Aged; Aprindine; Atrial Fibrillation; Electrocardiography; Electrophysiolo | 1995 |
9 other studies available for aprindine and Wolff-Parkinson-White Syndrome
| Article | Year |
|---|---|
Electrophysiologic drug testing in prophylaxis of sporadic paroxysmal atrial fibrillation: technique, application, and efficacy in severely symptomatic preexcitation patients.
Topics: Administration, Oral; Adolescent; Adult; Aprindine; Atrial Fibrillation; Cardiac Pacing, Artificial; | 1982 |
[The therapeutic effect of aprindine in treating 9 cases of Wolff-Parkinson-White syndrome associated with auricular fibrillation (author's transl)].
Topics: Adult; Aprindine; Atrial Fibrillation; Female; Humans; Indenes; Male; Middle Aged; Wolff-Parkinson-W | 1982 |
Newer antiarrhythmic drugs.
Topics: Administration, Oral; Adult; Amiodarone; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Ca | 1978 |
[Evaluation of the electrophysiological effects of aprindine in man, with particular regard to the ventricular preexcitation syndrome (author's transl)].
Topics: Adult; Aged; Aprindine; Drug Evaluation; Electrocardiography; Female; Heart Conduction System; Human | 1979 |
Suppression of refractory arrhythmias by aprindine in patients with the Wolff-Parkinson-White syndrome.
Topics: Administration, Oral; Adult; Aged; Aprindine; Electrocardiography; Female; Humans; Indenes; Infusion | 1977 |
[Oral treatment of arrhythmias in the WPW and LGL-syndrome using Amidonal].
Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Aprindine; Female; Humans; Indenes; Male; Middl | 1977 |
Aprindine for treatment of supraventricular tachycardias. With particular application to Wolff-Parkinson-White syndrome.
Topics: Adult; Aprindine; Atrial Fibrillation; Atrial Flutter; Electrocardiography; Electrophysiology; Femal | 1977 |
Combination therapy with aprindine and verapamil for paroxysmal supraventricular tachycardia as assessed by transesophageal atrial pacing.
Topics: Administration, Oral; Adult; Aged; Aprindine; Drug Administration Schedule; Drug Therapy, Combinatio | 1991 |
[Effects of aprindine on the induction and termination of supraventricular tachycardia in patients with accessory pathway syndrome].
Topics: Adult; Aprindine; Female; Humans; Indenes; Injections, Intravenous; Male; Middle Aged; Tachycardia; | 1985 |