aprindine has been researched along with Tachycardia in 31 studies
Aprindine: A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five cases of aprindine-induced polymorphous ventricular tachycardia (torsade de pointes) are presented." | 9.05 | Aprindine-induced polymorphous ventricular tachycardia. ( Hai, HA; Kehoe, R; Rosen, K; Scagliotti, D; Strasberg, B, 1982) |
| "Aprindine hydrochloride (aprindine) was administered orally in 17 Japanese patients with supraventricular or ventricular tachyarrhythmias, and the clinical effects and plasma concentration levels were evaluated." | 7.67 | [Clinical effects and plasma concentration levels of aprindine hydrochloride in patients with tachyarrhythmias]. ( Kasahara, S; Komatsu, Y; Miura, M; Miyazaki, Y; Miyazawa, Y; Mizobe, H; Shibata, N; Shoda, M, 1989) |
| "Aprindine was administered both intravenously and orally to 25 patients with ventricular tachycardia refractory to conventional antiarrhythmic agents to test the hypothesis that the response to intravenous aprindine predicts the response to oral aprindine." | 7.66 | Ventricular tachycardia: prediction of response to oral aprindine with intravenous aprindine. ( Bauernfeind, R; Dhingra, RC; Kehoe, R; Palileo, E; Prechel, D; Rosen, KM; Strasberg, B; Swiryn, S; Wyndham, CR, 1981) |
| "Aprindine hydrochloride was administered IV and orally to 20 dogs with ventricular tachycardia." | 7.66 | Aprindine for treatment of ventricular arrhythmias in the dog. ( Bonagura, JD; Muir, WW, 1982) |
| " Twenty-seven patients with refractory ventricular tachycardia were studied to determine whether acute suppression of the repetitive ventricular response by aprindine predicts long-term effectiveness of this agent." | 7.66 | Suppression of the repetitive ventricular response: an index of long-term antiarrhythmic effectiveness of aprindine for ventricular tachycardia in man. ( Greene, HL; Reid, PR; Schaeffer, AH, 1978) |
| "Twenty-three patients with recurrent ventricular tachycardia or ventricular fibrillation, or both, were treated with aprindine, a new antiarrhythmic agent." | 7.65 | Treatment of recurrent ventricular tachycardia and fibrillation with aprindine. ( Fasola, AF; Noble, RJ; Zipes, DP, 1977) |
| "Four patients with supraventricular tachycardia associated with the Wolff-Parkinson-White syndrome were refractory to conventional pharmacological therapy and received aprindine hydrochloride intravenously and orally." | 7.65 | Suppression of refractory arrhythmias by aprindine in patients with the Wolff-Parkinson-White syndrome. ( Greene, HL; Reid, PR; Varghese, PJ, 1977) |
| "Aprindine was effective in five cases, and it failed in two." | 5.27 | Aprindine therapy for refractory ventricular tachycardia. ( Carleton, RA; Chown, M; Khan, AH, 1983) |
| "Oral long-term treatment with various antiarrhythmic drugs (aprindine, mexiletine, disopyramide, amiodarone) was assessed in 82 patients with recurrent tachycardias demonstrated in the ECG using programmed ventricular stimulation." | 5.05 | [Long-term drug therapy in ventricular cardiac arrhythmias. Is an improvement of the prognosis possible?]. ( Lüderitz, B; Manz, M; Steinbeck, G, 1983) |
| "Five cases of aprindine-induced polymorphous ventricular tachycardia (torsade de pointes) are presented." | 5.05 | Aprindine-induced polymorphous ventricular tachycardia. ( Hai, HA; Kehoe, R; Rosen, K; Scagliotti, D; Strasberg, B, 1982) |
| "We present a case treated with aprindine and metoprolol combined with a DDD type pacemaker for repetitive monomorphic ventricular tachycardia." | 3.68 | [A case of repetitive monomorphic ventricular tachycardia]. ( Komatsu, C; Kubouchi, Y; Kudou, S; Kurusu, O; Nomoto, J; Okamura, T; Sanada, T; Tanoiri, T; Tokuhisa, Y, 1992) |
| "Aprindine hydrochloride (aprindine) was administered orally in 17 Japanese patients with supraventricular or ventricular tachyarrhythmias, and the clinical effects and plasma concentration levels were evaluated." | 3.67 | [Clinical effects and plasma concentration levels of aprindine hydrochloride in patients with tachyarrhythmias]. ( Kasahara, S; Komatsu, Y; Miura, M; Miyazaki, Y; Miyazawa, Y; Mizobe, H; Shibata, N; Shoda, M, 1989) |
| "Sixty-four patients with a history of ventricular tachycardia and ventricular fibrillation refractory to conventional therapy received aprindine to abolish recurrent episodes of symptomatic ventricular tachycardia." | 3.67 | The utility of aprindine blood levels in the management of ventricular arrhythmias. ( Kallman, CH; Reid, PR; Vlay, SC, 1985) |
| "Aprindine was administered both intravenously and orally to 25 patients with ventricular tachycardia refractory to conventional antiarrhythmic agents to test the hypothesis that the response to intravenous aprindine predicts the response to oral aprindine." | 3.66 | Ventricular tachycardia: prediction of response to oral aprindine with intravenous aprindine. ( Bauernfeind, R; Dhingra, RC; Kehoe, R; Palileo, E; Prechel, D; Rosen, KM; Strasberg, B; Swiryn, S; Wyndham, CR, 1981) |
| "Aprindine hydrochloride was administered IV and orally to 20 dogs with ventricular tachycardia." | 3.66 | Aprindine for treatment of ventricular arrhythmias in the dog. ( Bonagura, JD; Muir, WW, 1982) |
| " Twenty-seven patients with refractory ventricular tachycardia were studied to determine whether acute suppression of the repetitive ventricular response by aprindine predicts long-term effectiveness of this agent." | 3.66 | Suppression of the repetitive ventricular response: an index of long-term antiarrhythmic effectiveness of aprindine for ventricular tachycardia in man. ( Greene, HL; Reid, PR; Schaeffer, AH, 1978) |
| "Twenty-three patients with recurrent ventricular tachycardia or ventricular fibrillation, or both, were treated with aprindine, a new antiarrhythmic agent." | 3.65 | Treatment of recurrent ventricular tachycardia and fibrillation with aprindine. ( Fasola, AF; Noble, RJ; Zipes, DP, 1977) |
| "Four patients with supraventricular tachycardia associated with the Wolff-Parkinson-White syndrome were refractory to conventional pharmacological therapy and received aprindine hydrochloride intravenously and orally." | 3.65 | Suppression of refractory arrhythmias by aprindine in patients with the Wolff-Parkinson-White syndrome. ( Greene, HL; Reid, PR; Varghese, PJ, 1977) |
| "Aprindine is a very effective antiarrhythmic agent with a narrow therapeutic-toxic ratio." | 2.36 | Studies with aprindine. ( Elharrar, V; Gilmour, RF; Heger, JJ; Prystowsky, EN; Zipes, DP, 1980) |
| " If side effects intervene that may cause continued therapy to be intolerable, changing the antiarrhythmic agent, as opposed to decreasing the dosage to an ineffective range, may be appropriate." | 1.27 | New directions in antiarrhythmic drug therapy. ( Somberg, JC, 1984) |
| "Aprindine was effective in five cases, and it failed in two." | 1.27 | Aprindine therapy for refractory ventricular tachycardia. ( Carleton, RA; Chown, M; Khan, AH, 1983) |
| "Aprindine was given orally to an 88-year-old patient with atrial fibrillation and ventricular premature depolarizations." | 1.27 | Torsade des pointes and aprindine. ( Kontoyannis, DA; Moulopoulos, SD; Sideris, DA, 1985) |
| " It may, therefore, be concluded that in patients with otherwise normal hearts aprindin applied in a dosage sufficient to stop the SVT, does not exhibit noteworthy inotropic side effects." | 1.26 | [Changes in hemodynamics and contractility during supraventricular tachycardias and after electrical or aprindin-induced termination (author's transl)]. ( Merle, H; Schlepper, M; Weppner, HG, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (96.77) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prystowsky, EN | 4 |
| Somberg, JC | 1 |
| Kienzle, MG | 1 |
| Williams, PD | 1 |
| Zygmont, D | 1 |
| Doherty, JU | 1 |
| Josephson, ME | 1 |
| Lüderitz, B | 2 |
| Zipes, DP | 7 |
| Elharrar, V | 1 |
| Gilmour, RF | 1 |
| Heger, JJ | 3 |
| Manz, M | 1 |
| Steinbeck, G | 1 |
| Strasberg, B | 2 |
| Palileo, E | 1 |
| Prechel, D | 1 |
| Bauernfeind, R | 1 |
| Swiryn, S | 1 |
| Wyndham, CR | 1 |
| Dhingra, RC | 1 |
| Kehoe, R | 2 |
| Rosen, KM | 2 |
| Rinkenberger, RL | 1 |
| Jackman, WM | 1 |
| Naccarelli, GV | 1 |
| Khan, AH | 1 |
| Carleton, RA | 1 |
| Chown, M | 1 |
| Scagliotti, D | 1 |
| Hai, HA | 1 |
| Rosen, K | 1 |
| Southworth, WF | 1 |
| Ruffy, R | 1 |
| Muir, WW | 1 |
| Bonagura, JD | 1 |
| Theisen, K | 1 |
| Fasola, AF | 1 |
| Noble, RJ | 2 |
| Coumel, P | 1 |
| Krikler, D | 1 |
| Rosen, MR | 1 |
| Wellens, HJ | 1 |
| Troup, PJ | 1 |
| Reid, PR | 4 |
| Greene, HL | 3 |
| Varghese, PJ | 1 |
| Wei, JY | 1 |
| Bulkley, BH | 1 |
| Schaeffer, AH | 2 |
| Gaum, WE | 1 |
| Foster, PR | 1 |
| Wu, D | 1 |
| Amat-Y-Leon, F | 1 |
| Weppner, HG | 1 |
| Merle, H | 1 |
| Schlepper, M | 1 |
| Gerlach, D | 1 |
| Lüllmann, H | 1 |
| Schaefer, J | 1 |
| Steinbach, K | 1 |
| Kurusu, O | 1 |
| Kudou, S | 1 |
| Nomoto, J | 1 |
| Tanoiri, T | 1 |
| Tokuhisa, Y | 1 |
| Kubouchi, Y | 1 |
| Sanada, T | 1 |
| Komatsu, C | 1 |
| Okamura, T | 1 |
| Stroobandt, R | 1 |
| Holvoet, G | 1 |
| Verbeke, N | 1 |
| Kesteloot, H | 1 |
| Sideris, DA | 1 |
| Kontoyannis, DA | 1 |
| Moulopoulos, SD | 1 |
| Kasahara, S | 1 |
| Shibata, N | 1 |
| Mizobe, H | 1 |
| Shoda, M | 1 |
| Miyazaki, Y | 1 |
| Miura, M | 1 |
| Miyazawa, Y | 1 |
| Komatsu, Y | 1 |
| Vlay, SC | 1 |
| Kallman, CH | 1 |
| Kubota, K | 1 |
| Ikeda, T | 1 |
| Takata, S | 1 |
| Murakami, T | 1 |
| Nakamura, S | 1 |
| Fujiki, A | 1 |
| Higashino, A | 1 |
| Hattori, N | 1 |
| Adinolfi, L | 1 |
| Bonaduce, D | 1 |
| Dote, I | 1 |
| Golia, B | 1 |
| Masullo, LA | 1 |
| Chiariello, M | 1 |
3 reviews available for aprindine and Tachycardia
| Article | Year |
|---|---|
Pharmacologic therapy of tachyarrhythmias in patients with Wolff-Parkinson-White syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Ajmaline; Amiodarone; Anilides; Aprindine; Atr | 1983 |
Antiarrhythmic drug therapy for sustained ventricular tachycardia.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetami | 1984 |
Studies with aprindine.
Topics: Agranulocytosis; Animals; Aprindine; Arrhythmias, Cardiac; Cholestasis; Dogs; Electrophysiology; Hum | 1980 |
3 trials available for aprindine and Tachycardia
| Article | Year |
|---|---|
[Long-term drug therapy in ventricular cardiac arrhythmias. Is an improvement of the prognosis possible?].
Topics: Adult; Aged; Amiodarone; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; Long-Term Care; Mexi | 1983 |
Aprindine-induced polymorphous ventricular tachycardia.
Topics: Aged; Aprindine; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrocardiography; Female; Humans | 1982 |
Effects of intravenous sotalol, aprindine and the combination of sotalol and aprindine on chronic high frequency ventricular arrhythmias in man.
Topics: Aged; Aged, 80 and over; Aprindine; Cardiac Complexes, Premature; Clinical Trials as Topic; Drug The | 1987 |
25 other studies available for aprindine and Tachycardia
| Article | Year |
|---|---|
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benz | 1984 |
[Drug therapy of arrhythmia in coronary cardiopathy].
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Comp | 1983 |
Drug therapy of cardiac arrhythmias.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Biological Availabili | 1983 |
Ventricular tachycardia: prediction of response to oral aprindine with intravenous aprindine.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aprindine; Dose-Response Relationship, Drug; Female; | 1981 |
Drug conversion of nonsustained ventricular tachycardia to sustained ventricular tachycardia during serial electrophysiologic studies: identification of drugs that exacerbate tachycardia and potential mechanisms.
Topics: Adult; Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Cardiac Catheterization; Disop | 1982 |
Aprindine therapy for refractory ventricular tachycardia.
Topics: Agranulocytosis; Aprindine; Central Nervous System Diseases; Electrocardiography; Follow-Up Studies; | 1983 |
Unusual electrophysiologic effects of aprindine.
Topics: Aprindine; Electrocardiography; Female; Heart Block; Humans; Indenes; Middle Aged; Sinoatrial Block; | 1982 |
Aprindine for treatment of ventricular arrhythmias in the dog.
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Dog Diseases; Dogs; Female; Heart; Heart Ventricles; Hemod | 1982 |
[Drug therapy of tachyarrhythmias (author's transl)].
Topics: Action Potentials; Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Aprind | 1978 |
Treatment of recurrent ventricular tachycardia and fibrillation with aprindine.
Topics: Administration, Oral; Adult; Aged; Aprindine; Cardiac Complexes, Premature; Drug Administration Sche | 1977 |
Newer antiarrhythmic drugs.
Topics: Administration, Oral; Adult; Amiodarone; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Ca | 1978 |
Aprindine treatment of recurrent ventricular tachycardia in patients with mitral valve prolapse.
Topics: Adult; Aprindine; Electrocardiography; Female; Heart Ventricles; Humans; Indenes; Male; Middle Aged; | 1979 |
Suppression of refractory arrhythmias by aprindine in patients with the Wolff-Parkinson-White syndrome.
Topics: Administration, Oral; Adult; Aged; Aprindine; Electrocardiography; Female; Humans; Indenes; Infusion | 1977 |
Mitral-valve prolapse syndrome and recurrent ventricular tachyarrhythmias: a malignant variant refractory to conventional drug therapy.
Topics: Adult; Aged; Aprindine; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Male; Middle Aged | 1978 |
Suppression of the repetitive ventricular response: an index of long-term antiarrhythmic effectiveness of aprindine for ventricular tachycardia in man.
Topics: Administration, Oral; Adult; Aged; Aprindine; Cardiac Pacing, Artificial; Drug Evaluation; Electroca | 1978 |
Aprindine for treatment of supraventricular tachycardias. With particular application to Wolff-Parkinson-White syndrome.
Topics: Adult; Aprindine; Atrial Fibrillation; Atrial Flutter; Electrocardiography; Electrophysiology; Femal | 1977 |
[Changes in hemodynamics and contractility during supraventricular tachycardias and after electrical or aprindin-induced termination (author's transl)].
Topics: Adult; Aprindine; Blood Pressure; Electric Stimulation; Female; Hemodynamics; Humans; Indenes; Male; | 1976 |
[Special problems of antiarrhythmic therapy as shown on the example of a tachycardia with atrioventricular dissociation].
Topics: Adolescent; Aprindine; Basal Ganglia Diseases; Blood Pressure; Female; Glucocorticoids; Humans; Tach | 1975 |
[Treatment of arrhythmia in general practice].
Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; H | 1975 |
[A case of repetitive monomorphic ventricular tachycardia].
Topics: Aprindine; Cardiac Pacing, Artificial; Cardiomyopathy, Hypertrophic; Drug Therapy, Combination; Elec | 1992 |
Torsade des pointes and aprindine.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Cardiac Complexes, Premature; Electrocardiography; Humans; | 1985 |
[Clinical effects and plasma concentration levels of aprindine hydrochloride in patients with tachyarrhythmias].
Topics: Administration, Oral; Aged; Aprindine; Drug Evaluation; Female; Humans; Indenes; Male; Middle Aged; | 1989 |
The utility of aprindine blood levels in the management of ventricular arrhythmias.
Topics: Aprindine; Dose-Response Relationship, Drug; Female; Humans; Indenes; Male; Middle Aged; Recurrence; | 1985 |
[Effects of aprindine on the induction and termination of supraventricular tachycardia in patients with accessory pathway syndrome].
Topics: Adult; Aprindine; Female; Humans; Indenes; Injections, Intravenous; Male; Middle Aged; Tachycardia; | 1985 |
[Ventricular tachycardia].
Topics: Amiodarone; Aprindine; Digitalis Glycosides; Electrocardiography; Heart Aneurysm; Heart Ventricles; | 1985 |