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aprindine and Death, Sudden

aprindine has been researched along with Death, Sudden in 8 studies

Aprindine: A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.

Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.

Research Excerpts

ExcerptRelevanceReference
"A study was designed to investigate whether long-term use of aprindine can prevent sudden death from primary ventricular fibrillation."5.04Design of a study to evaluate drug therapy of serious ventricular rhythm disturbances after an acute myocardial infarction. ( Bogaert, M; Glaser, B; Hagemeijer, F; van Durme, JP, 1977)
"Aprindine was chosen because of its long half-life, few side effects, and antiarrhythmic efficacy."2.66Prophylactic antiarrhythmic therapy of high-risk survivors of myocardial infarction: lower mortality at 1 month but not at 1 year. ( Achuff, SC; Baughman, KL; Becker, L; Chandra, NC; Gerstenblith, G; Gottlieb, SH; Heck, C; Henley, S; Humphries, JO; Mellits, ED, 1987)
"Many sudden deaths are presumed to be due to an arrhythmia, but the drugs best known for antiarrhythmic activity, the local anesthetic agents, have not been suitable prophylactic agents because of their toxicities and other undesirable pharmacologic characteristics."2.65Selection of an antiarrhythmic drug for a sudden-death-prevention trial. ( Duff, HJ; Oates, JA; Roden, DM; Woosley, RL, 1982)
" If side effects intervene that may cause continued therapy to be intolerable, changing the antiarrhythmic agent, as opposed to decreasing the dosage to an ineffective range, may be appropriate."1.27New directions in antiarrhythmic drug therapy. ( Somberg, JC, 1984)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Somberg, JC1
Woosley, RL1
Roden, DM1
Duff, HJ1
Oates, JA1
Lubsen, J1
Winkle, RA1
Hagemeijer, F1
Glaser, B1
van Durme, JP1
Bogaert, M1
Koch-Weser, J1
Podrid, PJ1
Gottlieb, SH1
Achuff, SC1
Mellits, ED1
Gerstenblith, G1
Baughman, KL1
Becker, L1
Chandra, NC1
Henley, S1
Humphries, JO1
Heck, C1

Reviews

2 reviews available for aprindine and Death, Sudden

ArticleYear
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
    Advances in cardiology, 1978, Volume: 25

    Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death,

1978
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
    Cardiovascular clinics, 1985, Volume: 15, Issue:3

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple

1985

Trials

5 trials available for aprindine and Death, Sudden

ArticleYear
Selection of an antiarrhythmic drug for a sudden-death-prevention trial.
    American heart journal, 1982, Volume: 103, Issue:4 Pt 2

    Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneac

1982
Design of a study to evaluate drug therapy of serious ventricular rhythm disturbances after an acute myocardial infarction.
    European journal of cardiology, 1977, Volume: 6, Issue:4

    Topics: Aprindine; Clinical Trials as Topic; Computers; Death, Sudden; Follow-Up Studies; Humans; Indenes; I

1977
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
    Advances in cardiology, 1978, Volume: 25

    Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death,

1978
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
    Cardiovascular clinics, 1985, Volume: 15, Issue:3

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple

1985
Prophylactic antiarrhythmic therapy of high-risk survivors of myocardial infarction: lower mortality at 1 month but not at 1 year.
    Circulation, 1987, Volume: 75, Issue:4

    Topics: Aprindine; Arrhythmias, Cardiac; Capsules; Clinical Trials as Topic; Death, Sudden; Double-Blind Met

1987

Other Studies

3 other studies available for aprindine and Death, Sudden

ArticleYear
New directions in antiarrhythmic drug therapy.
    The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4

    Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benz

1984
Secondary preventive trials with antiarrhythmic agents: are we asking the right question?
    European heart journal, 1984, Volume: 5 Suppl B

    Topics: Anti-Arrhythmia Agents; Aprindine; Clinical Trials as Topic; Death, Sudden; Humans; Ventricular Fibr

1984
Clinical efficacy of antiarrhythmic drugs in prevention of sudden coronary death.
    Annals of the New York Academy of Sciences, 1982, Volume: 382

    Topics: Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Angiography; Coronary Artery Bypas

1982
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