aprindine and Death, Sudden
aprindine has been researched along with Death, Sudden in 8 studies
Aprindine: A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"A study was designed to investigate whether long-term use of aprindine can prevent sudden death from primary ventricular fibrillation." | 5.04 | Design of a study to evaluate drug therapy of serious ventricular rhythm disturbances after an acute myocardial infarction. ( Bogaert, M; Glaser, B; Hagemeijer, F; van Durme, JP, 1977) |
"Aprindine was chosen because of its long half-life, few side effects, and antiarrhythmic efficacy." | 2.66 | Prophylactic antiarrhythmic therapy of high-risk survivors of myocardial infarction: lower mortality at 1 month but not at 1 year. ( Achuff, SC; Baughman, KL; Becker, L; Chandra, NC; Gerstenblith, G; Gottlieb, SH; Heck, C; Henley, S; Humphries, JO; Mellits, ED, 1987) |
"Many sudden deaths are presumed to be due to an arrhythmia, but the drugs best known for antiarrhythmic activity, the local anesthetic agents, have not been suitable prophylactic agents because of their toxicities and other undesirable pharmacologic characteristics." | 2.65 | Selection of an antiarrhythmic drug for a sudden-death-prevention trial. ( Duff, HJ; Oates, JA; Roden, DM; Woosley, RL, 1982) |
" If side effects intervene that may cause continued therapy to be intolerable, changing the antiarrhythmic agent, as opposed to decreasing the dosage to an ineffective range, may be appropriate." | 1.27 | New directions in antiarrhythmic drug therapy. ( Somberg, JC, 1984) |
Research
Studies (8)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Somberg, JC | 1 |
Woosley, RL | 1 |
Roden, DM | 1 |
Duff, HJ | 1 |
Oates, JA | 1 |
Lubsen, J | 1 |
Winkle, RA | 1 |
Hagemeijer, F | 1 |
Glaser, B | 1 |
van Durme, JP | 1 |
Bogaert, M | 1 |
Koch-Weser, J | 1 |
Podrid, PJ | 1 |
Gottlieb, SH | 1 |
Achuff, SC | 1 |
Mellits, ED | 1 |
Gerstenblith, G | 1 |
Baughman, KL | 1 |
Becker, L | 1 |
Chandra, NC | 1 |
Henley, S | 1 |
Humphries, JO | 1 |
Heck, C | 1 |
Reviews
2 reviews available for aprindine and Death, Sudden
Article | Year |
---|---|
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, | 1978 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple | 1985 |
Trials
5 trials available for aprindine and Death, Sudden
Article | Year |
---|---|
Selection of an antiarrhythmic drug for a sudden-death-prevention trial.
Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneac | 1982 |
Design of a study to evaluate drug therapy of serious ventricular rhythm disturbances after an acute myocardial infarction.
Topics: Aprindine; Clinical Trials as Topic; Computers; Death, Sudden; Follow-Up Studies; Humans; Indenes; I | 1977 |
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, | 1978 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple | 1985 |
Prophylactic antiarrhythmic therapy of high-risk survivors of myocardial infarction: lower mortality at 1 month but not at 1 year.
Topics: Aprindine; Arrhythmias, Cardiac; Capsules; Clinical Trials as Topic; Death, Sudden; Double-Blind Met | 1987 |
Other Studies
3 other studies available for aprindine and Death, Sudden
Article | Year |
---|---|
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benz | 1984 |
Secondary preventive trials with antiarrhythmic agents: are we asking the right question?
Topics: Anti-Arrhythmia Agents; Aprindine; Clinical Trials as Topic; Death, Sudden; Humans; Ventricular Fibr | 1984 |
Clinical efficacy of antiarrhythmic drugs in prevention of sudden coronary death.
Topics: Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Angiography; Coronary Artery Bypas | 1982 |