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aprindine and Coronary Heart Disease

aprindine has been researched along with Coronary Heart Disease in 14 studies

Aprindine: A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.

Research Excerpts

ExcerptRelevanceReference
"A multicenter, placebo-controlled, randomized, double-blind trial compared the preventive effect of aprindine and digoxin on the recurrence of atrial fibrillation (AF) with placebo, and also compare the effectiveness of these 2 drugs in the prevention of AF."9.10Double-blind placebo-controlled trial of aprindine and digoxin for the prevention of symptomatic atrial fibrillation. ( Atarashi, H; Fukunami, M; Hamada, C; Inoue, H; Origasa, H; Sugi, K, 2002)
"A multicenter, placebo-controlled, randomized, double-blind trial compared the preventive effect of aprindine and digoxin on the recurrence of atrial fibrillation (AF) with placebo, and also compare the effectiveness of these 2 drugs in the prevention of AF."5.10Double-blind placebo-controlled trial of aprindine and digoxin for the prevention of symptomatic atrial fibrillation. ( Atarashi, H; Fukunami, M; Hamada, C; Inoue, H; Origasa, H; Sugi, K, 2002)
"The effect of intravenously administered aprindine (AC1802) as a prophylactic agent against ventricular arrhythmias was studied in pigs."3.65Cardiovascular and antiarrhythmic effects of aprindine (AC1802) during partial occlusion of a coronary artery in the pig. ( Hugenholtz, PG; Remme, WJ; Verdouw, PD, 1977)
"The influence of the excitability threshold on the ventricular fibrillation threshold was studied in dogs during myocardial ischemia and potassium and aprindine infusion."3.65Influence of excitability on the ventricular fibrillation threshold in dogs. ( Elharrar, V; Gaum, WE; Walker, PD; Zipes, DP, 1977)
"After treatment of ischemia and/or failure, specific antiarrhythmic agents, conventional and investigational, alone or in combination, are systematically selected."1.26Ventricular ectopy: etiology, evaluation, and therapy. ( Reid, PR; Vlay, SC, 1982)
"The incidence of ventricular arrhythmias was increased by aprindine (from 1 in 11 to 8 in 11 dogs), decresed by verapamil (from 3 in 7 to 0 in 7 dogs) and was not changes by quinidine or isoproterenol."1.26Effect of drugs on conduction delay and incidence of ventricular arrhythmias induced by acute coronary occlusion in dogs. ( Elharrar, V; Gaum, WE; Zipes, DP, 1977)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vlay, SC1
Reid, PR1
Lüderitz, B2
Manz, M1
Steinbeck, G1
Ferro, G3
Chiariello, M3
Tari, MG2
Vigorito, C1
Ungaro, B1
Condorelli, M3
Winkle, RA1
Nattel, S1
Pedersen, DH1
Zipes, DP3
Atarashi, H1
Inoue, H1
Fukunami, M1
Sugi, K1
Hamada, C1
Origasa, H1
Niederberger, M1
Gasic, S1
Haber, P1
Santinelli, V2
Stanislao, M1
Elharrar, V2
Gaum, WE2
Verdouw, PD1
Remme, WJ1
Hugenholtz, PG1
Walker, PD1
Tanabe, T1
Yoshikawa, H1
Tagawa, R1
Furuya, H1
Ide, M1
Goto, Y1

Trials

1 trial available for aprindine and Coronary Heart Disease

ArticleYear
Double-blind placebo-controlled trial of aprindine and digoxin for the prevention of symptomatic atrial fibrillation.
    Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:6

    Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Coronary Disease; Diabetic Angiopathie

2002

Other Studies

13 other studies available for aprindine and Coronary Heart Disease

ArticleYear
Ventricular ectopy: etiology, evaluation, and therapy.
    The American journal of medicine, 1982, Volume: 73, Issue:6

    Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Aprindine; Arrhyth

1982
[Drug therapy of arrhythmia in coronary cardiopathy].
    La Clinica terapeutica, 1983, Apr-15, Volume: 105, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Comp

1983
[Ventricular heart-rhythm disorders - sudden cardiac death: results of long-term drug therapy].
    Verhandlungen der Deutschen Gesellschaft fur Herz- und Kreislaufforschung, 1983, Volume: 49

    Topics: Adult; Aged; Aprindine; Arrhythmias, Cardiac; Coronary Disease; Female; Germany, West; Humans; Inden

1983
Intropic effects of several antiarrhythmic drugs.
    Japanese heart journal, 1983, Volume: 24, Issue:3

    Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Blood Pressure; Bunaftine; Coronary Disease; Disopyrami

1983
Clinical efficacy of antiarrhythmic drugs in prevention of sudden coronary death.
    Annals of the New York Academy of Sciences, 1982, Volume: 382

    Topics: Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Angiography; Coronary Artery Bypas

1982
Alterations in regional myocardial distribution and arrhythmogenic effects of aprindine produced by coronary artery occlusion in the dog.
    Cardiovascular research, 1981, Volume: 15, Issue:2

    Topics: Animals; Aprindine; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Dogs; Female; Hear

1981
[Proceedings: Effect of aprindine on extrasystole and hemodynamics in an exertion study].
    Zeitschrift fur Kardiologie, 1975, Volume: Suppl 2

    Topics: Adolescent; Adult; Aged; Aprindine; Cardiac Complexes, Premature; Coronary Disease; Heart Rate; Hemo

1975
[Effects of intravenous aprindine on cardiac performance in patients with various degrees of myocardial damage].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:6

    Topics: Adult; Aprindine; Coronary Disease; Heart Rate; Humans; Indenes; Injections, Intravenous; Male; Midd

1978
[Effects of intravenous administration of aprindine on electrophysiological parameters in patients with myocardial damage].
    Bollettino della Societa italiana di cardiologia, 1979, Volume: 24, Issue:7

    Topics: Aprindine; Cardiomyopathies; Coronary Disease; Electrocardiography; Humans; Indenes; Male; Middle Ag

1979
Effect of drugs on conduction delay and incidence of ventricular arrhythmias induced by acute coronary occlusion in dogs.
    The American journal of cardiology, 1977, Volume: 39, Issue:4

    Topics: Animals; Aprindine; Arrhythmias, Cardiac; Coronary Disease; Disease Models, Animal; Dogs; Heart Cond

1977
Cardiovascular and antiarrhythmic effects of aprindine (AC1802) during partial occlusion of a coronary artery in the pig.
    Cardiovascular research, 1977, Volume: 11, Issue:4

    Topics: Animals; Aprindine; Arrhythmias, Cardiac; Carbon Dioxide; Coronary Disease; Indenes; Swine; Ventricu

1977
Influence of excitability on the ventricular fibrillation threshold in dogs.
    The American journal of cardiology, 1977, Volume: 40, Issue:6

    Topics: Animals; Aprindine; Cardiac Pacing, Artificial; Coronary Disease; Dogs; Female; Heart Ventricles; Ma

1977
Evaluation of antiarrhythmic drug efficacy using holter electrocardiographic technique.
    Japanese circulation journal, 1985, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Complexes,

1985