aprindine has been researched along with Atrial Fibrillation in 18 studies
Aprindine: A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate pharmacological cardioversion of long-lasting persistent atrial fibrillation (AF) using bepridil in terms of recovery of atrial mechanical function and maintenance of sinus rhythm." | 9.11 | Maintenance of sinus rhythm and recovery of atrial mechanical function after cardioversion with bepridil or in combination with aprindine in long-lasting persistent atrial fibrillation. ( Fujiki, A; Hirai, T; Inoue, H; Mizumaki, K; Nakagawa, K; Sakabe, M; Tsuneda, T, 2004) |
| "The aim of this study was to investigate the efficacy and safety of bepridil (a multichannel blocker including several potassium channels) for conversion of long-lasting atrial fibrillation (AF)." | 9.10 | Usefulness and safety of bepridil in converting persistent atrial fibrillation to sinus rhythm. ( Fujiki, A; Inoue, H; Mizumaki, K; Sugao, M; Tsuneda, T, 2003) |
| "A multicenter, placebo-controlled, randomized, double-blind trial compared the preventive effect of aprindine and digoxin on the recurrence of atrial fibrillation (AF) with placebo, and also compare the effectiveness of these 2 drugs in the prevention of AF." | 9.10 | Double-blind placebo-controlled trial of aprindine and digoxin for the prevention of symptomatic atrial fibrillation. ( Atarashi, H; Fukunami, M; Hamada, C; Inoue, H; Origasa, H; Sugi, K, 2002) |
| "The relationship between the efficacy of the anticholinergic action of disopyramide, cibenzoline and aprindine and age was examined in patients with paroxysmal and persistent atrial fibrillation." | 7.72 | [Comparison of the efficacies of disopyramide, cibenzoline and aprindine for the termination of paroxysmal and persistent atrial fibrillation in elderly and non-elderly patients]. ( Abe, N; Horiuchi, D; Kameda, K; Komatsu, T; Nakamura, S; Oikawa, K; Okumura, K; Owada, S; Suzuki, O; Tomita, H; Yomogida, K, 2003) |
| "Bepridil alone or in combination with aprindine converted long lasting persistent AF in association with an increase in both FCL and FOI." | 6.71 | Drug-induced changes in fibrillation cycle length and organization index can predict chemical cardioversion of long-lasting atrial fibrillation with bepridil alone or in combination with aprindine. ( Fujiki, A; Inoue, H; Iwamoto, J; Mizumaki, K; Nishida, K; Sakabe, M; Sugao, M; Tsuneda, T, 2004) |
| "The aim of this study was to evaluate pharmacological cardioversion of long-lasting persistent atrial fibrillation (AF) using bepridil in terms of recovery of atrial mechanical function and maintenance of sinus rhythm." | 5.11 | Maintenance of sinus rhythm and recovery of atrial mechanical function after cardioversion with bepridil or in combination with aprindine in long-lasting persistent atrial fibrillation. ( Fujiki, A; Hirai, T; Inoue, H; Mizumaki, K; Nakagawa, K; Sakabe, M; Tsuneda, T, 2004) |
| "The aim of this study was to investigate the efficacy and safety of bepridil (a multichannel blocker including several potassium channels) for conversion of long-lasting atrial fibrillation (AF)." | 5.10 | Usefulness and safety of bepridil in converting persistent atrial fibrillation to sinus rhythm. ( Fujiki, A; Inoue, H; Mizumaki, K; Sugao, M; Tsuneda, T, 2003) |
| "A multicenter, placebo-controlled, randomized, double-blind trial compared the preventive effect of aprindine and digoxin on the recurrence of atrial fibrillation (AF) with placebo, and also compare the effectiveness of these 2 drugs in the prevention of AF." | 5.10 | Double-blind placebo-controlled trial of aprindine and digoxin for the prevention of symptomatic atrial fibrillation. ( Atarashi, H; Fukunami, M; Hamada, C; Inoue, H; Origasa, H; Sugi, K, 2002) |
| "The effects of aprindine on atrial vulnerability were studied in 11 patients; 9 with paroxysmal atrial fibrillation (PAF), and 2 with Wolff-Parkinson-White syndrome, aged 19 to 69 (55." | 5.08 | Effects of aprindine on electrophysiological properties of the atrial muscle in man. ( Centurion, O; Hano, O; Hayano, M; Hirata, T; Isomoto, S; Kaibara, M; Konoe, A; Shimizu, A; Yano, K, 1995) |
| "Bepridil in combination with aprindine could restore sinus rhythm in patients with persistent atrial fibrillation (AF)." | 3.81 | Bepridil enhances aprindine-induced prolongation of atrial effective refractory period in a canine atrial rapid pacing model. ( Fujiki, A; Inoue, H; Kataoka, N; Mizumaki, K; Nakatani, Y; Nishida, K; Sakabe, M; Sakamoto, T; Yamaguchi, Y, 2015) |
| "The relationship between the efficacy of the anticholinergic action of disopyramide, cibenzoline and aprindine and age was examined in patients with paroxysmal and persistent atrial fibrillation." | 3.72 | [Comparison of the efficacies of disopyramide, cibenzoline and aprindine for the termination of paroxysmal and persistent atrial fibrillation in elderly and non-elderly patients]. ( Abe, N; Horiuchi, D; Kameda, K; Komatsu, T; Nakamura, S; Oikawa, K; Okumura, K; Owada, S; Suzuki, O; Tomita, H; Yomogida, K, 2003) |
| "In order to clarify the mechanisms by which the class Ib antiarrhythmic drug aprindine shows efficacy against atrial fibrillation (AF), we examined the effects of the drug on the repolarizing K+ currents in guinea-pig atrial cells by use of patch-clamp techniques." | 3.70 | Inhibitory effects of aprindine on the delayed rectifier K+ current and the muscarinic acetylcholine receptor-operated K+ current in guinea-pig atrial cells. ( Nakaya, H; Ohmoto-Sekine, Y; Tamagawa, M; Uemura, H, 1999) |
| "A 73-year-old man had been treated with Aprindine because of paroxysmal atrial fibrillation." | 3.68 | [A case of aprindine-induced pneumonitis]. ( Doutsu, Y; Hara, K; Hayashi, T; Hiratani, K; Hirota, M; Kohno, S; Komori, K; Miyazaki, T; Oda, H; Yamaguchi, K, 1990) |
| "Bepridil alone or in combination with aprindine converted long lasting persistent AF in association with an increase in both FCL and FOI." | 2.71 | Drug-induced changes in fibrillation cycle length and organization index can predict chemical cardioversion of long-lasting atrial fibrillation with bepridil alone or in combination with aprindine. ( Fujiki, A; Inoue, H; Iwamoto, J; Mizumaki, K; Nishida, K; Sakabe, M; Sugao, M; Tsuneda, T, 2004) |
| "The most important arrhythmia is ventricular tachycardia which degenerates to ventricular fibrillation." | 2.43 | [Strategy for cardiac arrhythmias in acute coronary syndrome]. ( Sugi, K, 2006) |
| "Flecainide-induced VF was antagonized by glibenclamide." | 1.29 | Antifibrillatory and profibrillatory actions of selected class I antiarrhythmic agents. ( Chi, L; Fagbemi, SO; Lucchesi, BR, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakatani, Y | 1 |
| Sakamoto, T | 3 |
| Nishida, K | 4 |
| Kataoka, N | 1 |
| Yamaguchi, Y | 1 |
| Sakabe, M | 3 |
| Fujiki, A | 6 |
| Mizumaki, K | 6 |
| Inoue, H | 7 |
| Shirayama, T | 1 |
| Shiraishi, H | 1 |
| Yoshida, S | 1 |
| Matoba, Y | 1 |
| Imai, H | 1 |
| Nakagawa, M | 1 |
| Komatsu, T | 1 |
| Nakamura, S | 1 |
| Suzuki, O | 1 |
| Yomogida, K | 1 |
| Horiuchi, D | 1 |
| Abe, N | 1 |
| Kameda, K | 1 |
| Owada, S | 1 |
| Tomita, H | 1 |
| Oikawa, K | 1 |
| Okumura, K | 1 |
| Tsuneda, T | 3 |
| Sugao, M | 2 |
| Nakagawa, K | 1 |
| Hirai, T | 1 |
| Iwamoto, J | 2 |
| Sugi, K | 2 |
| Nagasawa, H | 1 |
| Prystowsky, EN | 1 |
| Bauernfeind, RA | 1 |
| Swiryn, SP | 1 |
| Strasberg, B | 1 |
| Palileo, E | 1 |
| Scagliotti, D | 1 |
| Rosen, KM | 2 |
| Wang, HZ | 1 |
| Hano, O | 1 |
| Konoe, A | 1 |
| Hirata, T | 1 |
| Kaibara, M | 1 |
| Isomoto, S | 1 |
| Shimizu, A | 1 |
| Centurion, O | 1 |
| Hayano, M | 1 |
| Yano, K | 1 |
| Fagbemi, SO | 1 |
| Chi, L | 1 |
| Lucchesi, BR | 1 |
| Ohmoto-Sekine, Y | 1 |
| Uemura, H | 1 |
| Tamagawa, M | 1 |
| Nakaya, H | 1 |
| Atarashi, H | 1 |
| Fukunami, M | 1 |
| Hamada, C | 1 |
| Origasa, H | 1 |
| Zipes, DP | 1 |
| Gaum, WE | 1 |
| Foster, PR | 1 |
| Wu, D | 1 |
| Amat-Y-Leon, F | 1 |
| Noble, RJ | 1 |
| Oda, H | 1 |
| Doutsu, Y | 1 |
| Hiratani, K | 1 |
| Miyazaki, T | 1 |
| Komori, K | 1 |
| Hayashi, T | 1 |
| Kohno, S | 1 |
| Yamaguchi, K | 1 |
| Hirota, M | 1 |
| Hara, K | 1 |
2 reviews available for aprindine and Atrial Fibrillation
| Article | Year |
|---|---|
[Strategy for cardiac arrhythmias in acute coronary syndrome].
Topics: Amiodarone; Angina, Unstable; Anti-Asthmatic Agents; Aprindine; Atrial Fibrillation; Bepridil; Elect | 2006 |
Pharmacologic therapy of tachyarrhythmias in patients with Wolff-Parkinson-White syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Ajmaline; Amiodarone; Anilides; Aprindine; Atr | 1983 |
7 trials available for aprindine and Atrial Fibrillation
| Article | Year |
|---|---|
Usefulness and safety of bepridil in converting persistent atrial fibrillation to sinus rhythm.
Topics: Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Bepridil; Electrocardiography; Female; Heart | 2003 |
Maintenance of sinus rhythm and recovery of atrial mechanical function after cardioversion with bepridil or in combination with aprindine in long-lasting persistent atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Atrial Function; Bepridil; Disease-Free Surv | 2004 |
Drug-induced changes in fibrillation cycle length and organization index can predict chemical cardioversion of long-lasting atrial fibrillation with bepridil alone or in combination with aprindine.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Bepridil; Drug Therapy, Combination; E | 2004 |
Pharmacological cardioversion of persistent atrial fibrillation with and without a history of drug-resistant paroxysmal atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Bepridil; Drug Combinations; Drug Resistance | 2006 |
Relation of interleukin-6 and C-reactive protein levels to sinus maintenance after pharmacological cardioversion in persistent atrial fibrillation.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Bepridil; C-Reactive Protein; Drug The | 2007 |
Effects of aprindine on electrophysiological properties of the atrial muscle in man.
Topics: Action Potentials; Adult; Aged; Aprindine; Atrial Fibrillation; Electrocardiography; Electrophysiolo | 1995 |
Double-blind placebo-controlled trial of aprindine and digoxin for the prevention of symptomatic atrial fibrillation.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Coronary Disease; Diabetic Angiopathie | 2002 |
9 other studies available for aprindine and Atrial Fibrillation
| Article | Year |
|---|---|
Bepridil enhances aprindine-induced prolongation of atrial effective refractory period in a canine atrial rapid pacing model.
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Atrial Function; Atrial Remodeling; | 2015 |
Atrial fibrillation threshold predicted long-term efficacy of pharmacological treatment of patients without structural heart disease.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Disopyramide; Electrophysiologic Techn | 2002 |
[Comparison of the efficacies of disopyramide, cibenzoline and aprindine for the termination of paroxysmal and persistent atrial fibrillation in elderly and non-elderly patients].
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Autonomic Nervous System; Circadian Rh | 2003 |
Electrophysiologic drug testing in prophylaxis of sporadic paroxysmal atrial fibrillation: technique, application, and efficacy in severely symptomatic preexcitation patients.
Topics: Administration, Oral; Adolescent; Adult; Aprindine; Atrial Fibrillation; Cardiac Pacing, Artificial; | 1982 |
[The therapeutic effect of aprindine in treating 9 cases of Wolff-Parkinson-White syndrome associated with auricular fibrillation (author's transl)].
Topics: Adult; Aprindine; Atrial Fibrillation; Female; Humans; Indenes; Male; Middle Aged; Wolff-Parkinson-W | 1982 |
Antifibrillatory and profibrillatory actions of selected class I antiarrhythmic agents.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Blood Gas A | 1993 |
Inhibitory effects of aprindine on the delayed rectifier K+ current and the muscarinic acetylcholine receptor-operated K+ current in guinea-pig atrial cells.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Atrial Function; | 1999 |
Aprindine for treatment of supraventricular tachycardias. With particular application to Wolff-Parkinson-White syndrome.
Topics: Adult; Aprindine; Atrial Fibrillation; Atrial Flutter; Electrocardiography; Electrophysiology; Femal | 1977 |
[A case of aprindine-induced pneumonitis].
Topics: Aged; Aprindine; Atrial Fibrillation; Humans; Indenes; Male; Pneumonia | 1990 |