aprindine has been researched along with Arrhythmia in 82 studies
Aprindine: A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was performed to evaluate variability in the pharmacokinetics of bepridil in 38 Japanese patients with arrhythmias, and to investigate the effects of aprindine as well as CYP2D6 and CYP3A5 polymorphisms on the oral clearance of bepridil." | 9.12 | Nonlinear mixed effects model analysis of the pharmacokinetics of routinely administered bepridil in Japanese patients with arrhythmias. ( Fujiki, A; Hashimoto, Y; Horiuchi, I; Inoue, H; Iwamoto, J; Oshima, Y; Saigusa, K; Taguchi, M; Tahara, K, 2006) |
| "Five cases of aprindine-induced polymorphous ventricular tachycardia (torsade de pointes) are presented." | 9.05 | Aprindine-induced polymorphous ventricular tachycardia. ( Hai, HA; Kehoe, R; Rosen, K; Scagliotti, D; Strasberg, B, 1982) |
| "A placebo-controlled, randomized, double-blind, crossover study was performed in 14 patients with chronic, resistant, ventricular arrhythmias in order to evaluate the efficacy and safety of two new antiarrhythmic agents, propafenone and aprindine." | 9.05 | [Comparison of the anti-arrhythmic effects of propafenone and aprindine in the treatment of refractory chronic ventricular arrhythmias. A randomized double-blind crossover study controlled with placebo]. ( Amici, R; Ciampani, N; Costantini, C; Mocchegiani, R; Pigini, G; Purcaro, A, 1983) |
| "The incidence of ventricular arrhythmias after myocardial infarction was compared in a double blind study of disopyramide (33 patients), aprindine (34 patients) and placebo (31 patients)." | 9.04 | Effects of disopyramide and aprindine on arrhythmias after acute myocardial infarction. ( Chaudron, JM; Pouleur, H; Reyns, P, 1977) |
| " Arrhythmias produced by ouabain were converted to sinus rhythm by indecainide (100 micrograms/kg/min, i." | 7.67 | Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. ( Gonzales, CR; Holland, DR; Johnston, SR; Lacefield, WB; Turk, JA, 1989) |
| "Aprindine hydrochloride was administered IV and orally to 20 dogs with ventricular tachycardia." | 7.66 | Aprindine for treatment of ventricular arrhythmias in the dog. ( Bonagura, JD; Muir, WW, 1982) |
| "Moxaprindine, a new anti-arrhythmic drug, with characteristics similar to aprindine, has been demonstrated to be highly effective in suppressing ventricular arrhythmias occurring before, during and after maximal exercise stress testing." | 7.66 | Influence of moxaprindine treatment on ventricular arrhythmias occurring during maximal exercise stress testing. ( Kesteloot, H; Marchandise, B; Sluyts, R; van de Werf, F, 1979) |
| "Aprindine is a very effective antiarrhythmic agent with a narrow therapeutic ratio." | 5.28 | Aprindine-induced hepatic granulomata. ( Elisaf, M; Masalas, C; Stefanaki-Nikou, S; Tsianos, EV; Voulgarelis, M, 1992) |
| " The sinus rate was slowed at every dosage level." | 5.26 | Moxaprindine in the acute treatment of ventricular arrhythmias in patients with cardiovascular disease. ( Kesteloot, H; Staessen, J, 1981) |
| "Aprindine hydrochloride is an antiarrhythmic drug now under investigation." | 5.26 | Agranulocytosis associated with aprindine therapy. ( Bodenheimer, HC; Samarel, AM, 1979) |
| "This study was performed to evaluate variability in the pharmacokinetics of bepridil in 38 Japanese patients with arrhythmias, and to investigate the effects of aprindine as well as CYP2D6 and CYP3A5 polymorphisms on the oral clearance of bepridil." | 5.12 | Nonlinear mixed effects model analysis of the pharmacokinetics of routinely administered bepridil in Japanese patients with arrhythmias. ( Fujiki, A; Hashimoto, Y; Horiuchi, I; Inoue, H; Iwamoto, J; Oshima, Y; Saigusa, K; Taguchi, M; Tahara, K, 2006) |
| "Aprindine was administered for 12 months to 8 hemodialysis patients suffering from arrhythmias." | 5.08 | Chronic administration of aprindine during maintenance hemodialysis. ( Hirota, Y; Nakamura, S; Takata, Y; Tsuchihashi, T, 1997) |
| "Five cases of aprindine-induced polymorphous ventricular tachycardia (torsade de pointes) are presented." | 5.05 | Aprindine-induced polymorphous ventricular tachycardia. ( Hai, HA; Kehoe, R; Rosen, K; Scagliotti, D; Strasberg, B, 1982) |
| "A placebo-controlled, randomized, double-blind, crossover study was performed in 14 patients with chronic, resistant, ventricular arrhythmias in order to evaluate the efficacy and safety of two new antiarrhythmic agents, propafenone and aprindine." | 5.05 | [Comparison of the anti-arrhythmic effects of propafenone and aprindine in the treatment of refractory chronic ventricular arrhythmias. A randomized double-blind crossover study controlled with placebo]. ( Amici, R; Ciampani, N; Costantini, C; Mocchegiani, R; Pigini, G; Purcaro, A, 1983) |
| "Oral long-term treatment with various antiarrhythmic drugs (aprindine, mexiletine, disopyramide, amiodarone) was assessed in 82 patients with recurrent tachycardias demonstrated in the ECG using programmed ventricular stimulation." | 5.05 | [Long-term drug therapy in ventricular cardiac arrhythmias. Is an improvement of the prognosis possible?]. ( Lüderitz, B; Manz, M; Steinbeck, G, 1983) |
| "The incidence of ventricular arrhythmias after myocardial infarction was compared in a double blind study of disopyramide (33 patients), aprindine (34 patients) and placebo (31 patients)." | 5.04 | Effects of disopyramide and aprindine on arrhythmias after acute myocardial infarction. ( Chaudron, JM; Pouleur, H; Reyns, P, 1977) |
| "Aprindine is a long-acting antiarrhythmic agent, effective when administered orally or intravenously in the treatment of ventricular arrhythmias of varying etiologies." | 4.76 | Aprindine. ( Danilo, P, 1979) |
| "The effects of long-term aprindine administration on cardiac function were clinically investigated in seven patients with supraventricular or ventricular arrhythmias associated with organic heart disease." | 3.67 | Long-term oral antiarrhythmic therapy with aprindine: effects on cardiac function and adverse effects. ( Araki, H; Nagata, Y; Nakamura, M; Tsutsui, H, 1984) |
| " Arrhythmias produced by ouabain were converted to sinus rhythm by indecainide (100 micrograms/kg/min, i." | 3.67 | Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. ( Gonzales, CR; Holland, DR; Johnston, SR; Lacefield, WB; Turk, JA, 1989) |
| "The efficacy of disopyramide (DP), mexiletine (MX), aprindine (AP) and cibenzoline (CZ) on ventricular arrhythmias was compared (single drug therapy)." | 3.67 | Therapeutic effectiveness and plasma levels of single or combination use of class I antiarrhythmic agents for ventricular arrhythmias. ( Furuya, H; Goto, Y; Tanabe, T; Yoshikawa, H, 1988) |
| "In 36 patients with cardiac arrhythmias (predominantly ventricular premature beats), who were on oral aprindine long-term therapy with 50 to 400 mg daily, plasma levels were measured by gas chromatography after 3." | 3.66 | [Detection of aprindine and its metabolites in plasma and urine]. ( Breithardt, G; Michaelis, L; Wirth, KE, 1983) |
| "Aprindine hydrochloride was administered IV and orally to 20 dogs with ventricular tachycardia." | 3.66 | Aprindine for treatment of ventricular arrhythmias in the dog. ( Bonagura, JD; Muir, WW, 1982) |
| "Moxaprindine, a new anti-arrhythmic drug, with characteristics similar to aprindine, has been demonstrated to be highly effective in suppressing ventricular arrhythmias occurring before, during and after maximal exercise stress testing." | 3.66 | Influence of moxaprindine treatment on ventricular arrhythmias occurring during maximal exercise stress testing. ( Kesteloot, H; Marchandise, B; Sluyts, R; van de Werf, F, 1979) |
| "Ventricular arrhythmias due to myocardial infarct were produced in 14 dogs, and the antiarrhytmic effects of quinidine (Qd), lidocaine (Lid), aprindine (Apr), and dl-propranolol (dl-Prop) were investigated." | 3.66 | [Effects of antiarrhythmic agents on ventricular arrhythmias following myocardial infarct induced with glass beads in dogs (author's transl)]. ( Haruna, M; Kimoto, S; Nakao, T; Ueda, M, 1981) |
| "Cardiac effects of aprindine, a relatively new antiarrhythmic agent, were investigated by means of echocardiography in nine patients with ventricular arrhythmias." | 3.66 | Cardiac effects of aprindine in patients with or without cardiac dysfunction: echocardiographic and clinical evaluation. ( Araki, H; Nakagaki, O; Nakamura, M; Orita, Y; Shimada, R, 1983) |
| "The clinical efficacy of Aprindine, a new antiarrhythmic agent was tested in 37 patients with ventricular and supraventricular arrhythmias." | 3.66 | Evaluation of clinical efficacy and plasma levels of aprindine. ( Ambrosioni, E; Bracchetti, D; Magnani, B; Malini, PL, 1979) |
| "The acute electrophysiologic effects of intravenous aprindine were evaluated in 48 patients to assess the effect on conduction times and refractoriness in patients with severe cardiac disease and arrhythmias." | 3.66 | Prolongation of cardiac conduction times by intravenous aprindine in man. ( Greene, HL; Reid, PR; Schaeffer, AH, 1978) |
| "The object of this study was to compare the efficacity and the side effects of Aprindine and Quinidine in patients with stable ventricular arrhythmias." | 3.66 | [Comparison of the efficacy of aprindine and quinidine in chronic ventricular rhythm disorders]. ( Attuel, P; Coumel, P; Leclercq, JF; Milosevic, D; Rosengarten, MD, 1981) |
| "The effectiveness of aprindine, N-[3-(diethyl amino)propyl]-N-phenyl-2-indanamine, was examined against experimentally induced arrhythmias." | 3.65 | Antiarrhythmic and antifibrillatory properties of aprindine. ( Kroll, DA; Lucchesi, BR, 1975) |
| "The effect of intravenously administered aprindine (AC1802) as a prophylactic agent against ventricular arrhythmias was studied in pigs." | 3.65 | Cardiovascular and antiarrhythmic effects of aprindine (AC1802) during partial occlusion of a coronary artery in the pig. ( Hugenholtz, PG; Remme, WJ; Verdouw, PD, 1977) |
| "Aprindine was chosen because of its long half-life, few side effects, and antiarrhythmic efficacy." | 2.66 | Prophylactic antiarrhythmic therapy of high-risk survivors of myocardial infarction: lower mortality at 1 month but not at 1 year. ( Achuff, SC; Baughman, KL; Becker, L; Chandra, NC; Gerstenblith, G; Gottlieb, SH; Heck, C; Henley, S; Humphries, JO; Mellits, ED, 1987) |
| "Many sudden deaths are presumed to be due to an arrhythmia, but the drugs best known for antiarrhythmic activity, the local anesthetic agents, have not been suitable prophylactic agents because of their toxicities and other undesirable pharmacologic characteristics." | 2.65 | Selection of an antiarrhythmic drug for a sudden-death-prevention trial. ( Duff, HJ; Oates, JA; Roden, DM; Woosley, RL, 1982) |
| " Serious adverse reactions necessitate a change in antiarrhythmic therapy, as opposed to lowering drug dosage to an ineffective level." | 2.37 | Antiarrhythmic drug therapy. Recent advances and current status. ( Somberg, J, 1985) |
| "Aprindine is a very effective antiarrhythmic agent with a narrow therapeutic-toxic ratio." | 2.36 | Studies with aprindine. ( Elharrar, V; Gilmour, RF; Heger, JJ; Prystowsky, EN; Zipes, DP, 1980) |
| "Cardiac arrhythmias may be caused by abnormalities of impulse initiation, impulse propagation, or a combination of the two." | 2.36 | Electropharmacology of antiarrhythmic drugs. ( Rosen, MR; Wit, AL, 1983) |
| "Aprindine is a very effective antiarrhythmic agent with a narrow therapeutic ratio." | 1.28 | Aprindine-induced hepatic granulomata. ( Elisaf, M; Masalas, C; Stefanaki-Nikou, S; Tsianos, EV; Voulgarelis, M, 1992) |
| "Treatment with aprindine or mexiletine was effective in 7 (50%) of the 14 patients who did not respond to procainamide and/or disopyramide." | 1.28 | Analysis of ventricular arrhythmias in patients with dilated cardiomyopathy--relationship between the effects of antiarrhythmic agents and severity of myocardial lesions. ( Fukuzaki, H; Takarada, A; Yokota, Y, 1990) |
| "The presence of a left bundle branch block (LBBB) may hamper the electrocardiographic diagnosis of diseases that involve the QRS complexes." | 1.28 | [Drug-induced major anomalies of ventricular repolarization masked by a left branch block]. ( Dujardin, JJ; Haiat, R; Joly, P; Kacet, S; Nicolai, P, 1989) |
| "Aprindine hydrochloride is an antiarrhythmic agent presently undergoing clinical trials in the United States." | 1.27 | Long-term follow-up of patients receiving aprindine. Safety and efficacy. ( Bauernfeind, R; Bauman, J; Coelho, A; Prechel, D; Rosen, KM; Strasberg, B; Swiryn, S, 1983) |
| "Phenytoin was effective on three arrhythmias and its min PCs were 9." | 1.27 | Quantitative analysis of the antiarrhythmic effect of drugs on canine ventricular arrhythmias by the determination of minimum effective plasma concentrations. ( Hashimoto, K; Imai, S; Satoh, H; Shibuya, T, 1983) |
| "After treatment of ischemia and/or failure, specific antiarrhythmic agents, conventional and investigational, alone or in combination, are systematically selected." | 1.26 | Ventricular ectopy: etiology, evaluation, and therapy. ( Reid, PR; Vlay, SC, 1982) |
| " The sinus rate was slowed at every dosage level." | 1.26 | Moxaprindine in the acute treatment of ventricular arrhythmias in patients with cardiovascular disease. ( Kesteloot, H; Staessen, J, 1981) |
| "Moxaprindine is a powerful antiarrhythmic agent which deserves further assessment in long term studies." | 1.26 | The efficacy of intravenous moxaprindine on ventricular ectopic activity. ( Guillaume, D; Kulbertus, H; Mary-Rabine, L; Waleffe, A, 1980) |
| "Aprindine hydrochloride is an antiarrhythmic drug now under investigation." | 1.26 | Agranulocytosis associated with aprindine therapy. ( Bodenheimer, HC; Samarel, AM, 1979) |
| "The incidence of ventricular arrhythmias was increased by aprindine (from 1 in 11 to 8 in 11 dogs), decresed by verapamil (from 3 in 7 to 0 in 7 dogs) and was not changes by quinidine or isoproterenol." | 1.26 | Effect of drugs on conduction delay and incidence of ventricular arrhythmias induced by acute coronary occlusion in dogs. ( Elharrar, V; Gaum, WE; Zipes, DP, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 74 (90.24) | 18.7374 |
| 1990's | 6 (7.32) | 18.2507 |
| 2000's | 2 (2.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nogami, Y | 1 |
| Takase, B | 1 |
| Matsui, T | 1 |
| Hattori, H | 1 |
| Hamabe, A | 1 |
| Fujita, M | 1 |
| Ohsuzu, F | 1 |
| Ishihara, M | 1 |
| Maekara, T | 1 |
| Taguchi, M | 1 |
| Fujiki, A | 1 |
| Iwamoto, J | 1 |
| Inoue, H | 1 |
| Tahara, K | 1 |
| Saigusa, K | 1 |
| Horiuchi, I | 1 |
| Oshima, Y | 1 |
| Hashimoto, Y | 1 |
| Sanna, GP | 1 |
| Opie, LH | 2 |
| Vlay, SC | 1 |
| Reid, PR | 4 |
| Woosley, RL | 1 |
| Roden, DM | 1 |
| Duff, HJ | 1 |
| Oates, JA | 1 |
| Lüderitz, B | 3 |
| Zipes, DP | 9 |
| Elharrar, V | 2 |
| Gilmour, RF | 1 |
| Heger, JJ | 4 |
| Prystowsky, EN | 4 |
| Purcaro, A | 1 |
| Amici, R | 1 |
| Ciampani, N | 1 |
| Costantini, C | 1 |
| Mocchegiani, R | 1 |
| Pigini, G | 1 |
| Rosen, MR | 2 |
| Wit, AL | 1 |
| Manz, M | 2 |
| Steinbeck, G | 2 |
| Pratt, CM | 1 |
| Luck, JC | 1 |
| Mann, DE | 1 |
| Wyndham, CR | 1 |
| Tsutsui, H | 1 |
| Araki, H | 2 |
| Nagata, Y | 1 |
| Nakamura, M | 2 |
| Strasberg, B | 2 |
| Prechel, D | 1 |
| Bauman, J | 1 |
| Coelho, A | 1 |
| Swiryn, S | 1 |
| Bauernfeind, R | 1 |
| Rosen, KM | 1 |
| Wirth, KE | 1 |
| Breithardt, G | 1 |
| Michaelis, L | 1 |
| Ikeda, T | 1 |
| Kubota, K | 1 |
| Higashino, A | 1 |
| Hattori, N | 1 |
| Benchimol, A | 1 |
| Desser, KB | 1 |
| Singh, BN | 2 |
| Cho, YW | 1 |
| Kuemmerle, HP | 1 |
| Leclercq, JF | 1 |
| Attuel, P | 1 |
| Milosevic, D | 1 |
| Rosengarten, MD | 1 |
| Coumel, P | 2 |
| Nademanee, K | 1 |
| Keefe, DL | 1 |
| Kates, RE | 1 |
| Harrison, DC | 2 |
| Hashimoto, K | 1 |
| Shibuya, T | 1 |
| Satoh, H | 1 |
| Imai, S | 1 |
| Shimada, R | 1 |
| Orita, Y | 1 |
| Nakagaki, O | 1 |
| Zeng, GY | 1 |
| Waleffe, A | 1 |
| Guillaume, D | 1 |
| Mary-Rabine, L | 1 |
| Kulbertus, H | 1 |
| Winkle, RA | 2 |
| Stoel, I | 1 |
| Hagemeijer, F | 1 |
| Scagliotti, D | 1 |
| Hai, HA | 1 |
| Kehoe, R | 1 |
| Rosen, K | 1 |
| Alves, LE | 1 |
| Rose, EP | 1 |
| Mueller, HS | 1 |
| Muir, WW | 1 |
| Bonagura, JD | 1 |
| Staessen, J | 1 |
| Kesteloot, H | 3 |
| Nattel, S | 1 |
| Pedersen, DH | 1 |
| Fang, WH | 1 |
| Kimoto, S | 1 |
| Haruna, M | 1 |
| Nakao, T | 1 |
| Ueda, M | 1 |
| Pantlen, H | 1 |
| Runge, M | 1 |
| Luckmann, E | 1 |
| Jacobs, GP | 1 |
| Pores, IH | 1 |
| Takanaka, C | 1 |
| Lee, JK | 1 |
| Nonokawa, M | 1 |
| Sugiyama, T | 1 |
| Yame, S | 1 |
| Ogawa, S | 1 |
| Mitamura, H | 1 |
| Katoh, H | 1 |
| Takata, Y | 1 |
| Tsuchihashi, T | 1 |
| Nakamura, S | 1 |
| Hirota, Y | 1 |
| van Leeuwen, R | 1 |
| Meyboom, RH | 1 |
| Borger, HH | 1 |
| Krikler, D | 1 |
| Wellens, HJ | 1 |
| van de Werf, F | 1 |
| Marchandise, B | 1 |
| Sluyts, R | 1 |
| Pouleur, H | 1 |
| Chaudron, JM | 1 |
| Reyns, P | 1 |
| Pozenel, H | 1 |
| Danilo, P | 1 |
| Baedeker, W | 1 |
| Rastetter, J | 1 |
| Check, WA | 1 |
| Bodenheimer, HC | 1 |
| Samarel, AM | 1 |
| Malini, PL | 1 |
| Ambrosioni, E | 1 |
| Bracchetti, D | 1 |
| Magnani, B | 1 |
| De Clerck, F | 1 |
| Van Gorp, L | 1 |
| Xhonneux, R | 1 |
| Anderson, JL | 1 |
| Meffin, PJ | 1 |
| Wei, JY | 1 |
| Bulkley, BH | 1 |
| Schaeffer, AH | 2 |
| Greene, HL | 2 |
| Herlong, HF | 1 |
| Boitnott, JK | 1 |
| Maddrey, WC | 1 |
| Troup, PJ | 1 |
| Ferrero Cabedo, JA | 1 |
| Insa Pérez, LD | 1 |
| López Merino, V | 1 |
| Botella Solana, S | 1 |
| Brugger Auban, A | 1 |
| Esplugues Requena, J | 1 |
| Gaum, WE | 1 |
| Verdouw, PD | 1 |
| Remme, WJ | 1 |
| Hugenholtz, PG | 1 |
| Hausamen, TU | 1 |
| Weber, FW | 1 |
| Kroll, DA | 1 |
| Lucchesi, BR | 1 |
| Villalobos Galán, E | 1 |
| Martin Santos, F | 1 |
| Fernández Corral, E | 1 |
| de Elio Membrado, FJ | 1 |
| Steinbach, K | 1 |
| Elisaf, M | 1 |
| Stefanaki-Nikou, S | 1 |
| Voulgarelis, M | 1 |
| Masalas, C | 1 |
| Tsianos, EV | 1 |
| Suzuki, M | 1 |
| Takarada, A | 1 |
| Yokota, Y | 1 |
| Fukuzaki, H | 1 |
| Podrid, PJ | 2 |
| Holland, DR | 1 |
| Lacefield, WB | 1 |
| Gonzales, CR | 1 |
| Johnston, SR | 1 |
| Turk, JA | 1 |
| Haiat, R | 1 |
| Nicolai, P | 1 |
| Dujardin, JJ | 1 |
| Joly, P | 1 |
| Kacet, S | 1 |
| Tanabe, T | 2 |
| Yoshikawa, H | 2 |
| Tagawa, R | 1 |
| Furuya, H | 2 |
| Ide, M | 1 |
| Goto, Y | 2 |
| Somberg, J | 1 |
| Gottlieb, SH | 1 |
| Achuff, SC | 1 |
| Mellits, ED | 1 |
| Gerstenblith, G | 1 |
| Baughman, KL | 1 |
| Becker, L | 1 |
| Chandra, NC | 1 |
| Henley, S | 1 |
| Humphries, JO | 1 |
| Heck, C | 1 |
| Kikuchi, H | 1 |
| Honda, T | 1 |
| Kugimiya, H | 1 |
| Matuda, H | 1 |
| Matunaga, T | 1 |
| Takemiya, S | 1 |
| Hayasaki, K | 1 |
10 reviews available for aprindine and Arrhythmia
| Article | Year |
|---|---|
Studies with aprindine.
Topics: Agranulocytosis; Animals; Aprindine; Arrhythmias, Cardiac; Cholestasis; Dogs; Electrophysiology; Hum | 1980 |
Electropharmacology of antiarrhythmic drugs.
Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide | 1983 |
Electrophysiology and pharmacology of aprindine, encainide, and propafenone.
Topics: Action Potentials; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Elect | 1984 |
Investigational antiarrhythmic drugs for the treatment of ventricular rhythm disturbances.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Encainide; Flecainide | 1984 |
New antiarrhythmic drugs: their place in therapy.
Topics: Action Potentials; Ajmaline; Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhy | 1981 |
Aprindine: a review.
Topics: Administration, Oral; Agranulocytosis; Animals; Aprindine; Arrhythmias, Cardiac; Chemical and Drug I | 1980 |
[Significance and therapy of extrasystole].
Topics: Aprindine; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiac Output; Heart Ventricles; Hum | 1977 |
Aprindine.
Topics: Administration, Oral; Agranulocytosis; Animals; Aprindine; Arrhythmias, Cardiac; Autonomic Nervous S | 1979 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple | 1985 |
Antiarrhythmic drug therapy. Recent advances and current status.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrh | 1985 |
10 trials available for aprindine and Arrhythmia
| Article | Year |
|---|---|
Nonlinear mixed effects model analysis of the pharmacokinetics of routinely administered bepridil in Japanese patients with arrhythmias.
Topics: Adult; Aged; Algorithms; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bepridil; Cytochro | 2006 |
Selection of an antiarrhythmic drug for a sudden-death-prevention trial.
Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneac | 1982 |
[Comparison of the anti-arrhythmic effects of propafenone and aprindine in the treatment of refractory chronic ventricular arrhythmias. A randomized double-blind crossover study controlled with placebo].
Topics: Adult; Aged; Aprindine; Arrhythmias, Cardiac; Chronic Disease; Clinical Trials as Topic; Double-Blin | 1983 |
[Long-term drug therapy in ventricular cardiac arrhythmias. Is an improvement of the prognosis possible?].
Topics: Adult; Aged; Amiodarone; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; Long-Term Care; Mexi | 1983 |
Aprindine-induced polymorphous ventricular tachycardia.
Topics: Aged; Aprindine; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrocardiography; Female; Humans | 1982 |
Chronic administration of aprindine during maintenance hemodialysis.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Electrocardiography; | 1997 |
Effects of disopyramide and aprindine on arrhythmias after acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Aprindine; Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; | 1977 |
[The effect of mexiletine, ajmaline and aprindine on ventricular arrhythmias].
Topics: Aged; Ajmaline; Aprindine; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrocardiography; Fema | 1978 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple | 1985 |
Prophylactic antiarrhythmic therapy of high-risk survivors of myocardial infarction: lower mortality at 1 month but not at 1 year.
Topics: Aprindine; Arrhythmias, Cardiac; Capsules; Clinical Trials as Topic; Death, Sudden; Double-Blind Met | 1987 |
63 other studies available for aprindine and Arrhythmia
| Article | Year |
|---|---|
Effect of antiarrhythmic agents on heart rate variability indices after myocardial infarction: comparative experimental study of aprindine and procainamide.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Atrop | 2005 |
New drugs in the management of ventricular arrhythmias.
Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneac | 1984 |
Drugs and the heart. IV. Antiarrhythmic agents.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Br | 1980 |
Aprindine and agranulocytosis.
Topics: Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Bone Marrow; Humans; Indenes | 1980 |
Ventricular ectopy: etiology, evaluation, and therapy.
Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Aprindine; Arrhyth | 1982 |
[Drug therapy of arrhythmia in coronary cardiopathy].
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Comp | 1983 |
Drug therapy of cardiac arrhythmias.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Biological Availabili | 1983 |
Long-term oral antiarrhythmic therapy with aprindine: effects on cardiac function and adverse effects.
Topics: Administration, Oral; Adolescent; Aged; Aprindine; Arrhythmias, Cardiac; Drug Evaluation; Female; He | 1984 |
Long-term follow-up of patients receiving aprindine. Safety and efficacy.
Topics: Adolescent; Adult; Aged; Aprindine; Arrhythmias, Cardiac; Drug Evaluation; Female; Follow-Up Studies | 1983 |
[Detection of aprindine and its metabolites in plasma and urine].
Topics: Aprindine; Arrhythmias, Cardiac; Chemical Phenomena; Chemistry; Chromatography, Gas; Humans; Indenes | 1983 |
[Ventricular heart-rhythm disorders - sudden cardiac death: results of long-term drug therapy].
Topics: Adult; Aged; Aprindine; Arrhythmias, Cardiac; Coronary Disease; Female; Germany, West; Humans; Inden | 1983 |
[Aprindine, an anti-arrhythmia agent for arrhythmia associated with myocardial infarct].
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Dogs; Heart Conduction System; Humans; Indenes; Myocardial | 1983 |
New drugs for treating cardiac arrhythmias.
Topics: Acebutolol; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Encainide | 1981 |
Clinical pharmacology of antiarrhythmic drugs: a review and overview, part II.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; | 1981 |
[Comparison of the efficacy of aprindine and quinidine in chronic ventricular rhythm disorders].
Topics: Aprindine; Arrhythmias, Cardiac; Chronic Disease; Heart Ventricles; Humans; Indenes; Quinidine | 1981 |
Advances in antiarrhythmic therapy. The role of newer antiarrhythmic drugs.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Atrioventricular Node; Humans; | 1982 |
Electrophysiologic testing of antiarrhythmic agents.
Topics: Administration, Oral; Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, | 1982 |
Quantitative analysis of the antiarrhythmic effect of drugs on canine ventricular arrhythmias by the determination of minimum effective plasma concentrations.
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Dogs; Female; Lidoca | 1983 |
Cardiac effects of aprindine in patients with or without cardiac dysfunction: echocardiographic and clinical evaluation.
Topics: Adolescent; Adult; Aprindine; Arrhythmias, Cardiac; Echocardiography; Female; Heart; Humans; Indenes | 1983 |
[Clinical pharmacology of anti-arrhythmia agents].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Humans; Lidocaine; Qui | 1983 |
The efficacy of intravenous moxaprindine on ventricular ectopic activity.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Child; Electrocardiography; Fe | 1980 |
Clinical efficacy of antiarrhythmic drugs in prevention of sudden coronary death.
Topics: Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Angiography; Coronary Artery Bypas | 1982 |
Aprindine in the treatment of the idiopathic QT interval prolongation syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Digoxin; Drug Therapy, Combination; | 1982 |
Aprindine for treatment of ventricular arrhythmias in the dog.
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Dog Diseases; Dogs; Female; Heart; Heart Ventricles; Hemod | 1982 |
Moxaprindine in the acute treatment of ventricular arrhythmias in patients with cardiovascular disease.
Topics: Adult; Aprindine; Arrhythmias, Cardiac; Drug Evaluation; Electrocardiography; Heart Rate; Heart Vent | 1981 |
Alterations in regional myocardial distribution and arrhythmogenic effects of aprindine produced by coronary artery occlusion in the dog.
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Dogs; Female; Hear | 1981 |
[Aprindine for intractable dysarrhythmia (author's transl)].
Topics: Adolescent; Adult; Aprindine; Arrhythmias, Cardiac; Female; Humans; Indenes; Male; Middle Aged | 1980 |
[Effects of antiarrhythmic agents on ventricular arrhythmias following myocardial infarct induced with glass beads in dogs (author's transl)].
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, | 1981 |
[Effect of aprindine in patients with normal and pre-damaged impulse forming and excitation conducting system. Second communication: Conduction times (author's transl)].
Topics: Aprindine; Arrhythmias, Cardiac; Atrioventricular Node; Electric Stimulation; Electrocardiography; F | 1980 |
Aprindine psychosis.
Topics: Adult; Aprindine; Arrhythmias, Cardiac; Female; Humans; Indenes; Psychoses, Substance-Induced | 1980 |
New approaches to antiarrhythmic therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Heart Conduction System; Humans | 1981 |
Frequency dependent effects of class I antiarrhythmic agents studied in patients with implanted pacemakers.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cross-Ove | 1994 |
Effect of E-4031, a new class III antiarrhythmic drug, on reentrant ventricular arrhythmias: comparison with conventional class I drugs.
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disease Models, Animal; Disopyrami | 1993 |
Agranulocytosis and aprindine.
Topics: Adult; Aged; Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Female; Humans; Indenes; Male; Middle | 1976 |
Newer antiarrhythmic drugs.
Topics: Administration, Oral; Adult; Amiodarone; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Ca | 1978 |
Influence of moxaprindine treatment on ventricular arrhythmias occurring during maximal exercise stress testing.
Topics: Adult; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Exercise Test; Humans; Indenes; Male | 1979 |
[Agranulocytosis after treatment with apridine].
Topics: Aged; Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Female; Humans; Indenes | 1977 |
Arrhythmia indicators.
Topics: Aprindine; Arrhythmias, Cardiac; Electrocardiography; Humans; Indenes; Myocardial Infarction | 1979 |
Agranulocytosis associated with aprindine therapy.
Topics: Aged; Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Humans; Indenes; Male | 1979 |
Evaluation of clinical efficacy and plasma levels of aprindine.
Topics: Adult; Aged; Aprindine; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Indenes; Male; Mi | 1979 |
Effect of lorcainide, a new antiarrhythmic compound, on the changes in heart rhythm induced by intravenous injection of adenosine-5'-diphosphate in rats.
Topics: Acetamides; Adenosine Diphosphate; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; | 1978 |
Antiarrhythmic drugs: clinical pharmacology and therapeutic uses.
Topics: Acebutolol; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds | 1978 |
Mitral-valve prolapse syndrome and recurrent ventricular tachyarrhythmias: a malignant variant refractory to conventional drug therapy.
Topics: Adult; Aged; Aprindine; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Male; Middle Aged | 1978 |
Aprindine hepatitis.
Topics: Aprindine; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Female; Humans; Indenes; Li | 1978 |
New antiarrhythmic drugs.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Humans; Lidocaine; Mexiletine; | 1978 |
Prolongation of cardiac conduction times by intravenous aprindine in man.
Topics: Adult; Aged; Aprindine; Arrhythmias, Cardiac; Atrioventricular Node; Bundle of His; Cardiac Pacing, | 1978 |
Electrophysiological effects of aprindine on A-V conduction in the dog.
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Bundle of His; Dogs; Electric Stimulation; Electrocardiogr | 1978 |
Effect of drugs on conduction delay and incidence of ventricular arrhythmias induced by acute coronary occlusion in dogs.
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Coronary Disease; Disease Models, Animal; Dogs; Heart Cond | 1977 |
Cardiovascular and antiarrhythmic effects of aprindine (AC1802) during partial occlusion of a coronary artery in the pig.
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Carbon Dioxide; Coronary Disease; Indenes; Swine; Ventricu | 1977 |
[Fatal course of agranulocytosis during antiarryhthmic aprindine therapy].
Topics: Aged; Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Female; Humans; Indenes | 1977 |
Aprindine.
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Dogs; Indenes; Ouabain | 1976 |
Antiarrhythmic and antifibrillatory properties of aprindine.
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Coronary Vessels; Dogs; Electrocardiography; Female; Inden | 1975 |
[Clinical evaluation of a new drug (Aprindine) on ventricular and superventricular arrhythmia].
Topics: Administration, Oral; Aprindine; Arrhythmias, Cardiac; Drug Evaluation; Heart Ventricles; Humans; In | 1975 |
[Treatment of arrhythmia in general practice].
Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; H | 1975 |
Aprindine-induced hepatic granulomata.
Topics: Aprindine; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Female; Fibrosis; Granuloma | 1992 |
[Therapeutic drug monitoring of disopyramide, mexiletine, aprindine and beta blockers].
Topics: Adrenergic beta-Antagonists; Aprindine; Arrhythmias, Cardiac; Biological Availability; Chromatograph | 1990 |
Analysis of ventricular arrhythmias in patients with dilated cardiomyopathy--relationship between the effects of antiarrhythmic agents and severity of myocardial lesions.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Disop | 1990 |
Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics.
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bundle of Hi | 1989 |
[Drug-induced major anomalies of ventricular repolarization masked by a left branch block].
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Beprid | 1989 |
Evaluation of antiarrhythmic drug efficacy using holter electrocardiographic technique.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Complexes, | 1985 |
Therapeutic effectiveness and plasma levels of single or combination use of class I antiarrhythmic agents for ventricular arrhythmias.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Chronic Disease; Disopyramide; | 1988 |
Aggravation of ventricular arrhythmia. A drug-induced complication.
Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; El | 1985 |
[Clinical efficacy and plasma levels of oral aprindine, a new antiarrhythmic drug].
Topics: Administration, Oral; Adult; Aged; Aprindine; Arrhythmias, Cardiac; Drug Evaluation; Female; Half-Li | 1985 |