aprindine has been researched along with Agranulocytosis in 17 studies
Aprindine: A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The in vitro bone marrow growth of 2 patients with aprindine-induced agranulocytosis was studied." | 7.67 | Mechanism of aprindine induced agranulocytosis: direct toxicity on CFU-C and CFU-GEMM. ( Boogaerts, MA; Kesteloot, H; Peersman, C; Peters, M; Verwilghen, RL, 1984) |
| "Clinical use of aprindine hydrochloride is occasionally complicated by agranulocytosis." | 7.66 | Aprindine-induced agranulocytosis. Evidence for immunologic mechanism. ( Cronkite, C; Pisciotta, AV, 1983) |
| "The risk of agranulocytosis associated with anti-arrhythmic drugs has been assessed by studying previous drug exposure of all cases collected through a multicentre surveillance network in a defined geographical area during the period 1980-1988." | 6.38 | Agranulocytosis associated with aprindine and other antiarrhythmic drugs: an epidemiological approach. ( Carné, X; Ibáñez, L; Juan, J; Laporte, JR; Pérez, E, 1991) |
| "Aprindine was effective in five cases, and it failed in two." | 5.27 | Aprindine therapy for refractory ventricular tachycardia. ( Carleton, RA; Chown, M; Khan, AH, 1983) |
| "Aprindine hydrochloride is an antiarrhythmic drug now under investigation." | 5.26 | Agranulocytosis associated with aprindine therapy. ( Bodenheimer, HC; Samarel, AM, 1979) |
| "Aprindine is a long-acting antiarrhythmic agent, effective when administered orally or intravenously in the treatment of ventricular arrhythmias of varying etiologies." | 4.76 | Aprindine. ( Danilo, P, 1979) |
| "Clinical use of aprindine hydrochloride is occasionally complicated by agranulocytosis." | 3.66 | Aprindine-induced agranulocytosis. Evidence for immunologic mechanism. ( Cronkite, C; Pisciotta, AV, 1983) |
| "Aprindine is a very effective antiarrhythmic agent with a narrow therapeutic-toxic ratio." | 2.36 | Studies with aprindine. ( Elharrar, V; Gilmour, RF; Heger, JJ; Prystowsky, EN; Zipes, DP, 1980) |
| "Aprindine was effective in five cases, and it failed in two." | 1.27 | Aprindine therapy for refractory ventricular tachycardia. ( Carleton, RA; Chown, M; Khan, AH, 1983) |
| "Aprindine hydrochloride is an antiarrhythmic drug now under investigation." | 1.26 | Agranulocytosis associated with aprindine therapy. ( Bodenheimer, HC; Samarel, AM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (94.12) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Opie, LH | 1 |
| Zipes, DP | 1 |
| Elharrar, V | 1 |
| Gilmour, RF | 1 |
| Heger, JJ | 1 |
| Prystowsky, EN | 1 |
| Pisciotta, AV | 1 |
| Cronkite, C | 1 |
| Boogaerts, MA | 1 |
| Peters, M | 1 |
| Peersman, C | 1 |
| Kesteloot, H | 1 |
| Verwilghen, RL | 1 |
| González Juanatey, JR | 1 |
| Amaro Cendon, A | 1 |
| Pose Reino, A | 1 |
| Torre Carballada, A | 1 |
| Rubio Alvarez, J | 1 |
| Gil de la Peña, M | 1 |
| Khan, AH | 1 |
| Carleton, RA | 1 |
| Chown, M | 1 |
| Stoel, I | 1 |
| Hagemeijer, F | 1 |
| van Leeuwen, R | 2 |
| Meyboom, RH | 1 |
| Danilo, P | 1 |
| Baedeker, W | 1 |
| Rastetter, J | 1 |
| Bodenheimer, HC | 1 |
| Samarel, AM | 1 |
| Köhler, GD | 1 |
| Hausamen, TU | 1 |
| Weber, FW | 1 |
| Poortermans, JC | 1 |
| Majid, PA | 1 |
| Roos, JP | 1 |
| Ibáñez, L | 1 |
| Juan, J | 1 |
| Pérez, E | 1 |
| Carné, X | 1 |
| Laporte, JR | 1 |
| Munar Qués, M | 1 |
| Antich Rojas, JL | 1 |
| Vich Martorell, CL | 1 |
| Lluch Alamar, DM | 1 |
4 reviews available for aprindine and Agranulocytosis
| Article | Year |
|---|---|
Studies with aprindine.
Topics: Agranulocytosis; Animals; Aprindine; Arrhythmias, Cardiac; Cholestasis; Dogs; Electrophysiology; Hum | 1980 |
Aprindine: a review.
Topics: Administration, Oral; Agranulocytosis; Animals; Aprindine; Arrhythmias, Cardiac; Chemical and Drug I | 1980 |
Aprindine.
Topics: Administration, Oral; Agranulocytosis; Animals; Aprindine; Arrhythmias, Cardiac; Autonomic Nervous S | 1979 |
Agranulocytosis associated with aprindine and other antiarrhythmic drugs: an epidemiological approach.
Topics: Aged; Agranulocytosis; Anti-Arrhythmia Agents; Aprindine; Female; Humans; Male; Middle Aged; Retrosp | 1991 |
13 other studies available for aprindine and Agranulocytosis
| Article | Year |
|---|---|
Aprindine and agranulocytosis.
Topics: Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Bone Marrow; Humans; Indenes | 1980 |
Aprindine-induced agranulocytosis. Evidence for immunologic mechanism.
Topics: Aged; Agranulocytosis; Antibodies; Aprindine; Bone Marrow; Carbon Dioxide; Cytotoxicity, Immunologic | 1983 |
Mechanism of aprindine induced agranulocytosis: direct toxicity on CFU-C and CFU-GEMM.
Topics: Aged; Agranulocytosis; Antibody-Dependent Cell Cytotoxicity; Aprindine; Bone Marrow Cells; Granulocy | 1984 |
[Agranulocytosis caused by aprindine. Apropos of a new case].
Topics: Agranulocytosis; Aprindine; Humans; Indenes; Male; Middle Aged | 1984 |
Aprindine therapy for refractory ventricular tachycardia.
Topics: Agranulocytosis; Aprindine; Central Nervous System Diseases; Electrocardiography; Follow-Up Studies; | 1983 |
Agranulocytosis and aprindine.
Topics: Adult; Aged; Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Female; Humans; Indenes; Male; Middle | 1976 |
[Agranulocytosis after treatment with apridine].
Topics: Aged; Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Female; Humans; Indenes | 1977 |
Agranulocytosis associated with aprindine therapy.
Topics: Aged; Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Humans; Indenes; Male | 1979 |
[Drugs and acute agranulocytosis].
Topics: Agranulocytosis; Aprindine; Drug-Related Side Effects and Adverse Reactions; Humans | 1979 |
[Fatal course of agranulocytosis during antiarryhthmic aprindine therapy].
Topics: Aged; Agranulocytosis; Aprindine; Arrhythmias, Cardiac; Female; Humans; Indenes | 1977 |
[Agranulocytosis during use of aprindine].
Topics: Aged; Agranulocytosis; Aprindine; Female; Humans; Indenes; Male; Middle Aged; Netherlands | 1976 |
[Agranulocytosis after use of aprindine (Fiboran)].
Topics: Aged; Agranulocytosis; Aprindine; Humans; Indenes; Male; Middle Aged; Myocardial Infarction; Tachyca | 1976 |
[Agranulocytosis induced by aprindine. Pathogenetic considerations].
Topics: Aged; Agranulocytosis; Aprindine; Female; Humans; Indenes | 1985 |