aprepitant has been researched along with Stress-Disorders--Traumatic* in 1 studies
1 other study(ies) available for aprepitant and Stress-Disorders--Traumatic
Article | Year |
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The ups and downs of novel antiemetic drugs, part 1: substance P, 5-HT, and the neuropharmacology of vomiting.
Novel antiemetic agents such as the newly approved aprepitant (Emend) target receptors for substance P, known as neurokinin-1 (NK(1)) receptors. When NK(1) receptors are blocked in the vomiting center of the brainstem, chemotherapy-induced emesis is reduced. It is possible that blocking NK(1) receptors elsewhere in the CNS will lead to therapeutic actions in depression and other stress-related disorders. Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Area Postrema; Brain Stem; Depressive Disorder; Humans; Morpholines; Receptors, Neurokinin-1; Serotonin; Solitary Nucleus; Stress Disorders, Traumatic; Substance P; Vomiting | 2003 |