apraclonidine has been researched along with Complication, Postoperative in 34 studies
apraclonidine: relieves postoperative intraocular pressure following trabeculoplasty; RN given refers to parent cpd
apraclonidine : An imidazoline that is 2-amino 4,5-dihydro-1H-imidazoline in which one of the exocyclic amino hydrogens has been replaced by a 4-amino-2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness of prophylactic topical apraclonidine 1% in preventing an intraocular pressure (IOP) rise in the early period after uneventful phacoemulsification with intraocular lens (IOL) implantation." | 9.10 | Preventing intraocular pressure increase after phacoemulsification and the role of perioperative apraclonidine. ( Desai, SP; Kasetti, SR; Sivakumar, S; Sunderraj, P, 2002) |
| "Topical apraclonidine hydrochloride 1% is effective for controlling the intraocular pressure (IOP) rise following argon laser trabeculoplasty (ALT)." | 9.08 | Apraclonidine 0.5% versus 1% for controlling intraocular pressure elevation after argon laser trabeculoplasty. ( Allingham, RR; Assalian, AA; Shields, MB; Threlkeld, AB, 1996) |
| "0% apraclonidine in preventing laser-induced intraocular pressure (IOP) elevation after trabeculoplasty, neodymium: YAG (Nd: YAG) iridotomy, and capsulotomy." | 9.08 | Apraclonidine and anterior segment laser surgery. Comparison of 0.5% versus 1.0% apraclonidine for prevention of postoperative intraocular pressure rise. ( Gieser, DK; Grewal, RK; Karalekas, DP; Krupin, T; McDaniel, DL; Rosenberg, LF; Ruderman, J; Siegfried, C; Williams, R, 1995) |
| "Apraclonidine effectively decreased large IOP elevations in glaucomatous eyes undergoing trabeculectomy combined with extracapsular cataract surgery." | 9.07 | Effect of topical apraclonidine on the frequency of intraocular pressure elevations after combined extracapsular cataract extraction and trabeculectomy. ( Robin, AL, 1993) |
| "We evaluated the prophylactic effect of 1% apraclonidine HCl in controlling the increase in intraocular pressure after Nd:YAG posterior capsulotomy in a large, multicenter double-masked clinical trial." | 9.07 | Prophylactic use of apraclonidine for intraocular pressure increase after Nd:YAG capsulotomies. ( Brint, SF; Burk, LL; deFaller, JM; McCarty, GR; Olander, KW; Silverstone, DE; Taylor, RB, 1992) |
| "We studied apraclonidine hydrochloride (aplonidine hydrochloride or ALO 2145), an alpha-agonist, for its effect on the intraocular pressure (IOP) rise following neodymium-YAG posterior capsulotomy (YPC)." | 9.06 | Prevention of the rise in intraocular pressure following neodymium-YAG posterior capsulotomy using topical 1% apraclonidine. ( Brown, RH; Crandall, AS; Pollack, IP; Robin, AL; Stewart, RH; White, GL, 1988) |
| "0% apraclonidine in preventing intraocular pressure (IOP) spike after argon laser trabeculoplasty (ALT) in patients on chronic apraclonidine therapy compared with patients not on chronic apraclonidine use." | 7.69 | Chronic use of apraclonidine decreases its moderation of post-laser intraocular pressure spikes. ( Birt, CM; Chung, HS; Hakimzadeh, R; Juzych, MS; Kim, C; Lee, D; Levin, DS; Shin, DH, 1997) |
| "We evaluated the effectiveness of topical apraclonidine (ALO 2145, p-amino clonidine hydrochloride) in suppressing an acute postoperative intraocular pressure (IOP) rise following Nd:YAG laser iridotomy." | 7.67 | Use of apraclonidine to reduce acute intraocular pressure rise following Q-switched Nd:YAG laser iridotomy. ( Kitazawa, Y; Sugiyama, K; Taniguchi, T, 1989) |
| "To determine the 1- and 3-hour changes in intraocular pressure after neodymium:yttrium-aluminum-garnet (Nd:YAG) capsulotomy in pseudophakic patients with glaucoma and to determine the effect of acetazolamide and apraclonidine on these changes." | 5.11 | Neodymium:yttrium-aluminum-garnet capsulotomy and intraocular pressure in pseudophakic patients with glaucoma. ( Barnes, EA; Behrend, M; Cahill, A; Kehoe, B; Murdoch, IE; Subramaniam, S, 2004) |
| "To evaluate the effectiveness of prophylactic topical apraclonidine 1% in preventing an intraocular pressure (IOP) rise in the early period after uneventful phacoemulsification with intraocular lens (IOL) implantation." | 5.10 | Preventing intraocular pressure increase after phacoemulsification and the role of perioperative apraclonidine. ( Desai, SP; Kasetti, SR; Sivakumar, S; Sunderraj, P, 2002) |
| "Topical apraclonidine hydrochloride 1% is effective for controlling the intraocular pressure (IOP) rise following argon laser trabeculoplasty (ALT)." | 5.08 | Apraclonidine 0.5% versus 1% for controlling intraocular pressure elevation after argon laser trabeculoplasty. ( Allingham, RR; Assalian, AA; Shields, MB; Threlkeld, AB, 1996) |
| "0% apraclonidine in preventing laser-induced intraocular pressure (IOP) elevation after trabeculoplasty, neodymium: YAG (Nd: YAG) iridotomy, and capsulotomy." | 5.08 | Apraclonidine and anterior segment laser surgery. Comparison of 0.5% versus 1.0% apraclonidine for prevention of postoperative intraocular pressure rise. ( Gieser, DK; Grewal, RK; Karalekas, DP; Krupin, T; McDaniel, DL; Rosenberg, LF; Ruderman, J; Siegfried, C; Williams, R, 1995) |
| "Apraclonidine effectively decreased large IOP elevations in glaucomatous eyes undergoing trabeculectomy combined with extracapsular cataract surgery." | 5.07 | Effect of topical apraclonidine on the frequency of intraocular pressure elevations after combined extracapsular cataract extraction and trabeculectomy. ( Robin, AL, 1993) |
| "We evaluated the prophylactic effect of 1% apraclonidine HCl in controlling the increase in intraocular pressure after Nd:YAG posterior capsulotomy in a large, multicenter double-masked clinical trial." | 5.07 | Prophylactic use of apraclonidine for intraocular pressure increase after Nd:YAG capsulotomies. ( Brint, SF; Burk, LL; deFaller, JM; McCarty, GR; Olander, KW; Silverstone, DE; Taylor, RB, 1992) |
| "To determine the effect of apraclonidine hydrochloride on the acute intraocular pressure (IOP) rise after argon laser iridotomy (ALI), a double-masked comparative study was carried out." | 5.07 | Effect of apraclonidine hydrochloride on acute introacular pressure rise after argon laser iridotomy. ( Hong, C; Park, WH; Sohn, YH; Song, KY, 1991) |
| "The effect of an alpha adrenergic agonist, ALO 2145 (para-amino-clonidine [PAC]), was examined in a double-masked, multicenter study on the postoperative intraocular pressure (IOP) elevation after laser surgery in 165 patients (83 trabeculoplasty, 36 iridotomy, and 46 capsulotomy)." | 5.06 | ALO 2145 reduces the intraocular pressure elevation after anterior segment laser surgery. ( Brown, RH; Crandall, AS; DeFaller, JM; Gaasterland, DE; Higginbotham, EJ; Lynch, MG; Mandell, AI; Schwartz, AL; Stewart, RH; Wilensky, JT, 1988) |
| "We studied apraclonidine hydrochloride (aplonidine hydrochloride or ALO 2145), an alpha-agonist, for its effect on the intraocular pressure (IOP) rise following neodymium-YAG posterior capsulotomy (YPC)." | 5.06 | Prevention of the rise in intraocular pressure following neodymium-YAG posterior capsulotomy using topical 1% apraclonidine. ( Brown, RH; Crandall, AS; Pollack, IP; Robin, AL; Stewart, RH; White, GL, 1988) |
| " Two children with anisocoria, one of whom had Horner Syndrome confirmed with apraclonidine 1% and the other, in whom an apraclonidine test ruled out this syndrome but in whom pilocarpine 0." | 3.75 | [Usefulness of apraclonidine in the diagnosis of Horner syndrome]. ( Alias, E; Díaz, S; Fernández, FJ; Ferrer, C; González, I; Honrubia, FM; Pérez-Iñigo, MA, 2009) |
| "0% apraclonidine in preventing intraocular pressure (IOP) spike after argon laser trabeculoplasty (ALT) in patients on chronic apraclonidine therapy compared with patients not on chronic apraclonidine use." | 3.69 | Chronic use of apraclonidine decreases its moderation of post-laser intraocular pressure spikes. ( Birt, CM; Chung, HS; Hakimzadeh, R; Juzych, MS; Kim, C; Lee, D; Levin, DS; Shin, DH, 1997) |
| "We evaluated the effectiveness of topical apraclonidine (ALO 2145, p-amino clonidine hydrochloride) in suppressing an acute postoperative intraocular pressure (IOP) rise following Nd:YAG laser iridotomy." | 3.67 | Use of apraclonidine to reduce acute intraocular pressure rise following Q-switched Nd:YAG laser iridotomy. ( Kitazawa, Y; Sugiyama, K; Taniguchi, T, 1989) |
| "The intraocular pressures were measured at regular intervals during the 6-months follow-up period." | 2.80 | Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty. ( Anctil, JL; Champagne, S; Des Marchais, B; Goyette, A; Lajoie, C, 2015) |
| "Apraclonidine is a alpha 2 adrenergic agonic which is a para-amino derivative of clonidine." | 2.39 | [Effect and side effects of apraclonidine]. ( Stewart, WC, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.71) | 18.7374 |
| 1990's | 14 (41.18) | 18.2507 |
| 2000's | 10 (29.41) | 29.6817 |
| 2010's | 5 (14.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Champagne, S | 1 |
| Anctil, JL | 1 |
| Goyette, A | 1 |
| Lajoie, C | 1 |
| Des Marchais, B | 1 |
| Brown, M | 1 |
| Zhang, L | 1 |
| Weizer, JS | 1 |
| Musch, DC | 1 |
| Pérez-Iñigo, MA | 1 |
| González, I | 1 |
| Fernández, FJ | 1 |
| Díaz, S | 1 |
| Ferrer, C | 1 |
| Alias, E | 1 |
| Honrubia, FM | 1 |
| Shin, RK | 1 |
| Cheek, AG | 1 |
| Ramos, R | 1 |
| Ureña, A | 1 |
| Rivas, F | 1 |
| Macia, I | 1 |
| Rosado, G | 1 |
| Pequeño, S | 1 |
| Masuet, C | 1 |
| Badia, M | 1 |
| Miguel, M | 1 |
| Delgado, MA | 1 |
| Escobar, I | 1 |
| Moya, J | 1 |
| Kasetti, SR | 1 |
| Desai, SP | 1 |
| Sivakumar, S | 1 |
| Sunderraj, P | 1 |
| Barnes, EA | 1 |
| Murdoch, IE | 1 |
| Subramaniam, S | 1 |
| Cahill, A | 1 |
| Kehoe, B | 1 |
| Behrend, M | 1 |
| Chen, TC | 2 |
| Aslanides, IM | 1 |
| Tsiklis, NS | 1 |
| Pallikaris, IG | 1 |
| Jankov, MR | 1 |
| Coskunseven, E | 1 |
| Ozkilic, E | 1 |
| Unal, M | 1 |
| Yücel, I | 1 |
| Akar, Y | 1 |
| Scuderi, G | 1 |
| Regine, F | 1 |
| Perdicchi, A | 1 |
| Mannino, G | 1 |
| Recupero, SM | 1 |
| Bömer, TG | 2 |
| Lagrèze, WD | 2 |
| Funk, J | 2 |
| Robin, AL | 4 |
| Azuara-Blanco, A | 1 |
| Araujo, SV | 1 |
| Lu, DW | 1 |
| Lesk, MR | 1 |
| Katz, LJ | 1 |
| Spaeth, GL | 1 |
| Threlkeld, AB | 1 |
| Assalian, AA | 1 |
| Allingham, RR | 1 |
| Shields, MB | 2 |
| Stewart, WC | 1 |
| Rosenberg, LF | 1 |
| Krupin, T | 1 |
| Ruderman, J | 1 |
| McDaniel, DL | 1 |
| Siegfried, C | 1 |
| Karalekas, DP | 1 |
| Grewal, RK | 1 |
| Gieser, DK | 1 |
| Williams, R | 1 |
| Chung, HS | 1 |
| Shin, DH | 1 |
| Birt, CM | 1 |
| Kim, C | 1 |
| Lee, D | 1 |
| Levin, DS | 1 |
| Hakimzadeh, R | 1 |
| Juzych, MS | 1 |
| Sciscio, A | 1 |
| Casswell, AG | 1 |
| Ang, RT | 1 |
| Grosskreutz, CL | 1 |
| Pasquale, LR | 1 |
| Fan, JT | 1 |
| Stîngu, C | 1 |
| Cristescu, A | 1 |
| Dărăban, C | 1 |
| Ioniţă, M | 1 |
| Serghiescu, S | 1 |
| Silverstone, DE | 1 |
| Brint, SF | 1 |
| Olander, KW | 1 |
| Taylor, RB | 1 |
| McCarty, GR | 1 |
| deFaller, JM | 2 |
| Burk, LL | 1 |
| Ofner, S | 1 |
| Samples, JR | 1 |
| van Buskirk, EM | 1 |
| Hong, C | 1 |
| Song, KY | 1 |
| Park, WH | 1 |
| Sohn, YH | 1 |
| Allf, BE | 1 |
| Fernandez-Bahamonde, JL | 1 |
| Alcaraz-Michelli, V | 1 |
| King, MH | 1 |
| Richards, DW | 1 |
| Kitazawa, Y | 1 |
| Taniguchi, T | 1 |
| Sugiyama, K | 1 |
| Pollack, IP | 2 |
| House, B | 1 |
| Enger, C | 1 |
| Brown, RH | 2 |
| Stewart, RH | 2 |
| Lynch, MG | 1 |
| Crandall, AS | 2 |
| Mandell, AI | 1 |
| Wilensky, JT | 1 |
| Schwartz, AL | 1 |
| Gaasterland, DE | 1 |
| Higginbotham, EJ | 1 |
| White, GL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Short-term Intraocular Pressure Control After YAG Iridotomy - Comparison Between Brimonidine 0.1% vs. 0.2%[NCT01417858] | 50 participants (Anticipated) | Interventional | 2010-11-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for apraclonidine and Complication, Postoperative
| Article | Year |
|---|---|
Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty.
Topics: Adrenergic alpha-2 Receptor Agonists; Antihypertensive Agents; Brimonidine Tartrate; Clonidine; Conj | 2017 |
[Effect and side effects of apraclonidine].
Topics: Adrenergic alpha-Agonists; Clonidine; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Press | 1996 |
20 trials available for apraclonidine and Complication, Postoperative
| Article | Year |
|---|---|
Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modalit | 2015 |
Preventing intraocular pressure increase after phacoemulsification and the role of perioperative apraclonidine.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Clonidine; Double-Blind | 2002 |
Neodymium:yttrium-aluminum-garnet capsulotomy and intraocular pressure in pseudophakic patients with glaucoma.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Antihyperte | 2004 |
Brimonidine 0.15% versus apraclonidine 0.5% for prevention of intraocular pressure elevation after anterior segment laser surgery.
Topics: Adrenergic alpha-Agonists; Aged; Anterior Eye Segment; Antihypertensive Agents; Blood Pressure; Brim | 2005 |
Apraclonidine and LASIK.
Topics: Administration, Topical; Adolescent; Adrenergic alpha-Agonists; Adult; Clonidine; Conjunctival Disea | 2005 |
Brinzolamide 1% versus apraclonidine 0.5% to prevent intraocular pressure elevation after neodymium:YAG laser posterior capsulotomy.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Clonidine; | 2006 |
Comparative efficacy of acetazolamide and apraclonidine in the control of intraocular pressure following phacoemulsification.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Aged; Aged, | 2006 |
Intraocular pressure rise after phacoemulsification with posterior chamber lens implantation: effect of prophylactic medication, wound closure, and surgeon's experience.
Topics: Acetazolamide; Adrenergic alpha-Antagonists; Aged; Clonidine; Female; Humans; Intraocular Pressure; | 1995 |
[Increased intraocular pressure after cataract extraction--effect of surgical technique, surgical procedure and preventive drug administration. A prospective, randomized double-blind study].
Topics: Acetazolamide; Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Cataract Extraction; Clinical Com | 1995 |
Effect of topical apraclonidine on the frequency of intraocular pressure elevations after combined extracapsular cataract extraction and trabeculectomy.
Topics: Adrenergic alpha-Agonists; Aged; Cataract Extraction; Clonidine; Double-Blind Method; Female; Glauco | 1993 |
Apraclonidine 0.5% versus 1% for controlling intraocular pressure elevation after argon laser trabeculoplasty.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Clonidine; Follow-Up Studies; Glaucoma; Humans; | 1996 |
Apraclonidine and anterior segment laser surgery. Comparison of 0.5% versus 1.0% apraclonidine for prevention of postoperative intraocular pressure rise.
Topics: Adrenergic alpha-Agonists; Aged; Anterior Eye Segment; Clonidine; Double-Blind Method; Glaucoma; Hum | 1995 |
Effectiveness of apraclonidine 1% in preventing intraocular pressure rise following macular hole surgery.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Blood Pressure; Clonidine; Double-Blind Method; | 2001 |
Brimonidine 0.2% versus apraclonidine 0.5% for prevention of intraocular pressure elevations after anterior segment laser surgery.
Topics: Adrenergic alpha-Agonists; Aged; Anterior Eye Segment; Blood Pressure; Brimonidine Tartrate; Clonidi | 2001 |
Prophylactic use of apraclonidine for intraocular pressure increase after Nd:YAG capsulotomies.
Topics: Adrenergic alpha-Agonists; Aged; Cataract Extraction; Clonidine; Double-Blind Method; Female; Humans | 1992 |
Effect of apraclonidine hydrochloride on acute introacular pressure rise after argon laser iridotomy.
Topics: Acute Disease; Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Double-Blind Method; Female; Glauc | 1991 |
The combined use of apraclonidine and pilocarpine during laser iridotomy in a Hispanic population.
Topics: Aged; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Gl | 1990 |
Effects of ALO 2145 on intraocular pressure following argon laser trabeculoplasty.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Clinical Trials as Topic; Clonidine; Double-Blind Method; Fe | 1987 |
ALO 2145 reduces the intraocular pressure elevation after anterior segment laser surgery.
Topics: Aged; Anterior Eye Segment; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans | 1988 |
Prevention of the rise in intraocular pressure following neodymium-YAG posterior capsulotomy using topical 1% apraclonidine.
Topics: Administration, Topical; Aged; Cataract Extraction; Clonidine; Double-Blind Method; Female; Humans; | 1988 |
12 other studies available for apraclonidine and Complication, Postoperative
| Article | Year |
|---|---|
Preventing, identifying, and managing cosmetic procedure complications, part 1: soft-tissue augmentation and botulinum toxin injections.
Topics: Adrenergic alpha-2 Receptor Agonists; Blepharoptosis; Botulinum Toxins; Clonidine; Cosmetic Techniqu | 2016 |
[Usefulness of apraclonidine in the diagnosis of Horner syndrome].
Topics: Adrenergic alpha-Agonists; Adult; Anisocoria; Birth Injuries; Brachial Plexus; Clonidine; Cocaine; D | 2009 |
Teaching NeuroImages: Positive apraclonidine test in Horner syndrome.
Topics: Adrenergic alpha-Agonists; Adult; Blepharoptosis; Clonidine; Diskectomy; Female; Horner Syndrome; Hu | 2011 |
Impact of T3 thoracoscopic sympathectomy on pupillary function: a cause of partial Horner's syndrome?
Topics: Adolescent; Adult; Clonidine; Equipment Design; Horner Syndrome; Humans; Hyperhidrosis; Intraoperati | 2012 |
Effects of apraclonidine on short-term outcome of glaucoma surgery.
Topics: Adrenergic alpha-Agonists; Aged; Clonidine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Mi | 1996 |
Chronic use of apraclonidine decreases its moderation of post-laser intraocular pressure spikes.
Topics: Adrenergic alpha-Agonists; Aged; Clonidine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressu | 1997 |
[Iopidine in the control of intraocular pressure after glaucoma laser treatment].
Topics: Adrenergic alpha-Agonists; Clonidine; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Postope | 2001 |
Apraclonidine and argon laser trabeculoplasty.
Topics: Adrenergic alpha-Agonists; Clonidine; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Pilocar | 1992 |
Early intraocular pressure response to laser trabeculoplasty 180 degrees without apraclonidine versus 360 degrees with apraclonidine.
Topics: Adrenergic alpha-Agonists; Aged; Clonidine; Female; Glaucoma; Humans; Intraocular Pressure; Laser Th | 1991 |
Near syncope and chest tightness after administration of apraclonidine before argon laser iridotomy.
Topics: Aged; Argon; Chest Pain; Clonidine; Female; Humans; Intraocular Pressure; Iris; Laser Therapy; Posto | 1990 |
The role of apraclonidine hydrochloride in laser therapy for glaucoma.
Topics: Acetazolamide; Adult; Aged; Animals; Clonidine; Epinephrine; Female; Glaucoma, Open-Angle; Humans; I | 1989 |
Use of apraclonidine to reduce acute intraocular pressure rise following Q-switched Nd:YAG laser iridotomy.
Topics: Aged; Clonidine; Female; Glaucoma; Gonioscopy; Humans; Intraocular Pressure; Iris; Laser Therapy; Ma | 1989 |