apoptolidin has been researched along with Leukemia* in 2 studies
2 other study(ies) available for apoptolidin and Leukemia
| Article | Year |
|---|---|
A wrench in the motor.
Topics: Adenosine Triphosphate; Humans; Leukemia; Macrolides | 2022 |
Apoptolidin family glycomacrolides target leukemia through inhibition of ATP synthase.
Cancer cells have long been recognized to exhibit unique bioenergetic requirements. The apoptolidin family of glycomacrolides are distinguished by their selective cytotoxicity towards oncogene-transformed cells, yet their molecular mechanism remains uncertain. We used photoaffinity analogs of the apoptolidins to identify the F Topics: Adenosine Triphosphate; Humans; Leukemia; Macrolides; Mitochondrial Proton-Translocating ATPases; Neoplasms | 2022 |