Page last updated: 2024-08-17

apomorphine and Impotence

apomorphine has been researched along with Impotence in 142 studies

Research

Studies (142)

TimeframeStudies, this research(%)All Research%
pre-19904 (2.82)18.7374
1990's8 (5.63)18.2507
2000's110 (77.46)29.6817
2010's18 (12.68)24.3611
2020's2 (1.41)2.80

Authors

AuthorsStudies
Bhatia, P; Brioni, JD; Chang, R; Cowart, M; Daanen, JF; Donnelly-Roberts, DL; Hollingsworth, PR; Hsieh, GC; Kolasa, T; Latshaw, SP; Lynch, JJ; Martino, BR; Miller, LN; Moreland, RB; Nakane, M; Namovic, MT; Nelson, SL; Patel, M; Rohde, J; Stewart, AO; Sullivan, JP; Terranova, MA; Uchic, ME1
Bhatia, P; Brioni, JD; Chang, R; Donnelly-Roberts, DL; El Kouhen, O; Hakeem, AA; Henry, R; Hollingsworth, PR; Hsieh, GC; Kolasa, T; Marsh, KC; Martino, B; Matulenko, MA; Miller, LN; Moreland, RB; Mortell, K; Nakane, M; Namovic, MT; Patel, MV; Stewart, AO; Terranova, MA; Uchic, ME; Wetter, JM1
Brioni, JD; Chang, R; Cowart, MD; Darbyshire, JF; Donnelly-Roberts, DL; El-Kouhen, OF; Gintant, G; Hakeem, AA; Hollingsworth, PR; Hsieh, GC; Kolasa, T; Marsh, KC; Martin, R; Martino, BR; Matulenko, MA; Miller, LN; Moreland, RB; Mortell, K; Nakane, M; Namovic, MT; Nelson, SL; Patel, MV; Rohde, JJ; Stewart, AO; Sullivan, JP; Terranova, MA; Uchic, ME; Wetter, JM1
Chen, G; Dong, J; Feng, N; Hu, L; Wu, Y; Yu, D1
Crestani, S; da Silva-Santos, JE; Leitolis, A; Linder, ÁE1
Ballesteros, J; Guillén, V; Lopez-Argumedo, M; Rueda, JR; Solà, I1
Chen, G; Chen, J; Chen, Y; Dai, Y; Jiang, H; Yang, B; Yu, W; Zang, F; Zhu, L1
Chen, G; Chen, J; Chen, Y; Dai, Y; Yang, B; Yu, W1
Albersen, M; Campbell, J; Milenkovic, U; Roussel, E1
Wang, BQ1
Elhenawee, M; Hashem, H; Ibrahim, AE1
Fan, Q; Jin, BF; Li, TF; Liu, T; Sun, ZX; Zhou, YC1
Chen, M; Liu, L; Qin, WB; Qiu, HB; Wang, BX; Wang, JT; Xu, H1
Hou, SC; Liu, W; Luan, X; Qi, HY; Sun, LJ; Wang, WM; Weng, BW; Xu, L; Zhu, H1
Alkan, E; Balbay, MD; Basar, MM; Halici, Z; Karakus, E; Ugan, RA; Un, H1
Afif-Abdo, J; Cortado, P; Damião, R; Faria, G; Glina, S; Koff, W; Pompeo, AC; Sabaneeff, J; Teloken, C; Torres, LO; Wroclawski, E; Yamasaki, R1
Colpi, GM; Cormio, L; Giammusso, B; Guastella, B; Ludovico, G; Montorsi, F; Panzironi, C; Ponchietti, R; Soli, M1
Nyírády, P; Riesz, P; Rusz, A1
Mulhall, JP4
Main, M; Morgan, F; Riley, A1
Cheng, B; Hu, W; Li, S; Liu, T; Tian, Y1
Adams, MA; Adams, SM; Blaser, MC; Hannan, JL; Oldfield, L; Pang, JJ; Pang, SC1
Albersen, M; Lue, TF; Mwamukonda, KB; Shindel, AW1
Kumar, R; Nehra, A1
Albersen, M; Lue, TF; Orabi, H1
Ribarič, S1
Bretsztajn, L; Eardley, I; Mohee, A1
Thomas, JA1
Ichise, J; Yokokawa, K1
Kumon, H; Nagai, A1
Lyngdorf, P1
Anastasiadis, AG; Shabsigh, R1
Cestari, A; Deho', F; Guazzoni, G; Montorsi, F; Rigatti, P; Salonia, A; Stief, C1
Hauri, D; Müntener, M; Praz, V; Suter, S1
Anchisi, D; De Vito, ML; Deho, F; Fazio, F; Heaton, J; Montorsi, F; Perani, D; Rigatti, P; Rigiroli, P; Salonia, A; Scifo, P1
Berding, G; Bergh, S; Hagemann, JH; Jonas, U; Knapp, WH; Sleep, DJ; Stief, CG1
Gallé, G; Trummer, H1
Tan, RS1
Buller, KM; Crane, JW; Day, TA; Spencer, SJ1
Montorsi, F1
Amornvejsukit, T; Choeypunt, N; Kongkanand, A; Opanuraks, J; Tantiwong, A; Tantiwongse, K1
Costa, P1
Hedon, F1
Erdei, E; Papp, G1
Steers, WD1
Anchisi, D; Fazio, F; Heaton, JP; Montorsi, F; Perani, D; Rigatti, P; Rigiroli, P; Salonia, A; Scifo, P; Zanoni, M1
Gaines, KK1
Schultheiss, D; Stief, CG1
Agnello, C; Caruso, S; DiMari, L; Farina, M; Giammusso, B; Intelisano, G1
Martínez, R; Pomerol, JM; Puigvert, A; Rodríguez-Villalba, R1
Curt, A; Hauri, D; Reitz, A; Schurch, B; Strebel, RT; Tenti, G1
Bertol, E; Fineschi, V; Karch, SB; Mari, F; Riezzo, I1
Athanasopoulos, A; Barbalias, G; Chrysanthopoulou, A; Giannitsas, K; Gyftopoulos, K; Markou, SA; Perimenis, P; Tsota, I1
Hellstrom, WJ; Kendirci, M1
Briganti, A; Gallina, A; Montorsi, F; Rigatti, P; Salonia, A; Suardi, N1
Jackson, G1
Eardley, I; Edwards, A; Hole, J; MacDonagh, R; Wright, P1
Athanasopoulos, A; Barbalias, G; Giannitsas, K; Gyftopoulos, K; Liatsikos, E; Markou, S; Perimenis, P1
Engelmann, U; Sommer, F1
Basu, A; Ryder, RE1
Almasio, PL; Anello, G; Curto, F; Pavone, C; Pavone-Macaluso, M; Serretta, V1
Fontana, F; Frea, B; Gontero, P; Montorsi, F; Zitella, A1
Kloner, RA; Reffelmann, T1
Hatzichristou, DG; Hatzimouratidis, K1
Hu, LQ; Hu, WL1
Dinsmore, WW1
Hellstrom, WJ; Kendirci, M; Walls, MM1
Adaikan, G; Becher, E; Brock, G; Carrier, S; Carson, C; Christ, G; Corbin, J; DeBusk, R; Eardley, I; Francis, S; Hedlund, H; Hutter, A; Jackson, G; Kloner, R; Lin, CS; Lin, S; McCullough, A; McVary, K; Nehra, A; Padma-Nathan, H; Porst, H; Schulman, C; Seftel, A; Sharlip, I; Stief, C; Teloken, C1
Xu, G; Xu, Y1
Barbieri, L; Briganti, A; Chun, FK; Dehò, F; Karakiewicz, PI; Montorsi, F; Rigatti, P; Salonia, A; Zanni, G1
Dachille, G; Ludovico, GM; Pagliarulo, A; Pagliarulo, V; Ralph, D1
Landtblom, AM1
Boshier, A; Maclennan, KM; Shakir, SA; Wilton, LV1
Gopalakrishanan, G; Tharyan, P1
Behre, HM; Burkart, M; Jungwirth, A; Porst, H1
Görlich, HD; Potempa, DM; Potempal, AJ; Stolpmann, RM1
Tan, DQ; Yao, Y; Zhang, J1
Miner, MM; Seftel, AD1
Fu, Q; Lv, JJ; Zhang, H1
Carson, CC1
Cheng, Y; Li, YG; Wei, AY1
Kiely, ME; Lal, S; Thavundayil, JX1
Adams, MA; el-Rashidy, R; Heaton, JP; Johnston, B; Morales, A1
Giuliano, F1
Hughes, AJ; O'Sullivan, JD1
Moncada Iribarren, I; Sáenz de Tejada, I1
Trummer, H1
Gottlieb, S1
Baba, K; Carrier, S; Iwamoto, T; Lue, TF; Morgan, DM; Nunes, L; Yajima, M1
Cowley, G1
Buttler, S; Dula, E; Edmonds, A; Keating, W; O'neil, J; Siami, PF1
Heaton, JP3
Roumeguère, T1
Segraves, RT1
Cohan, P; Korenman, SG1
Andersson, KE1
Giuliano, F; Padma-Nathan, H1
Bukofzer, S; Dula, E; George, M; Perdok, R1
Porst, H1
Wagner, G1
Morales, A1
Bukofzer, S; Livesey, N1
Cutler, D1
Bukofzer, S; Edmonds, AL; George, M; Mulhall, JP1
Aversa, A; Fabbri, A1
Hatzichristou, DG; Pescatori, ES1
Argiolas, A; Hedlund, H1
Mirone, VG; Stief, CG1
Rampin, O1
Buvat, J; Montorsi, F1
Altwein, JE; Heaton, JP1
Buttler, S; Edmonds, A; Fagan, TC; Marbury, T; Taylor, A1
Altwein, JE; Keuler, FU1
Allard, J; Giuliano, F2
Anastasiadis, AG; Burchardt, M; Ghafar, MA; Shabsigh, R1
Bukofzer, S; Hibberd, M; Mallard, N; Ströberg, P; Von Keitz, AT1
Carrier, S; Simmerman, N; Vachon, P; Zahran, AR1
Castaneda, J; Castell, R; Hurley, D; Lammers, PI; Lipezker, M; Loehr, LA; Lowrey, F; Ponce de Leon, R; Rubio-Aurioles, E1
Dean, J; Heaton, JP; Sleep, DJ1
Köhn, FM1
O'Sullivan, JD1
Adams, MA; Brien, SE; Gofton, WT; Heaton, JP; Smallegange, C1
Lenk, S1
Benassi-Benelli, A; Ferrari, F1
Ackman, CF; Assalian, P; Kiely, ME; Lal, S; Stewart, JD; Thavundayil, JX1
Bari, M; Segraves, K; Segraves, RT; Spirnak, P1
Dubrovsky, B; Grassino, A; Kiely, ME; Lal, S; Nair, NP; Tesfaye, Y; Thavundayil, JX; Thompson, TR1
Alexandre, L; Benoit, G; Bensadoun, H; Jardin, A; Puech, A1
Ackman, D; Blundell, P; Gardiner, RJ; Lal, S; Laryea, E; Nair, NP; Negrete, J; Thavundayil, JX1

Reviews

60 review(s) available for apomorphine and Impotence

ArticleYear
Apomorphine for the Treatment of Erectile Dysfunction: Systematic Review and Meta-Analysis.
    Archives of sexual behavior, 2020, Volume: 49, Issue:8

    Topics: Administration, Sublingual; Adult; Aged; Apomorphine; Erectile Dysfunction; Humans; Male; Middle Aged; Treatment Outcome; Young Adult

2020
An update on emerging drugs for the treatment of erectile dysfunction.
    Expert opinion on emerging drugs, 2018, Volume: 23, Issue:4

    Topics: Animals; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Phosphodiesterase 5 Inhibitors; Vasodilator Agents

2018
Future directions in erectile dysfunction therapy.
    Postgraduate medicine, 2000, Volume: 107, Issue:6 Suppl Ed

    Topics: Adrenergic alpha-Antagonists; Apomorphine; Clinical Trials as Topic; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Phentolamine; Phosphodiesterase Inhibitors

2000
Evaluation and treatment of erectile dysfunction.
    The Medical clinics of North America, 2011, Volume: 95, Issue:1

    Topics: Apomorphine; Equipment and Supplies; Erectile Dysfunction; Humans; Male; Phosphodiesterase 5 Inhibitors; Primary Health Care; Referral and Consultation; Urogenital Surgical Procedures

2011
Central nervous system agents and erectile dysfunction.
    The Urologic clinics of North America, 2011, Volume: 38, Issue:2

    Topics: alpha-MSH; Amino Acids; Apomorphine; Central Nervous System Agents; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Melanocortins; Nitric Oxide; Penile Erection; Peptides, Cyclic; Phosphodiesterase 5 Inhibitors; Selective Serotonin Reuptake Inhibitors

2011
The pharmacological properties and therapeutic use of apomorphine.
    Molecules (Basel, Switzerland), 2012, May-07, Volume: 17, Issue:5

    Topics: Alzheimer Disease; Animals; Apomorphine; Dogs; Dopamine Agonists; Erectile Dysfunction; Female; Humans; Male; Parkinson Disease; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Substance-Related Disorders

2012
The evaluation of apomorphine for the treatment of erectile dysfunction.
    Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:11

    Topics: Administration, Sublingual; Animals; Apomorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Erectile Dysfunction; Humans; Male; Randomized Controlled Trials as Topic; Treatment Failure; United States

2012
Pharmacological aspects of erectile dysfunction.
    Japanese journal of pharmacology, 2002, Volume: 89, Issue:2

    Topics: Adult; Aged; Alprostadil; Apomorphine; Drug Interactions; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Erection; Phentolamine; Piperazines; Purines; Sildenafil Citrate; Sulfones; Testosterone; Trazodone

2002
[Preclinical studies of apomorphine hydrochloride].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 6

    Topics: Animals; Apomorphine; Biogenic Monoamines; Brain; Dopamine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Oxytocin; Penile Erection; Penis; Rats

2002
[Clinical evaluation of apomorphine HCl].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 6

    Topics: Apomorphine; Clinical Trials as Topic; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Randomized Controlled Trials as Topic

2002
Erectile dysfunction.
    Annual review of medicine, 2003, Volume: 54

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Alprostadil; Apomorphine; Brain; Cyclic Nucleotide Phosphodiesterases, Type 5; Erectile Dysfunction; Humans; Male; Penile Prosthesis; Penis; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Sildenafil Citrate; Sulfones

2003
Pharmacological management of erectile dysfunction.
    BJU international, 2003, Volume: 91, Issue:5

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Carbolines; Drug Combinations; Erectile Dysfunction; Humans; Imidazoles; Injections; Male; Papaverine; Phentolamine; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents

2003
[Erectile dysfunction: reasonable diagnostics and treatment in general practice].
    Praxis, 2003, Jan-29, Volume: 92, Issue:5

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Age Factors; Aged; Algorithms; Alprostadil; Apomorphine; Cohort Studies; Contraindications; Dopamine Agonists; Erectile Dysfunction; Family Practice; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; Piperazines; Purines; Risk Factors; Sexual Partners; Sildenafil Citrate; Sulfones; Vasodilator Agents; Yohimbine

2003
The etiology of erectile dysfunction and mechanisms by which drugs improve erection.
    Drugs of today (Barcelona, Spain : 1998), 2003, Volume: 39, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Apomorphine; Erectile Dysfunction; Humans; Male; Penile Erection; Phentolamine; Smoking

2003
Novel treatment options for overlapping yet distinct erectile dysfunction and andropause syndromes.
    Current opinion in investigational drugs (London, England : 2000), 2003, Volume: 4, Issue:4

    Topics: Androgens; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Testosterone

2003
Tolerability and safety of apomorphine SL (Ixense (TM) ).
    International journal of impotence research, 2003, Volume: 15 Suppl 2

    Topics: Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male

2003
Multidimensional nature of apomorphine SL (Ixense) therapy.
    International journal of impotence research, 2003, Volume: 15 Suppl 2

    Topics: Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Penis

2003
Anxiety and erectile dysfunction: a global approach to ED enhances results and quality of life.
    International journal of impotence research, 2003, Volume: 15 Suppl 2

    Topics: Anxiety; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Psychotherapy; Quality of Life

2003
[Conservative treatment of erectile dysfunction].
    Orvosi hetilap, 2003, Jun-01, Volume: 144, Issue:22

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Imidazoles; Impotence, Vasculogenic; Injections; Male; Nitric Oxide; Papaverine; Phosphodiesterase Inhibitors; Piperazines; Psychotherapy; Purines; Sildenafil Citrate; Sulfones; Triazines; Vacuum; Vardenafil Dihydrochloride; Vasodilator Agents

2003
Viability and safety of combination drug therapies for erectile dysfunction.
    The Journal of urology, 2003, Volume: 170, Issue:2 Pt 2

    Topics: Alprostadil; Apomorphine; Dopamine Agonists; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents

2003
Oral drug treatment of erectile dysfunction.
    International journal of impotence research, 2003, Volume: 15 Suppl 7

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Apomorphine; Carbolines; Cyclic Nucleotide Phosphodiesterases, Type 5; Erectile Dysfunction; Humans; Imidazoles; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride

2003
Intranasal apomorphine. Nastech Pharmaceutical.
    IDrugs : the investigational drugs journal, 2004, Volume: 7, Issue:5

    Topics: Administration, Intranasal; Animals; Apomorphine; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Contraindications; Dopamine Agonists; Erectile Dysfunction; Female; Humans; Male; Sexual Dysfunctions, Psychological; Structure-Activity Relationship

2004
Emerging oral drugs for erectile dysfunction.
    Expert opinion on emerging drugs, 2004, Volume: 9, Issue:1

    Topics: Administration, Oral; Administration, Sublingual; Adult; Aged; Apomorphine; Carbolines; Comorbidity; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dopamine Agonists; Double-Blind Method; Drug Interactions; Erectile Dysfunction; Humans; Imidazoles; Male; Middle Aged; Multicenter Studies as Topic; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Purines; Randomized Controlled Trials as Topic; Second Messenger Systems; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents

2004
Sexual dysfunction and diabetes.
    International journal of clinical practice, 2004, Volume: 58, Issue:4

    Topics: Alprostadil; Apomorphine; Diabetes Complications; Diabetes Mellitus; Erectile Dysfunction; Humans; Life Style; Male; Medical History Taking; Penile Prosthesis; Phosphodiesterase Inhibitors; Risk Factors; Self Administration; Testosterone; Vacuum

2004
Future options for combination therapy in the management of erectile dysfunction in older men.
    Drugs & aging, 2004, Volume: 21, Issue:9

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic alpha-Antagonists; Aged; Alprostadil; Animals; Apomorphine; Clinical Trials as Topic; Cyclic Nucleotide Phosphodiesterases, Type 5; Dopamine Agonists; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Testosterone

2004
New oral drugs for erectile dysfunction.
    Drug and therapeutics bulletin, 2004, Volume: 42, Issue:7

    Topics: Apomorphine; Carbolines; Dopamine Agonists; Erectile Dysfunction; Humans; Imidazoles; Male; Phosphodiesterase Inhibitors; Piperazines; Randomized Controlled Trials as Topic; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride

2004
New treatment options for erectile dysfunction in patients with diabetes mellitus.
    Drugs, 2004, Volume: 64, Issue:23

    Topics: Adult; Aged; Apomorphine; Diabetes Complications; Erectile Dysfunction; Half-Life; Humans; Male; Middle Aged; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Prevalence; Purines; Quality of Life; Randomized Controlled Trials as Topic; Sildenafil Citrate; Sulfones

2004
Pharmacotherapy of erectile dysfunction: focus on cardiovascular safety.
    Expert opinion on drug safety, 2005, Volume: 4, Issue:3

    Topics: Administration, Oral; Apomorphine; Blood Pressure; Cardiovascular Diseases; Contraindications; Dopamine Agonists; Drug Interactions; Erectile Dysfunction; Humans; Hypotension; Male; Nitric Oxide Donors; Patient Selection; Phosphodiesterase Inhibitors; Piperazines; Purines; Risk Assessment; Sildenafil Citrate; Sulfones

2005
A comparative review of the options for treatment of erectile dysfunction: which treatment for which patient?
    Drugs, 2005, Volume: 65, Issue:12

    Topics: Administration, Oral; Alprostadil; Apomorphine; Carbolines; Constriction; Contraindications; Dopamine Agonists; Drug Combinations; Enzyme Inhibitors; Erectile Dysfunction; Humans; Imidazoles; Male; Papaverine; Patient Satisfaction; Penile Prosthesis; Penis; Phentolamine; Phosphodiesterase Inhibitors; Piperazines; Purines; Regional Blood Flow; Sildenafil Citrate; Sulfones; Tadalafil; Treatment Failure; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents

2005
[Pharmacotherapy for erectile dysfunction].
    Zhonghua nan ke xue = National journal of andrology, 2005, Volume: 11, Issue:8

    Topics: Animals; Apomorphine; Erectile Dysfunction; Humans; Male; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Sildenafil Citrate; Sulfones; Yohimbine

2005
Available and future treatments for erectile dysfunction.
    Clinical cornerstone, 2005, Volume: 7, Issue:1

    Topics: Apomorphine; Erectile Dysfunction; Humans; Male; Phentolamine; Phosphodiesterase Inhibitors; Testosterone; Yohimbine

2005
Central nervous system agents in the treatment of erectile dysfunction.
    The Urologic clinics of North America, 2005, Volume: 32, Issue:4

    Topics: Apomorphine; Central Nervous System Agents; Clinical Trials as Topic; Dopamine Agonists; Erectile Dysfunction; Humans; Male

2005
A comparative review of apomorphine formulations for erectile dysfunction : recommendations for use in the elderly.
    Drugs & aging, 2006, Volume: 23, Issue:4

    Topics: Aged; Apomorphine; Dosage Forms; Dose-Response Relationship, Drug; Drug Administration Routes; Erectile Dysfunction; Humans; Male

2006
Treatment of erectile dysfunction in multiple sclerosis.
    Expert review of neurotherapeutics, 2006, Volume: 6, Issue:6

    Topics: Alprostadil; Apomorphine; Dopamine Agents; Erectile Dysfunction; Humans; Male; Multiple Sclerosis; Phosphodiesterase Inhibitors; Psychotherapy; Vasodilator Agents

2006
Erectile dysfunction.
    Clinical evidence, 2006, Issue:15

    Topics: Adult; Alprostadil; Apomorphine; Carbolines; Erectile Dysfunction; Humans; Imidazoles; Male; Penile Erection; Penile Prosthesis; Piperazines; Purines; Sex Counseling; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Yohimbine

2006
[Apomorphine and erectile dysfunction].
    Zhonghua nan ke xue = National journal of andrology, 2007, Volume: 13, Issue:9

    Topics: Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Penile Erection

2007
Centrally acting mechanisms for the treatment of male sexual dysfunction.
    The Urologic clinics of North America, 2007, Volume: 34, Issue:4

    Topics: alpha-MSH; Animals; Apomorphine; Autonomic Nervous System; Dopamine; Dopamine Agonists; Erectile Dysfunction; Growth Hormone-Releasing Hormone; Humans; Male; Melanocortins; Muscle, Smooth; Nitric Oxide; Norepinephrine; Opioid Peptides; Penile Erection; Peptides, Cyclic; Phosphodiesterase Inhibitors; Serotonin; Treatment Outcome

2007
[Treatment per os of disorders of erection].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1997, Volume: 7, Issue:1

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Antidepressive Agents, Second-Generation; Apomorphine; Cyclic GMP; Dopamine Agonists; Enzyme Inhibitors; Erectile Dysfunction; Humans; Male; Phentolamine; Piperazines; Purines; Sildenafil Citrate; Sulfones; Trazodone; Yohimbine

1997
Pharmacological treatment of erectile dysfunction.
    Current opinion in urology, 1999, Volume: 9, Issue:6

    Topics: Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Muscle Relaxation; Papaverine; Phentolamine; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents

1999
[Oral therapy of erectile dysfunction].
    Wiener medizinische Wochenschrift (1946), 2000, Volume: 150, Issue:1-2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Phentolamine; Phosphodiesterase Inhibitors; Piperazines; Purines; Selective Serotonin Reuptake Inhibitors; Sildenafil Citrate; Sulfones; Trazodone; Yohimbine

2000
Apomorphine: an update of clinical trial results.
    International journal of impotence research, 2000, Volume: 12 Suppl 4

    Topics: Adolescent; Adult; Aged; Apomorphine; Clinical Trials, Phase III as Topic; Coitus; Cross-Over Studies; Dopamine Agonists; Dose-Response Relationship, Drug; Double-Blind Method; Erectile Dysfunction; Humans; Male; Middle Aged; Nausea; Penile Erection; Research Design; Safety; Time Factors; Treatment Outcome

2000
New treatment for erectile dysfunction.
    Current psychiatry reports, 2000, Volume: 2, Issue:3

    Topics: Apomorphine; Clinical Trials as Topic; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents

2000
Erectile dysfunction.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:6

    Topics: Adrenergic alpha-Antagonists; Alprostadil; Androgens; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Prevalence; Vasodilator Agents

2001
Pharmacology of erectile function and dysfunction.
    The Urologic clinics of North America, 2001, Volume: 28, Issue:2

    Topics: Animals; Apomorphine; Dopamine Agonists; Endothelins; Erectile Dysfunction; Humans; Male; Penile Erection; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Endothelin; Selective Serotonin Reuptake Inhibitors; Trazodone; Vasoactive Intestinal Peptide

2001
Oral drug therapy for erectile dysfunction.
    The Urologic clinics of North America, 2001, Volume: 28, Issue:2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Oral; Apomorphine; Cardiovascular System; Contraindications; Coronary Disease; Cyclic Nucleotide Phosphodiesterases, Type 5; Dopamine Agonists; Erectile Dysfunction; Heart; Humans; Male; Phosphodiesterase Inhibitors; Piperazines; Prostatectomy; Purines; Sildenafil Citrate; Spinal Cord Injuries; Sulfones

2001
Apomorphine to Uprima: the development of a practical erectogenic drug: a personal perspective.
    International journal of impotence research, 2001, Volume: 13 Suppl 3

    Topics: Administration, Oral; Animals; Apomorphine; Canada; Clinical Trials, Phase IV as Topic; Dopamine Agonists; Drug Approval; Erectile Dysfunction; History, 19th Century; History, 20th Century; Humans; Male; Penile Erection; Technology, Pharmaceutical

2001
Characterising the benefit of apomorphine SL (Uprima) as an optimised treatment for representative populations with erectile dysfunction.
    International journal of impotence research, 2001, Volume: 13 Suppl 3

    Topics: Administration, Sublingual; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male

2001
Safety and tolerability of apomorphine SL (Uprima).
    International journal of impotence research, 2001, Volume: 13 Suppl 3

    Topics: Administration, Sublingual; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Safety

2001
New oral agents for erectile dysfunction: what is changing in our practice?
    Asian journal of andrology, 2001, Volume: 3, Issue:3

    Topics: Administration, Oral; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Phosphodiesterase Inhibitors; Practice Patterns, Physicians'; Urology

2001
Current treatments and emerging therapeutic approaches in male erectile dysfunction.
    BJU international, 2001, Volume: 88 Suppl 3

    Topics: Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Erectile Dysfunction; Humans; Hypogonadism; Imidazoles; Male; Penile Implantation; Physical Therapy Modalities; Piperazines; Psychotherapy; Purines; Sildenafil Citrate; Sulfones; Testosterone; Triazines; Vacuum; Vardenafil Dihydrochloride; Vascular Surgical Procedures; Vasodilator Agents; Yohimbine

2001
The pharmacology and clinical pharmacokinetics of apomorphine SL.
    BJU international, 2001, Volume: 88 Suppl 3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apomorphine; Chemical and Drug Induced Liver Injury; Dopamine Agonists; Erectile Dysfunction; Humans; Kidney Diseases; Male; Middle Aged

2001
Efficacy of apomorphine SL in erectile dysfunction.
    BJU international, 2001, Volume: 88 Suppl 3

    Topics: Adult; Apomorphine; Clinical Trials as Topic; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Quality of Life; Time Factors; Treatment Outcome

2001
Mode of action of a new oral treatment for erectile dysfunction: apomorphine SL.
    BJU international, 2001, Volume: 88 Suppl 3

    Topics: Administration, Oral; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male

2001
Safety and tolerability of apomorphine SL in patients with erectile dysfunction.
    BJU international, 2001, Volume: 88 Suppl 3

    Topics: Adult; Aged; Alcohol Drinking; Antiemetics; Apomorphine; Cardiovascular Agents; Dopamine Agonists; Drug Interactions; Electrocardiography; Erectile Dysfunction; Humans; Male; Middle Aged

2001
The role of apomorphine SL in the treatment of male erectile dysfunction.
    BJU international, 2001, Volume: 88 Suppl 3

    Topics: Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male

2001
Oral treatment of erectile dysfunction with apomorphine SL.
    Urologia internationalis, 2001, Volume: 67, Issue:4

    Topics: Administration, Oral; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Heart Diseases; Humans; Male; Penile Erection; Risk Factors

2001
Dopamine and male sexual function.
    European urology, 2001, Volume: 40, Issue:6

    Topics: Animals; Apomorphine; Dopamine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Nucleus Accumbens; Paraventricular Hypothalamic Nucleus; Penile Erection; Preoptic Area; Sexual Behavior, Animal; Spinal Cord

2001
Sublingual apomorphine for the treatment of erectile dysfunction.
    Expert opinion on investigational drugs, 2002, Volume: 11, Issue:2

    Topics: Administration, Sublingual; Apomorphine; Clinical Trials as Topic; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Penile Erection; Time Factors

2002
Apomorphine SL (Uprima): preclinical and clinical experiences learned from the first central nervous system-acting ED drug.
    International journal of impotence research, 2002, Volume: 14 Suppl 1

    Topics: Animals; Apomorphine; Dopamine Agents; Erectile Dysfunction; Humans; Male; Penile Erection

2002
Economic aspects of medical erectile dysfunction therapies.
    Expert opinion on pharmacotherapy, 2002, Volume: 3, Issue:3

    Topics: Apomorphine; Cost-Benefit Analysis; Dopamine Agonists; Erectile Dysfunction; Humans; Injections; Male; Penis; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Urethra

2002

Trials

26 trial(s) available for apomorphine and Impotence

ArticleYear
[Efficacy of compound Xuanju Capsule combined with apomorphine hydrochloride on erectile dysfunction].
    Zhonghua nan ke xue = National journal of andrology, 2012, Volume: 18, Issue:12

    Topics: Adult; Aged; Apomorphine; Capsules; Drug Therapy, Combination; Drugs, Chinese Herbal; Erectile Dysfunction; Humans; Male; Middle Aged; Phytotherapy; Treatment Outcome; Young Adult

2012
Comparative cross-over study of sildenafil and apomorphine for treating erectile dysfunction.
    BJU international, 2008, Volume: 102, Issue:7

    Topics: Adult; Aged; Apomorphine; Coitus; Cross-Over Studies; Erectile Dysfunction; Humans; Male; Middle Aged; Patient Satisfaction; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Prospective Studies; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome

2008
An open-label, randomized, flexible-dose, crossover study to assess the comparative efficacy and safety of sildenafil citrate and apomorphine hydrochloride in men with erectile dysfunction.
    Urologia internationalis, 2008, Volume: 81, Issue:4

    Topics: Adult; Apomorphine; Cross-Over Studies; Dopamine; Erectile Dysfunction; Humans; Male; Middle Aged; Piperazines; Purines; Research Design; Safety; Sildenafil Citrate; Sulfones; Surveys and Questionnaires; Time Factors; Vasodilator Agents

2008
Inhalation device allows novel administration of apomorphine in men with erectile dysfunction-efficacy and safety findings.
    The journal of sexual medicine, 2010, Volume: 7, Issue:4 Pt 1

    Topics: Administration, Inhalation; Adult; Aged; Apomorphine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Erectile Dysfunction; Humans; Male; Middle Aged; Penile Erection; Powders; Sexual Behavior; Treatment Outcome

2010
Brain activation patterns during video sexual stimulation following the administration of apomorphine: results of a placebo-controlled study.
    European urology, 2003, Volume: 43, Issue:4

    Topics: Administration, Sublingual; Aged; Apomorphine; Arousal; Brain; Brain Mapping; Double-Blind Method; Erectile Dysfunction; Erotica; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Penile Erection; Reference Values; Sensitivity and Specificity; Video Recording

2003
Effects of visual sexual stimuli and apomorphine SL on cerebral activity in men with erectile dysfunction.
    European urology, 2003, Volume: 43, Issue:4

    Topics: Adult; Apomorphine; Arousal; Central Nervous System; Dopamine Agonists; Erectile Dysfunction; Erotica; Humans; Male; Penile Erection; Probability; Reference Values; Regional Blood Flow; Sensitivity and Specificity; Tomography, Emission-Computed

2003
Apomorphine-induced brain modulation during sexual stimulation: a new look at central phenomena related to erectile dysfunction.
    International journal of impotence research, 2003, Volume: 15, Issue:3

    Topics: Adult; Apomorphine; Brain; Case-Control Studies; Coitus; Cross-Over Studies; Dopamine Agonists; Double-Blind Method; Erectile Dysfunction; Frontal Lobe; Humans; Limbic System; Magnetic Resonance Imaging; Male; Placebos; Psychophysiologic Disorders

2003
Efficacy and safety of daily intake of apomorphine SL in men affected by erectile dysfunction and mild hyperprolactinemia: a prospective, open-label, pilot study.
    Urology, 2003, Volume: 62, Issue:5

    Topics: Adult; Apomorphine; Delayed-Action Preparations; Drug Administration Schedule; Erectile Dysfunction; Follicle Stimulating Hormone; Humans; Hyperprolactinemia; Luteinizing Hormone; Male; Middle Aged; Penile Erection; Pilot Projects; Prospective Studies; Safety; Testosterone; Treatment Outcome; Ultrasonography

2003
Clinical experience with apomorphine hydrochloride: the first 107 patients.
    The Journal of urology, 2003, Volume: 170, Issue:6 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Apomorphine; Erectile Dysfunction; Humans; Male; Middle Aged

2003
A comparative, crossover study of the efficacy and safety of sildenafil and apomorphine in men with evidence of arteriogenic erectile dysfunction.
    International journal of impotence research, 2004, Volume: 16, Issue:1

    Topics: Apomorphine; Arteries; Cross-Over Studies; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Middle Aged; Patient Satisfaction; Piperazines; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome; Vascular Diseases; Vasodilator Agents

2004
An open-label, randomized, flexible-dose, crossover study to assess the comparative efficacy and safety of sildenafil citrate and apomorphine hydrochloride in men with erectile dysfunction.
    BJU international, 2004, Volume: 93, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Apomorphine; Cross-Over Studies; Erectile Dysfunction; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome; Vasodilator Agents

2004
Efficacy of apomorphine and sildenafil in men with nonarteriogenic erectile dysfunction. A comparative crossover study.
    Andrologia, 2004, Volume: 36, Issue:3

    Topics: Apomorphine; Cross-Over Studies; Erectile Dysfunction; Humans; Male; Middle Aged; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Prospective Studies; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome

2004
Prospective, randomized, crossover comparison of sublingual apomorphine (3 mg) with oral sildenafil (50 mg) for male erectile dysfunction.
    The Journal of urology, 2004, Volume: 172, Issue:6 Pt 1

    Topics: Administration, Oral; Administration, Sublingual; Adult; Aged; Apomorphine; Cross-Over Studies; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Piperazines; Prospective Studies; Purines; Sildenafil Citrate; Sulfones

2004
Sexual dysfunction in patients under dialytic treatment.
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2006, Volume: 58, Issue:2

    Topics: Adult; Aged; Apomorphine; Erectile Dysfunction; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Piperazines; Prospective Studies; Purines; Renal Dialysis; Sildenafil Citrate; Sulfones

2006
Comparative trial of treatment satisfaction, efficacy and tolerability of sildenafil versus apomorphine in erectile dysfunction--an open, randomized cross-over study with flexible dosing.
    European journal of medical research, 2007, Feb-26, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Apomorphine; Coitus; Cross-Over Studies; Erectile Dysfunction; Humans; Male; Middle Aged; Orgasm; Patient Satisfaction; Penile Erection; Piperazines; Purines; Sexual Partners; Sildenafil Citrate; Sulfones; Surveys and Questionnaires; Treatment Outcome

2007
[Intraurethrally applicated alprostadil for the treatment of organic erectile dysfunction in practice: a multicenter clinical monitoring study (noninterventional investigation)].
    Arzneimittel-Forschung, 2007, Volume: 57, Issue:6

    Topics: Aged; Aged, 80 and over; Alprostadil; Apomorphine; Body Mass Index; Dopamine Agonists; Double-Blind Method; Drug Therapy, Combination; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Orgasm; Penile Erection; Phosphodiesterase Inhibitors; Postoperative Complications; Quality of Life; Urethra; Vasodilator Agents

2007
Effect of blood sampling on apomorphine-induced penile tumescence in erectile impotence: a case report.
    Journal of psychiatry & neuroscience : JPN, 1995, Volume: 20, Issue:3

    Topics: Apomorphine; Erectile Dysfunction; Humans; Hyperprolactinemia; Male; Middle Aged; Penile Erection; Testosterone

1995
Recovery of erectile function by the oral administration of apomorphine.
    Urology, 1995, Volume: 45, Issue:2

    Topics: Administration, Sublingual; Adult; Aged; Apomorphine; Erectile Dysfunction; Humans; Male; Middle Aged; Penile Erection

1995
Efficacy and safety of fixed-dose and dose-optimization regimens of sublingual apomorphine versus placebo in men with erectile dysfunction. The Apomorphine Study Group.
    Urology, 2000, Volume: 56, Issue:1

    Topics: Administration, Sublingual; Adult; Aged; Apomorphine; Dopamine Agonists; Double-Blind Method; Erectile Dysfunction; Humans; Male; Middle Aged

2000
Double-blind, crossover comparison of 3 mg apomorphine SL with placebo and with 4 mg apomorphine SL in male erectile dysfunction.
    European urology, 2001, Volume: 39, Issue:5

    Topics: Administration, Sublingual; Adult; Aged; Apomorphine; Coitus; Cross-Over Studies; Dopamine Agonists; Double-Blind Method; Erectile Dysfunction; Humans; Male; Middle Aged

2001
An open-label, uncontrolled dose-optimization study of sublingual apomorphine in erectile dysfunction.
    Clinical therapeutics, 2001, Volume: 23, Issue:8

    Topics: Administration, Sublingual; Adult; Aged; Apomorphine; Dopamine Agonists; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; Male; Middle Aged

2001
Cardiovascular safety of sublingual apomorphine in patients on stable doses of oral antihypertensive agents and nitrates.
    The American journal of cardiology, 2001, Oct-01, Volume: 88, Issue:7

    Topics: Administration, Sublingual; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Apomorphine; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Dopamine Agonists; Double-Blind Method; Electrocardiography, Ambulatory; Erectile Dysfunction; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrates; Treatment Outcome

2001
A European multicentre study to evaluate the tolerability of apomorphine sublingual administered in a forced dose-escalation regimen in patients with erectile dysfunction.
    BJU international, 2002, Volume: 89, Issue:4

    Topics: Administration, Sublingual; Adolescent; Adult; Aged; Apomorphine; Dopamine Agonists; Dose-Response Relationship, Drug; Double-Blind Method; Erectile Dysfunction; Europe; Humans; Male; Middle Aged; Tablets; Treatment Outcome

2002
Combination therapy for erectile dysfunction: a randomized, double blind, unblinded active-controlled, cross-over study of the pharmacodynamics and safety of combined oral formulations of apomorphine hydrochloride, phentolamine mesylate and papaverine hyd
    International journal of impotence research, 2002, Volume: 14, Issue:1

    Topics: Adrenergic alpha-Antagonists; Apomorphine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Erectile Dysfunction; Humans; Male; Papaverine; Phentolamine; Piperazines; Purines; Safety; Severity of Illness Index; Sildenafil Citrate; Sulfones; Treatment Outcome; Vasodilator Agents

2002
Apomorphine: clinical studies on erectile impotence and yawning.
    Progress in neuro-psychopharmacology & biological psychiatry, 1989, Volume: 13, Issue:3-4

    Topics: Adult; Apomorphine; Diabetes Mellitus, Type 2; Erectile Dysfunction; Humans; Lithium; Male; Middle Aged; Penis; Yawning

1989
Apomorphine-induced penile tumescence in impotent patients--preliminary findings.
    Progress in neuro-psychopharmacology & biological psychiatry, 1987, Volume: 11, Issue:2-3

    Topics: Adult; Apomorphine; Bromocriptine; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; Male; Middle Aged; Penile Erection; Prognosis; Prolactin

1987

Other Studies

56 other study(ies) available for apomorphine and Impotence

ArticleYear
Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction.
    Journal of medicinal chemistry, 2004, Jul-15, Volume: 47, Issue:15

    Topics: Animals; Benzimidazoles; Cell Line; Erectile Dysfunction; Ferrets; Humans; Male; Penile Erection; Piperazines; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D4; Structure-Activity Relationship; Vomiting

2004
1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction.
    Journal of medicinal chemistry, 2006, Aug-24, Volume: 49, Issue:17

    Topics: Animals; Benzamides; Binding Sites; Cell Line; Crystallography, X-Ray; Disease Models, Animal; Drug Evaluation, Preclinical; Erectile Dysfunction; Ferrets; Humans; Male; Models, Molecular; Molecular Structure; Oximes; Piperazines; Rats; Rats, Wistar; Receptors, Dopamine D4; Stereoisomerism; Structure-Activity Relationship

2006
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Action Potentials; Administration, Oral; Animals; Benzamides; Biological Availability; Cell Line; Cyclic N-Oxides; Dogs; Erectile Dysfunction; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Haplorhini; Humans; In Vitro Techniques; Male; Patch-Clamp Techniques; Purkinje Fibers; Rats; Receptors, Dopamine D4; Structure-Activity Relationship

2006
Dopamine D2 receptors in the nucleus accumbens modulate erectile function in a rat model of nonorganic erectile dysfunction.
    Andrology, 2022, Volume: 10, Issue:4

    Topics: Animals; Apomorphine; Dopamine; Erectile Dysfunction; Humans; Male; Nucleus Accumbens; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Sucrose; Tyrosine 3-Monooxygenase

2022
High-Salt Intake Reduces Apomorphine-Induced Penile Erection and Increases Neurally Mediated Contractile Responses of the Cavernosal Smooth Muscle in Rats.
    American journal of hypertension, 2019, 11-15, Volume: 32, Issue:12

    Topics: Animals; Apomorphine; Calcium Signaling; Electric Stimulation; Erectile Dysfunction; Male; Muscle Contraction; Muscle, Smooth; Penile Erection; Penis; Rats, Wistar; rho-Associated Kinases; Sodium Chloride, Dietary

2019
Changes in Male Rat Sexual Behavior and Brain Activity Revealed by Functional Magnetic Resonance Imaging in Response to Chronic Mild Stress.
    The journal of sexual medicine, 2018, Volume: 15, Issue:2

    Topics: Animals; Apomorphine; Brain; Depression; Disease Models, Animal; Erectile Dysfunction; Female; Magnetic Resonance Imaging; Male; Penile Erection; Rats; Rats, Wistar; Sexual Behavior

2018
Dopamine D2 receptors in the basolateral amygdala modulate erectile function in a rat model of nonorganic erectile dysfunction.
    Andrologia, 2019, Volume: 51, Issue:1

    Topics: Animals; Apomorphine; Basolateral Nuclear Complex; Disease Models, Animal; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Erectile Dysfunction; Male; Penile Erection; Rats; Rats, Wistar; Receptors, Dopamine D2; Sexual Behavior, Animal; Stress, Psychological

2019
Chromatographic analysis of some drugs employed in erectile dysfunction therapy: qualitative and quantitative studies using calixarene stationary phase.
    Journal of separation science, 2014, Volume: 37, Issue:20

    Topics: Apomorphine; Buffers; Calixarenes; Carbolines; Chromatography, High Pressure Liquid; Erectile Dysfunction; Humans; Hydrogen-Ion Concentration; Limit of Detection; Male; Pharmaceutical Preparations; Piperazines; Purines; Reproducibility of Results; Sildenafil Citrate; Sulfonamides; Tadalafil

2014
[Therapeutic efficacy of Bushengzhuyang Fang (Yangjing Capsule) on phytoestrogen-induced erectile dysfunction: an experimental study].
    Zhonghua nan ke xue = National journal of andrology, 2014, Volume: 20, Issue:12

    Topics: Animals; Apomorphine; Drugs, Chinese Herbal; Erectile Dysfunction; Humans; Isoflavones; Luteinizing Hormone; Male; Penile Erection; Penis; Phytoestrogens; Phytotherapy; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfonamides; Testosterone; Vasodilator Agents

2014
[Expressions of HO-2 and CO in the corpus cavernosum of castrated rats].
    Zhonghua nan ke xue = National journal of andrology, 2015, Volume: 21, Issue:5

    Topics: Animals; Apomorphine; Carbon Monoxide; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Molecular Chaperones; Orchiectomy; Penile Erection; Penis; Random Allocation; Rats; Rats, Sprague-Dawley

2015
[Expression of nNOS and ultrastructural changes in the penile tissue of rats with prolactinoma-induced erectile dysfunction].
    Zhonghua nan ke xue = National journal of andrology, 2015, Volume: 21, Issue:10

    Topics: Animals; Apomorphine; Carcinogens; Diethylstilbestrol; Erectile Dysfunction; Humans; Male; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type I; Organ Size; Penile Erection; Penis; Pituitary Neoplasms; Prolactin; Prolactinoma; Rats; Rats, Wistar; Testosterone

2015
Role of endothelin receptors and relationship with nitric oxide synthase in impaired erectile response in diabetic rats.
    Andrologia, 2017, Volume: 49, Issue:2

    Topics: Animals; Apomorphine; Bosentan; Diabetes Mellitus, Experimental; Dopamine Agonists; Endothelin Receptor Antagonists; Endothelin-1; Erectile Dysfunction; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Penile Erection; Penis; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Sulfonamides; Tumor Necrosis Factor-alpha

2017
[Erectile dysfunctions].
    Orvosi hetilap, 2009, Jan-18, Volume: 150, Issue:3

    Topics: Adrenergic alpha-Antagonists; Apomorphine; Diagnosis, Differential; Dopamine Agonists; Erectile Dysfunction; Humans; Impotence, Vasculogenic; Male; Penile Implantation; Phosphodiesterase Inhibitors; Risk Factors; Testosterone; Vascular Surgical Procedures; Yohimbine

2009
Erectile function restoration after repair of excised cavernous nerves by autologous vein graft in rats.
    The journal of sexual medicine, 2010, Volume: 7, Issue:10

    Topics: Animals; Apomorphine; Disease Models, Animal; Erectile Dysfunction; Male; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Transplantation, Autologous; Veins

2010
Morphological and functional evidence for the contribution of the pudendal artery in aging-induced erectile dysfunction.
    The journal of sexual medicine, 2010, Volume: 7, Issue:10

    Topics: Acetylcholine; Aging; Animals; Apomorphine; Arteries; Dose-Response Relationship, Drug; Erectile Dysfunction; Male; Penile Erection; Penis; Phenylephrine; Rats; Rats, Sprague-Dawley

2010
Evaluation and treatment of erectile dysfunction in the aging male: a mini-review.
    Gerontology, 2012, Volume: 58, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Apomorphine; Erectile Dysfunction; Female; Humans; Male; Middle Aged; Phosphodiesterase 5 Inhibitors; Plant Preparations; Prostheses and Implants; Vacuum

2012
[Erectile dysfunction].
    Ugeskrift for laeger, 2002, Oct-07, Volume: 164, Issue:41

    Topics: Adrenergic beta-Antagonists; Alprostadil; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Genetic Therapy; Humans; Impotence, Vasculogenic; Male; Penile Erection; Phosphodiesterase Inhibitors; Vasodilator Agents; Yohimbine

2002
Systemic apomorphine alters HPA axis responses to interleukin-1 beta administration but not sound stress.
    Psychoneuroendocrinology, 2003, Volume: 28, Issue:6

    Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Hypothalamo-Hypophyseal System; Immunohistochemistry; Interleukin-1; Male; Neural Pathways; Noise; Oncogene Proteins v-fos; Pituitary-Adrenal System; Rats; Rats, Wistar; Stress, Physiological; Stress, Psychological

2003
Evaluating dose regimens of apomorphine, an open-label study.
    International journal of impotence research, 2003, Volume: 15 Suppl 2

    Topics: Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Medical Records; Middle Aged; Patient Satisfaction; Thailand

2003
Coming attractions! New medications on the horizon for erectile dysfunction.
    Urologic nursing, 2003, Volume: 23, Issue:4

    Topics: Alprostadil; Apomorphine; Carbolines; Drug Approval; Erectile Dysfunction; Genetic Therapy; Global Health; Humans; Male; Phosphodiesterase Inhibitors; Tadalafil; United States; United States Food and Drug Administration

2003
[Drug therapy of erectile dysfunction--the current status].
    Der Urologe. Ausg. A, 2003, Volume: 42, Issue:10

    Topics: Administration, Oral; Administration, Topical; Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Penis; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Testosterone; Vasodilator Agents; Yohimbine

2003
Apomorphine sublingual as primary or secondary treatment for erectile dysfunction in patients with spinal cord injury.
    BJU international, 2004, Volume: 93, Issue:1

    Topics: Administration, Sublingual; Adult; Apomorphine; Dopamine Agonists; Electrophysiology; Erectile Dysfunction; Humans; Male; Middle Aged; Prospective Studies; Spinal Cord Injuries; Treatment Outcome; Urodynamics

2004
Nymphaea cults in ancient Egypt and the New World: a lesson in empirical pharmacology.
    Journal of the Royal Society of Medicine, 2004, Volume: 97, Issue:2

    Topics: Apomorphine; Egypt, Ancient; Erectile Dysfunction; Flowers; History, Ancient; Humans; Male; Medicine, Traditional; Mexico; Nymphaea; Phytotherapy

2004
A prospective evaluation of efficacy and compliance with a multistep treatment approach for erectile dysfunction in patients after non-nerve sparing radical prostatectomy.
    BJU international, 2005, Volume: 95, Issue:3

    Topics: Administration, Sublingual; Aged; Algorithms; Apomorphine; Erectile Dysfunction; Follow-Up Studies; Humans; Male; Patient Compliance; Penile Prosthesis; Piperazines; Postoperative Complications; Prospective Studies; Prostaglandins E; Prostatectomy; Prostatic Neoplasms; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome; Vacuum; Vasodilator Agents

2005
Pharmacotherapy for erectile dysfunction.
    The journal of sexual medicine, 2004, Volume: 1, Issue:2

    Topics: alpha-MSH; Apomorphine; Dopamine Agonists; Drug Therapy, Combination; Erectile Dysfunction; Humans; Isoquinolines; Male; Naltrexone; Naphthyridines; Neuroprotective Agents; Peptides, Cyclic; Phosphodiesterase Inhibitors; Selective Serotonin Reuptake Inhibitors; Sexual Behavior; Trazodone

2004
[Determination of apomorphine, sildenafil and alprostadil in medicines for erectile dysfunction by high performance liquid chromatography-mass spectrometry].
    Se pu = Chinese journal of chromatography, 2005, Volume: 23, Issue:6

    Topics: Alprostadil; Apomorphine; Chromatography, High Pressure Liquid; Dopamine Agonists; Drugs, Chinese Herbal; Erectile Dysfunction; Humans; Male; Mass Spectrometry; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones

2005
Examination of the safety and use of apomorphine prescribed in general practice in England as a treatment for erectile dysfunction.
    BJU international, 2006, Volume: 98, Issue:1

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Apomorphine; Cohort Studies; Dopamine Agonists; England; Erectile Dysfunction; Family Practice; Humans; Male; Middle Aged; Treatment Outcome

2006
Effects of chronic renal failure on the expression of connexin 43 in the rat's corpus cavernosum.
    Asian journal of andrology, 2008, Volume: 10, Issue:2

    Topics: Animals; Apomorphine; Blotting, Western; Connexin 43; Disease Models, Animal; Erectile Dysfunction; Gene Expression; Kidney Failure, Chronic; Male; Penile Erection; Penis; Rats; Rats, Sprague-Dawley

2008
Commentary on apomorphine versus sildenafil for erectile dysfunction.
    The Journal of urology, 2008, Volume: 179, Issue:5 Suppl

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome

2008
[Establishment of a rat model of diabetic erectile dysfunction].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2008, Volume: 28, Issue:4

    Topics: Animals; Apomorphine; Diabetes Mellitus, Experimental; Disease Models, Animal; Erectile Dysfunction; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin

2008
Apomorphine-induced penile erections in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 1998, Volume: 13, Issue:3

    Topics: Adult; Aged; Antiparkinson Agents; Apomorphine; Erectile Dysfunction; Humans; Injections, Subcutaneous; Male; Middle Aged; Parkinson Disease; Penile Erection

1998
Apomorphine (TAP holdings). 6a beta-aporphine-10,11-diol hydrochloride hemihydrate, apomorphine hydrochloride, spontane, Uprima.
    Drugs in R&D, 1999, Volume: 2, Issue:6

    Topics: Apomorphine; Clinical Trials, Phase III as Topic; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Placebos; Receptors, Dopamine D2

1999
FDA committee recommends approval for viagra rival.
    BMJ (Clinical research ed.), 2000, Apr-22, Volume: 320, Issue:7242

    Topics: Apomorphine; Dopamine Agonists; Drug Approval; Erectile Dysfunction; Humans; Male; United States; United States Food and Drug Administration

2000
Delayed testosterone replacement restores nitric oxide synthase-containing nerve fibres and the erectile response in rat penis.
    BJU international, 2000, Volume: 85, Issue:7

    Topics: Animals; Apomorphine; Castration; Erectile Dysfunction; Hormone Replacement Therapy; Male; Nerve Fibers; Nitric Oxide Synthase; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Testosterone

2000
Looking beyond Viagra. The 30 million American men with impotence problems may soon have two oral treatments to choose from. How do they compare?
    Newsweek, 2000, Apr-24, Volume: 135, Issue:17

    Topics: Apomorphine; Erectile Dysfunction; Humans; Male; Piperazines; Purines; Sildenafil Citrate; Sulfones

2000
[Erectile dysfunction: an update on new therapeutic options].
    Acta urologica Belgica, 2000, Volume: 68, Issue:2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aged; Apomorphine; Clinical Trials as Topic; Cyclic Nucleotide Phosphodiesterases, Type 5; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Nitric Oxide Donors; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Sildenafil Citrate; Sulfones

2000
Current concepts in erectile dysfunction.
    The American journal of managed care, 2000, Volume: 6, Issue:12 Suppl

    Topics: Administration, Oral; Adult; Aged; Algorithms; Apomorphine; Comorbidity; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Medical History Taking; Middle Aged; Penile Implantation; Phosphodiesterase Inhibitors; Physical Examination; Piperazines; Prostaglandins; Purines; Sildenafil Citrate; Sulfones; United States

2000
Clinical perspective on erectile dysfunction therapies.
    The American journal of managed care, 2000, Volume: 6, Issue:12 Suppl

    Topics: Adult; Aged; Apomorphine; Counseling; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Piperazines; Primary Health Care; Purines; Sexual Partners; Sildenafil Citrate; Sulfones

2000
Key issues from the clinical trials of apomorphine SL.
    World journal of urology, 2001, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Apomorphine; Clinical Trials as Topic; Erectile Dysfunction; Humans; Male; Middle Aged

2001
[Soon there will be potency pills for every need. What is the value of the new viagra competitors? (interview by Dr. Brigitte Moreano)].
    MMW Fortschritte der Medizin, 2001, Jun-21, Volume: 143, Issue:25

    Topics: Apomorphine; Erectile Dysfunction; Humans; Male; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome

2001
Apomorphine SL (Uprima): a new treatment for the management of erectile dysfunction.
    International journal of impotence research, 2001, Volume: 13 Suppl 3

    Topics: Administration, Sublingual; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male

2001
Competition for Viagra.
    Trends in pharmacological sciences, 2001, Volume: 22, Issue:8

    Topics: Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male

2001
[Erectile dysfunction. Help also for cardiac patients].
    MMW Fortschritte der Medizin, 2001, Oct-11, Volume: 143, Issue:41

    Topics: Apomorphine; Contraindications; Coronary Disease; Drug Interactions; Erectile Dysfunction; Humans; Male; Molsidomine; Nitrates; Piperazines; Purines; Sildenafil Citrate; Sulfones

2001
Erectile dysfunction occurs following substantia nigra lesions in the rat.
    International journal of impotence research, 2001, Volume: 13, Issue:5

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Diseases; Corpus Striatum; Dopamine; Dopamine Agonists; Electric Stimulation; Erectile Dysfunction; Male; Nervous System; Oxidopamine; Penile Erection; Penis; Pressure; Rats; Rats, Sprague-Dawley; Substantia Nigra

2001
Sequential administration enhances the effect of apomorphine SL in men with erectile dysfunction.
    International journal of impotence research, 2002, Volume: 14, Issue:1

    Topics: Administration, Sublingual; Apomorphine; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; Male; Randomized Controlled Trials as Topic; Retreatment

2002
[Hypertension and impotence. Which potency drug is the most appropriate here?].
    MMW Fortschritte der Medizin, 2002, Mar-07, Volume: 144, Issue:10

    Topics: Antihypertensive Agents; Apomorphine; Clinical Trials as Topic; Dopamine Agonists; Drug Interactions; Erectile Dysfunction; Humans; Hypertension; Male; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones

2002
Apomorphine as an alternative to sildenafil in Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 2002, Volume: 72, Issue:5

    Topics: Antiparkinson Agents; Apomorphine; Erectile Dysfunction; Humans; Injections, Subcutaneous; Male; Multiple System Atrophy; Parkinson Disease; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones

2002
Development of a rat model of sexual performance anxiety: effect of behavioural and pharmacological hyperadrenergic stimulation on APO-induced erections.
    International journal of impotence research, 2002, Volume: 14, Issue:2

    Topics: Animals; Anxiety Disorders; Apomorphine; Blood Pressure; Disease Models, Animal; Erectile Dysfunction; Heart Rate; Hemodynamics; Male; Methoxamine; Penile Erection; Rats; Rats, Wistar; Sexual Behavior, Animal; Stress, Psychological; Sympathetic Nervous System

2002
Sublingual apomorphine: new preparation. In erectile disorders: a narrow therapeutic margin.
    Prescrire international, 2002, Volume: 11, Issue:59

    Topics: Administration, Oral; Apomorphine; Clinical Trials as Topic; Dopamine Agonists; Erectile Dysfunction; Europe; Humans; Male; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Randomized Controlled Trials as Topic; Treatment Outcome; United States

2002
[Experiences with apomorphine SL in studies: tolerated therapy--even in problem patients].
    MMW Fortschritte der Medizin, 2002, May-06, Volume: Suppl 2

    Topics: Apomorphine; Clinical Trials as Topic; Drug Interactions; Erectile Dysfunction; Humans; Male; Patient Compliance

2002
[Erectile dysfunction. Breaking through the silence].
    MMW Fortschritte der Medizin, 2002, May-06, Volume: Suppl 2

    Topics: Apomorphine; Erectile Dysfunction; Humans; Male; Patient Education as Topic; Physician-Patient Relations; Treatment Outcome

2002
[Progress in therapy of erectile dysfunction. New orally administered drugs].
    Der Internist, 2002, Volume: 43, Issue:5

    Topics: Administration, Oral; Apomorphine; Clinical Trials as Topic; Erectile Dysfunction; Humans; Male; Phentolamine; Piperazines; Purines; Sildenafil Citrate; Sulfones; Trazodone; Treatment Outcome; Vasodilator Agents; Yohimbine

2002
Activation with (+/-)N-n-propyl-nor-apomorphine (NPA) of the male rat copulatory behavior.
    Experientia, 1979, May-15, Volume: 35, Issue:5

    Topics: Animals; Apomorphine; Copulation; Ejaculation; Erectile Dysfunction; Humans; Male; Rats; Stimulation, Chemical

1979
Effect of bromocriptine in patients with apomorphine-responsive erectile impotence: an open study.
    Journal of psychiatry & neuroscience : JPN, 1991, Volume: 16, Issue:5

    Topics: Adult; Apomorphine; Bromocriptine; Erectile Dysfunction; Humans; Male; Middle Aged

1991
Effect of apomorphine on penile tumescence in men with psychogenic impotence.
    The Journal of urology, 1991, Volume: 145, Issue:6

    Topics: Apomorphine; Double-Blind Method; Erectile Dysfunction; Humans; Male; Penile Erection

1991
[What can be expected of intracavernous injections?].
    Acta urologica Belgica, 1988, Volume: 56, Issue:2

    Topics: Adult; Aged; Apomorphine; Erectile Dysfunction; Humans; Injections; Injections, Subcutaneous; Male; Middle Aged; Moxisylyte; Papaverine; Penis; Vasodilator Agents

1988