Page last updated: 2024-08-17

apomorphine and Huntington Disease

apomorphine has been researched along with Huntington Disease in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199016 (41.03)18.7374
1990's13 (33.33)18.2507
2000's6 (15.38)29.6817
2010's4 (10.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Döbrössy, MD; Nikkhah, G; Pauly, MC; Piroth, T; Schackel, S1
Boll, MC; Campos-Arroyo, HD; Martínez-Lazcano, JC; Montes, S; Pérez-Neri, I; Pérez-Severiano, F; Ríos, C; Rodríguez-Páez, L; Sánchez-Mendoza, MA1
Bertolino, G; de Araujo, JE; Giorgetto, C; Kitabatake, TT; Silva, EC1
Armida, M; Calamandrei, G; Pezzola, A; Popoli, P; Potenza, RL; Tartaglione, AM1
Büchele, F; Döbrössy, M; Jiang, W; Nikkhah, G; Papazoglou, A1
Chu, K; Kang, L; Kim, M; Kim, SU; Lee, K; Lee, ST; Park, JE1
Carmichael, ST; Erickson, RI; Kornblum, HI; Oknaian, N; Simonian, S; Tatsukawa, KJ; Visnyei, K1
Chen, K; Connor, B; Hughes, SM; Vazey, EM1
Chu, K; Chung, H; Hwang, T; Kang, W; Kim, M; Lee, SE; Lee, ST; Park, JE; Song, J1
Barone, P; Bonavita, V; De Michele, G; Di Maio, L; Longo, K; Marconi, S; Vitale, C1
Caraceni, TA; Giovannini, P; Girotti, F; Parati, EA; Pederzoli, M1
Meltzer, HY1
Chase, TN; Denaro, A; Durso, R; Ruggeri, S; Tamminga, CA1
Bernardi, F; Corsini, GU; Gessa, GL; Marrosu, F1
Borlongan, CV; Cahill, DW; Randall, TS; Sanberg, PR1
Beal, MF; Brouillet, E; Dolan, R; Ferrante, RJ; Guyot, MC; Hantraye, P; Palfi, S; Peschanski, M1
Albanese, A; Bentivoglio, AR; Carretta, D; Cassetta, E; Tonali, P1
Conrad, JA; Kondoh, T; Low, WC; Pundt, LL1
Albanese, A; Colosimo, C; Merello, M1
Brouillet, E; Chibois, A; Condé, F; Dautry, C; Hantraye, P; Mittoux, V; Palfi, S; Peschanski, M; Riche, D1
Chopin, P; Colpaert, F; Marien, M; Martel, J1
Itakura, T; Nakai, K; Nakao, N; Ogura, M1
Donatelli, L1
Fibiger, HC; Mason, ST; Sanberg, PR1
Fibiger, HC; Mason, ST1
Sparber, SB; Tolosa, ES2
Tolosa, ES1
Cianchetti, C; Corsini, GU; Gessa, G; Mangoni, A; Masala, C; Onali, P1
Carlson, HE; Goodlett, RE; Hershman, JM; Levy, CL; Sowers, JR; Tourtellotte, WW1
Caraceni, T; Cocchi, D; Müller, EE; Panerai, AE; Parati, EA1
Fibiger, HC; Lehmann, J; Sanberg, PR1
Brownell, AL; Brownell, GL; Davenport, PD; Elmaleh, DR; Hantraye, P; Isacson, O; Madras, BK; Maziere, M; Riche, D; Schumacher, JM1
Hantraye, P; Isacson, O; Maziere, M; Riche, D2
Burton, S; Daya, S; Potgieter, B1
Hantraye, P; Isacson, O; Maziere, M; Riche, D; Sofroniew, MV1
Fernandez Pardal, MM; Micheli, F1
Holland, OB; Kennedy, B; Lake, CR; Murphy, D; Ziegler, MG1

Reviews

2 review(s) available for apomorphine and Huntington Disease

ArticleYear
Dopamine autoreceptor stimulation: clinical significance.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17 Suppl 1

    Topics: Apomorphine; Dopamine; Haloperidol; Humans; Huntington Disease; Mental Disorders; Neurons; Parkinson Disease; Piribedil; Receptors, Dopamine; Relaxation; Schizophrenia; Sleep; Tourette Syndrome

1982
Clinical usefulness of apomorphine in movement disorders.
    Clinical neuropharmacology, 1994, Volume: 17, Issue:3

    Topics: Antiparkinson Agents; Apomorphine; Dopamine Agonists; Dystonia; Humans; Huntington Disease; Movement Disorders; Neuroleptic Malignant Syndrome; Parkinson Disease

1994

Trials

6 trial(s) available for apomorphine and Huntington Disease

ArticleYear
Short-term continuous infusion of apomorphine hydrochloride for treatment of Huntington's chorea: A double blind, randomized cross-over trial.
    Movement disorders : official journal of the Movement Disorder Society, 2007, Volume: 22, Issue:16

    Topics: Adult; Antiparkinson Agents; Apomorphine; Cross-Over Studies; Depression; Double-Blind Method; Female; Humans; Huntington Disease; Infusions, Intravenous; Male; Middle Aged; Mood Disorders; Movement; Movement Disorders; Pilot Projects; Psychiatric Status Rating Scales

2007
Effects of DA agonist in Huntington disease hyperkinesia.
    Italian journal of neurological sciences, 1980, Volume: 1, Issue:3

    Topics: Adult; Apomorphine; Bromocriptine; Clinical Trials as Topic; Cyproheptadine; Diazepam; Female; Growth Hormone; Humans; Huntington Disease; Lisuride; Male; Middle Aged

1980
Acute challenge with apomorphine in Huntington's disease: a double-blind study.
    Clinical neuropharmacology, 1995, Volume: 18, Issue:5

    Topics: Adult; Apomorphine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Huntington Disease; Male; Middle Aged

1995
Studies on the anti-dyskinesia effect of apomorphine in man.
    Neurologia, neurocirugia, psiquiatria, 1976, Volume: 17, Issue:4

    Topics: Administration, Oral; Adult; Aged; Apomorphine; Clinical Trials as Topic; Drug Evaluation; Female; Haloperidol; Humans; Huntington Disease; Injections, Intravenous; Levodopa; Male; Middle Aged; Movement Disorders

1976
Apomorphine hydrochloride-induced improvement in Huntington's chorea: stimulation of dopamine receptor.
    Archives of neurology, 1978, Volume: 35, Issue:1

    Topics: Adult; Apomorphine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Haloperidol; Humans; Huntington Disease; Male; Middle Aged; Premedication; Receptors, Dopamine; Sulpiride

1978
Responses to lisuride in Meige's disease and chorea.
    Neurology, 1986, Volume: 36, Issue:3

    Topics: Aged; Apomorphine; Basal Ganglia Diseases; Clinical Trials as Topic; Ergolines; Female; Humans; Huntington Disease; Lisuride; Male; Meige Syndrome; Middle Aged

1986

Other Studies

31 other study(ies) available for apomorphine and Huntington Disease

ArticleYear
Donor age dependent graft development and recovery in a rat model of Huntington's disease: histological and behavioral analysis.
    Behavioural brain research, 2013, Nov-01, Volume: 256

    Topics: Age Factors; Animals; Apomorphine; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Female; Fetal Tissue Transplantation; Globus Pallidus; Huntington Disease; Motor Activity; Neurons; Quinolinic Acid; Rats, Sprague-Dawley; Recovery of Function

2013
Sub-chronic copper pretreatment reduces oxidative damage in an experimental Huntington's disease model.
    Biological trace element research, 2014, Volume: 162, Issue:1-3

    Topics: Animals; Apomorphine; Copper; Disease Models, Animal; gamma-Aminobutyric Acid; Huntington Disease; Lipid Peroxidation; Male; Oxidative Stress; Quinolinic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase

2014
Behavioural profile of Wistar rats with unilateral striatal lesion by quinolinic acid (animal model of Huntington disease) post-injection of apomorphine and exposure to static magnetic field.
    Experimental brain research, 2015, Volume: 233, Issue:5

    Topics: Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Functional Laterality; Huntington Disease; Magnetic Fields; Male; Motor Activity; Neurons; Quinolinic Acid; Rats; Rats, Wistar; Statistics as Topic

2015
Aberrant self-grooming as early marker of motor dysfunction in a rat model of Huntington's disease.
    Behavioural brain research, 2016, 10-15, Volume: 313

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Grooming; Huntington Disease; Male; Quinolinic Acid; Rats; Rats, Sprague-Dawley

2016
Ketamine anaesthesia interferes with the quinolinic acid-induced lesion in a rat model of Huntington's disease.
    Journal of neuroscience methods, 2009, May-15, Volume: 179, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Antiparkinson Agents; Apomorphine; Brain; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Huntington Disease; Isoflurane; Ketamine; Neurons; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley

2009
Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model.
    Neuroscience research, 2005, Volume: 52, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Cell Count; Cells, Cultured; Corpus Striatum; Disease Models, Animal; DNA-Binding Proteins; Dopamine and cAMP-Regulated Phosphoprotein 32; Drosophila Proteins; Endogenous Retroviruses; Functional Laterality; Galactosides; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Humans; Huntington Disease; Immunohistochemistry; Indoles; Infusions, Intravenous; Male; Motor Activity; Nerve Tissue Proteins; Neurons; Parvalbumins; Phosphoproteins; Phosphopyruvate Hydratase; Quinolinic Acid; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotarod Performance Test; Stem Cell Transplantation; Stem Cells; Time Factors

2005
Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion.
    Experimental neurology, 2006, Volume: 197, Issue:2

    Topics: Analysis of Variance; Animals; Apomorphine; Autoradiography; Behavior, Animal; Cell Count; Corpus Striatum; Disease Models, Animal; Embryo, Mammalian; Functional Laterality; Huntington Disease; Immunohistochemistry; Male; Motor Activity; Neurons; Positron-Emission Tomography; Quinolinic Acid; Radiography; Rats; Rats, Sprague-Dawley; Recovery of Function; Rotarod Performance Test; Stem Cell Transplantation; Stem Cells

2006
Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease.
    Experimental neurology, 2006, Volume: 199, Issue:2

    Topics: Analysis of Variance; Animals; Apomorphine; Brain Tissue Transplantation; Bromodeoxyuridine; Cell Count; Cell Differentiation; Disease Models, Animal; Dopamine Agonists; Huntington Disease; Immunohistochemistry; Male; Motor Activity; Neostriatum; Nerve Tissue Proteins; Neurons; Quinolinic Acid; Rats; Rats, Wistar; Stem Cell Transplantation; Time Factors; Transcription Factors; Tyrosine 3-Monooxygenase

2006
Human embryonic stem cell-derived neural precursor transplants attenuate apomorphine-induced rotational behavior in rats with unilateral quinolinic acid lesions.
    Neuroscience letters, 2007, Aug-09, Volume: 423, Issue:1

    Topics: Animals; Apomorphine; Cell Differentiation; Cell Line; Dopamine Agonists; Embryonic Stem Cells; Huntington Disease; Immunohistochemistry; Male; Microinjections; Neostriatum; Neurons; Neurotoxicity Syndromes; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Stromal Cells

2007
Plasma growth hormone and prolactin response to dopaminergic GABAmimetic and cholinergic stimulation in Huntington's disease.
    Neurology, 1983, Volume: 33, Issue:9

    Topics: Adult; Apomorphine; Arecoline; Dopamine; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Huntington Disease; Male; Muscimol; Oxazoles; Prolactin

1983
Neuropsychiatric implications of drugs acting on dopamine receptors: the effect of apomorphine.
    Progress in clinical and biological research, 1980, Volume: 39

    Topics: Animals; Apomorphine; Bipolar Disorder; Blood-Brain Barrier; Electroencephalography; Humans; Huntington Disease; Motor Activity; Parkinson Disease; Rats; Receptors, Dopamine; Schizophrenia; Sleep

1980
Asymmetrical motor behavior in rats with unilateral striatal excitotoxic lesions as revealed by the elevated body swing test.
    Brain research, 1995, Apr-03, Volume: 676, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Functional Laterality; Huntington Disease; Male; Motor Activity; Neurotoxins; Nitro Compounds; Propionates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Time Factors

1995
Chronic 3-nitropropionic acid treatment in baboons replicates the cognitive and motor deficits of Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, May-01, Volume: 16, Issue:9

    Topics: Animals; Apomorphine; Behavior, Animal; Brain; Cognition; Huntington Disease; Movement; Neurotoxins; Nitro Compounds; Papio; Propionates; Time Factors

1996
Transplantation of human fetal striatum into a rodent model of Huntington's disease ameliorates locomotor deficits.
    Neuroscience research, 1996, Volume: 24, Issue:4

    Topics: Acetylcholinesterase; Animals; Antiparkinson Agents; Apomorphine; Brain Tissue Transplantation; Coloring Agents; Disease Models, Animal; Fetal Tissue Transplantation; Histocytochemistry; Humans; Huntington Disease; Locomotion; Male; NADPH Dehydrogenase; Neostriatum; Phenothiazines; Rats; Rats, Sprague-Dawley; Rotation

1996
Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease.
    Nature medicine, 1998, Volume: 4, Issue:8

    Topics: Animals; Apomorphine; Brain Tissue Transplantation; Cognition; Corpus Striatum; Fetal Tissue Transplantation; Huntington Disease; Macaca fascicularis; Magnetic Resonance Imaging; Motor Activity; Nitro Compounds; Propionates; Transplantation, Homologous

1998
Neuroprotective effects of the alpha2-adrenoceptor antagonists, (+)-efaroxan and (+/-)-idazoxan, against quinolinic acid-induced lesions of the rat striatum.
    Experimental neurology, 1998, Volume: 154, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Behavior, Animal; Benzofurans; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Enzyme Activation; Huntington Disease; Idazoxan; Imidazoles; Male; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2

1998
Embryonic striatal grafts restore neuronal activity of the globus pallidus in a rodent model of Huntington's disease.
    Neuroscience, 1999, Volume: 88, Issue:2

    Topics: Action Potentials; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Electron Transport Complex IV; Electrophysiology; Fetal Tissue Transplantation; Globus Pallidus; Huntington Disease; Male; Neurons; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Rotation

1999
[The Cools and van Rossum theory and the pharmacology of Huntington's chorea].
    La Clinica terapeutica, 1977, Jun-15, Volume: 81, Issue:5

    Topics: Animals; Apomorphine; Brain; Cats; Dopamine; Dopamine beta-Hydroxylase; Drug Therapy, Combination; Ergonovine; Huntington Disease; Levodopa; Rats; Sulpiride; Tyrosine 3-Monooxygenase

1977
Kainic acid lesions of the striatum dissociate amphetamine and apomorphine stereotypy: similarities to Huntingdon's chorea.
    Science (New York, N.Y.), 1978, Jul-28, Volume: 201, Issue:4353

    Topics: Animals; Apomorphine; Behavior; Choline O-Acetyltransferase; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Glutamate Decarboxylase; Humans; Huntington Disease; Kainic Acid; Male; Nucleus Accumbens; Pyrrolidines; Rats; Stereotyped Behavior; Tyrosine 3-Monooxygenase

1978
Kainic acid lesions of the striatum: behavioural sequalae similar to Huntington's chorea.
    Brain research, 1978, Oct-27, Volume: 155, Issue:2

    Topics: Animals; Apomorphine; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamate Decarboxylase; Habituation, Psychophysiologic; Humans; Huntington Disease; Kainic Acid; Male; Motor Activity; Neurons; Nucleus Accumbens; Pyrrolidines; Rats; Stereotyped Behavior; Tyrosine 3-Monooxygenase

1978
Huntington chorea.
    Archives of neurology, 1977, Volume: 34, Issue:1

    Topics: Apomorphine; Bromocriptine; Humans; Huntington Disease

1977
Growth hormone and prolactin secretion in Huntington's disease.
    Life sciences, 1979, Feb-19, Volume: 24, Issue:8

    Topics: Adult; Aged; Apomorphine; Chlorpromazine; Female; Growth Hormone; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Time Factors

1979
Growth hormone hyperresponsiveness to dopaminergic stimulation in Huntington's chorea.
    Neuroendocrinology, 1979, Volume: 28, Issue:5

    Topics: Adult; Apomorphine; Bromocriptine; Female; Growth Hormone; Humans; Huntington Disease; Hypothalamo-Hypophyseal System; Levodopa; Male; Middle Aged; Receptors, Dopamine

1979
Sedative effects of apomorphine in an animal model of Huntington's disease.
    Archives of neurology, 1979, Volume: 36, Issue:6

    Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Humans; Huntington Disease; Kainic Acid; Male; Motor Activity; Rats; Receptors, Dopamine; Stereotyped Behavior

1979
A primate model of Huntington's disease: functional neural transplantation and CT-guided stereotactic procedures.
    Cell transplantation, 1992, Volume: 1, Issue:4

    Topics: Animals; Apomorphine; Brain Tissue Transplantation; Carbon Radioisotopes; Caudate Nucleus; Cocaine; Deoxyglucose; Female; Fetal Tissue Transplantation; Fluorodeoxyglucose F18; Glucose; Graft Survival; Huntington Disease; Ibotenic Acid; Male; Motor Activity; Neurotoxins; Papio; Putamen; Quinolinic Acid; Rats; Stereotaxic Techniques; Tomography, Emission-Computed; Tomography, X-Ray Computed; Transplantation, Heterologous

1992
Intrastriatal transplantation of cross-species fetal striatal cells reduces abnormal movements in a primate model of Huntington disease.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, May-01, Volume: 89, Issue:9

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Fetus; Huntington Disease; Immunosuppression Therapy; Papio; Regression Analysis; Transplantation, Heterologous

1992
Melatonin modulates apomorphine-induced rotational behaviour.
    Experientia, 1991, May-15, Volume: 47, Issue:5

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Huntington Disease; Hydroxydopamines; Male; Melatonin; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains

1991
A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon.
    Experimental neurology, 1990, Volume: 108, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Diseases; Caudate Nucleus; Disease Models, Animal; Dystonia; Female; Huntington Disease; Ibotenic Acid; Male; Motor Activity; Movement; Papio; Putamen

1990
Apomorphine-induced dyskinesias after excitotoxic caudate-putamen lesions and the effects of neural transplantation in non-human primates.
    Progress in brain research, 1990, Volume: 82

    Topics: Animals; Apomorphine; Brain Tissue Transplantation; Caudate Nucleus; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Fetal Tissue Transplantation; Huntington Disease; Ibotenic Acid; Male; Papio; Putamen; Rats; Species Specificity; Transplantation, Heterologous

1990
The effects of dopamine agonists on human cardiovascular and sympathetic nervous systems.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:4

    Topics: Adult; Aged; Apomorphine; Blood Pressure; Bromocriptine; Cardiovascular System; Catecholamines; Dopamine; Dopamine beta-Hydroxylase; Female; Heart Rate; Hemodynamics; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Parkinson Disease; Pulse; Sympathetic Nervous System

1985
Apomorphine in Huntington's chorea: clinical observations and theoretical considerations.
    Life sciences, 1974, Oct-01, Volume: 15, Issue:7

    Topics: Adult; Aged; Apomorphine; Dopamine; Female; Humans; Huntington Disease; Hyperkinesis; Male; Middle Aged; Receptors, Dopamine

1974