apomorphine has been researched along with Drug Withdrawal Symptoms in 121 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 78 (64.46) | 18.7374 |
1990's | 27 (22.31) | 18.2507 |
2000's | 9 (7.44) | 29.6817 |
2010's | 6 (4.96) | 24.3611 |
2020's | 1 (0.83) | 2.80 |
Authors | Studies |
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Mendes, A; Oliveira, V; Videira, G | 1 |
Castrioto, A; Cavallieri, F; Fraix, V; Krack, P; Meoni, S; Moro, E | 1 |
Cui, C; Hu, L; Li, Y; Sun, L | 1 |
Kinfe, TM; Slotty, PJ; Vesper, J; Wille, C | 1 |
Cousin, MA; Ebbert, JO; Klee, EW; Morales-Rosado, JA | 1 |
Callegaro-Filho, D; Carvalho, RC; Frussa-Filho, R; Fukushiro, DF; Helfer, DC; Sanday, L; Silva, RH; Trombin, TF; Zanlorenci, LH | 1 |
San Luciano, M; Saunders-Pullman, R | 1 |
Erikh, I; Schlesinger, I; Zaaroor, M | 1 |
Gewirtz, JC; Radke, AK | 1 |
Frussa-Filho, R; Palermo-Neto, J; Perry, JC; Tufik, S; Vital, MA | 1 |
Budde, H; Karow, AC; Schmidt, LG; Smolka, MN | 1 |
Farley, CM; Hernandez, RM; McDougall, SA; Reichel, CM | 1 |
Clow, A; Jenner, P; Marsden, CD; Theodorou, A | 2 |
Glassman, HN; Glassman, RB | 1 |
Black, RF; Hoffman, PL; Tabakoff, B | 1 |
Lapierre, YD; Rastogi, RB; Rastogi, SK; Singhal, RL | 1 |
Ackenheil, M; Albus, M; May, G; Müller-Spahn, F; Naber, D; Welter, D; Zander, K | 1 |
Dibner, MD; Melchior, C; Molinoff, PB; Rabin, RA; Wolfe, BB; Zahniser, NR | 1 |
Fage, D; Scatton, B | 1 |
Bernardi, MM; Palermo-Neto, J | 2 |
Gamble, SJ; Waddington, JL | 1 |
Bailey, R; Crisp, E; Jackson, DM; Jenkins, O | 1 |
Schmidt, L | 1 |
Baggio, G; Ferrari, F | 1 |
Dall'Olio, R; Gandolfi, O; Montanaro, N; Vaccheri, A | 1 |
Carey, RJ; De Veaugh-Geiss, J; Devanand, DP | 1 |
Cools, AR | 1 |
Mayne, DG | 1 |
Borison, RL; Diamond, BI; Gordon, JH | 1 |
Roth, RH; Wheeler, SC | 1 |
Diamond, BI; Gordon, JH | 1 |
Burov, IuV; Viglinskaia, IV | 1 |
Arnerić, SP; Flynn, JR; Long, JP; Verimer, T; Walsh, BJ | 1 |
Anokhina, IP; Ivanets, NN; Morozov, GV | 1 |
Diana, M; Gessa, GL; Muntoni, AL; Pistis, M | 1 |
Dettling, M; Dufeu, P; Gräf, KJ; Heinz, A; Rommelspacher, H; Schmidt, LG | 1 |
Antkiewicz-Michaluk, L; Michaluk, J; Romańska, I; Vetulani, J | 1 |
Lipska, BK; Weinberger, DR | 1 |
Lucki, I; McGonigle, P; Neisewander, JL | 1 |
Caron, MG; Ellinwood, EH; Joyner, CM; King, GR; Lee, TH; Silvia, C; Xue, Z | 1 |
Fernandez, W; Lees, AJ; Turjanski, N | 1 |
Bergamasco, B; Delsedime, M; Ferrero, B; Giangrandi, C; Priano, L; Rizzone, M; Scarzella, L | 1 |
Antkiewicz-Michaluk, L; Karolewicz, B; Michaluk, J; Vetulani, J | 1 |
Boening, J; Davids, E; Jakob, F; Thome, J; Weijers, G; Wiesbeck, GA; Wodarz, N | 1 |
Ellinwood, EH; Gao, WY; Lee, TH | 1 |
Capasso, A; Sorrentino, L | 1 |
Abílio, VC; Bergamo, M; Frussa-Filho, R; Palermo-Neto, J | 1 |
Cools, AR; Dirksen, R; Ellenbroek, B; van Egmond, J | 1 |
Dettling, M; Dufeu, P; Finckh, U; Giraldo-Velasquez, M; Gräf, KJ; Harms, H; Heinz, A; Kuhn, S; Otto, G; Pelz, J; Rolfs, A; Rommelspacher, H; Sander, T; Schmidt, LG | 1 |
el-Kadi, AO; Sharif, SI | 1 |
Frussa-Filho, R; Palermo-Neto, J; Vital, MB | 1 |
Davidson, C; Ellinwood, EH; Gao, WY; Lee, TH | 1 |
Farzin, D | 1 |
Aston-Jones, G; Druhan, JP; Walters, CL | 2 |
Gross, JP; Wiesbeck, GA | 1 |
Hoehe, MR; Rommelspacher, H; Samochowiec, J; Schmidt, LG; Smolka, M | 1 |
Dunai-Kovács, Z; Székely, JI | 1 |
Costall, B; Naylor, RJ; Owen, RT | 1 |
Jacob, JJ; Tremblay, EC | 1 |
Jenner, P; Marsden, CD; Pycock, C | 1 |
Collier, HO; Francis, DL; McDonald-Gibson, WJ; Roy, AC; Saeed, SA | 1 |
Lal, H | 1 |
Choma, P; Puri, SK; Volicer, L | 1 |
Bläsig, J; Herz, A; Laschka, E; Schulz, R | 1 |
Gianutsos, G; Lal, H; Puri, SK | 1 |
Chau-Pham, T; Dewey, WL; Martin, BR; Prnage, AJ | 1 |
Hitzemann, BA; Hitzemann, RJ; Loh, HH; Sampath-Khanna, S; Tseng, LF | 1 |
Brown, G; Brown, W; Drawbaugh, R; Hynes, M; Lal, H | 1 |
Ary, M; Cox, B; Lomax, P | 3 |
Halliwell, JV; Kumar, R | 1 |
Cox, RD; Glick, SD | 1 |
Lal, S; Sourkes, TL; Symes, AL; Tsang, D; Young, SN | 1 |
Pearl, J; Woodward, WA | 1 |
Sorensen, A | 1 |
Gulmann, NC; Kaldan, B; Kobbernagal, F | 1 |
Iwamoto, ET; Loh, HH; Way, EL | 1 |
Gianutsos, G; Hynes, MD; Lal, H | 1 |
Ary, M; Lomax, P | 1 |
Brase, DA; Loh, HH; Tseng, LF | 1 |
Deacon, MA; Iorio, LC; Ryan, EA | 1 |
Asper, H; Bürki, HR; Ruch, W; Sayers, AC | 1 |
Kuschinsky, K | 1 |
Drawbaugh, RB; Gianutsos, G; Hynes, MD; Lal, H | 1 |
Moore, KE; Thornburg, JE | 1 |
Shishov, VI | 1 |
Baraban, JM; Bhat, RV; Cole, AJ; Worley, PF | 1 |
Gerlach, J; Lublin, H; Peacock, L | 1 |
Ellinwood, EH; Lee, TH; Zhang, H | 1 |
Bonuccelli, U; Corsini, GU; Muratorio, A; Piccini, P | 1 |
Carey, RJ | 1 |
Ahlenius, S; Ericson, EL; Högberg, K; Wijkström, A | 1 |
Cooper, T; DeCaria, CM; Hollander, E; Klein, DF; Nunes, E; Quitkin, FM; Wager, S | 1 |
Ackerman, JM; White, FJ | 1 |
Berggren, U | 1 |
Baldessarini, RJ; Campbell, A | 1 |
Alling, C; Balldin, J; Gottfries, CG; Långström, G; Lindstedt, G | 1 |
Childress, AR; McLellan, AT | 1 |
Anokhina, IP; Ivanets, NN; Nebarakova, TP; Reshchikova, EV | 1 |
Muscat, R; Towell, A; Willner, P | 1 |
Kantak, KM; Miczek, KA | 1 |
Dorce, VA; Palermo-Neto, J | 1 |
Czachura, JF; Gonzalez, LP | 1 |
Frussa-Filho, R; Palermo-Neto, J | 1 |
Martin, JR; Takemori, AE | 2 |
Davis, RE; Ellison, G; Sant, WW | 1 |
Bläsig, J; Herz, A; Papeschi, R | 2 |
Schneider, E; Ziegler, B | 1 |
Bläsig, J; Herz, A | 1 |
Lal, H; Puri, S | 1 |
Drawbaugh, RB; Gianutsos, G; Hynes, MD; Lal, H; Puri, SK | 1 |
Hedri, A | 1 |
Amitai, M; Dickhaut, HH; Hasenknopf, P | 1 |
Lorenzetti, OJ; Sancilio, LF | 1 |
Alhava, E; Mansner, R; Mattila, MJ | 1 |
6 review(s) available for apomorphine and Drug Withdrawal Symptoms
Article | Year |
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A Critical Review of Repurposing Apomorphine for Smoking Cessation.
Topics: Apomorphine; Dopamine Agonists; Drug Repositioning; Humans; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2015 |
Substance abuse and movement disorders.
Topics: Alcoholism; Animals; Apomorphine; Humans; Levodopa; Movement Disorders; Parkinson Disease; Substance Withdrawal Syndrome; Substance-Related Disorders | 2009 |
Rapid development of hypersensitivity and hyposensitivity to apomorphine and haloperidol: role of norepinephrine receptor mechanisms in CNS.
Topics: Animals; Apomorphine; Behavior, Animal; Brain; Dopamine; Haloperidol; Humans; Norepinephrine; Receptors, Adrenergic; Species Specificity; Substance Withdrawal Syndrome; Time Factors | 1980 |
Narcotic dependence, narcotic action and dopamine receptors.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Behavior, Animal; Brain; Corpus Striatum; Cyclic AMP; Dopamine; Drug Tolerance; Haloperidol; Humans; Mice; Narcotics; Prostaglandins E; Rats; Receptors, Drug; Substance Withdrawal Syndrome; Substance-Related Disorders; Synaptic Transmission | 1975 |
Aversive therapies for substance abuse: do they work?
Topics: Apomorphine; Aversive Therapy; Conditioning, Classical; Desensitization, Psychologic; Electroshock; Emetine; Extinction, Psychological; Humans; Naltrexone; Patient Compliance; Research Design; Substance Withdrawal Syndrome; Substance-Related Disorders; Succinylcholine | 1985 |
[Neurobiologic aspects of the morphine addictions].
Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dopamine; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Tolerance; Guinea Pigs; Humans; Mice; Models, Biological; Morphine; Morphine Dependence; Rats; Receptors, Drug; Serotonin; Substance Withdrawal Syndrome | 1974 |
3 trial(s) available for apomorphine and Drug Withdrawal Symptoms
Article | Year |
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Alcohol withdrawal and dopamine receptor sensitivity after prolonged abstinence.
Topics: Adult; Alcoholism; Apomorphine; Dopamine Agonists; Human Growth Hormone; Humans; Male; Receptors, Dopamine; Substance Withdrawal Syndrome; Temperance | 1996 |
Craving for alcohol and dopamine receptor sensitivity in alcohol-dependent men and control subjects.
Topics: Adult; Alcoholism; Apomorphine; Brain Chemistry; Conditioning, Psychological; Dopamine; Dopamine Agonists; Human Growth Hormone; Humans; Male; Middle Aged; Odorants; Receptors, Dopamine; Substance Withdrawal Syndrome | 2000 |
[Treatment of abstinence].
Topics: Alcoholism; Apomorphine; Barbital; Benzodiazepines; Clinical Trials as Topic; Humans; Substance Withdrawal Syndrome | 1976 |
112 other study(ies) available for apomorphine and Drug Withdrawal Symptoms
Article | Year |
---|---|
Loss of Awareness after Continuous Apomorphine Infusion Withdrawal in Parkinson's Disease.
Topics: Aged; Antiparkinson Agents; Apomorphine; Awareness; Humans; Infusions, Intravenous; Lethargy; Male; Parkinson Disease; Substance Withdrawal Syndrome | 2020 |
Acute lethargy after abrupt apomorphine withdrawal in Parkinson's disease.
Topics: Antiparkinson Agents; Apomorphine; Dopamine Agonists; Humans; Infusions, Subcutaneous; Intraoperative Neurophysiological Monitoring; Lethargy; Male; Middle Aged; Parkinson Disease; Substance Withdrawal Syndrome | 2019 |
Mesoaccumbens dopamine signaling alteration underlies behavioral transition from tolerance to sensitization to morphine rewarding properties during morphine withdrawal.
Topics: Action Potentials; Analgesics, Opioid; Animals; Apomorphine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopaminergic Neurons; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Signal Transduction; Substance Withdrawal Syndrome; Time Factors; Ventral Tegmental Area | 2014 |
Continuous perioperative apomorphine in deep brain stimulation surgery for Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Apomorphine; Deep Brain Stimulation; Female; Humans; Infusion Pumps; Male; Middle Aged; Nausea; Parkinson Disease; Perioperative Care; Retrospective Studies; Substance Withdrawal Syndrome | 2014 |
Long-term haloperidol treatment (but not risperidone) enhances addiction-related behaviors in mice: role of dopamine D2 receptors.
Topics: Amphetamine-Related Disorders; Animals; Antipsychotic Agents; Apomorphine; Corpus Striatum; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Female; Haloperidol; Limbic System; Long-Term Care; Mesencephalon; Mice; Motor Activity; Neural Pathways; Receptors, Dopamine D2; Risperidone; Stereotyped Behavior; Substance Withdrawal Syndrome; Substantia Nigra; Up-Regulation | 2009 |
Dopamine agonist withdrawal syndrome: the apomorphine solution.
Topics: Apomorphine; Dopamine Agonists; Humans; Substance Withdrawal Syndrome | 2010 |
Increased dopamine receptor activity in the nucleus accumbens shell ameliorates anxiety during drug withdrawal.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anxiety; Apomorphine; Benzazepines; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Male; Morphine; Nucleus Accumbens; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reflex, Startle; Substance Withdrawal Syndrome | 2012 |
Monosialoganglioside (GM1) attenuates the behavioural effects of long-term haloperidol administration in supersensitive rats.
Topics: Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; G(M1) Ganglioside; Haloperidol; Immobilization; Locomotion; Male; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 2004 |
Neuroendocrinological and neuropsychological correlates of dopaminergic function in nicotine dependence.
Topics: Adult; Apomorphine; Dopamine D2 Receptor Antagonists; Human Growth Hormone; Humans; Male; Motivation; Neuropsychological Tests; Nicotine; Receptors, Dopamine D2; Smoking; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2004 |
The partial D2-like dopamine receptor agonist terguride acts as a functional antagonist in states of high and low dopaminergic tone: evidence from preweanling rats.
Topics: Animals; Animals, Newborn; Apomorphine; Body Weight; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Hyperkinesis; Lisuride; Methyltyrosines; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase | 2005 |
Cerebral dopamine function in rats following withdrawal from one year of continuous neuroleptic administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Binding Sites; Body Weight; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Male; Motor Activity; Mouth; Movement; Rats; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine; Time Factors; Trifluoperazine | 1980 |
Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain; Chlorpromazine; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Mouth Diseases; Movement Disorders; Occipital Lobe; Rats; Substance Withdrawal Syndrome | 1980 |
Receptor-mediated dopaminergic function after ethanol withdrawal.
Topics: Alcoholism; Animals; Apomorphine; Brain; Dihydroxyphenylalanine; Dopamine; Haloperidol; Humans; Male; Mice; Mice, Inbred C57BL; Receptors, Dopamine; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase | 1980 |
Behavioural and biochemical alterations following haloperidol treatment and withdrawal: the animal model of tardive dyskinesia reexamined.
Topics: Animals; Apomorphine; Behavior, Animal; Brain; Disease Models, Animal; Dopamine; Glutamate Decarboxylase; Haloperidol; Humans; Male; Motor Activity; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase | 1983 |
Neuroendocrine effects of apomorphine in chronic schizophrenic patients under long-term neuroleptic therapy and after drug withdrawal: relations to psychopathology and tardive dyskinesia.
Topics: Adult; Aged; Antipsychotic Agents; Apomorphine; Chronic Disease; Dyskinesia, Drug-Induced; Female; Growth Hormone; Humans; Male; Prolactin; Schizophrenia; Schizophrenic Psychology; Substance Withdrawal Syndrome; Time Factors | 1984 |
Effects of ethanol administration and withdrawal on neurotransmitter receptor systems in C57 mice.
Topics: Alcoholism; Animals; Apomorphine; Behavior, Animal; Body Temperature; Humans; Male; Mice; Mice, Inbred C57BL; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Neurotransmitter; Substance Withdrawal Syndrome | 1980 |
Hypophysectomy fails to affect the supersensitivity of striatal dopamine target cells induced by prolonged haloperidol treatment.
Topics: Acetylcholine; Animals; Apomorphine; Body Weight; Brain Chemistry; Corpus Striatum; Dopamine; Ergolines; Haloperidol; Humans; Hypophysectomy; Male; Pergolide; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1984 |
Effects of apomorphine administration on rearing activity of control and experimental rats withdrawn from long-term haloperidol treatment.
Topics: Animals; Apomorphine; Haloperidol; Humans; Male; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substance Withdrawal Syndrome | 1984 |
Effects of apomorphine administration on locomotor activity of control and experimental rats withdrawn from long-term haloperidol treatment.
Topics: Animals; Apomorphine; Haloperidol; Humans; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substance Withdrawal Syndrome; Time Factors | 1983 |
Spontaneous activity and apomorphine stereotypy during and after withdrawal from 3 1/2 months continuous administration of haloperidol: some methodological issues.
Topics: Animals; Apomorphine; Body Weight; Haloperidol; Humans; Male; Motor Activity; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1980 |
Chronic L-DOPA treatment of mice: a behavioural and biochemical study.
Topics: Animals; Apomorphine; Benserazide; Body Temperature Regulation; Brain; Clonidine; Dihydroxyphenylalanine; Dopamine; Humans; Levodopa; Male; Mice; Motor Activity; Norepinephrine; Substance Withdrawal Syndrome | 1981 |
[Therapy of addicted patients].
Topics: Apomorphine; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders | 1982 |
Influence of lisuride on morphine withdrawal signs in the rat: a dopamine-mimetic effect.
Topics: Aggression; Animals; Apomorphine; Dopamine; Ergolines; Haloperidol; Humans; Lisuride; Male; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Sulpiride | 1982 |
Differential enhancement of behavioral sensitivity to apomorphine following chronic treatment of rats with (-)-sulpiride and haloperidol.
Topics: Animals; Apomorphine; Behavior, Animal; Exploratory Behavior; Haloperidol; Humans; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Sulpiride | 1982 |
Differential liabilities of haloperidol and thioridazine for inducing apomorphine hypersensitivity.
Topics: Animals; Apomorphine; Benztropine; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Humans; Limbic System; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine | 1982 |
Treatment of alcohol withdrawal symptoms.
Topics: Alcoholism; Apomorphine; Humans; Substance Withdrawal Syndrome | 1982 |
Estrogen in experimental tardive dyskinesia.
Topics: Animals; Apomorphine; Castration; Dyskinesia, Drug-Induced; Estradiol; Female; Haloperidol; Humans; Rats; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome | 1980 |
Tolerance to fluphenazine and supersensitivity to apomorphine in central dopaminergic systems after chronic fluphenazine decanoate treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Fluphenazine; Haloperidol; Homovanillic Acid; Humans; Male; Olfactory Bulb; Rats; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1980 |
Changes in cerebral dopamine function induced by a year's administration of trifluoperazine or thioridazine and their subsequent withdrawal.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Brain; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Humans; Male; Rats; Spiperone; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine; Time Factors; Trifluoperazine | 1980 |
Antagonism of dopamine supersensitivity by estrogen: neurochemical studies in an animal model of tardive dyskinesia.
Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Estradiol; Female; Haloperidol; Humans; Rats; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome | 1981 |
[Effect of psychotropic drugs on sleep disorders in rats during alcohol withdrawal].
Topics: Alcoholism; Animals; Anti-Anxiety Agents; Apomorphine; Benzodiazepines; Benzodiazepinones; Haloperidol; Humans; Male; Psychotropic Drugs; Rats; Sleep Wake Disorders; Sodium Oxybate; Substance Withdrawal Syndrome | 1981 |
Subsensitivity of the presynaptic dopamine receptors in cat heart after the termination of chronic haloperidol treatment.
Topics: Animals; Apomorphine; Blood Pressure; Cats; Female; Haloperidol; Heart; Humans; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Receptors, Dopamine; Substance Withdrawal Syndrome; Tyramine | 1981 |
[New approach to treating chronic alcoholism].
Topics: Alcohol Withdrawal Delirium; Alcoholism; Apomorphine; Dopamine; Dopamine Antagonists; Drug Evaluation; Humans; Male; Substance Withdrawal Syndrome | 1980 |
Ethanol withdrawal does not induce a reduction in the number of spontaneously active dopaminergic neurons in the mesolimbic system.
Topics: Anesthesia; Animals; Apomorphine; Chloral Hydrate; Dopamine; Dopamine Agonists; Ethanol; Limbic System; Male; Neurons; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Ventral Tegmental Area | 1995 |
Dopaminergic responsivity in alcoholism: trait, state, or residual marker?
Topics: Adult; Alcohol Drinking; Alcoholism; Apomorphine; Biomarkers; Ethanol; Female; Growth Hormone; Humans; Longitudinal Studies; Male; Middle Aged; Severity of Illness Index; Substance Withdrawal Syndrome | 1995 |
Differential involvement of voltage-dependent calcium channels in apomorphine-induced hypermotility and stereotypy.
Topics: Animals; Apomorphine; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Electroshock; Male; Morphine; Motor Activity; Nifedipine; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome; Up-Regulation | 1994 |
Subchronic treatment with haloperidol and clozapine in rats with neonatal excitotoxic hippocampal damage.
Topics: Animals; Animals, Newborn; Apomorphine; Clozapine; Female; Haloperidol; Hippocampus; Ibotenic Acid; Motor Activity; Neurotoxins; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome | 1994 |
Time-dependent changes in sensitivity to apomorphine and monoamine receptors following withdrawal from continuous cocaine administration in rats.
Topics: Animals; Apomorphine; Autoradiography; Behavior, Animal; Brain; Cocaine; Male; Motor Activity; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1994 |
Withdrawal from continuous or intermittent cocaine administration: changes in D2 receptor function.
Topics: Animals; Apomorphine; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger; Substance Withdrawal Syndrome | 1994 |
The effects of acute levodopa withdrawal on motor performance and dopaminergic receptor sensitivity in patients with Parkinson's disease.
Topics: Aged; Apomorphine; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Psychomotor Performance; Receptors, Dopamine; Substance Withdrawal Syndrome | 1993 |
Apomorphine SC treatment in parkinsonian patients with long-term L-dopa syndrome during L-dopa drug holiday.
Topics: Adult; Aged; Antiparkinson Agents; Apomorphine; Dihydroxyphenylalanine; Dopamine Agents; Drug Administration Schedule; Humans; Infusions, Parenteral; Middle Aged; Risk Factors; Skin; Substance Withdrawal Syndrome | 1995 |
Differences between haloperidol- and pimozide-induced withdrawal syndrome: a role for Ca2+ channels.
Topics: Animals; Antipsychotic Agents; Apomorphine; Calcium Channels; Haloperidol; Male; Motor Activity; Nifedipine; Nitrendipine; Pimozide; Rats; Rats, Wistar; Receptors, Dopamine D1; Substance Withdrawal Syndrome | 1995 |
Differential effects of SCH 23390 on the apomorphine subsensitivity in the substantia nigra and ventral tegmental area 1 day following withdrawal from continuous or intermittent cocaine pretreatment.
Topics: Animals; Apomorphine; Benzazepines; Cocaine; Male; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substantia Nigra; Tegmentum Mesencephali | 1997 |
Differential influence of D1 and D2 dopamine receptors on acute opiate withdrawal in guinea-pig isolated ileum.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Apomorphine; Dopamine Agents; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Haloperidol; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Pyrrolidines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 1997 |
Behavioural subsensitivity induced by long-term administration of a low dose of haloperidol to rats.
Topics: Administration, Oral; Animals; Apomorphine; Autoreceptors; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Haloperidol; Injections, Intraperitoneal; Locomotion; Male; Random Allocation; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome | 1997 |
Responses to propofol in relation to GABA functionality of discrete parts of the brain of rats.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Apomorphine; Behavior, Animal; Blood Pressure; Brain; Female; gamma-Aminobutyric Acid; Heart Rate; Propofol; Rats; Rats, Wistar; Reflex; Substance Withdrawal Syndrome; Synaptic Transmission | 1997 |
Influence of the dopamine D2 receptor (DRD2) genotype on neuroadaptive effects of alcohol and the clinical outcome of alcoholism.
Topics: Adaptation, Physiological; Adult; Aged; Alcoholism; Apomorphine; Female; Follow-Up Studies; Genotype; Human Growth Hormone; Humans; Male; Middle Aged; Polymerase Chain Reaction; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Suicide, Attempted | 1997 |
The role of dopamine in the expression of morphine withdrawal.
Topics: Adrenergic Agents; Analgesia; Analgesics, Opioid; Analysis of Variance; Animals; Apomorphine; Dopamine; Dopamine Agents; Dopamine Antagonists; Hypothermia; Levodopa; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Oxidopamine; Substance Withdrawal Syndrome | 1998 |
Monosialoganglioside increased the in vivo affinity of D2 receptors for apomorphine in supersensitive rats.
Topics: Animals; Antipsychotic Agents; Apomorphine; Corpus Striatum; G(M1) Ganglioside; Haloperidol; Kinetics; Metoclopramide; Rats; Receptors, Dopamine D2; Stereotyped Behavior; Substance Withdrawal Syndrome | 1998 |
Altered activity of midbrain dopamine neurons following 7-day withdrawal from chronic cocaine abuse is normalized by D2 receptor stimulation during the early withdrawal phase.
Topics: Animals; Apomorphine; Benzazepines; Cocaine-Related Disorders; Dopamine; Dopamine Agonists; Dopamine Antagonists; Electrophysiology; Male; Mesencephalon; Neurons; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Substantia Nigra; Ventral Tegmental Area | 1999 |
Modification of naloxone-induced withdrawal signs by dextromethorphan in morphine-dependent mice.
Topics: Animals; Apomorphine; Behavior, Animal; Benzazepines; Dextromethorphan; Domperidone; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Grooming; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Pain; Substance Withdrawal Syndrome; Sulpiride | 1999 |
Behavioral activation induced by D(2)-like receptor stimulation during opiate withdrawal.
Topics: Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Locomotion; Male; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereotyped Behavior; Substance Withdrawal Syndrome | 2000 |
Expression of fos-related antigens in the nucleus accumbens during opiate withdrawal and their attenuation by a D2 dopamine receptor agonist.
Topics: Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Immunohistochemistry; Lithium Chloride; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Substance Withdrawal Syndrome | 2000 |
Genetic analysis of the mu-opioid receptor in alcohol-dependent individuals.
Topics: Adult; Alcoholism; Alleles; Apomorphine; Dopamine Agonists; Exploratory Behavior; Female; Gene Frequency; Human Growth Hormone; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 2001 |
Effect of apomorphine on the antinociceptive activity of morphine.
Topics: Analgesics, Opioid; Animals; Apomorphine; Drug Synergism; Drug Tolerance; Female; Humans; Male; Mice; Morphine; Nalorphine; Rats; Rats, Inbred Strains; Reaction Time; Substance Withdrawal Syndrome; Time Factors | 1977 |
Behavioural correlates of modified dopaminergic/anticholinergic responses following chronic treatment with neuroleptic agents of differing activity spectra.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Body Weight; Dexetimide; Dopamine; Exploratory Behavior; Humans; Male; Motor Activity; Parasympatholytics; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1978 |
[Comparisons between the effects of apomorphine and naloxone in acutely dependent morphinized rats and mice (author's transl)].
Topics: Animals; Antipsychotic Agents; Apomorphine; Humans; Male; Methyltyrosines; Mice; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome; Time Factors | 1978 |
The effect of chronic administration and withdrawal of amphetamine on cerebral dopamine receptor sensitivity.
Topics: Animals; Apomorphine; Behavior, Animal; Biogenic Amines; Brain; Brain Chemistry; Dextroamphetamine; Drug Interactions; Humans; Male; Mice; Mice, Inbred Strains; Receptors, Dopamine; Substance Withdrawal Syndrome; Time Factors | 1978 |
Prostaglandins, cyclic AMP and the mechanism of opiate dependence.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Brain; Cattle; Codeine; Cyclic AMP; Humans; In Vitro Techniques; Male; Morphine; Morphine Dependence; Naloxone; Prostaglandins; Rats; Seminal Vesicles; Substance Withdrawal Syndrome; Substance-Related Disorders; Tissue Extracts | 1975 |
Cyclic GMP and GABA levels in rat striatum and cerebellum during morphine withdrawal: effect of apomorphine.
Topics: Aminobutyrates; Animals; Apomorphine; Brain Chemistry; Cerebellum; Corpus Striatum; Cyclic GMP; gamma-Aminobutyric Acid; Humans; Male; Morphine Dependence; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1977 |
Site of naloxone-precipitated opiate withdrawal dissociates from that at which apomorphine reinitiates this phenomenon.
Topics: Animals; Apomorphine; Clonidine; Humans; Injections, Intraventricular; Male; Naloxone; Rats; Receptors, Opioid; Substance Withdrawal Syndrome | 1978 |
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Dexetimide; Dextromoramide; Dogs; Dopamine; Drug Combinations; Haloperidol; Humans; Meperidine; Methadone; Mice; Morphine; Phenoperidine; Pimozide; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome; Tranquilizing Agents; Vomiting | 1975 |
Interactions of thyrotropin releasing hormone and morphine sulfate in rodents.
Topics: Analgesics; Animals; Apomorphine; Behavior, Animal; Body Weight; Chlorpromazine; Dronabinol; Humans; Mice; Morphinans; Morphine; Pain; Pentobarbital; Rats; Substance Withdrawal Syndrome; Thyrotropin-Releasing Hormone | 1977 |
Effects of withdrawal from chronic amphetamine intoxication on exploratory and stereotyped behaviors in the rat.
Topics: Animals; Apomorphine; Behavior; Dextroamphetamine; Exploratory Behavior; Humans; Male; Methyltyrosines; Rats; Reserpine; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1977 |
Enhanced prolactin inhibition following chronic treatment with haloperidol and morphine.
Topics: Animals; Apomorphine; Dopamine; Haloperidol; Humans; Hypothalamus; Male; Morphine; Neural Pathways; Prolactin; Rats; Substance Withdrawal Syndrome; Thalamus | 1977 |
Dopaminergic mechanisms in precipitated withdrawal in morphine-dependent rats.
Topics: Animals; Apomorphine; Body Temperature; Dopamine; Drug Interactions; Humans; Male; Morphine Dependence; Naloxone; Pimozide; Rats; Substance Withdrawal Syndrome; Time Factors | 1977 |
Influence of morphine dependence and withdrawal on circling behaviour in rats with unilateral nigral lesions [proceedings].
Topics: Animals; Apomorphine; Behavior, Animal; Humans; Male; Morphine; Morphine Dependence; Rats; Rotation; Substance Withdrawal Syndrome; Substantia Nigra | 1977 |
Changes in sensitivity to operant effects of dopaminergic and cholinergic agents following morphine withdrawal in rats.
Topics: Animals; Apomorphine; Conditioning, Operant; Dopamine; Female; Haloperidol; Humans; Morphine; Pilocarpine; Rats; Reinforcement Schedule; Scopolamine; Substance Withdrawal Syndrome; Time Factors | 1977 |
Effect of chronic chlorpromazine administration or prior treatment with reserpine on brain apomorphine concentrations and apomorphine-induced sterotyped behaviour in the rat.
Topics: Animals; Apomorphine; Behavior; Brain Chemistry; Chlorpromazine; Drug Interactions; Humans; Male; Motor Activity; Rats; Reserpine; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1977 |
Effect of apomorphine and its N-propyl homologue on ethanol withdrawal head twitches in mice.
Topics: Alcoholism; Animals; Apomorphine; Humans; Male; Mice; Substance Withdrawal Syndrome | 1977 |
Changes in sensitivity to apomorphine during morphine dependence and withdrawal in rats.
Topics: Animals; Apomorphine; Dopamine; Humans; Male; Morphine Dependence; Naloxone; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1976 |
[Apomorphine treatment of withdrawal symptoms in young opiate addicts].
Topics: Adolescent; Adult; Apomorphine; Hospitalization; Humans; Injections, Subcutaneous; Morphine Dependence; Opium; Substance Withdrawal Syndrome | 1976 |
Dopaminergic-cholinergic interactions in naloxone-induced circling in morphine-dependent rats with nigral lesions.
Topics: Animals; Apomorphine; Arecoline; Atropine; Behavior; Dopamine; Humans; Hydroxydopamines; Male; Morphine Dependence; Naloxone; Parasympathetic Nervous System; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Substantia Nigra | 1976 |
Enhancement of morphine-withdrawal and apomorphine-induced aggression by clonidine.
Topics: Aggression; Animals; Apomorphine; Clonidine; Humans; Male; Morphine; Rats; Stimulation, Chemical; Substance Withdrawal Syndrome; Vocalization, Animal | 1976 |
Dopaminergic sites involved in morphine withdrawal hypothermia.
Topics: Animals; Apomorphine; Body Temperature; Dopamine; Drug Implants; Humans; Hypothalamus; Injections; Male; Morphine; Naloxone; Pimozide; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome | 1976 |
Dopaminergic influence on withdrawal jumping behavior in morphine-dependent mice.
Topics: Animals; Apomorphine; Brain; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Methyltyrosines; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Morphine Dependence; Motor Activity; Naloxone; Species Specificity; Substance Withdrawal Syndrome | 1976 |
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Injections, Intraperitoneal; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotics; Pentazocine; Substance Withdrawal Syndrome | 1975 |
Dopaminergic mechanisms in withdrawal hypothermia in morphine dependent rats.
Topics: Animals; Apomorphine; Dopamine; Humans; Hypothermia; Male; Morphine; Naloxone; Pimozide; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1975 |
Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine.
Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzazepines; Dibenzoxazepines; Disease Models, Animal; Dopamine; Drug Tolerance; Female; Haloperidol; Homovanillic Acid; Humans; Loxapine; Male; Movement Disorders; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome | 1975 |
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome | 1975 |
Paradoxical absence of aggression during naloxone-precipitated morphine withdrawal.
Topics: Aggression; Animals; Apomorphine; Dextroamphetamine; Humans; Male; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome | 1975 |
Supersensitivity to dopaminergic agonists induced by haloperidol.
Topics: Animals; Apomorphine; Diet; Dopamine; Drug Interactions; Haloperidol; Humans; Male; Mice; Motor Activity; Pimozide; Receptors, Drug; Substance Withdrawal Syndrome | 1975 |
[Electrolyte metabolism in alcoholic patients during therapy and prolonged abstinence].
Topics: Adrenal Cortex; Adrenal Insufficiency; Adult; Alcoholism; Apomorphine; Disulfiram; Erythrocytes; Humans; Middle Aged; Mineralocorticoids; Potassium; Sodium; Substance Withdrawal Syndrome | 1976 |
Activation of the zinc finger encoding gene krox-20 in adult rat brain: comparison with zif268.
Topics: Animals; Apomorphine; Benzazepines; Brain; DNA-Binding Proteins; Early Growth Response Protein 1; Early Growth Response Protein 2; Electroshock; Haloperidol; Immediate-Early Proteins; Male; Morphine; Naltrexone; Nucleic Acid Hybridization; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Seizures; Substance Withdrawal Syndrome; Transcription Factors; Transcription, Genetic; Zinc Fingers | 1992 |
Effect of D1 and D2 agonists in primates withdrawn from long-term treatment with haloperidol: the potential role of dopamine D1 receptors in dyskinesia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Cebus; Dopamine Agents; Dyskinesia, Drug-Induced; Ergolines; Female; Grooming; Haloperidol; Hypnotics and Sedatives; Male; Motor Activity; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Substance Withdrawal Syndrome | 1992 |
The progressive changes of neuronal activities of the nigral dopaminergic neurons upon withdrawal from continuous infusion of cocaine.
Topics: Animals; Apomorphine; Cocaine; Dopamine; Male; Neurons; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substantia Nigra | 1992 |
Apomorphine in malignant syndrome due to levodopa withdrawal.
Topics: Aged; Apomorphine; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome | 1992 |
Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Carbidopa; Corpus Striatum; Denervation; Drug Tolerance; Functional Laterality; Homovanillic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1991 |
Behavioural and biochemical effects of subchronic treatment with raclopride in the rat: tolerance and brain monoamine receptor sensitivity.
Topics: Animals; Apomorphine; Brain; Dihydroxyphenylalanine; Dopamine Antagonists; Drug Tolerance; Male; Motor Activity; Raclopride; Rats; Rats, Inbred Strains; Reserpine; Salicylamides; Substance Withdrawal Syndrome; Time Factors | 1991 |
Dopaminergic sensitivity and cocaine abuse: response to apomorphine.
Topics: Adult; Anxiety; Apomorphine; Attention; Brain; Cocaine; Dopamine; Homovanillic Acid; Humans; Male; Prolactin; Receptors, Dopamine; Substance Withdrawal Syndrome; Substance-Related Disorders | 1990 |
A10 somatodendritic dopamine autoreceptor sensitivity following withdrawal from repeated cocaine treatment.
Topics: Animals; Apomorphine; Brain; Cocaine; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Salicylamides; Substance Withdrawal Syndrome; Substance-Related Disorders | 1990 |
The effect of chronic lithium administration and withdrawal on locomotor activity and apomorphine-induced locomotor stimulation in rats.
Topics: Animals; Apomorphine; Chlorides; Exploratory Behavior; Lithium; Lithium Chloride; Male; Motor Activity; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Time Factors | 1988 |
Prolonged pharmacologic activity of neuroleptics.
Topics: Animals; Antipsychotic Agents; Apomorphine; Dose-Response Relationship, Drug; Half-Life; Haloperidol; Humans; Kinetics; Rats; Risk; Stereotyped Behavior; Substance Withdrawal Syndrome | 1985 |
Changes in dopamine receptor sensitivity in humans after heavy alcohol intake.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anticonvulsants; Apomorphine; Benzodiazepines; Chlormethiazole; Ethanol; Female; Growth Hormone; Humans; Male; Middle Aged; Pituitary Gland, Anterior; Receptors, Dopamine; Substance Withdrawal Syndrome | 1985 |
[Dopamine receptor stimulants in the treatment of alcoholism].
Topics: Alcoholism; Apomorphine; Bromocriptine; Dopamine; Dopamine Agents; Drug Evaluation; Ethanol; Humans; Male; Substance Withdrawal Syndrome | 1988 |
Dopamine autoreceptors in the ventral tegmental area show subsensitivity following withdrawal from chronic antidepressant drug treatment.
Topics: Animals; Antidepressive Agents; Apomorphine; Desipramine; Feeding Behavior; Male; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome; Tegmentum Mesencephali | 1986 |
Social, motor, and autonomic signs of morphine withdrawal: differential sensitivities to catecholaminergic drugs in mice.
Topics: Animals; Apomorphine; Autonomic Nervous System; Catecholamines; Clonidine; Cocaine; Dextroamphetamine; Levodopa; Mice; Mice, Inbred Strains; Morphine Dependence; Psychomotor Performance; Reaction Time; Social Behavior; Substance Withdrawal Syndrome | 1988 |
Effects of ovariectomy and of estrogen administration on some dopamine-related behaviors in the rat.
Topics: Analysis of Variance; Animals; Apomorphine; Estradiol; Female; Haloperidol; Ovariectomy; Random Allocation; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substance Withdrawal Syndrome; Task Performance and Analysis | 1988 |
Ethanol withdrawal alters apomorphine-induced motility.
Topics: Animals; Apomorphine; Ethanol; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome | 1988 |
Effects of single and long-term metoclopramide administration on open field and stereotyped behavior of rats.
Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Male; Metoclopramide; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substance Withdrawal Syndrome | 1988 |
Modification of the development of acute opiate tolerance by increased dopamine receptor sensitivity.
Topics: Animals; Apomorphine; Behavior, Animal; Drug Interactions; Drug Tolerance; Levorphanol; Lithium; Male; Mice; Morphine; Naloxone; Narcotics; Opioid-Related Disorders; Receptors, Dopamine; Spiperone; Substance Withdrawal Syndrome | 1987 |
Chronically administered morphine increases dopamine receptor sensitivity in mice.
Topics: Analgesia; Animals; Apomorphine; Behavior, Animal; Binding Sites; Brain; Drug Implants; Drug Tolerance; Hypothermia; Lithium; Male; Mice; Morphine; Naloxone; Receptors, Dopamine; Spiperone; Substance Withdrawal Syndrome | 1986 |
Continuous low-level apomorphine administration induces motor abnormalities and hallucinogen-like behaviors.
Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Dopamine; Drug Implants; Hallucinogens; Humans; Injections, Subcutaneous; Male; Motor Activity; Rats; Rats, Inbred Strains; Serotonin; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1985 |
[Significance of catecholamines for the manifestation of morphine withdrawal in the rat].
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Catecholamines; Desipramine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Humans; Levallorphan; Methyltyrosines; Morphine; Morphine Dependence; Motor Activity; Norepinephrine; Rats; Substance Withdrawal Syndrome | 1974 |
Role of catecholaminergic mechanisms in the expression of the morphine abstinence syndrome in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benserazide; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Eye Movements; Humans; Levallorphan; Male; Methyltyrosines; Morphine; Morphine Dependence; Motor Activity; Nasal Mucosa; Norepinephrine; Piperazines; Rats; Serotonin; Substance Withdrawal Syndrome | 1974 |
[Treatment of withdrawal syndrome with apomorphine].
Topics: Administration, Oral; Adolescent; Adult; Apomorphine; Humans; Injections, Subcutaneous; Male; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders | 1974 |
Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression.
Topics: Aggression; Amphetamine; Animals; Apomorphine; Dihydroxyphenylalanine; Haloperidol; Humans; Male; Methadone; Methyltyrosines; Morphine Dependence; Premedication; Rats; Substance Withdrawal Syndrome | 1973 |
Effect of apomorphine and nigrostriatal lesions on aggression and striatal dopamine turnover during morphine withdrawal: evidence for dopaminergic supersensitivity in protracted abstinence.
Topics: Aggression; Animals; Apomorphine; Corpus Striatum; Dopamine; Humans; Male; Morphine; Rats; Substance Withdrawal Syndrome; Substantia Nigra; Time Factors | 1974 |
[Apomorphine in opiate withdrawal treatment].
Topics: Adult; Apomorphine; Humans; Male; Morphine Dependence; Substance Withdrawal Syndrome | 1972 |
[Therapy of withdrawal symptoms in "fixers". (Drug abuse of adolescents by intravenous injection)].
Topics: Adolescent; Adult; Anxiety; Apomorphine; Female; Hallucinations; Humans; Male; Morphine Dependence; Psychotherapy; Substance Withdrawal Syndrome | 1972 |
Morphine dependent rats as a model for evaluating potential addiction liability of analgesic compounds.
Topics: Analgesics; Animals; Apomorphine; Azepines; Behavior, Animal; Codeine; Dextropropoxyphene; Diphenhydramine; Histamine; Humans; Meperidine; Meprobamate; Methadone; Methods; Morphine Dependence; Pentazocine; Pyrrolidines; Rats; Salicylates; Serotonin; Substance Withdrawal Syndrome | 1970 |
Modification by disulfiram or methyltyrosine methylester (H 44-68) of abstinence symptoms in morphine-tolerant rats.
Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Depression, Chemical; Disulfiram; Dopamine; Drug Synergism; Drug Tolerance; Esters; Female; Humans; Male; Methyltyrosines; Morphine; Myocardium; Nalorphine; Norepinephrine; Rats; Stimulation, Chemical; Substance Withdrawal Syndrome | 1968 |