Page last updated: 2024-08-17

apomorphine and Drug Withdrawal Symptoms

apomorphine has been researched along with Drug Withdrawal Symptoms in 121 studies

Research

Studies (121)

TimeframeStudies, this research(%)All Research%
pre-199078 (64.46)18.7374
1990's27 (22.31)18.2507
2000's9 (7.44)29.6817
2010's6 (4.96)24.3611
2020's1 (0.83)2.80

Authors

AuthorsStudies
Mendes, A; Oliveira, V; Videira, G1
Castrioto, A; Cavallieri, F; Fraix, V; Krack, P; Meoni, S; Moro, E1
Cui, C; Hu, L; Li, Y; Sun, L1
Kinfe, TM; Slotty, PJ; Vesper, J; Wille, C1
Cousin, MA; Ebbert, JO; Klee, EW; Morales-Rosado, JA1
Callegaro-Filho, D; Carvalho, RC; Frussa-Filho, R; Fukushiro, DF; Helfer, DC; Sanday, L; Silva, RH; Trombin, TF; Zanlorenci, LH1
San Luciano, M; Saunders-Pullman, R1
Erikh, I; Schlesinger, I; Zaaroor, M1
Gewirtz, JC; Radke, AK1
Frussa-Filho, R; Palermo-Neto, J; Perry, JC; Tufik, S; Vital, MA1
Budde, H; Karow, AC; Schmidt, LG; Smolka, MN1
Farley, CM; Hernandez, RM; McDougall, SA; Reichel, CM1
Clow, A; Jenner, P; Marsden, CD; Theodorou, A2
Glassman, HN; Glassman, RB1
Black, RF; Hoffman, PL; Tabakoff, B1
Lapierre, YD; Rastogi, RB; Rastogi, SK; Singhal, RL1
Ackenheil, M; Albus, M; May, G; Müller-Spahn, F; Naber, D; Welter, D; Zander, K1
Dibner, MD; Melchior, C; Molinoff, PB; Rabin, RA; Wolfe, BB; Zahniser, NR1
Fage, D; Scatton, B1
Bernardi, MM; Palermo-Neto, J2
Gamble, SJ; Waddington, JL1
Bailey, R; Crisp, E; Jackson, DM; Jenkins, O1
Schmidt, L1
Baggio, G; Ferrari, F1
Dall'Olio, R; Gandolfi, O; Montanaro, N; Vaccheri, A1
Carey, RJ; De Veaugh-Geiss, J; Devanand, DP1
Cools, AR1
Mayne, DG1
Borison, RL; Diamond, BI; Gordon, JH1
Roth, RH; Wheeler, SC1
Diamond, BI; Gordon, JH1
Burov, IuV; Viglinskaia, IV1
Arnerić, SP; Flynn, JR; Long, JP; Verimer, T; Walsh, BJ1
Anokhina, IP; Ivanets, NN; Morozov, GV1
Diana, M; Gessa, GL; Muntoni, AL; Pistis, M1
Dettling, M; Dufeu, P; Gräf, KJ; Heinz, A; Rommelspacher, H; Schmidt, LG1
Antkiewicz-Michaluk, L; Michaluk, J; Romańska, I; Vetulani, J1
Lipska, BK; Weinberger, DR1
Lucki, I; McGonigle, P; Neisewander, JL1
Caron, MG; Ellinwood, EH; Joyner, CM; King, GR; Lee, TH; Silvia, C; Xue, Z1
Fernandez, W; Lees, AJ; Turjanski, N1
Bergamasco, B; Delsedime, M; Ferrero, B; Giangrandi, C; Priano, L; Rizzone, M; Scarzella, L1
Antkiewicz-Michaluk, L; Karolewicz, B; Michaluk, J; Vetulani, J1
Boening, J; Davids, E; Jakob, F; Thome, J; Weijers, G; Wiesbeck, GA; Wodarz, N1
Ellinwood, EH; Gao, WY; Lee, TH1
Capasso, A; Sorrentino, L1
Abílio, VC; Bergamo, M; Frussa-Filho, R; Palermo-Neto, J1
Cools, AR; Dirksen, R; Ellenbroek, B; van Egmond, J1
Dettling, M; Dufeu, P; Finckh, U; Giraldo-Velasquez, M; Gräf, KJ; Harms, H; Heinz, A; Kuhn, S; Otto, G; Pelz, J; Rolfs, A; Rommelspacher, H; Sander, T; Schmidt, LG1
el-Kadi, AO; Sharif, SI1
Frussa-Filho, R; Palermo-Neto, J; Vital, MB1
Davidson, C; Ellinwood, EH; Gao, WY; Lee, TH1
Farzin, D1
Aston-Jones, G; Druhan, JP; Walters, CL2
Gross, JP; Wiesbeck, GA1
Hoehe, MR; Rommelspacher, H; Samochowiec, J; Schmidt, LG; Smolka, M1
Dunai-Kovács, Z; Székely, JI1
Costall, B; Naylor, RJ; Owen, RT1
Jacob, JJ; Tremblay, EC1
Jenner, P; Marsden, CD; Pycock, C1
Collier, HO; Francis, DL; McDonald-Gibson, WJ; Roy, AC; Saeed, SA1
Lal, H1
Choma, P; Puri, SK; Volicer, L1
Bläsig, J; Herz, A; Laschka, E; Schulz, R1
Gianutsos, G; Lal, H; Puri, SK1
Chau-Pham, T; Dewey, WL; Martin, BR; Prnage, AJ1
Hitzemann, BA; Hitzemann, RJ; Loh, HH; Sampath-Khanna, S; Tseng, LF1
Brown, G; Brown, W; Drawbaugh, R; Hynes, M; Lal, H1
Ary, M; Cox, B; Lomax, P3
Halliwell, JV; Kumar, R1
Cox, RD; Glick, SD1
Lal, S; Sourkes, TL; Symes, AL; Tsang, D; Young, SN1
Pearl, J; Woodward, WA1
Sorensen, A1
Gulmann, NC; Kaldan, B; Kobbernagal, F1
Iwamoto, ET; Loh, HH; Way, EL1
Gianutsos, G; Hynes, MD; Lal, H1
Ary, M; Lomax, P1
Brase, DA; Loh, HH; Tseng, LF1
Deacon, MA; Iorio, LC; Ryan, EA1
Asper, H; Bürki, HR; Ruch, W; Sayers, AC1
Kuschinsky, K1
Drawbaugh, RB; Gianutsos, G; Hynes, MD; Lal, H1
Moore, KE; Thornburg, JE1
Shishov, VI1
Baraban, JM; Bhat, RV; Cole, AJ; Worley, PF1
Gerlach, J; Lublin, H; Peacock, L1
Ellinwood, EH; Lee, TH; Zhang, H1
Bonuccelli, U; Corsini, GU; Muratorio, A; Piccini, P1
Carey, RJ1
Ahlenius, S; Ericson, EL; Högberg, K; Wijkström, A1
Cooper, T; DeCaria, CM; Hollander, E; Klein, DF; Nunes, E; Quitkin, FM; Wager, S1
Ackerman, JM; White, FJ1
Berggren, U1
Baldessarini, RJ; Campbell, A1
Alling, C; Balldin, J; Gottfries, CG; Långström, G; Lindstedt, G1
Childress, AR; McLellan, AT1
Anokhina, IP; Ivanets, NN; Nebarakova, TP; Reshchikova, EV1
Muscat, R; Towell, A; Willner, P1
Kantak, KM; Miczek, KA1
Dorce, VA; Palermo-Neto, J1
Czachura, JF; Gonzalez, LP1
Frussa-Filho, R; Palermo-Neto, J1
Martin, JR; Takemori, AE2
Davis, RE; Ellison, G; Sant, WW1
Bläsig, J; Herz, A; Papeschi, R2
Schneider, E; Ziegler, B1
Bläsig, J; Herz, A1
Lal, H; Puri, S1
Drawbaugh, RB; Gianutsos, G; Hynes, MD; Lal, H; Puri, SK1
Hedri, A1
Amitai, M; Dickhaut, HH; Hasenknopf, P1
Lorenzetti, OJ; Sancilio, LF1
Alhava, E; Mansner, R; Mattila, MJ1

Reviews

6 review(s) available for apomorphine and Drug Withdrawal Symptoms

ArticleYear
A Critical Review of Repurposing Apomorphine for Smoking Cessation.
    Assay and drug development technologies, 2015, Volume: 13, Issue:10

    Topics: Apomorphine; Dopamine Agonists; Drug Repositioning; Humans; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder

2015
Substance abuse and movement disorders.
    Current drug abuse reviews, 2009, Volume: 2, Issue:3

    Topics: Alcoholism; Animals; Apomorphine; Humans; Levodopa; Movement Disorders; Parkinson Disease; Substance Withdrawal Syndrome; Substance-Related Disorders

2009
Rapid development of hypersensitivity and hyposensitivity to apomorphine and haloperidol: role of norepinephrine receptor mechanisms in CNS.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Animals; Apomorphine; Behavior, Animal; Brain; Dopamine; Haloperidol; Humans; Norepinephrine; Receptors, Adrenergic; Species Specificity; Substance Withdrawal Syndrome; Time Factors

1980
Narcotic dependence, narcotic action and dopamine receptors.
    Life sciences, 1975, Aug-15, Volume: 17, Issue:4

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Behavior, Animal; Brain; Corpus Striatum; Cyclic AMP; Dopamine; Drug Tolerance; Haloperidol; Humans; Mice; Narcotics; Prostaglandins E; Rats; Receptors, Drug; Substance Withdrawal Syndrome; Substance-Related Disorders; Synaptic Transmission

1975
Aversive therapies for substance abuse: do they work?
    Journal of substance abuse treatment, 1985, Volume: 2, Issue:3

    Topics: Apomorphine; Aversive Therapy; Conditioning, Classical; Desensitization, Psychologic; Electroshock; Emetine; Extinction, Psychological; Humans; Naltrexone; Patient Compliance; Research Design; Substance Withdrawal Syndrome; Substance-Related Disorders; Succinylcholine

1985
[Neurobiologic aspects of the morphine addictions].
    Die Naturwissenschaften, 1974, Volume: 61, Issue:6

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dopamine; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Tolerance; Guinea Pigs; Humans; Mice; Models, Biological; Morphine; Morphine Dependence; Rats; Receptors, Drug; Serotonin; Substance Withdrawal Syndrome

1974

Trials

3 trial(s) available for apomorphine and Drug Withdrawal Symptoms

ArticleYear
Alcohol withdrawal and dopamine receptor sensitivity after prolonged abstinence.
    Progress in neuro-psychopharmacology & biological psychiatry, 1996, Volume: 20, Issue:7

    Topics: Adult; Alcoholism; Apomorphine; Dopamine Agonists; Human Growth Hormone; Humans; Male; Receptors, Dopamine; Substance Withdrawal Syndrome; Temperance

1996
Craving for alcohol and dopamine receptor sensitivity in alcohol-dependent men and control subjects.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:6

    Topics: Adult; Alcoholism; Apomorphine; Brain Chemistry; Conditioning, Psychological; Dopamine; Dopamine Agonists; Human Growth Hormone; Humans; Male; Middle Aged; Odorants; Receptors, Dopamine; Substance Withdrawal Syndrome

2000
[Treatment of abstinence].
    Ugeskrift for laeger, 1976, Oct-11, Volume: 138, Issue:42

    Topics: Alcoholism; Apomorphine; Barbital; Benzodiazepines; Clinical Trials as Topic; Humans; Substance Withdrawal Syndrome

1976

Other Studies

112 other study(ies) available for apomorphine and Drug Withdrawal Symptoms

ArticleYear
Loss of Awareness after Continuous Apomorphine Infusion Withdrawal in Parkinson's Disease.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2020, Volume: 47, Issue:4

    Topics: Aged; Antiparkinson Agents; Apomorphine; Awareness; Humans; Infusions, Intravenous; Lethargy; Male; Parkinson Disease; Substance Withdrawal Syndrome

2020
Acute lethargy after abrupt apomorphine withdrawal in Parkinson's disease.
    Journal of the neurological sciences, 2019, Sep-15, Volume: 404

    Topics: Antiparkinson Agents; Apomorphine; Dopamine Agonists; Humans; Infusions, Subcutaneous; Intraoperative Neurophysiological Monitoring; Lethargy; Male; Middle Aged; Parkinson Disease; Substance Withdrawal Syndrome

2019
Mesoaccumbens dopamine signaling alteration underlies behavioral transition from tolerance to sensitization to morphine rewarding properties during morphine withdrawal.
    Brain structure & function, 2014, Volume: 219, Issue:5

    Topics: Action Potentials; Analgesics, Opioid; Animals; Apomorphine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopaminergic Neurons; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Signal Transduction; Substance Withdrawal Syndrome; Time Factors; Ventral Tegmental Area

2014
Continuous perioperative apomorphine in deep brain stimulation surgery for Parkinson's disease.
    British journal of neurosurgery, 2014, Volume: 28, Issue:3

    Topics: Adult; Aged; Antiparkinson Agents; Apomorphine; Deep Brain Stimulation; Female; Humans; Infusion Pumps; Male; Middle Aged; Nausea; Parkinson Disease; Perioperative Care; Retrospective Studies; Substance Withdrawal Syndrome

2014
Long-term haloperidol treatment (but not risperidone) enhances addiction-related behaviors in mice: role of dopamine D2 receptors.
    Addiction biology, 2009, Volume: 14, Issue:3

    Topics: Amphetamine-Related Disorders; Animals; Antipsychotic Agents; Apomorphine; Corpus Striatum; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Female; Haloperidol; Limbic System; Long-Term Care; Mesencephalon; Mice; Motor Activity; Neural Pathways; Receptors, Dopamine D2; Risperidone; Stereotyped Behavior; Substance Withdrawal Syndrome; Substantia Nigra; Up-Regulation

2009
Dopamine agonist withdrawal syndrome: the apomorphine solution.
    Archives of neurology, 2010, Volume: 67, Issue:9

    Topics: Apomorphine; Dopamine Agonists; Humans; Substance Withdrawal Syndrome

2010
Increased dopamine receptor activity in the nucleus accumbens shell ameliorates anxiety during drug withdrawal.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:11

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anxiety; Apomorphine; Benzazepines; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Male; Morphine; Nucleus Accumbens; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reflex, Startle; Substance Withdrawal Syndrome

2012
Monosialoganglioside (GM1) attenuates the behavioural effects of long-term haloperidol administration in supersensitive rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2004, Volume: 14, Issue:2

    Topics: Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; G(M1) Ganglioside; Haloperidol; Immobilization; Locomotion; Male; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

2004
Neuroendocrinological and neuropsychological correlates of dopaminergic function in nicotine dependence.
    Psychopharmacology, 2004, Volume: 175, Issue:3

    Topics: Adult; Apomorphine; Dopamine D2 Receptor Antagonists; Human Growth Hormone; Humans; Male; Motivation; Neuropsychological Tests; Nicotine; Receptors, Dopamine D2; Smoking; Substance Withdrawal Syndrome; Tobacco Use Disorder

2004
The partial D2-like dopamine receptor agonist terguride acts as a functional antagonist in states of high and low dopaminergic tone: evidence from preweanling rats.
    Psychopharmacology, 2005, Volume: 178, Issue:4

    Topics: Animals; Animals, Newborn; Apomorphine; Body Weight; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Hyperkinesis; Lisuride; Methyltyrosines; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase

2005
Cerebral dopamine function in rats following withdrawal from one year of continuous neuroleptic administration.
    European journal of pharmacology, 1980, May-02, Volume: 63, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Binding Sites; Body Weight; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Male; Motor Activity; Mouth; Movement; Rats; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine; Time Factors; Trifluoperazine

1980
Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia.
    Psychopharmacology, 1980, Volume: 69, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain; Chlorpromazine; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Mouth Diseases; Movement Disorders; Occipital Lobe; Rats; Substance Withdrawal Syndrome

1980
Receptor-mediated dopaminergic function after ethanol withdrawal.
    Alcoholism, clinical and experimental research, 1980, Volume: 4, Issue:3

    Topics: Alcoholism; Animals; Apomorphine; Brain; Dihydroxyphenylalanine; Dopamine; Haloperidol; Humans; Male; Mice; Mice, Inbred C57BL; Receptors, Dopamine; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase

1980
Behavioural and biochemical alterations following haloperidol treatment and withdrawal: the animal model of tardive dyskinesia reexamined.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:2-3

    Topics: Animals; Apomorphine; Behavior, Animal; Brain; Disease Models, Animal; Dopamine; Glutamate Decarboxylase; Haloperidol; Humans; Male; Motor Activity; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase

1983
Neuroendocrine effects of apomorphine in chronic schizophrenic patients under long-term neuroleptic therapy and after drug withdrawal: relations to psychopathology and tardive dyskinesia.
    Psychopharmacology, 1984, Volume: 84, Issue:3

    Topics: Adult; Aged; Antipsychotic Agents; Apomorphine; Chronic Disease; Dyskinesia, Drug-Induced; Female; Growth Hormone; Humans; Male; Prolactin; Schizophrenia; Schizophrenic Psychology; Substance Withdrawal Syndrome; Time Factors

1984
Effects of ethanol administration and withdrawal on neurotransmitter receptor systems in C57 mice.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:3

    Topics: Alcoholism; Animals; Apomorphine; Behavior, Animal; Body Temperature; Humans; Male; Mice; Mice, Inbred C57BL; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Neurotransmitter; Substance Withdrawal Syndrome

1980
Hypophysectomy fails to affect the supersensitivity of striatal dopamine target cells induced by prolonged haloperidol treatment.
    European journal of pharmacology, 1984, Feb-10, Volume: 98, Issue:1

    Topics: Acetylcholine; Animals; Apomorphine; Body Weight; Brain Chemistry; Corpus Striatum; Dopamine; Ergolines; Haloperidol; Humans; Hypophysectomy; Male; Pergolide; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1984
Effects of apomorphine administration on rearing activity of control and experimental rats withdrawn from long-term haloperidol treatment.
    General pharmacology, 1984, Volume: 15, Issue:4

    Topics: Animals; Apomorphine; Haloperidol; Humans; Male; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substance Withdrawal Syndrome

1984
Effects of apomorphine administration on locomotor activity of control and experimental rats withdrawn from long-term haloperidol treatment.
    General pharmacology, 1983, Volume: 14, Issue:5

    Topics: Animals; Apomorphine; Haloperidol; Humans; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substance Withdrawal Syndrome; Time Factors

1983
Spontaneous activity and apomorphine stereotypy during and after withdrawal from 3 1/2 months continuous administration of haloperidol: some methodological issues.
    Psychopharmacology, 1980, Volume: 71, Issue:1

    Topics: Animals; Apomorphine; Body Weight; Haloperidol; Humans; Male; Motor Activity; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1980
Chronic L-DOPA treatment of mice: a behavioural and biochemical study.
    Journal of neural transmission, 1981, Volume: 50, Issue:2-4

    Topics: Animals; Apomorphine; Benserazide; Body Temperature Regulation; Brain; Clonidine; Dihydroxyphenylalanine; Dopamine; Humans; Levodopa; Male; Mice; Motor Activity; Norepinephrine; Substance Withdrawal Syndrome

1981
[Therapy of addicted patients].
    MMW, Munchener medizinische Wochenschrift, 1982, Feb-19, Volume: 124, Issue:7

    Topics: Apomorphine; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders

1982
Influence of lisuride on morphine withdrawal signs in the rat: a dopamine-mimetic effect.
    Psychopharmacology, 1982, Volume: 78, Issue:4

    Topics: Aggression; Animals; Apomorphine; Dopamine; Ergolines; Haloperidol; Humans; Lisuride; Male; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Sulpiride

1982
Differential enhancement of behavioral sensitivity to apomorphine following chronic treatment of rats with (-)-sulpiride and haloperidol.
    European journal of pharmacology, 1982, Jun-16, Volume: 81, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Exploratory Behavior; Haloperidol; Humans; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Sulpiride

1982
Differential liabilities of haloperidol and thioridazine for inducing apomorphine hypersensitivity.
    Biological psychiatry, 1982, Volume: 17, Issue:11

    Topics: Animals; Apomorphine; Benztropine; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Humans; Limbic System; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine

1982
Treatment of alcohol withdrawal symptoms.
    British journal of hospital medicine, 1982, Volume: 28, Issue:1

    Topics: Alcoholism; Apomorphine; Humans; Substance Withdrawal Syndrome

1982
Estrogen in experimental tardive dyskinesia.
    Neurology, 1980, Volume: 30, Issue:5

    Topics: Animals; Apomorphine; Castration; Dyskinesia, Drug-Induced; Estradiol; Female; Haloperidol; Humans; Rats; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome

1980
Tolerance to fluphenazine and supersensitivity to apomorphine in central dopaminergic systems after chronic fluphenazine decanoate treatment.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 312, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Fluphenazine; Haloperidol; Homovanillic Acid; Humans; Male; Olfactory Bulb; Rats; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1980
Changes in cerebral dopamine function induced by a year's administration of trifluoperazine or thioridazine and their subsequent withdrawal.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Brain; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Humans; Male; Rats; Spiperone; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine; Time Factors; Trifluoperazine

1980
Antagonism of dopamine supersensitivity by estrogen: neurochemical studies in an animal model of tardive dyskinesia.
    Biological psychiatry, 1981, Volume: 16, Issue:4

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Estradiol; Female; Haloperidol; Humans; Rats; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome

1981
[Effect of psychotropic drugs on sleep disorders in rats during alcohol withdrawal].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 91, Issue:6

    Topics: Alcoholism; Animals; Anti-Anxiety Agents; Apomorphine; Benzodiazepines; Benzodiazepinones; Haloperidol; Humans; Male; Psychotropic Drugs; Rats; Sleep Wake Disorders; Sodium Oxybate; Substance Withdrawal Syndrome

1981
Subsensitivity of the presynaptic dopamine receptors in cat heart after the termination of chronic haloperidol treatment.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 253, Issue:2

    Topics: Animals; Apomorphine; Blood Pressure; Cats; Female; Haloperidol; Heart; Humans; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Receptors, Dopamine; Substance Withdrawal Syndrome; Tyramine

1981
[New approach to treating chronic alcoholism].
    Sovetskaia meditsina, 1980, Issue:1

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Apomorphine; Dopamine; Dopamine Antagonists; Drug Evaluation; Humans; Male; Substance Withdrawal Syndrome

1980
Ethanol withdrawal does not induce a reduction in the number of spontaneously active dopaminergic neurons in the mesolimbic system.
    Brain research, 1995, Jun-05, Volume: 682, Issue:1-2

    Topics: Anesthesia; Animals; Apomorphine; Chloral Hydrate; Dopamine; Dopamine Agonists; Ethanol; Limbic System; Male; Neurons; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Ventral Tegmental Area

1995
Dopaminergic responsivity in alcoholism: trait, state, or residual marker?
    The American journal of psychiatry, 1995, Volume: 152, Issue:9

    Topics: Adult; Alcohol Drinking; Alcoholism; Apomorphine; Biomarkers; Ethanol; Female; Growth Hormone; Humans; Longitudinal Studies; Male; Middle Aged; Severity of Illness Index; Substance Withdrawal Syndrome

1995
Differential involvement of voltage-dependent calcium channels in apomorphine-induced hypermotility and stereotypy.
    Psychopharmacology, 1994, Volume: 113, Issue:3-4

    Topics: Animals; Apomorphine; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Electroshock; Male; Morphine; Motor Activity; Nifedipine; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome; Up-Regulation

1994
Subchronic treatment with haloperidol and clozapine in rats with neonatal excitotoxic hippocampal damage.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1994, Volume: 10, Issue:3

    Topics: Animals; Animals, Newborn; Apomorphine; Clozapine; Female; Haloperidol; Hippocampus; Ibotenic Acid; Motor Activity; Neurotoxins; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome

1994
Time-dependent changes in sensitivity to apomorphine and monoamine receptors following withdrawal from continuous cocaine administration in rats.
    Synapse (New York, N.Y.), 1994, Volume: 16, Issue:1

    Topics: Animals; Apomorphine; Autoradiography; Behavior, Animal; Brain; Cocaine; Male; Motor Activity; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1994
Withdrawal from continuous or intermittent cocaine administration: changes in D2 receptor function.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger; Substance Withdrawal Syndrome

1994
The effects of acute levodopa withdrawal on motor performance and dopaminergic receptor sensitivity in patients with Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1993, Volume: 56, Issue:7

    Topics: Aged; Apomorphine; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Psychomotor Performance; Receptors, Dopamine; Substance Withdrawal Syndrome

1993
Apomorphine SC treatment in parkinsonian patients with long-term L-dopa syndrome during L-dopa drug holiday.
    Journal of neural transmission. Supplementum, 1995, Volume: 45

    Topics: Adult; Aged; Antiparkinson Agents; Apomorphine; Dihydroxyphenylalanine; Dopamine Agents; Drug Administration Schedule; Humans; Infusions, Parenteral; Middle Aged; Risk Factors; Skin; Substance Withdrawal Syndrome

1995
Differences between haloperidol- and pimozide-induced withdrawal syndrome: a role for Ca2+ channels.
    European journal of pharmacology, 1995, Dec-29, Volume: 294, Issue:2-3

    Topics: Animals; Antipsychotic Agents; Apomorphine; Calcium Channels; Haloperidol; Male; Motor Activity; Nifedipine; Nitrendipine; Pimozide; Rats; Rats, Wistar; Receptors, Dopamine D1; Substance Withdrawal Syndrome

1995
Differential effects of SCH 23390 on the apomorphine subsensitivity in the substantia nigra and ventral tegmental area 1 day following withdrawal from continuous or intermittent cocaine pretreatment.
    Brain research, 1997, Jan-09, Volume: 744, Issue:2

    Topics: Animals; Apomorphine; Benzazepines; Cocaine; Male; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substantia Nigra; Tegmentum Mesencephali

1997
Differential influence of D1 and D2 dopamine receptors on acute opiate withdrawal in guinea-pig isolated ileum.
    British journal of pharmacology, 1997, Volume: 120, Issue:6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Apomorphine; Dopamine Agents; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Haloperidol; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Pyrrolidines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome

1997
Behavioural subsensitivity induced by long-term administration of a low dose of haloperidol to rats.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:4

    Topics: Administration, Oral; Animals; Apomorphine; Autoreceptors; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Haloperidol; Injections, Intraperitoneal; Locomotion; Male; Random Allocation; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome

1997
Responses to propofol in relation to GABA functionality of discrete parts of the brain of rats.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:4

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Apomorphine; Behavior, Animal; Blood Pressure; Brain; Female; gamma-Aminobutyric Acid; Heart Rate; Propofol; Rats; Rats, Wistar; Reflex; Substance Withdrawal Syndrome; Synaptic Transmission

1997
Influence of the dopamine D2 receptor (DRD2) genotype on neuroadaptive effects of alcohol and the clinical outcome of alcoholism.
    Pharmacogenetics, 1997, Volume: 7, Issue:4

    Topics: Adaptation, Physiological; Adult; Aged; Alcoholism; Apomorphine; Female; Follow-Up Studies; Genotype; Human Growth Hormone; Humans; Male; Middle Aged; Polymerase Chain Reaction; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Suicide, Attempted

1997
The role of dopamine in the expression of morphine withdrawal.
    General pharmacology, 1998, Volume: 30, Issue:4

    Topics: Adrenergic Agents; Analgesia; Analgesics, Opioid; Analysis of Variance; Animals; Apomorphine; Dopamine; Dopamine Agents; Dopamine Antagonists; Hypothermia; Levodopa; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Oxidopamine; Substance Withdrawal Syndrome

1998
Monosialoganglioside increased the in vivo affinity of D2 receptors for apomorphine in supersensitive rats.
    Annals of the New York Academy of Sciences, 1998, Jun-19, Volume: 845

    Topics: Animals; Antipsychotic Agents; Apomorphine; Corpus Striatum; G(M1) Ganglioside; Haloperidol; Kinetics; Metoclopramide; Rats; Receptors, Dopamine D2; Stereotyped Behavior; Substance Withdrawal Syndrome

1998
Altered activity of midbrain dopamine neurons following 7-day withdrawal from chronic cocaine abuse is normalized by D2 receptor stimulation during the early withdrawal phase.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:1

    Topics: Animals; Apomorphine; Benzazepines; Cocaine-Related Disorders; Dopamine; Dopamine Agonists; Dopamine Antagonists; Electrophysiology; Male; Mesencephalon; Neurons; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Substantia Nigra; Ventral Tegmental Area

1999
Modification of naloxone-induced withdrawal signs by dextromethorphan in morphine-dependent mice.
    European journal of pharmacology, 1999, Jul-14, Volume: 377, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Benzazepines; Dextromethorphan; Domperidone; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Grooming; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Pain; Substance Withdrawal Syndrome; Sulpiride

1999
Behavioral activation induced by D(2)-like receptor stimulation during opiate withdrawal.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:2

    Topics: Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Locomotion; Male; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereotyped Behavior; Substance Withdrawal Syndrome

2000
Expression of fos-related antigens in the nucleus accumbens during opiate withdrawal and their attenuation by a D2 dopamine receptor agonist.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Immunohistochemistry; Lithium Chloride; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Substance Withdrawal Syndrome

2000
Genetic analysis of the mu-opioid receptor in alcohol-dependent individuals.
    Alcohol (Fayetteville, N.Y.), 2001, Volume: 24, Issue:2

    Topics: Adult; Alcoholism; Alleles; Apomorphine; Dopamine Agonists; Exploratory Behavior; Female; Gene Frequency; Human Growth Hormone; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptors, Opioid, mu; Substance Withdrawal Syndrome

2001
Effect of apomorphine on the antinociceptive activity of morphine.
    Psychopharmacology, 1977, Jun-06, Volume: 53, Issue:1

    Topics: Analgesics, Opioid; Animals; Apomorphine; Drug Synergism; Drug Tolerance; Female; Humans; Male; Mice; Morphine; Nalorphine; Rats; Rats, Inbred Strains; Reaction Time; Substance Withdrawal Syndrome; Time Factors

1977
Behavioural correlates of modified dopaminergic/anticholinergic responses following chronic treatment with neuroleptic agents of differing activity spectra.
    European journal of pharmacology, 1978, Mar-01, Volume: 48, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Body Weight; Dexetimide; Dopamine; Exploratory Behavior; Humans; Male; Motor Activity; Parasympatholytics; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1978
[Comparisons between the effects of apomorphine and naloxone in acutely dependent morphinized rats and mice (author's transl)].
    Psychopharmacology, 1978, Sep-15, Volume: 59, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Humans; Male; Methyltyrosines; Mice; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome; Time Factors

1978
The effect of chronic administration and withdrawal of amphetamine on cerebral dopamine receptor sensitivity.
    Psychopharmacology, 1978, Jul-06, Volume: 58, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Biogenic Amines; Brain; Brain Chemistry; Dextroamphetamine; Drug Interactions; Humans; Male; Mice; Mice, Inbred Strains; Receptors, Dopamine; Substance Withdrawal Syndrome; Time Factors

1978
Prostaglandins, cyclic AMP and the mechanism of opiate dependence.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Brain; Cattle; Codeine; Cyclic AMP; Humans; In Vitro Techniques; Male; Morphine; Morphine Dependence; Naloxone; Prostaglandins; Rats; Seminal Vesicles; Substance Withdrawal Syndrome; Substance-Related Disorders; Tissue Extracts

1975
Cyclic GMP and GABA levels in rat striatum and cerebellum during morphine withdrawal: effect of apomorphine.
    Neuropharmacology, 1977, Volume: 16, Issue:11

    Topics: Aminobutyrates; Animals; Apomorphine; Brain Chemistry; Cerebellum; Corpus Striatum; Cyclic GMP; gamma-Aminobutyric Acid; Humans; Male; Morphine Dependence; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1977
Site of naloxone-precipitated opiate withdrawal dissociates from that at which apomorphine reinitiates this phenomenon.
    Naunyn-Schmiedeberg's archives of pharmacology, 1978, Volume: 305, Issue:1

    Topics: Animals; Apomorphine; Clonidine; Humans; Injections, Intraventricular; Male; Naloxone; Rats; Receptors, Opioid; Substance Withdrawal Syndrome

1978
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Dexetimide; Dextromoramide; Dogs; Dopamine; Drug Combinations; Haloperidol; Humans; Meperidine; Methadone; Mice; Morphine; Phenoperidine; Pimozide; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome; Tranquilizing Agents; Vomiting

1975
Interactions of thyrotropin releasing hormone and morphine sulfate in rodents.
    Life sciences, 1977, Feb-15, Volume: 20, Issue:4

    Topics: Analgesics; Animals; Apomorphine; Behavior, Animal; Body Weight; Chlorpromazine; Dronabinol; Humans; Mice; Morphinans; Morphine; Pain; Pentobarbital; Rats; Substance Withdrawal Syndrome; Thyrotropin-Releasing Hormone

1977
Effects of withdrawal from chronic amphetamine intoxication on exploratory and stereotyped behaviors in the rat.
    Psychopharmacology, 1977, Nov-15, Volume: 54, Issue:3

    Topics: Animals; Apomorphine; Behavior; Dextroamphetamine; Exploratory Behavior; Humans; Male; Methyltyrosines; Rats; Reserpine; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1977
Enhanced prolactin inhibition following chronic treatment with haloperidol and morphine.
    Life sciences, 1977, Jan-01, Volume: 20, Issue:1

    Topics: Animals; Apomorphine; Dopamine; Haloperidol; Humans; Hypothalamus; Male; Morphine; Neural Pathways; Prolactin; Rats; Substance Withdrawal Syndrome; Thalamus

1977
Dopaminergic mechanisms in precipitated withdrawal in morphine-dependent rats.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:2

    Topics: Animals; Apomorphine; Body Temperature; Dopamine; Drug Interactions; Humans; Male; Morphine Dependence; Naloxone; Pimozide; Rats; Substance Withdrawal Syndrome; Time Factors

1977
Influence of morphine dependence and withdrawal on circling behaviour in rats with unilateral nigral lesions [proceedings].
    British journal of pharmacology, 1977, Volume: 59, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Humans; Male; Morphine; Morphine Dependence; Rats; Rotation; Substance Withdrawal Syndrome; Substantia Nigra

1977
Changes in sensitivity to operant effects of dopaminergic and cholinergic agents following morphine withdrawal in rats.
    European journal of pharmacology, 1977, Apr-07, Volume: 42, Issue:3

    Topics: Animals; Apomorphine; Conditioning, Operant; Dopamine; Female; Haloperidol; Humans; Morphine; Pilocarpine; Rats; Reinforcement Schedule; Scopolamine; Substance Withdrawal Syndrome; Time Factors

1977
Effect of chronic chlorpromazine administration or prior treatment with reserpine on brain apomorphine concentrations and apomorphine-induced sterotyped behaviour in the rat.
    European journal of pharmacology, 1977, May-15, Volume: 43, Issue:2

    Topics: Animals; Apomorphine; Behavior; Brain Chemistry; Chlorpromazine; Drug Interactions; Humans; Male; Motor Activity; Rats; Reserpine; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1977
Effect of apomorphine and its N-propyl homologue on ethanol withdrawal head twitches in mice.
    British journal of pharmacology, 1977, Volume: 61, Issue:4

    Topics: Alcoholism; Animals; Apomorphine; Humans; Male; Mice; Substance Withdrawal Syndrome

1977
Changes in sensitivity to apomorphine during morphine dependence and withdrawal in rats.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 196, Issue:3

    Topics: Animals; Apomorphine; Dopamine; Humans; Male; Morphine Dependence; Naloxone; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1976
[Apomorphine treatment of withdrawal symptoms in young opiate addicts].
    Ugeskrift for laeger, 1976, Oct-11, Volume: 138, Issue:42

    Topics: Adolescent; Adult; Apomorphine; Hospitalization; Humans; Injections, Subcutaneous; Morphine Dependence; Opium; Substance Withdrawal Syndrome

1976
Dopaminergic-cholinergic interactions in naloxone-induced circling in morphine-dependent rats with nigral lesions.
    European journal of pharmacology, 1976, Volume: 38, Issue:1

    Topics: Animals; Apomorphine; Arecoline; Atropine; Behavior; Dopamine; Humans; Hydroxydopamines; Male; Morphine Dependence; Naloxone; Parasympathetic Nervous System; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Substantia Nigra

1976
Enhancement of morphine-withdrawal and apomorphine-induced aggression by clonidine.
    Psychopharmacology communications, 1976, Volume: 2, Issue:2

    Topics: Aggression; Animals; Apomorphine; Clonidine; Humans; Male; Morphine; Rats; Stimulation, Chemical; Substance Withdrawal Syndrome; Vocalization, Animal

1976
Dopaminergic sites involved in morphine withdrawal hypothermia.
    Proceedings of the Western Pharmacology Society, 1976, Volume: 19

    Topics: Animals; Apomorphine; Body Temperature; Dopamine; Drug Implants; Humans; Hypothalamus; Injections; Male; Morphine; Naloxone; Pimozide; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome

1976
Dopaminergic influence on withdrawal jumping behavior in morphine-dependent mice.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 15, Issue:3

    Topics: Animals; Apomorphine; Brain; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Methyltyrosines; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Morphine Dependence; Motor Activity; Naloxone; Species Specificity; Substance Withdrawal Syndrome

1976
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:1

    Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Injections, Intraperitoneal; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotics; Pentazocine; Substance Withdrawal Syndrome

1975
Dopaminergic mechanisms in withdrawal hypothermia in morphine dependent rats.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Animals; Apomorphine; Dopamine; Humans; Hypothermia; Male; Morphine; Naloxone; Pimozide; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1975
Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine.
    Psychopharmacologia, 1975, Volume: 41, Issue:2

    Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzazepines; Dibenzoxazepines; Disease Models, Animal; Dopamine; Drug Tolerance; Female; Haloperidol; Homovanillic Acid; Humans; Loxapine; Male; Movement Disorders; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome

1975
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
    Psychopharmacologia, 1975, Jun-19, Volume: 42, Issue:3

    Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome

1975
Paradoxical absence of aggression during naloxone-precipitated morphine withdrawal.
    Psychopharmacologia, 1975, Jul-23, Volume: 43, Issue:1

    Topics: Aggression; Animals; Apomorphine; Dextroamphetamine; Humans; Male; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome

1975
Supersensitivity to dopaminergic agonists induced by haloperidol.
    National Institute on Drug Abuse research monograph series, 1975, Issue:3

    Topics: Animals; Apomorphine; Diet; Dopamine; Drug Interactions; Haloperidol; Humans; Male; Mice; Motor Activity; Pimozide; Receptors, Drug; Substance Withdrawal Syndrome

1975
[Electrolyte metabolism in alcoholic patients during therapy and prolonged abstinence].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:2

    Topics: Adrenal Cortex; Adrenal Insufficiency; Adult; Alcoholism; Apomorphine; Disulfiram; Erythrocytes; Humans; Middle Aged; Mineralocorticoids; Potassium; Sodium; Substance Withdrawal Syndrome

1976
Activation of the zinc finger encoding gene krox-20 in adult rat brain: comparison with zif268.
    Brain research. Molecular brain research, 1992, Volume: 13, Issue:3

    Topics: Animals; Apomorphine; Benzazepines; Brain; DNA-Binding Proteins; Early Growth Response Protein 1; Early Growth Response Protein 2; Electroshock; Haloperidol; Immediate-Early Proteins; Male; Morphine; Naltrexone; Nucleic Acid Hybridization; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Seizures; Substance Withdrawal Syndrome; Transcription Factors; Transcription, Genetic; Zinc Fingers

1992
Effect of D1 and D2 agonists in primates withdrawn from long-term treatment with haloperidol: the potential role of dopamine D1 receptors in dyskinesia.
    Clinical neuropharmacology, 1992, Volume: 15, Issue:6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Cebus; Dopamine Agents; Dyskinesia, Drug-Induced; Ergolines; Female; Grooming; Haloperidol; Hypnotics and Sedatives; Male; Motor Activity; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Substance Withdrawal Syndrome

1992
The progressive changes of neuronal activities of the nigral dopaminergic neurons upon withdrawal from continuous infusion of cocaine.
    Brain research, 1992, Oct-30, Volume: 594, Issue:2

    Topics: Animals; Apomorphine; Cocaine; Dopamine; Male; Neurons; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substantia Nigra

1992
Apomorphine in malignant syndrome due to levodopa withdrawal.
    Italian journal of neurological sciences, 1992, Volume: 13, Issue:2

    Topics: Aged; Apomorphine; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome

1992
Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance.
    Brain research, 1991, Dec-24, Volume: 568, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Carbidopa; Corpus Striatum; Denervation; Drug Tolerance; Functional Laterality; Homovanillic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1991
Behavioural and biochemical effects of subchronic treatment with raclopride in the rat: tolerance and brain monoamine receptor sensitivity.
    Pharmacology & toxicology, 1991, Volume: 68, Issue:4

    Topics: Animals; Apomorphine; Brain; Dihydroxyphenylalanine; Dopamine Antagonists; Drug Tolerance; Male; Motor Activity; Raclopride; Rats; Rats, Inbred Strains; Reserpine; Salicylamides; Substance Withdrawal Syndrome; Time Factors

1991
Dopaminergic sensitivity and cocaine abuse: response to apomorphine.
    Psychiatry research, 1990, Volume: 33, Issue:2

    Topics: Adult; Anxiety; Apomorphine; Attention; Brain; Cocaine; Dopamine; Homovanillic Acid; Humans; Male; Prolactin; Receptors, Dopamine; Substance Withdrawal Syndrome; Substance-Related Disorders

1990
A10 somatodendritic dopamine autoreceptor sensitivity following withdrawal from repeated cocaine treatment.
    Neuroscience letters, 1990, Sep-04, Volume: 117, Issue:1-2

    Topics: Animals; Apomorphine; Brain; Cocaine; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Salicylamides; Substance Withdrawal Syndrome; Substance-Related Disorders

1990
The effect of chronic lithium administration and withdrawal on locomotor activity and apomorphine-induced locomotor stimulation in rats.
    Journal of neural transmission, 1988, Volume: 71, Issue:1

    Topics: Animals; Apomorphine; Chlorides; Exploratory Behavior; Lithium; Lithium Chloride; Male; Motor Activity; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Time Factors

1988
Prolonged pharmacologic activity of neuroleptics.
    Archives of general psychiatry, 1985, Volume: 42, Issue:6

    Topics: Animals; Antipsychotic Agents; Apomorphine; Dose-Response Relationship, Drug; Half-Life; Haloperidol; Humans; Kinetics; Rats; Risk; Stereotyped Behavior; Substance Withdrawal Syndrome

1985
Changes in dopamine receptor sensitivity in humans after heavy alcohol intake.
    Psychopharmacology, 1985, Volume: 86, Issue:1-2

    Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anticonvulsants; Apomorphine; Benzodiazepines; Chlormethiazole; Ethanol; Female; Growth Hormone; Humans; Male; Middle Aged; Pituitary Gland, Anterior; Receptors, Dopamine; Substance Withdrawal Syndrome

1985
[Dopamine receptor stimulants in the treatment of alcoholism].
    Sovetskaia meditsina, 1988, Issue:8

    Topics: Alcoholism; Apomorphine; Bromocriptine; Dopamine; Dopamine Agents; Drug Evaluation; Ethanol; Humans; Male; Substance Withdrawal Syndrome

1988
Dopamine autoreceptors in the ventral tegmental area show subsensitivity following withdrawal from chronic antidepressant drug treatment.
    Psychopharmacology, 1986, Volume: 90, Issue:1

    Topics: Animals; Antidepressive Agents; Apomorphine; Desipramine; Feeding Behavior; Male; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome; Tegmentum Mesencephali

1986
Social, motor, and autonomic signs of morphine withdrawal: differential sensitivities to catecholaminergic drugs in mice.
    Psychopharmacology, 1988, Volume: 96, Issue:4

    Topics: Animals; Apomorphine; Autonomic Nervous System; Catecholamines; Clonidine; Cocaine; Dextroamphetamine; Levodopa; Mice; Mice, Inbred Strains; Morphine Dependence; Psychomotor Performance; Reaction Time; Social Behavior; Substance Withdrawal Syndrome

1988
Effects of ovariectomy and of estrogen administration on some dopamine-related behaviors in the rat.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1988, Volume: 21, Issue:2

    Topics: Analysis of Variance; Animals; Apomorphine; Estradiol; Female; Haloperidol; Ovariectomy; Random Allocation; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substance Withdrawal Syndrome; Task Performance and Analysis

1988
Ethanol withdrawal alters apomorphine-induced motility.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:1

    Topics: Animals; Apomorphine; Ethanol; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome

1988
Effects of single and long-term metoclopramide administration on open field and stereotyped behavior of rats.
    European journal of pharmacology, 1988, May-10, Volume: 149, Issue:3

    Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Male; Metoclopramide; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substance Withdrawal Syndrome

1988
Modification of the development of acute opiate tolerance by increased dopamine receptor sensitivity.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Drug Interactions; Drug Tolerance; Levorphanol; Lithium; Male; Mice; Morphine; Naloxone; Narcotics; Opioid-Related Disorders; Receptors, Dopamine; Spiperone; Substance Withdrawal Syndrome

1987
Chronically administered morphine increases dopamine receptor sensitivity in mice.
    European journal of pharmacology, 1986, Feb-18, Volume: 121, Issue:2

    Topics: Analgesia; Animals; Apomorphine; Behavior, Animal; Binding Sites; Brain; Drug Implants; Drug Tolerance; Hypothermia; Lithium; Male; Mice; Morphine; Naloxone; Receptors, Dopamine; Spiperone; Substance Withdrawal Syndrome

1986
Continuous low-level apomorphine administration induces motor abnormalities and hallucinogen-like behaviors.
    Psychopharmacology, 1985, Volume: 85, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Dopamine; Drug Implants; Hallucinogens; Humans; Injections, Subcutaneous; Male; Motor Activity; Rats; Rats, Inbred Strains; Serotonin; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1985
[Significance of catecholamines for the manifestation of morphine withdrawal in the rat].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:7

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Catecholamines; Desipramine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Humans; Levallorphan; Methyltyrosines; Morphine; Morphine Dependence; Motor Activity; Norepinephrine; Rats; Substance Withdrawal Syndrome

1974
Role of catecholaminergic mechanisms in the expression of the morphine abstinence syndrome in rats.
    Psychopharmacologia, 1974, Volume: 39, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Benserazide; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Eye Movements; Humans; Levallorphan; Male; Methyltyrosines; Morphine; Morphine Dependence; Motor Activity; Nasal Mucosa; Norepinephrine; Piperazines; Rats; Serotonin; Substance Withdrawal Syndrome

1974
[Treatment of withdrawal syndrome with apomorphine].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Apomorphine; Humans; Injections, Subcutaneous; Male; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders

1974
Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression.
    Psychopharmacologia, 1973, Volume: 32, Issue:2

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Dihydroxyphenylalanine; Haloperidol; Humans; Male; Methadone; Methyltyrosines; Morphine Dependence; Premedication; Rats; Substance Withdrawal Syndrome

1973
Effect of apomorphine and nigrostriatal lesions on aggression and striatal dopamine turnover during morphine withdrawal: evidence for dopaminergic supersensitivity in protracted abstinence.
    Psychopharmacologia, 1974, Jan-09, Volume: 34, Issue:1

    Topics: Aggression; Animals; Apomorphine; Corpus Striatum; Dopamine; Humans; Male; Morphine; Rats; Substance Withdrawal Syndrome; Substantia Nigra; Time Factors

1974
[Apomorphine in opiate withdrawal treatment].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1972, Apr-11, Volume: 61, Issue:15

    Topics: Adult; Apomorphine; Humans; Male; Morphine Dependence; Substance Withdrawal Syndrome

1972
[Therapy of withdrawal symptoms in "fixers". (Drug abuse of adolescents by intravenous injection)].
    Der Nervenarzt, 1972, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Anxiety; Apomorphine; Female; Hallucinations; Humans; Male; Morphine Dependence; Psychotherapy; Substance Withdrawal Syndrome

1972
Morphine dependent rats as a model for evaluating potential addiction liability of analgesic compounds.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 183, Issue:2

    Topics: Analgesics; Animals; Apomorphine; Azepines; Behavior, Animal; Codeine; Dextropropoxyphene; Diphenhydramine; Histamine; Humans; Meperidine; Meprobamate; Methadone; Methods; Morphine Dependence; Pentazocine; Pyrrolidines; Rats; Salicylates; Serotonin; Substance Withdrawal Syndrome

1970
Modification by disulfiram or methyltyrosine methylester (H 44-68) of abstinence symptoms in morphine-tolerant rats.
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:9

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Depression, Chemical; Disulfiram; Dopamine; Drug Synergism; Drug Tolerance; Esters; Female; Humans; Male; Methyltyrosines; Morphine; Myocardium; Nalorphine; Norepinephrine; Rats; Stimulation, Chemical; Substance Withdrawal Syndrome

1968