Page last updated: 2024-08-17

apomorphine and Disease Models, Animal

apomorphine has been researched along with Disease Models, Animal in 478 studies

Research

Studies (478)

TimeframeStudies, this research(%)All Research%
pre-199067 (14.02)18.7374
1990's63 (13.18)18.2507
2000's147 (30.75)29.6817
2010's180 (37.66)24.3611
2020's21 (4.39)2.80

Authors

AuthorsStudies
Bhatia, P; Brioni, JD; Chang, R; Donnelly-Roberts, DL; El Kouhen, O; Hakeem, AA; Henry, R; Hollingsworth, PR; Hsieh, GC; Kolasa, T; Marsh, KC; Martino, B; Matulenko, MA; Miller, LN; Moreland, RB; Mortell, K; Nakane, M; Namovic, MT; Patel, MV; Stewart, AO; Terranova, MA; Uchic, ME; Wetter, JM1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Fan, F; Liu, S; Wang, Y; Zheng, Y; Zhou, J1
Mohajeri, D; Nourazar, MA; Sokouti, H1
Chan, P; Ding, H; Liu, Y; Ren, Z; Yang, N; Zhou, M1
Cañete, T; Corda, MG; Fernández-Teruel, A; Giorgi, O; Oliveras, I; Río-Álamos, C; Sampedro-Viana, D; Tobeña, A1
Bilal, B; Erbas, O; Erdogan, MA; Kirazlar, M; Yigitturk, G1
Alam, M; Elle, T; John, N; Krauss, JK; Schwabe, K; Voigt, C1
Tian, H; Xiao, W; Xue, B1
Abd-Elrahman, KS; Bureau, SC; Derksen, A; Dwyer, Z; Farmer, K; Ferguson, SSG; Fortin, T; Hayley, S; Prowse, NA; Rowe, EM; Rudyk, CA; Thompson, AM1
Botha, TL; Brand, SJ; de Brouwer, G; Finger-Baier, K; van Staden, C; Wolmarans, D1
Dravid, SM; Gakare, SG; Gawai, P; Sarode, L; Ugale, RR; Upadhyay, R1
da Costa, RO; de Araújo, DP; de Barros Viana, GS; de Lucena, JD; Gadelha-Filho, CVJ; Lima, FAV; Neves, KRT1
Balenovic, I; Blagaic, AB; Cilic, M; Drmic, D; Filipcic, I; Ilic, S; Kokot, A; Seiwerth, S; Sikiric, P; Strbe, S; Tvrdeic, A; Vukojevic, J; Zemba Cilic, A; Zemba, M; Zoricic, Z1
Fu, X; Liu, J; Lu, XJ; Sun, Y; Xia, CL; Zhan, Y; Zhang, Y; Zhao, L1
Galabov, AS; Stoyanova, A1
Ahmed, S; Haleem, DJ; Ikram, H1
Costa, G; Marongiu, J; Morelli, M; Serra, M; Simola, N1
Abuirmeileh, AN; Alzoubi, KH; Rababa'h, AM1
Deev, A; Nebogatikov, V; Sengpiel, F; Ustyugov, AA; Vorobyov, V1
Abuhamdah, SM; Abuirmeileh, AN; Alzoubi, KH; Ashraf, A1
Antipova, V; Hawlitschka, A; Holzmann, C; Witt, M; Wree, A1
Funamizu, Y; Mizukami, H; Nishijima, H; Tomiyama, M; Ueno, S; Ueno, T; Yagihashi, S1
Aldana, L; Berlanga, J; Garcia Del Barco, D; Perez-Saad, H; Subiros, N1
Nemas, M; Nyska, A; Ramot, Y; Rubinski, A; Schiffenbauer, YS; Shaltiel-Karyo, R; Tsarfati, Y; Weinstock, I; Yacoby-Zeevi, O; Zawoznik, E1
Alam, M; Grothe, C; Jin, X; Krauss, JK; Ratzka, A; Rumpel, R; Schwabe, K; Tschirner, SK; von Wrangel, C1
Iinuma, KM; Imamura, T; Kira, JI; Murai, H; Nakamura, N; Ohyagi, Y; Soejima, N; Yamasaki, R; Yanagihara, YT1
Pandy, V; Vijeepallam, K1
Adjei, S; Amoateng, P; Karikari, TK; Kukuia, KKE; Nyarko, AK; Osei-Safo, D1
Adjei, S; Amoateng, P; Bekoe, EO; Karikari, TK; Kombian, SB; Kukuia, KKE; Osei-Safo, D1
Jaehne, EJ; Lee, JJW; van den Buuse, M1
Aderibigbe, AO; Ajayi, AM; Ben-Azu, B; Iwalewa, EO; Omogbiya, IA1
Ai, Y; Andersen, AH; Evans, A; Forman, E; Gash, DM; Grondin, R; Hardy, PA; Yue, G; Yue, J; Zhang, R; Zhang, Z1
Chen, YH; Gou, Y; Li, HW; Li, Y; Lin, X; Tang, L; Wen, M; Zhang, Y; Zhou, B1
Açikalin, Ö; Bölükbaşi Hatip, F; Hatip-Al-Khatib, I; Kataoka, Y; Tan, R; Yamauchi, A1
Ando, K; Inoue, R; Kawai, K; Nishime, C; Nishinaka, E; Tsutsumi, H; Urano, K1
Christensen, KV; Christoffersen, CT; Clausen, D; Didriksen, M; Egebjerg, J; Fejgin, K; Kallunki, P; Larsen, PH; Lauridsen, JB; Mørk, A; Nielsen, J; Nielsen, V; Sotty, F; Werge, TM; Yavich, L1
Bozza, G; Busceti, CL; Fornai, F; Gaglione, A; Mastroiacovo, F; Nicoletti, F; Orzi, F; Ryskalin, L1
Babayan-Tazehkand, A; Haghdoost-Yazdi, H; Rastgoo, N; Sarbazi-Golezari, A; Sarookhani, MR1
Chen, G; Chen, J; Chen, Y; Dai, Y; Jiang, H; Yang, B; Yu, W; Zang, F; Zhu, L1
Bjarkam, CR; Christensen, AB; Ettrup, KS; Orlowski, D; Sørensen, JCH1
de Campos, PS; Hasegawa, K; Kawamura, LRSM; Kumei, Y; Zeredo, JL1
Liu, J; Wang, X; Wang, Y1
Du, CX; Liu, J; Sun, YN; Wang, HS; Wang, Y; Yao, L; Zhang, GJ; Zhang, L1
Babayan-Tazehkand, A; Dargahi, T; Haghdoost-Yazdi, H; Rastgoo, N; Sarbazi Golezari, A; Sarukhani, M1
Dohgu, S; Fukae, J; Kataoka, Y; Koga, M; Matsumoto, J; Nakashima, A; Takata, F; Tsuboi, Y; Yamauchi, A1
Chen, J; Huang, F; Li, Q; Qu, J; Wang, Q; Wu, Y; Yang, Y; Zhang, L; Zhou, X1
Chan, MH; Chang, PC; Chen, C; Chen, HH1
Anderson, KA; Bhupal, PK; Dunbar, GL; Hoolsema, KS; Lynn, JD; Rossignol, J; Sandstrom, MI; Shall, GP1
Du, CX; Guo, Y; Liu, J; Lv, SX; Zhang, J; Zhang, QJ1
Li, K; Li, Y; Na, S; Wu, J; Xie, X; Yang, J; Yang, Z; Yu, X; Yue, J1
Chen, L; Cheng, L; Gao, C; Liu, H; Ren, Z; Wang, Y; Wei, X; Wen, H; Zeng, S; Zhang, X1
Andrade, GM; Calou, IBF; Costa, RO; Lima, FAV; Lima, LAR; Lopes, MJP; Neves, KRT; Viana, GSB1
Gill, KM; Grace, AA; Sonnenschein, SF1
Chen, G; Chen, J; Chen, Y; Dai, Y; Yang, B; Yu, W1
Brito, BM; Gobira, PH; Joca, SRL; Sartim, AG1
Choudhury, ME; Kubo, M; Miyanishi, K; Nomoto, M; Tanaka, J; Watanabe, M; Yano, H1
Brosch, M; Coors, A; Fendt, M; Franke, K; Gerber, B; Kahl, E; Khalil, R; Laub, A; Michels, B1
Bakharev, B; Bobkova, N; Deev, A; Medvinskaya, N; Nesterova, I; Samokhin, A; Sengpiel, F; Tatarnikova, O; Ustyugov, AA; Vorobyov, V1
Antonio, CB; Betti, AH; da Rocha Pitta, I; do Rego, JC; do Rego, JL; Herzfeldt, V; Pitta, MGDR; Rates, SMK; Vaudry, D1
Hamzehloei, L; Rajaei, Z; Rezvani, ME1
Jalali-Nadoushan, M; Roghani, M1
Frau, L; Morelli, M; Simola, N1
Bolondi, C; Cantelli-Forti, G; Hrelia, P; Morroni, F; Sita, G; Tarozzi, A; Zolezzi Moraga, JM1
Dixit, TS; Elased, KM; Lucot, JB; Sharma, AN1
He, Q; Li, R; Liang, T; Xu, L; Zheng, N1
Dong, F; Ji, FQ; Li, WS; Sun, HM; Wu, B; Xue, H; Yan, JH; Yang, S; Zhou, DS1
Bohner, LO; Costa, AP; De Lima, TC; Lino-de-Oliveira, C; Santos, EC; Silva, CF; Vieira, C1
Ciucci, MR; Russell, JA; Schaser, AJ1
Cui, C; Hu, L; Li, Y; Sun, L1
Raju, AB; Suresh, P1
Akram, MN; Chrétien, F; Despars, G; Domenget, C; Gherardi, R; Honnorat, J; Jurdic, P; Nataf, S; Ressnikoff, D; Touret, M; Uhlrich, J; Virgone-Carlotta, A1
Aguiar, JC; Guimarães, FS; Lisboa, SF; Magesto, AC; Resstel, LB1
Bao, X; Tai, W; Wang, X; Ye, X; Zhang, D; Zhao, B1
Döbrössy, MD; Nikkhah, G; Pauly, MC; Piroth, T; Schackel, S1
Aebischer, P; Bensadoun, JC; Coune, PG; Schneider, BL1
Erbas, O; Oltulu, F; Taskiran, D1
Britto, LR; Café-Mendes, CC; Hernandes, MS; Lima, LS; Munhoz, CD; Santos, GD; Scavone, C1
Grauer, SM; Hodgson, R; Hyde, LA1
Kinney, JW; Landers, MR; van Breukelen, F1
Akseki, HS; Eliküçük, B; Erbaş, O; Taşkıran, D1
Bao, XQ; Kong, LB; Kong, XC; Sun, H; Wu, LY; Zhang, D1
Abdu-Aguye, I; Hussaini, IM; Magaji, MG; Magaji, RA; Mohammed, M; Musa, AM1
Gong, X; Liang, X; Liu, L; Wang, X; Zhang, W1
Hammond, MD; Li, J; Mancini, NS; McCullough, LD; Venna, VR1
Kilic, FS; Kulluk, D; Musmul, A1
Björklund, A; Carta, M; Devoto, P; Rogers, JT; Shin, E1
Farhan, M; Haleem, DJ1
Büchele, F; Döbrössy, M; Hackl, C; Jiang, W; Nikkhah, G; Papazoglou, A1
Chen, G; Feng, J; Feng, W; Huang, Z; Niu, J; Shi, L; Wang, Y; Ye, C; Zhu, G1
Banerjee, M; Mohanakumar, KP; Nthenge-Ngumbau, DN; Tripathy, D; Verma, P1
Capozzo, A; Mattei, C; Mazzone, P; Scarnati, E; Vitale, F1
Bähr, M; Koch, JC; Lingor, P; Saal, KA; Szegő, ÉM; Tatenhorst, L; Tönges, L1
Brosnan, RJ; Mayhew, PD; Smith, A; Soares, JH1
Campbell, JC; Chen, N; De La Cruz, P; Jeyamohan, SB; Pilitsis, JG; Shin, D1
Han, B; Jin, HJ; Song, MY; Wang, T; Zhao, H1
Liu, TD; Yang, HD; Yang, Z1
Cantelli-Forti, G; Hrelia, P; Morroni, F; Sita, G; Tarozzi, A1
Jiang, L; Long, K; Lu, F; Qu, J; Schaeffel, F; Stell, WK; Ying, H; Zheng, Y; Zhou, X1
Li, A; Zhang, F2
Auburger, G; Bez, F; Brehm, N; Carlsson, T; Cenci, MA; Gispert, S; Kern, B1
Boll, MC; Campos-Arroyo, HD; Martínez-Lazcano, JC; Montes, S; Pérez-Neri, I; Pérez-Severiano, F; Ríos, C; Rodríguez-Páez, L; Sánchez-Mendoza, MA1
Jeon, SR; Kim, YH; Shin, ES; Yoon, HH1
Ba, XH1
Gordon, R; Kaptsov, V; Makarova, E; Podolski, I; Sengpiel, F; Vorobyov, V1
Abe, H; Arimori, K; Ikeda, T; Ishida, Y; Koganemaru, G; Yasuda, K1
Chen, L; Guo, Y; Han, LN; Li, LB; Liu, J; Sun, YN; Wang, Y; Zhang, L; Zhang, QJ; Zhang, YM1
Bertolino, G; de Araujo, JE; Giorgetto, C; Kitabatake, TT; Silva, EC1
Collantes, M; Delgado, M; Ecay, M; Gago, B; Iglesias, E; Juri, C; Marín, C; Molinet-Dronda, F; Obeso, JA; Peñuelas, I; Prieto, E; Quiroga-Varela, A1
Chen, JF; Huang, F; Qu, J; Xiong, W; Yan, T; Ying, H; Zheng, F; Zhou, X1
Galeotti, N; Ghelardini, C; Peroni, D; Quattrone, A; Sanna, MD1
Duan, SJ; Han, B; Lu, Y; Wang, LJ; Wang, SY; Wang, T; Zhu, Q1
Cheng, CY; Chiu, CH; Chou, TK; Huang, WS; Huang, YS; Li, IH; Liao, MH; Ma, KH; Shiue, CY; Weng, SJ; Wu, SC1
Cui, G; Hua, F; Shen, X; Shi, H; Wang, X; Yang, X; Zhang, S; Zhang, W; Zhang, Z; Zhao, H; Zu, J1
Duan, SS; Ha, S; Li, ZA; Shi, YL; Wang, XL; Zhang, XS1
Baluchnejadmojarad, T; Kiasalari, Z; Roghani, M1
Deng, Y; Lu, J; Ma, H; Qing, H; Sun, F1
Galabov, AS; Nikolova, I; Stoyanova, A1
Avanzini, MA; Blandini, F; Bonizzi, A; Cerri, S; Fuzzati-Armentero, MT; Ghezzi, C; Greco, R; Levandis, G; Maccario, R; Mangione, AS1
Du, GH; Du, LD; He, GR; Mu, X; Yuan, X1
Czarnecka, A; Konieczny, J; Lenda, T; Lorenc-Koci, E1
Chae, MR; Han, DH; Kang, SJ; Kim, CY; Kim, JJ; Lee, SW; Park, JK; Sung, HH1
Hiratochi, M; Ijiro, T; Kaidoh, K; Oana, F; Suzuki, T; Tsuchioka, A; Yamauchi, Y1
Farhan, M; Haleem, DJ; Ikram, H; Kanwal, S1
Arai, Y; Hisamitsu, T; Nakagawasai, O; Nakajima, T; Nemoto, W; Takahashi, K; Tan-No, K1
Brauer, AF; Ciucci, MR; Kelm-Nelson, CA1
Canto-de-Souza, A; Furuya-da-Cunha, EM; Souza, RR1
Alipour Heidari, M; Dargahi, T; Faraji, A; Fraidouni, N; Haghdoost-Yazdi, H; Mahmudi, M; Piri, H1
Fisher, R; Jackson, MJ; Jenner, P; Lees, AJ; Lincoln, L; Neumeyer, J; Rose, S; Sromek, AW1
Carey, RJ; Carrera, MP; Dias, FRC; Oliveira, LR; Santos, BG; Silva, JLL1
Barkholt, P; Fabricius, K; Hansen, HH; Jelsing, J; Knudsen, LB; Mikkelsen, JD; Pyke, C; Vrang, N1
Bez, F; Cenci, MA; Francardo, V1
Armida, M; Calamandrei, G; Pezzola, A; Popoli, P; Potenza, RL; Tartaglione, AM1
Blobaum, AL; Bubser, M; Conn, PJ; Daniels, JS; Engers, DW; Hopkins, CR; Javitch, JA; Jones, CK; Lin, X; Lindsley, CW; Loch, MT; Niswender, CM; Rodriguez, AL; Thompson Gray, A1
Aliaghaei, A; Gardaneh, M; Gharib, E; Maghsoudi, N; Salehinejad, P1
Aguiar, LMV; Barros, AS; Bezerra, MM; Cavalcanti, JU; Crispim, RYG; Cristino Filho, G; de Barros Viana, GS; de Vasconcelos, SMM; Lemos, JC; Macêdo, DS; Pinheiro, TFM; Souza, RB1
Azevedo, BN; Calice da Silva, C; da Costa, JC; Machado, DC; Martins, LAM; Zimmer, ER1
Chen, W; Fu, X; Huang, L; Kong, X; Luo, Y; Pu, Z; Tang, H; Wei, S; Xing, H1
Bahri, MA; Becker, G; Garraux, G; Hustadt, F; Lemaire, C; Luxen, A; Michel, A; Plenevaux, A1
Abuirmeileh, A; Harkavyi, A; Kingsbury, A; Lever, R; Whitton, PS1
Ankoudinova, I; Bankiewicz, K; Federoff, HJ; Forsayeth, J; Guschin, D; Hadaczek, P; Horovitz, K; Johnston, LC; Maguire-Zeiss, K; Su, X1
Domanska-Janik, K; Gielecki, J; Gornicka-Pawlak, E; Janowski, M; Kozlowska, H; Lukomska, B1
Sengpiel, F; Vorobyov, V1
Glavan, G1
Bardin, L; Barret-Grévoz, C; Depoortère, R; Newman-Tancredi, A1
Alberts, JL; Ghosh, D; Johnson, MD; Mera, TO; Rothe, D; Vitek, J; Xu, W; Zhang, J1
Jadavji, NM; Metz, GA1
Daniels, WM; Di Chiara, G; Morelli, M; Schallert, T; Simola, N1
Bi, J; Gu, S; Huang, H; Wen, T; Yao, Y1
Dechant, G; Hainzer, M; Köllensperger, M; Nikkhah, G; Pallua, A; Poewe, W; Puschban, Z; Reindl, M; Stefanova, N; Wenning, GK1
Aebischer, P; Bensadoun, JC; Dusonchet, J; Schneider, BL1
Ding-Fang, C; Guo-Hua, W; Hong-Min, T; Hua-Wei, L; Jun, M; Jun-Peng, G; Shan, S; Wen-Wei, L; Xiang-Yu, W; Ya-Ling, H; Yan-Hong, T; Yi, F; Yue, F; Yun-Ke, Y1
Da Cunha, C; Ferro, MM; Gregório, ML; Silveira, JL; Vital, MA; Wietzikoski, EC1
Brus, H; Brus, R; Drab, J; Jochem, J; Körossy, E; Kostrzewa, RM; Noras, L; Nowak, P; Szkilnik, R1
Niimi, K; Takahashi, E1
Hirabayashi, H; Ishizaka, S; Matsuda, R; Nakase, H; Nishimura, F; Nonaka, J; Ouji, Y; Sakaki, T; Toriumi, H; Yamada, S; Yoshikawa, M1
Büchele, F; Döbrössy, M; Jiang, W; Nikkhah, G; Papazoglou, A1
Azar, MR; Geyer, MA; Gold, L; Marston, HM; Martin, FD; Meltzer, LT; Moore, CL; Serpa, KA; Shahid, M; Wong, EH; Young, JW1
Björklund, A; Carlsson, T; Carta, M; Kirik, D; Muñoz, A; Tronci, E1
Ballion, B; Chetrit, J; Frenois, F; Gonon, F; Murer, MG; Zold, CL1
Beal, MF; Bogdanov, M; Burke, RE; Geghman, K; Jackson-Lewis, V; Li, C; Li, Y; Liu, W; Oo, TF; Przedborski, S; Tang, Y; Wang, L; Zhou, C1
Jia, J; Li, B; Liu, L; Pan, Y; Sun, Z; Wang, H; Wang, X; Yu, F; Zhang, L1
Bilici, N; Gören, B; Korfali, E; Mimbay, Z; Oğul, E; Zarifoğlu, M1
De Jonghe, BC; Horn, CC; Matyas, K; Norgren, R1
Ali, U; Chen, L; Gui, ZH; Hui, YP; Li, Q; Liu, J; Wang, Y; Wu, ZH; Zhang, QJ1
Martens, GJ; Van Loo, KM; Van Schijndel, JE; Van Zweeden, M1
Amalric, M; Flor, PJ; Greco, B; Lopez, S; van der Putten, H1
Achaval, M; Anselmo-Franci, JA; Bagatini, PB; de David, C; Delattre, AM; Ferraz, AC; Iagher, F; Kiss, A; Marroni, NA; Rigon, P; Szawka, RE; Xavier, LL1
Johansson, SM; Modo, MM; Vernon, AC1
Ahmed, MR; Bychkov, E; Gurevich, EV1
Nakagawasai, O; Niijima, F; Onogi, H; Sato, A; Tadano, T; Tan-No, K1
Mei, J; Niu, C1
Cheng, B; Hu, W; Li, S; Liu, T; Tian, Y1
Ai, Y; Bradley, LH; Fuqua, J; Gash, DM; Gerhardt, GA; Glass, JD; Grondin, R; He, X; Huettl, P; Kelps, KA; Littrell, OM; Pomerleau, F; Richardson, A; Turchan-Cholewo, J; Zhang, Z1
Bordet, R; Destée, A; Duhamel, A; Kreisler, A; Vanbesien-Mailliot, C1
Björklund, A; Draxler, P; Grealish, S; Mattsson, B1
Baluchnejadmojarad, T; Jalali-Nadoushan, MR; Khalili, M; Kiasalari, Z; Niknam, A; Roghani, M1
Kunselman, AR; Lieu, CA; Manyam, BV; Subramanian, T; Venkiteswaran, K1
de Carvalho, CR; Duarte, FS; Horst, H; Moreira, EL; Pizzolatti, MG; Prediger, RD; Rial, D; Ribeiro-do-Valle, RM1
Chan, JS; de Jong, TR; Olivier, B; Oosting, RS; Snoeren, EM; Waldinger, MD1
Al-Amin, H; Atweh, S; Jabbur, S; Saadé, N; Sarkis, R2
Anvret, A; Belin, AC; Duester, G; Galter, D; Lindqvist, E; Ogren, SO; Pernold, K; Westerlund, M1
Cumming, P; Kjaerby, C; Knudsen, GM; Palner, M1
Bähr, M; Garrido, M; Kügler, S; Taschenberger, G; Tereshchenko, Y; Zhevtsova, Z1
Cao, G; Chen, J; Chu, CT; Gao, Y; Greenamyre, JT; Hastings, T; Hu, X; Signore, A; Weng, Z; Zhang, L; Zhu, J1
Krauss, JK; Lütjens, G; Schwabe, K1
Hashimoto, T; Himeno, E; Kira, J; LaFerla, FM; Ma, L; Miyoshi, K; Motomura, K; Nakamura, N; Ohyagi, Y; Sakae, N; Soejima, N; Tabira, T; Yamasaki, R1
Chen, JJ; Chen, LH; Chiang, PT; Hsieh, TH; Lee, HY1
Domanska-Janik, K; Drela, K; Gornicka-Pawlak, EB; Habich, A; Jablonska, A; Janowski, M; Kozlowska, H; Lukomska, B; Sypecka, J1
Af Bjerkén, S; Gerhardt, GA; Lundblad, M; Nevalainen, N; Strömberg, I1
Faraji, A; Fraidouni, N; Hadibeygi, E; Haghdoost-Yazdi, H; Movahedi, M; Vaezi, F1
Andreatini, R; Chioca, LR; Correia, D; Pereira, M; Pizzolatti, MG; Santos, AR; Siba, IP; Vital, MA1
Filli, L; Schwab, ME; Weinmann, O; Zörner, B1
Ali, U; Chen, L; Gui, ZH; Liu, J; Wang, T; Wang, Y1
Evinger, C; Horn, KG; Hui, C; Kaminer, J; Powers, AS1
Chan, YS; Chen, LW; Chu, JM; Yung, KK1
Carlsson, T; Döbrössy, M; García, J; Nikkhah, G; Winkler, C1
Geng, XC; Yin, LL; Zhu, XZ1
Anvret, A; Belin, AC; Duester, G; Felder, MR; Galter, D; Gellhaar, S; Lindqvist, E; Lundströmer, K; Pernold, K; Ran, C; Westerlund, M1
Bilge, U; Erol, K1
Champagne, DL; Daskalakis, NP; de Kloet, ER; Oitzl, MS; Schächinger, H1
Afzal, M; Ahmed, S; Ahmed, Z; Anwar, F; Ashraf, MS; Gupta, G; Kazmi, I; Khusroo, MJ; Mujeeb, M; Nazeer, K; Rahman, M; Saleem, S1
Döbrössy, MD; García, J; Kaindlstorfer, C; Nikkhah, G; Wenning, GK; Winkler, C1
Faraji, A; Fraidouni, N; Haghdoost-Yazdi, H; Jahanihashemi, H; Sarookhani, M1
Cao, Y; Ge, Y; Hu, X; Yin, P; Zhou, X1
Gewirtz, JC; Radke, AK1
Dabole, B; Dawe, A; De Waard, M; Dimo, T; Djomeni Dzeufiet, PD; Ngo Bum, E; Okomolo Moto, FC; Sidiki, N; Sotoing Taïwe, G; Talla, E; Temkou Ngoupaye, G1
Ahmad, A; Ishrat, T; Islam, F; Khan, A; Khan, MM; Safhi, MM; Shrivastava, P; Tabassum, R; Vaibhav, K1
Chen, Y; Liu, BF; Liu, X; Xu, X; Zhang, G1
Dunnett, SB; Garcia, J; Klein, A; Krause, M; Maciaczyk, J; Nikkhah, G; Papazoglou, A; Pruszak, J; Rath, A1
Bretsztajn, L; Eardley, I; Mohee, A1
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Al Mashhadi, S; Beattie, CE; Lyon, AN; McDearmid, JR; McGown, A; Panagiotaki, N; Ramesh, TM; Redhead, N; Shaw, PJ; Tong, H1
Kanda, T; Miyauchi, N; Yamada, K1
Bezard, E; Björklund, A; Carta, M; Li, Q; Pioli, EY; Porras, G; Tronci, E1
Britto, LR; Chaves-Kirsten, GP; Ferreira, AF; Pires, RS; Real, CC; Torrão, AS1
Caudle, WM; Cohen, AD; Miller, GW; Schallert, T; Tillerson, JL; Zigmond, MJ1
Matsumura, M1
Cools, AR; Ellenbroek, BA1
Bauer, P; Cattaneo, E; Dittmann, A; Haas, SJ; Knoblich, R; Mix, E; Peters, S; Petrov, S; Rolfs, A; Strauss, U; Weinelt, S; Wree, A1
Cannizzaro, C; Jackson, MJ; Jenner, P; Maratos, EC; Pearce, RK1
Gonzalez, CL; Vergara-Aragon, P; Whishaw, IQ1
Gerlach, M; Halliday, GM; Heinemann, T; Henderson, JM; Watson, S1
Chung, JH; Joo, WS; Kim, CJ; Kim, YJ; Kim, YS; Lee, HJ; Lee, HS; Leem, K; Lim, S; Park, HJ; Seo, JC; Son, YS; Yin, CS1
Garland, T; Rhodes, JS1
Cohen, AD; Schallert, T; Smith, AD; Tillerson, JL; Zigmond, MJ1
van den Buuse, M2
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Hannesson, DK; Howland, JG; Phillips, AG1
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Chen, SD; Liang, L; Lu, GQ; Wang, XJ; Xu, JY; Ye, M; Zhang, YH1
Han, ZT; Liu, J; Liu, S; Pang, JX; Wang, TH; Wei, P; Wu, QY; Zhou, HL1
Ho, YJ; Hsu, CC; Hsu, WY; Lei, YP; Tseng, T; Wang, CF; Wang, WF1
Chen, XY; Li, J; Qi, WQ; Shen, SH1
Amorosi, A; De Fazio, P; De Fazio, S; De Sarro, G; Donato, G; Perrotta, I; Russo, E1
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Martens, GJ; van Loo, KM1
Michaelides, M; Piyis, YK; Thanos, PK; Volkow, ND; Wang, GJ1
Carlson, NE; Gunzler, SA; Meshul, CK; Nutt, JG; Shakil, S1
Fu, Q; Lv, JJ; Zhang, H1
Debetto, P; Giusti, P; Guidolin, D; Negro, A; Peroni, D; Recchia, A; Rota, D; Skaper, SD1
Canteras, NS; Da Cunha, C; Ferro, MM; Hipólide, D; Martinez, GR; Tufik, S; Vital, MA; Wietzikoski, EC1
Kääriäinen, TM; Kekki, H; Lecklin, A; Lehtonen, S; Männistö, PT; Nenonen, T; Ossola, B; Piltonen, M; Raasmaja, A1
An, L; Li, YF; Liu, XM; Yu, NJ; Yuan, L; Zhang, YZ; Zhao, N1
Agam, G; Belmaker, RH; Bersudsky, Y; Kozlovsky, N; Shaldubina, A; Woodgett, JR1
Cheng, Y; Li, YG; Wei, AY1
Glassman, HN; Glassman, RB1
Havemann, U1
Gómez, A; Pesenti, L; Troncoso San Martín, E1
Carvey, P; Goetz, CG; Klawans, HL2
Lapierre, YD; Rastogi, RB; Rastogi, SK; Singhal, RL1
Curtin, J; Fields, J; Koller, W1
Andrews, JS; Biggins, JA; Candy, JM; Edwardson, JA; Keith, AB; Sahgal, A; Turner, JD; Wright, C1
Offermeier, J; van Rooyen, JM1
Baker, HJ; Cox, N; Lorden, JF; McKeon, TW; Walkley, SU1
Alanen, E; Pohto, P; Sundén-Kuronen, B1
Fink, H; Morgenstern, R; Oelssner, W1
Dijkstra, H; Stoof, JC; Thieme, RE1
Burnham, WM; King, GA1
Kogan, MJ; Mulè, SJ; Verebey, K1
Antolik, EK; Faison, EP; Yarbrough, GG1
Borison, R; Diamond, BI; Reyes, MG1
Canonico, PL; Clementi, G; Fiore, L; Gessa, GL; Nicoletti, F; Patti, F; Scapagnini, U; Tigano, G1
Johnels, B; Steg, G1
Oelssner, W1
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Diamond, BI; Gordon, JH1
Cools, AR; Ellenbroek, BA; Geyer, MA1
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Donaldson, D; Ferreira, M; Jackson-Lewis, V; Jiang, H; Levivier, M; Przedborski, S; Togasaki, DM1
Barnéoud, P; Blanchard, JC; Boireau, A; Dubédat, P; Mazadier, M; Miquet, JM; Parmentier, S1
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Borlongan, CV; Cahill, DW; Randall, TS; Sanberg, PR1
Crabbe, J; Gancher, S; Garland, A; Lea, E; Woodward, W1
Bohn, MC; Breakefield, XO; Cunningham, LA; Short, MP1
Cools, AR; Hermus, AR; Sweep, CG; van de Langerijt, AG; van den Berg, WB; van Lent, PL1
LeDuc, PA; Mittleman, G; Whishaw, IQ1
Overstreet, DH; Pucilowski, O1
Alpert, C; Belmaker, RH; Bersudsky, Y; Kofman, O; Vinnitsky, I1
Arnaldo, CM; Gonzalez, LP1
Glenthøj, B; Hemmingsen, R; Holm, S; Laursen, H; Mogensen, J1
Hasegawa, S; Matsunaga, T; Morita, M; Takeda, N1
Geyer, MA; Swerdlow, NR1
Bohn, MC; Breakefield, XO; Collier, TJ; Frim, DM; Lin, Q; Yoshimoto, Y1
Abarbanel, J; Belmaker, RH; Fleischmann, A; Prolov, K1
Corbett, R; Kafka, SH1
Starr, MS1
Conrad, JA; Kondoh, T; Low, WC; Pundt, LL1
Blaney, TJ; Chandonait, SE; Emerich, DF; Lindner, MD; Mullins, TD; Plone, MA; Sherman, SS; Stott, JA; Winn, SR1
Gancher, S; Mayer, A; Youngman, S1
Lipska, BK; Weinberger, DR1
Sugiura, K; Yokoyama, M; Yoshimura, H1
Guerra, MJ; Labandeira-García, JL; Rozas, G1
Araujo, DM; Hilt, DC; Jiao, S; Lapchak, PA; Sheng, J1
Schroeder, SR; Stodgell, CJ; Tessel, RE; Van Keuren, KR1
Loupe, PS; Schroeder, SR; Stodgell, CJ; Tessel, RE1
Brotchie, JM; Crossman, AR; Duty, S; Henry, B1
Turgut, M1
Agid, Y; Dziewczapolski, G; García, MC; Gershanik, O; Menalled, LB; Murer, MG; Raisman-Vozari, R1
Cohen, LK; Leff, SE; Mandel, RJ; Rendahl, KG; Snyder, RO; Spratt, SK1
Kang, UJ; Leff, SE; Mandel, RJ; Rendahl, KG; Spratt, SK1
Areso, MP; García-Vallejo, P; Giralt, MT; Gómez, FM; Sainz, B1
Guerra, MJ; Labandeira-García, JL; López-Martín, E; Rozas, G1
al-Amin, HA; Lipska, BK; Weinberger, DR1
Chopin, P; Colpaert, F; Marien, M; Martel, J1
Itakura, T; Nakai, K; Nakao, N; Ogura, M1
Chang, JW; Kang, UJ; Wachtel, SR; Young, D1
Becker, A; Bernstein, HG; Bogerts, B; Grecksch, G; Höllt, V1
Berkuzki, T; Grünblatt, E; Mandel, S; Youdim, MB1
Colin, P; Corti, O; Hamon, M; Hanoun, N; Mallet, J; Sánchez-Capelo, A1
Hashimoto, T; Izawa, Y; Kato, T; Moriizumi, T; Yokoyama, H1
Ahmad, B; Darmani, NA; Zhao, W1
Adachi, K; Cools, AR; Hasegawa, M; Hirose, N; Ikeda, H; Koshikawa, N; Sato, M1
Mandel, RJ1
Heijnen, CJ1
Aoi, M; Date, I; Ohmoto, T; Tomita, S1
Davidson, BL; During, MJ; Freese, A; Janson, CG; Leone, P; McPhee, SW1
Stoessl, AJ; Van Kampen, JM1
Andreatini, R; Beijamini, V; Joca, SR; Skalisz, LL; Vital, MA1
Humpel, C; Levivier, M; Poewe, W; Puschban, Z; Scherfler, C; Seppi, K; Stefanova, N; Waldner, R; Wenning, GK1
Cui, X; Li, XJ; Ma, XJ; Sun, AM; Wang, LN; Wang, ZF; Xue, YL; Zhong, DG; Zhu, K1
Boksa, P; Vaillancourt, C1
Dabbeni-Sala, F; Franceschini, D; Giusti, P; Skaper, SD1
Bell, KP; Choi, PK; Clarkson, ED; Esplen, JE; Freed, CR; Heidenreich, KA; Zawada, WM1
Caron, MG; Gainetdinov, RR; Hen, R; Jones, SR; Miller, GW; Oosting, RS; Zhuang, X1
Behzadi, G; Roghani, M1
Jellinger, K; Poewe, W; Puschban, Z; Scherfler, C; Seppi, K; Waldner, R; Wenning, GK1
Cui, X; Gao, J; Li, C; Li, X; Luo, Y; Sun, AM; Sun, R; Wang, L; Wang, Z; Xi, Z; Xue, Y; Zhou, D1
Allikmets, L; Matto, V; Pruus, K; Rudissaar, R; Skrebuhhova-Malmros, T1
Chen, RC; Chen, TH; Liou, HH; Tsai, MC; Tsai, YF1
Grünblatt, E; Mandel, S; Maor, G; Youdim, MB1
Beech, JS; Hodges, H; Stroemer, RP; Veizovic, T; Watson, WP1
Jacques, DB; Kopyov, O; Olds, ME1
Gordienko, DV; Krivobok, GK; Pankrat'ev, DV; Talalaenko, AN; Zinkovich, II1
Cohen, AD; Miller, GW; Philhower, J; Schallert, T; Tillerson, JL; Zigmond, MJ1
Baillet, C; Callizot, N; Guénet, JL; Poindron, P; Warter, JM1
Coenen, AM; Kuznetsova, GD; Midzianovskaia, IS; Spiridonov, AM; van Luijtelaar, EL1
Chen, MT; Hoffer, BJ; Janak, PH; Morales, M; Woodward, DJ1
Bankiewicz, KS; Cunningham, J; Harvey-White, J; Sánchez-Pernaute, R1
Shults, CW; Tsuboi, K1
Abe, K; Kashihara, K; Manabe, Y; Murakami, T1
Brotchie, JM; Crossman, AR; Silverdale, MA1
Li, Y; Robinson, TE; Samaha, AN1
Adams, MA; Brien, SE; Gofton, WT; Heaton, JP; Smallegange, C1
Lu, JQ; Stoessl, AJ1
Gerhardt, GA; Granholm, AC; Hoffer, BJ; Lintz, E; McGrath, J; Quintero, EM1
Fibiger, HC; Mason, ST; Sanberg, PR1
Fibiger, HC; Mason, ST1
Horsman, L; Pullar, IA; Tye, NC; Wright, FC1
Crossman, AR; Sambrook, MA1
Crossman, AR; Sambrook, MA; Slater, P1
Fibiger, HC; Lehmann, J; Sanberg, PR1
Anlezark, GM; Marsden, CD; Meldrum, BS1
Klawans, HL; Koller, WC; Nausieda, PA; Weiner, WJ1
Alpern, HP; Greer, CA1
Davis, KL; Hollister, LE; Simonton, S; Vento, AL1
Kenny, M; Leonard, BE1
Klawans, HL; Nausieda, PA; Weiner, WJ1
Flemenbaum, A1
Goetz, C; Klawans, HL; Nausieda, PA; Weiner, WJ1
Poirier, LJ1
David, J; Grewal, RS; Kaul, CL1
Beaton, JM; Bradley, RJ; Capra, N; Halsey, JH; Pegram, GV; Williams, RL1
Andén, NE; Johnels, B1
Ljungberg, T; Ungerstedt, U1
Klawans, HL; Margolin, DI1
Costall, B; Naylor, RJ1
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Brown, RE; Madge, GE; Schiller, HM1

Reviews

8 review(s) available for apomorphine and Disease Models, Animal

ArticleYear
Neural Stem/Progenitor Cell Transplantation in Parkinson's Rodent Animals: A Meta-Analysis and Systematic Review.
    Stem cells translational medicine, 2022, 04-29, Volume: 11, Issue:4

    Topics: Animals; Apomorphine; Disease Models, Animal; Humans; Parkinson Disease; Rodentia; Stem Cell Transplantation

2022
Oral r-(-)-11-o-valeryl-n-n-propylnoraporphine reverses motor deficits in mptp-treated marmosets.
    Movement disorders : official journal of the Movement Disorder Society, 2016, Volume: 31, Issue:9

    Topics: Animals; Apomorphine; Aporphines; Behavior, Animal; Callithrix; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Male; MPTP Poisoning; Valerates

2016
The evaluation of apomorphine for the treatment of erectile dysfunction.
    Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:11

    Topics: Administration, Sublingual; Animals; Apomorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Erectile Dysfunction; Humans; Male; Randomized Controlled Trials as Topic; Treatment Failure; United States

2012
[Subcutaneous apomorphine injection: rescue management of motor fluctuations associated with levodopa-therapy].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2013, Volume: 141, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Circadian Rhythm; Clinical Trials as Topic; Disease Models, Animal; Dopamine Agents; Humans; Injections, Subcutaneous; Levodopa; Parkinson Disease; Receptors, Dopamine; Salvage Therapy; Self Administration

2013
Experimental parkinsonism in primates.
    Stereotactic and functional neurosurgery, 2001, Volume: 77, Issue:1-4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Apomorphine; Basal Ganglia; Bicuculline; Cerebral Cortex; Disease Models, Animal; Dopamine; Dopamine Agonists; Electrocoagulation; GABA Antagonists; Globus Pallidus; Humans; Models, Neurological; MPTP Poisoning; Muscle Rigidity; Neurotoxins; Parkinsonian Disorders; Primates; Substance-Related Disorders; Substantia Nigra; Tegmentum Mesencephali; Thalamus

2001
Apomorphine susceptibility and animal models for psychopathology: genes and environment.
    Behavior genetics, 2002, Volume: 32, Issue:5

    Topics: Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Environment; Genetic Predisposition to Disease; Genetics, Behavioral; Rats; Rats, Inbred Strains; Schizophrenia; Species Specificity; Stereotyped Behavior

2002
Animal models of tardive dyskinesia: their use in the search for new treatment methods.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Age Factors; Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Carbidopa; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Combinations; Drug Interactions; Dyskinesia, Drug-Induced; Guinea Pigs; Haloperidol; Haplorhini; Humans; Levodopa; Lithium; Male; Parasympatholytics; Rats; Receptors, Dopamine; Stereotyped Behavior

1983
The role of dopamine in epilepsy.
    Synapse (New York, N.Y.), 1996, Volume: 22, Issue:2

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine; Epilepsy

1996

Other Studies

470 other study(ies) available for apomorphine and Disease Models, Animal

ArticleYear
1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction.
    Journal of medicinal chemistry, 2006, Aug-24, Volume: 49, Issue:17

    Topics: Animals; Benzamides; Binding Sites; Cell Line; Crystallography, X-Ray; Disease Models, Animal; Drug Evaluation, Preclinical; Erectile Dysfunction; Ferrets; Humans; Male; Models, Molecular; Molecular Structure; Oximes; Piperazines; Rats; Rats, Wistar; Receptors, Dopamine D4; Stereoisomerism; Structure-Activity Relationship

2006
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
    Physiological research, 2022, Aug-31, Volume: 71, Issue:4

    Topics: alpha-Synuclein; Animals; Antioxidants; Apomorphine; Curcumin; Disease Models, Animal; Glutathione Peroxidase; Malondialdehyde; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Oxidopamine; Parkinson Disease; Rats; Substantia Nigra

2022
5-(4-Hydroxy-3-dimethoxybenzylidene)-thiazolidinone improves motor functions and exerts antioxidant potential in hemiparkinsonian rats.
    Behavioural pharmacology, 2023, 02-01, Volume: 34, Issue:1

    Topics: Animals; Antioxidants; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Oxidopamine; Parkinson Disease; Rats; Substantia Nigra; Tyrosine 3-Monooxygenase

2023
Neurobehavioral Profiles of Six Genetically-based Rat Models of Schizophrenia- related Symptoms.
    Current neuropharmacology, 2023, Volume: 21, Issue:9

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine; Prepulse Inhibition; Rats; Rats, Brattleboro; Reflex, Startle; Schizophrenia

2023
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease.
    Journal of chemical neuroanatomy, 2023, Volume: 132

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Lacosamide; Male; Malondialdehyde; Mice; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Tumor Necrosis Factor-alpha

2023
Deep brain stimulation of the thalamic centromedian-parafascicular nucleus improves behavioural and neuronal traits in a rat model of Tourette.
    Behavioural brain research, 2020, 01-27, Volume: 378

    Topics: Animals; Apomorphine; Behavior, Animal; Deep Brain Stimulation; Disease Models, Animal; Dopamine Agonists; Electrocorticography; Intralaminar Thalamic Nuclei; Male; Neostriatum; Nucleus Accumbens; Prepulse Inhibition; Rats; Rats, Sprague-Dawley; Reflex, Startle; Sensorimotor Cortex; Theta Rhythm; Tourette Syndrome

2020
Nei-like 1 inhibition results in motor dysfunction and promotes inflammation in Parkinson's disease mice model.
    Biochemical and biophysical research communications, 2020, 01-01, Volume: 521, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Disease Models, Animal; DNA Glycosylases; Inflammation; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Oxidopamine; Parkinson Disease; Stereotaxic Techniques

2020
mGluR5 Allosteric Modulation Promotes Neurorecovery in a 6-OHDA-Toxicant Model of Parkinson's Disease.
    Molecular neurobiology, 2020, Volume: 57, Issue:3

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopaminergic Neurons; Male; Mice; Neurodegenerative Diseases; Oxidopamine; Parkinson Disease; Receptor, Metabotropic Glutamate 5

2020
Dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (Danio rerio) under circumstances of motivational conflict: Towards a screening test for anti-compulsive drug action.
    Behavioural brain research, 2020, 02-03, Volume: 379

    Topics: Animals; Apomorphine; Behavior, Animal; Citalopram; Conflict, Psychological; Disease Models, Animal; Dopamine Agonists; Feedback, Psychological; Motivation; Obsessive-Compulsive Disorder; Reward; Selective Serotonin Reuptake Inhibitors; Social Behavior; Zebrafish

2020
Antipsychotic-like profile of CIQ isomers in animal models of schizophrenia.
    Behavioural pharmacology, 2020, Volume: 31, Issue:6

    Topics: Animals; Antipsychotic Agents; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Male; Maze Learning; Mice; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Social Interaction; Stereoisomerism; Stereotyped Behavior

2020
L-linalool exerts a neuroprotective action on hemiparkinsonian rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2020, Volume: 393, Issue:6

    Topics: Acyclic Monoterpenes; Animals; Apomorphine; Brain; Disease Models, Animal; Dopamine; Lipid Peroxidation; Male; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar

2020
Pentadecapeptide BPC 157 counteracts L-NAME-induced catalepsy. BPC 157, L-NAME, L-arginine, NO-relation, in the suited rat acute and chronic models resembling 'positive-like' symptoms of schizophrenia.
    Behavioural brain research, 2021, 01-01, Volume: 396

    Topics: Amphetamine; Animals; Apomorphine; Arginine; Behavior, Animal; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Enzyme Inhibitors; Haloperidol; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Proteins; Rats; Rats, Wistar; Schizophrenia

2021
Engrafted primary type-2 astrocytes improve the recovery of the nigrostriatal pathway in a rat model of Parkinson's disease.
    Molecular and cellular biochemistry, 2021, Volume: 476, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Adrenergic Agents; Animals; Apomorphine; Astrocytes; Disease Models, Animal; Dopaminergic Neurons; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra

2021
Effect of Consecutive Alternating Administration of a Triple Combination of Anti-Enteroviral Compounds in Mice Infected with Coxsackievirus B3.
    Pathogens and disease, 2020, 11-23, Volume: 78, Issue:9

    Topics: Animals; Antiviral Agents; Apomorphine; Cell Line; Coxsackievirus Infections; Disease Models, Animal; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Enterovirus B, Human; Humans; Mice; Nitriles; Oxadiazoles; Oxazoles; Virus Replication

2020
Restraint-induced behavioral deficits are attenuated or impaired by pre- or post-injection of apomorphine: A context-based study.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Brain; Central Nervous System Stimulants; Disease Models, Animal; Eating; Elevated Plus Maze Test; Injections, Intravenous; Male; Motor Activity; Rats, Wistar; Restraint, Physical; Stress, Psychological; Time Factors

2020
Increased emissions of 50-kHz ultrasonic vocalizations in hemiparkinsonian rats repeatedly treated with dopaminomimetic drugs: A potential preclinical model for studying the affective properties of dopamine replacement therapy in Parkinson's disease.
    Progress in neuro-psychopharmacology & biological psychiatry, 2021, 06-08, Volume: 108

    Topics: Affect; Animals; Apomorphine; Desipramine; Disease Models, Animal; Dopamine Agents; Levodopa; Male; Parkinsonian Disorders; Pramipexole; Rats; Rats, Sprague-Dawley; Ultrasonic Waves; Vocalization, Animal

2021
The Effect of Levosimendan on Two Distinct Rodent Models of Parkinson's Disease.
    Current Alzheimer research, 2020, Volume: 17, Issue:11

    Topics: Animals; Apomorphine; Cardiotonic Agents; Disease Models, Animal; Dopamine; Dopamine Agents; Male; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Simendan; Substantia Nigra; Sympatholytics

2020
Cortical and Striatal Electroencephalograms and Apomorphine Effects in the FUS Mouse Model of Amyotrophic Lateral Sclerosis.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 81, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Animals; Apomorphine; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Electroencephalography; Male; Mice; Mice, Transgenic; Motor Neurons

2021
Protective effect of caffeine and/or taurine on the 6-hydroxydopamine-induced rat model of Parkinson's disease: Behavioral and neurochemical evidence.
    Restorative neurology and neuroscience, 2021, Volume: 39, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Caffeine; Corpus Striatum; Disease Models, Animal; Dopamine; Oxidopamine; Parkinson Disease; Rats; Taurine

2021
Antidepressant-Like Properties of Intrastriatal Botulinum Neurotoxin-A Injection in a Unilateral 6-OHDA Rat Model of Parkinson's Disease.
    Toxins, 2021, 07-20, Volume: 13, Issue:7

    Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Botulinum Toxins, Type A; Corpus Striatum; Disease Models, Animal; Injections; Male; Motor Activity; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Rats; Rats, Wistar

2021
Morphological dendritic spine changes of medium spiny neurons in the nucleus accumbens in 6-hydroxydopamine-lesioned rats treated with levodopa.
    Neuroscience research, 2017, Volume: 121

    Topics: Animals; Apomorphine; Dendritic Spines; Disease Models, Animal; Dopamine Agents; Levodopa; Male; Medial Forebrain Bundle; Neurons; Nucleus Accumbens; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Statistics, Nonparametric; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase

2017
Neuroprotective effect of epidermal growth factor in experimental acrylamide neuropathy: an electrophysiological approach.
    Journal of the peripheral nervous system : JPNS, 2017, Volume: 22, Issue:2

    Topics: Acrylamide; Action Potentials; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Electric Stimulation; Epidermal Growth Factor; Hand Strength; Male; Mice; Mice, Inbred C57BL; Neurologic Examination; Neuroprotective Agents; Penile Erection; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Time Factors

2017
Magnetic Resonance Imaging as a Noninvasive Method for Longitudinal Monitoring of Infusion Site Reactions Following Administration of a Novel Apomorphine Formulation.
    Toxicologic pathology, 2017, Volume: 45, Issue:4

    Topics: Animals; Antiparkinson Agents; Apomorphine; Biomarkers; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Injection Site Reaction; Injections, Subcutaneous; Magnetic Resonance Imaging; Male; Parkinson Disease; Swine

2017
Altered somatosensory cortex neuronal activity in a rat model of Parkinson's disease and levodopa-induced dyskinesias.
    Experimental neurology, 2017, Volume: 294

    Topics: Action Potentials; Animals; Antiparkinson Agents; Apomorphine; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Glutamate Decarboxylase; Levodopa; Motor Cortex; Nerve Tissue Proteins; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, GABA; RNA, Messenger; Sympatholytics; Tandem Mass Spectrometry

2017
Apomorphine Therapy for Neuronal Insulin Resistance in a Mouse Model of Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 58, Issue:4

    Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Exploratory Behavior; Gene Expression Regulation; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Insulysin; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Phosphorylation; Presenilin-1

2017
Antipsychotic-like activity of scopoletin and rutin against the positive symptoms of schizophrenia in mouse models.
    Experimental animals, 2017, Oct-30, Volume: 66, Issue:4

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Male; Methantheline; Mice, Inbred ICR; Morinda; Phytotherapy; Quaternary Ammonium Compounds; Rutin; Schizophrenia; Schizophrenic Psychology; Scopoletin; Stair Climbing; Stereotyped Behavior

2017
An ethanolic extract of Desmodium adscendens exhibits antipsychotic-like activity in mice.
    Journal of basic and clinical physiology and pharmacology, 2017, Sep-26, Volume: 28, Issue:5

    Topics: Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Disease Models, Animal; Ethanol; Fabaceae; Female; Haloperidol; Mice; Mice, Inbred ICR; Motor Activity; Phytotherapy; Plant Extracts

2017
Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis.
    BMC complementary and alternative medicine, 2017, Aug-07, Volume: 17, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Asteraceae; Behavior, Animal; Catalepsy; Chlorpromazine; Disease Models, Animal; Haloperidol; Herb-Drug Interactions; Hypnotics and Sedatives; Mice, Inbred BALB C; Mice, Inbred ICR; Motor Activity; Phytotherapy; Plant Extracts; Psychotic Disorders

2017
Interaction of Brain-Derived Neurotrophic Factor Val66Met genotype and history of stress in regulation of prepulse inhibition in mice.
    Schizophrenia research, 2018, Volume: 198

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Apomorphine; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Genotype; Humans; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Polymorphism, Genetic; Prepulse Inhibition; Stress, Psychological; Valine

2018
Morin Pretreatment Attenuates Schizophrenia-Like Behaviors in Experimental Animal Models.
    Drug research, 2018, Volume: 68, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonoids; Immobility Response, Tonic; Ketamine; Locomotion; Male; Mice; Rotarod Performance Test; Stereotyped Behavior

2018
Objectively measuring effects of electro-acupuncture in parkinsonian rhesus monkeys.
    Brain research, 2018, Jan-01, Volume: 1678

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acupuncture Therapy; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Electroacupuncture; Female; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Motor Activity; Motor Cortex; Parkinson Disease; Parkinson Disease, Secondary

2018
Alpha Lipoamide Ameliorates Motor Deficits and Mitochondrial Dynamics in the Parkinson's Disease Model Induced by 6-Hydroxydopamine.
    Neurotoxicity research, 2018, Volume: 33, Issue:4

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Apomorphine; Cell Death; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Exploratory Behavior; Forelimb; Male; Mesencephalon; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Motor Activity; Motor Disorders; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Sympatholytics; Thioctic Acid

2018
Effect of varenicline on behavioral deficits in a rat model of Parkinson's disease induced by unilateral 6-hydroxydopamine lesion of substantia nigra.
    Behavioural pharmacology, 2018, Volume: 29, Issue:4

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Motor Activity; Nicotinic Agonists; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Substantia Nigra; Varenicline

2018
Differential effects of dopaminergic drugs on spontaneous motor activity in the common marmoset following pretreatment with a bilateral brain infusion of 6-hydroxydopamine.
    Behavioural pharmacology, 2017, Volume: 28, Issue:8

    Topics: Animals; Apomorphine; Area Under Curve; Callithrix; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopaminergic Neurons; Dose-Response Relationship, Drug; Immunohistochemistry; Levodopa; Male; Methamphetamine; Motor Activity; Oxidopamine; Parkinsonian Disorders; Substantia Nigra; Tyrosine 3-Monooxygenase

2017
A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission.
    Translational psychiatry, 2017, 11-30, Volume: 7, Issue:11

    Topics: Abnormalities, Multiple; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Chromosome Deletion; Chromosomes, Human, Pair 1; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Excitatory Amino Acid Antagonists; Megalencephaly; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Phencyclidine; Phenotype; Prepulse Inhibition; Quinpirole; Receptors, Dopamine; Schizophrenia; Ventral Tegmental Area

2017
A small dose of apomorphine counteracts the deleterious effects of middle cerebral artery occlusion in different models.
    Archives italiennes de biologie, 2017, Sep-01, Volume: 155, Issue:3

    Topics: Animals; Apomorphine; Brain; Disease Models, Animal; Dopamine Agonists; Infarction, Middle Cerebral Artery; Male; Mice; Muscle Strength; Neurons; Neuroprotective Agents; Rats; Rats, Wistar

2017
Involvement of adenosine triphosphate-sensitive potassium channels in the neuroprotective activity of hydrogen sulfide in the 6-hydroxydopamine-induced animal model of Parkinson's disease.
    Behavioural pharmacology, 2018, Volume: 29, Issue:4

    Topics: Adenosine Triphosphate; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Hydrogen Sulfide; KATP Channels; Male; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; Potassium Channels; Rats; Rats, Wistar; Substantia Nigra

2018
Changes in Male Rat Sexual Behavior and Brain Activity Revealed by Functional Magnetic Resonance Imaging in Response to Chronic Mild Stress.
    The journal of sexual medicine, 2018, Volume: 15, Issue:2

    Topics: Animals; Apomorphine; Brain; Depression; Disease Models, Animal; Erectile Dysfunction; Female; Magnetic Resonance Imaging; Male; Penile Erection; Rats; Rats, Wistar; Sexual Behavior

2018
Pirouetting pigs: A large non-primate animal model based on unilateral 6-hydroxydopamine lesioning of the nigrostriatal pathway.
    Brain research bulletin, 2018, Volume: 139

    Topics: Amphetamine; Animals; Apomorphine; Biophysics; Central Nervous System Stimulants; Corpus Striatum; Deep Brain Stimulation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Functional Laterality; Magnetic Resonance Imaging; Neural Pathways; Oxidopamine; Parkinsonian Disorders; Substantia Nigra; Swine; Swine, Miniature; Sympatholytics; Tyrosine 3-Monooxygenase

2018
Analysis of respiratory movements in a mouse model of late Parkinson's disease submitted to stress.
    Respiratory physiology & neurobiology, 2018, Volume: 251

    Topics: Animals; Apomorphine; Cineradiography; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Locomotion; Male; Mice; Mice, Inbred C57BL; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Respiration; Stress, Physiological; Sympatholytics

2018
Electroacupuncture Alleviates Motor Symptoms and Up-Regulates Vesicular Glutamatergic Transporter 1 Expression in the Subthalamic Nucleus in a Unilateral 6-Hydroxydopamine-Lesioned Hemi-Parkinsonian Rat Model.
    Neuroscience bulletin, 2018, Volume: 34, Issue:3

    Topics: Adrenergic Agents; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Electroacupuncture; Functional Laterality; Male; Medial Forebrain Bundle; Motor Activity; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Subthalamic Nucleus; Tyrosine 3-Monooxygenase; Up-Regulation; Vesicular Glutamate Transport Protein 1

2018
Identification of metabolite biomarkers for L-DOPA-induced dyskinesia in a rat model of Parkinson's disease by metabolomic technology.
    Behavioural brain research, 2018, 07-16, Volume: 347

    Topics: Animals; Antiparkinson Agents; Apomorphine; Arachidonic Acids; Biomarkers; Cannabinoid Receptor Agonists; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dyskinesia, Drug-Induced; Endocannabinoids; Glycerides; Levodopa; Male; Metabolome; Metabolomics; Motor Activity; Oxidopamine; Parkinsonian Disorders; Polyunsaturated Alkamides; Rats, Sprague-Dawley

2018
Evaluation of the antiparkinsonism and neuroprotective effects of hydrogen sulfide in acute 6-hydroxydopamine-induced animal model of Parkinson's disease: behavioral, histological and biochemical studies.
    Neurological research, 2018, Volume: 40, Issue:7

    Topics: Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Glutathione Peroxidase; Hydrogen Sulfide; Male; Malondialdehyde; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Postural Balance; Rats; Rats, Wistar; Rotarod Performance Test; Superoxide Dismutase; Sympatholytics

2018
Feeding-produced subchronic high plasma levels of uric acid improve behavioral dysfunction in 6-hydroxydopamine-induced mouse model of Parkinson's disease.
    Behavioural pharmacology, 2019, Volume: 30, Issue:1

    Topics: Adrenergic Agents; Animals; Apomorphine; Disease Models, Animal; Hyperuricemia; Male; Mental Disorders; Mice; Mice, Inbred ICR; Motor Activity; Oxidopamine; Oxonic Acid; Parkinson Disease, Secondary; Rotarod Performance Test; Tyrosine 3-Monooxygenase; Uric Acid

2019
Dopamine D1 Receptors Contribute Critically to the Apomorphine-Induced Inhibition of Form-Deprivation Myopia in Mice.
    Investigative ophthalmology & visual science, 2018, 05-01, Volume: 59, Issue:6

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Electroretinography; Mice; Mice, Inbred C57BL; Mice, Knockout; Myopia; Receptors, Dopamine D1; Retina; Sensory Deprivation

2018
Protective and therapeutic activity of honokiol in reversing motor deficits and neuronal degeneration in the mouse model of Parkinson's disease.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:4

    Topics: Animals; Apomorphine; Biphenyl Compounds; Corpus Striatum; Disease Models, Animal; Lignans; Male; Mice; Microinjections; Motor Activity; Neuroprotective Agents; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Oxidopamine; Parkinson Disease, Secondary; Postural Balance; Substantia Nigra; Tyrosine 3-Monooxygenase

2018
Behavioral and neurochemical responses derived from dopaminergic intrastriatal grafts in hemiparkinsonian rats engaged in a novel motor task.
    Journal of neuroscience methods, 2018, 09-01, Volume: 307

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Cell Differentiation; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Functional Laterality; LIM-Homeodomain Proteins; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Microdialysis; Oxidopamine; Parkinson Disease, Secondary; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase

2018
Involvement of prelimbic 5-HT
    Neurological research, 2018, Volume: 40, Issue:10

    Topics: Animals; Anxiety; Apomorphine; Desipramine; Disease Models, Animal; Dopamine Agents; Enzyme Inhibitors; Exploratory Behavior; Functional Laterality; Male; Maze Learning; Oxidopamine; Parkinsonian Disorders; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Agents; Sympatholytics

2018
The Protective Role of Brain CYP2J in Parkinson's Disease Models.
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: alpha-Synuclein; Animals; Apomorphine; Brain; Cell Line, Tumor; Chromatin Immunoprecipitation; Cytochrome P-450 Enzyme System; Disease Models, Animal; Dopaminergic Neurons; Humans; Lipopolysaccharides; Male; Myeloid Differentiation Factor 88; NF-E2-Related Factor 2; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Signal Transduction; Toll-Like Receptor 4

2018
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
    Journal of neuroinflammation, 2018, Aug-29, Volume: 15, Issue:1

    Topics: Acetophenones; Animals; Apomorphine; Cell Line, Transformed; Corpus Striatum; Disease Models, Animal; Dopamine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; Nerve Degeneration; Nod2 Signaling Adaptor Protein; Oxidopamine; Parkinson Disease, Secondary; Reactive Oxygen Species

2018
Vitamin D protects dopaminergic neurons against neuroinflammation and oxidative stress in hemiparkinsonian rats.
    Journal of neuroinflammation, 2018, Aug-31, Volume: 15, Issue:1

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Encephalitis; Exploratory Behavior; Lipid Peroxidation; Male; Oxidative Stress; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Stereotyped Behavior; Swimming; Sympatholytics; Tyrosine 3-Monooxygenase; Vitamin D

2018
State-dependent effects of the D
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:3

    Topics: Animals; Apomorphine; Aripiprazole; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopaminergic Neurons; Electroencephalography; Haloperidol; Male; Methylazoxymethanol Acetate; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Ventral Tegmental Area

2019
Dopamine D2 receptors in the basolateral amygdala modulate erectile function in a rat model of nonorganic erectile dysfunction.
    Andrologia, 2019, Volume: 51, Issue:1

    Topics: Animals; Apomorphine; Basolateral Nuclear Complex; Disease Models, Animal; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Erectile Dysfunction; Male; Penile Erection; Rats; Rats, Wistar; Receptors, Dopamine D2; Sexual Behavior, Animal; Stress, Psychological

2019
Attenuation of glutamatergic and nitrergic system contributes to the antidepressant-like effect induced by capsazepine in the forced swimming test.
    Behavioural pharmacology, 2019, Volume: 30, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Apomorphine; Arginine; Capsaicin; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Inhibitors; Exploratory Behavior; Glutamic Acid; Male; Microinjections; Nitric Oxide; Nitroprusside; Rats; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Swimming

2019
Behavioral tests predicting striatal dopamine level in a rat hemi-Parkinson's disease model.
    Neurochemistry international, 2019, Volume: 122

    Topics: Animals; Apomorphine; Behavior Rating Scale; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Male; Motor Activity; Nerve Degeneration; Parkinson Disease; Rats, Wistar; Substantia Nigra

2019
Rhodiola rosea root extract has antipsychotic-like effects in rodent models of sensorimotor gating.
    Journal of ethnopharmacology, 2019, May-10, Volume: 235

    Topics: Animals; Antipsychotic Agents; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Male; Medicine, Traditional; Mice; Mice, Inbred C57BL; Plant Extracts; Plant Roots; Prepulse Inhibition; Rats; Rats, Wistar; Rhodiola; Sensory Gating

2019
Loss of Midbrain Dopamine Neurons and Altered Apomorphine EEG Effects in the 5xFAD Mouse Model of Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 70, Issue:1

    Topics: Alzheimer Disease; Animals; Apomorphine; Brain; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Electroencephalography; Male; Mesencephalon; Mice; Mice, Transgenic

2019
PT-31, a putative α2-adrenoceptor agonist, is effective in schizophrenia cognitive symptoms in mice.
    Behavioural pharmacology, 2019, Volume: 30, Issue:7

    Topics: Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Cognition; Disease Models, Animal; Dopamine Agonists; Imidazolidines; Male; Memory; Memory Disorders; Memory, Long-Term; Mice; Mice, Inbred Strains; Rats; Rats, Wistar; Receptors, Adrenergic; Schizophrenia; Schizophrenic Psychology

2019
Effects of carvacrol and physical exercise on motor and memory impairments associated with Parkinson's disease.
    Arquivos de neuro-psiquiatria, 2019, 07-29, Volume: 77, Issue:7

    Topics: Animals; Apomorphine; Cymenes; Disease Models, Animal; Male; Memory Disorders; Motor Activity; Oxidative Stress; Parkinson Disease; Physical Conditioning, Animal; Rats; Rats, Wistar

2019
Alpha-lipoic acid protects against 6-hydroxydopamine-induced neurotoxicity in a rat model of hemi-parkinsonism.
    Brain research, 2013, Apr-10, Volume: 1505

    Topics: Adrenergic Agents; Animals; Apomorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Malondialdehyde; Neurons; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rotation; Substantia Nigra; Thioctic Acid

2013
Performance of movement in hemiparkinsonian rats influences the modifications induced by dopamine agonists in striatal efferent dynorphinergic neurons.
    Experimental neurology, 2013, Volume: 247

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dynorphins; Early Growth Response Protein 1; Enkephalins; Functional Laterality; Gene Expression Regulation; Male; Motor Neurons; Movement; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; RNA, Messenger

2013
Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease.
    Neurotoxicology, 2013, Volume: 36

    Topics: Actinin; Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Caspase 3; Disease Models, Animal; DNA Fragmentation; Dopamine Agonists; Glutathione; Glutathione Reductase; Glutathione Transferase; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rotarod Performance Test; Rotation; Sulfoxides; Tyrosine 3-Monooxygenase

2013
Antipsychotic-like effect of GLP-1 agonist liraglutide but not DPP-IV inhibitor sitagliptin in mouse model for psychosis.
    Physiology & behavior, 2013, Apr-10, Volume: 114-115

    Topics: Animals; Antipsychotic Agents; Apomorphine; Disease Models, Animal; Dopamine Agonists; Glucagon-Like Peptide 1; Liraglutide; Male; Mice; Psychotic Disorders; Pyrazines; Sitagliptin Phosphate; Statistics, Nonparametric; Triazoles

2013
Puerarin attenuates neuronal degeneration and blocks oxidative stress to elicit a neuroprotective effect on substantia nigra injury in 6-OHDA-lesioned rats.
    Brain research, 2013, Jun-23, Volume: 1517

    Topics: Adrenergic Agents; Animals; Apomorphine; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Isoflavones; Male; Malondialdehyde; Microtubule-Associated Proteins; Motor Activity; NAD(P)H Dehydrogenase (Quinone); Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Oxidoreductases; Protein Deglycase DJ-1; Rats; Rats, Wistar; Substantia Nigra; Time Factors

2013
Conditioned medium from human amniotic epithelial cells may induce the differentiation of human umbilical cord blood mesenchymal stem cells into dopaminergic neuron-like cells.
    Journal of neuroscience research, 2013, Volume: 91, Issue:7

    Topics: Amnion; Analysis of Variance; Animals; Apomorphine; Brain-Derived Neurotrophic Factor; Cell Differentiation; Culture Media, Conditioned; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fetal Blood; Fetus; Flow Cytometry; Homeodomain Proteins; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Nuclear Receptor Subfamily 4, Group A, Member 2; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptor, trkA; Receptor, trkB; RNA, Messenger; Stereotyped Behavior; Transcription Factors; Tyrosine 3-Monooxygenase

2013
A proposal for refining the forced swim test in Swiss mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Aug-01, Volume: 45

    Topics: Animals; Antidepressive Agents; Apomorphine; Caffeine; Central Nervous System Stimulants; Desipramine; Disease Models, Animal; Fluoxetine; Imipramine; Immobility Response, Tonic; Male; Mice; Principal Component Analysis; Swimming; Time Factors

2013
Exercise-induced rescue of tongue function without striatal dopamine sparing in a rat neurotoxin model of Parkinson disease.
    Behavioural brain research, 2013, Sep-01, Volume: 252

    Topics: Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Electric Stimulation; Forelimb; Functional Laterality; Hypoglossal Nerve; Male; Movement; Muscle Strength; Neurotoxins; Oxidopamine; Parkinson Disease; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Time Factors; Tongue; Tongue Diseases; Tyrosine 3-Monooxygenase

2013
Mesoaccumbens dopamine signaling alteration underlies behavioral transition from tolerance to sensitization to morphine rewarding properties during morphine withdrawal.
    Brain structure & function, 2014, Volume: 219, Issue:5

    Topics: Action Potentials; Analgesics, Opioid; Animals; Apomorphine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopaminergic Neurons; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Signal Transduction; Substance Withdrawal Syndrome; Time Factors; Ventral Tegmental Area

2014
Antidopaminergic effects of leucine and genistein on shizophrenic rat models.
    Neurosciences (Riyadh, Saudi Arabia), 2013, Volume: 18, Issue:3

    Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopaminergic Neurons; Genistein; Leucine; Motor Activity; Protein Kinase Inhibitors; Rats; Rats, Wistar; Schizophrenia; Stereotyped Behavior

2013
Mapping and kinetics of microglia/neuron cell-to-cell contacts in the 6-OHDA murine model of Parkinson's disease.
    Glia, 2013, Volume: 61, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Adrenergic Agents; Animals; Antigens, Differentiation; Apomorphine; Cell Communication; Cell Count; Disease Models, Animal; Dopamine Agonists; Female; Green Fluorescent Proteins; Imaging, Three-Dimensional; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Microscopy, Confocal; Neurons; Oxidopamine; Parkinson Disease; Receptors, Interleukin-8A; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2013
Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats.
    Neuropharmacology, 2013, Volume: 75

    Topics: Animals; Anxiety; Apomorphine; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; GABA-A Receptor Antagonists; Male; Maze Learning; Nitric Oxide Synthase; Oxadiazoles; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1

2013
Inhibition of Src tyrosine kinase activity by squamosamide derivative FLZ attenuates neuroinflammation in both in vivo and in vitro Parkinson's disease models.
    Neuropharmacology, 2013, Volume: 75

    Topics: Animals; Apomorphine; Benzeneacetamides; Cell Line; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Encephalitis; Enzyme Activation; Enzyme Activators; Exploratory Behavior; Lipopolysaccharides; Male; Mice; Motor Activity; Parkinson Disease; Phenols; Rats; Rats, Wistar; src-Family Kinases

2013
Donor age dependent graft development and recovery in a rat model of Huntington's disease: histological and behavioral analysis.
    Behavioural brain research, 2013, Nov-01, Volume: 256

    Topics: Age Factors; Animals; Apomorphine; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Female; Fetal Tissue Transplantation; Globus Pallidus; Huntington Disease; Motor Activity; Neurons; Quinolinic Acid; Rats, Sprague-Dawley; Recovery of Function

2013
Rab1A over-expression prevents Golgi apparatus fragmentation and partially corrects motor deficits in an alpha-synuclein based rat model of Parkinson's disease.
    Journal of Parkinson's disease, 2011, Volume: 1, Issue:4

    Topics: alpha-Synuclein; Animals; Apomorphine; Disease Models, Animal; Dopaminergic Neurons; Exploratory Behavior; Female; Forelimb; Genetic Vectors; Golgi Apparatus; Humans; Male; Mice; Mutation; Parkinson Disease; rab1 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2011
Suppression of exaggerated neuronal oscillations by oxytocin in a rat model of Parkinson's disease.
    General physiology and biophysics, 2013, Volume: 32, Issue:4

    Topics: Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Electroencephalography; Electrophysiological Phenomena; Male; Neostriatum; Neurons; Oxytocin; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotation

2013
Microglial cells are involved in the susceptibility of NADPH oxidase knockout mice to 6-hydroxy-dopamine-induced neurodegeneration.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Inflammation; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Minocycline; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; Nerve Degeneration; NF-kappa B; Oxidopamine; Parkinson Disease; Substantia Nigra; Tumor Necrosis Factor-alpha

2013
MitoPark mice, an animal model of Parkinson's disease, show enhanced prepulse inhibition of acoustic startle and no loss of gating in response to the adenosine A(2A) antagonist SCH 412348.
    Psychopharmacology, 2014, Volume: 231, Issue:7

    Topics: Adenosine A2 Receptor Antagonists; Aging; Animals; Apomorphine; Benzothiazoles; Disease Models, Animal; Dopamine Agonists; Male; Mice; Mice, Transgenic; Motor Activity; Parkinson Disease; Pramipexole; Prepulse Inhibition; Pyrimidines; Triazoles

2014
Forced exercise before or after induction of 6-OHDA-mediated nigrostriatal insult does not mitigate behavioral asymmetry in a hemiparkinsonian rat model.
    Brain research, 2014, Jan-16, Volume: 1543

    Topics: Adrenergic Agents; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Forelimb; Functional Laterality; Male; Oxidopamine; Parkinsonian Disorders; Physical Conditioning, Animal; Psychomotor Performance; Rats; Rats, Long-Evans; Stereotyped Behavior; Substantia Nigra

2014
Antipsychotic-like effect of trimetazidine in a rodent model.
    TheScientificWorldJournal, 2013, Volume: 2013

    Topics: Animals; Antipsychotic Agents; Apomorphine; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Humans; Male; Psychoses, Substance-Induced; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Treatment Outcome; Trimetazidine

2013
Squamosamide derivative FLZ protected dopaminergic neuron by activating Akt signaling pathway in 6-OHDA-induced in vivo and in vitro Parkinson's disease models.
    Brain research, 2014, Feb-14, Volume: 1547

    Topics: alpha-Synuclein; Animals; Apomorphine; Benzeneacetamides; Cell Death; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Male; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Phenols; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Repressor Proteins; Signal Transduction; Transcription Factors; Tyrosine 3-Monooxygenase

2014
Evaluation of the antipsychotic potential of aqueous fraction of Securinega virosa root bark extract in mice.
    Metabolic brain disease, 2014, Volume: 29, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Euphorbiaceae; Female; Grooming; Haloperidol; Male; Medicine, African Traditional; Methanol; Mice; Phytotherapy; Plant Bark; Plant Extracts; Plant Roots; Solvents; Stereotyped Behavior; Swimming; Water

2014
Relation between microPET imaging and rotational behavior in a parkinsonian rat model induced by medial forebrain bundle axotomy.
    Behavioural brain research, 2014, May-15, Volume: 265

    Topics: Animals; Apomorphine; Axotomy; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Functional Laterality; Male; Medial Forebrain Bundle; Parkinson Disease; Raclopride; Radionuclide Imaging; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2014
Chronic metformin treatment improves post-stroke angiogenesis and recovery after experimental stroke.
    The European journal of neuroscience, 2014, Volume: 39, Issue:12

    Topics: AMP-Activated Protein Kinases; Animals; Apomorphine; Brain; Disease Models, Animal; Dopamine Agonists; Infarction, Middle Cerebral Artery; Male; Metformin; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neovascularization, Pathologic; Neuroglia; Neuroprotective Agents; Physical Stimulation; Random Allocation; Recovery of Function; Stroke; Vascular Endothelial Growth Factor A

2014
Effects of dehydroepiandrosterone in amphetamine-induced schizophrenia models in mice.
    Neurosciences (Riyadh, Saudi Arabia), 2014, Volume: 19, Issue:2

    Topics: Adjuvants, Immunologic; Amphetamine; Animals; Apomorphine; Catalepsy; Central Nervous System Stimulants; Dehydroepiandrosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Locomotion; Mice; Schizophrenia; Statistics, Nonparametric; Time Factors

2014
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.
    Experimental neurology, 2014, Volume: 257

    Topics: Adrenergic Agents; Adrenergic Neurons; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Benzylamines; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Levodopa; Motor Activity; Nerve Degeneration; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Stereotyped Behavior

2014
Inhibition of apomorphine-induced behavioral sensitization in rats pretreated with fluoxetine.
    Behavioural pharmacology, 2015, Volume: 26, Issue:1-2

    Topics: Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Fluoxetine; Male; Motor Activity; Psychoses, Substance-Induced; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors

2015
Two-step grafting significantly enhances the survival of foetal dopaminergic transplants and induces graft-derived vascularisation in a 6-OHDA model of Parkinson's disease.
    Neurobiology of disease, 2014, Volume: 68

    Topics: Adrenergic Agents; Animals; Apomorphine; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Embryo, Mammalian; Female; Fetal Tissue Transplantation; Graft Survival; Green Fluorescent Proteins; Medial Forebrain Bundle; Nerve Fibers; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Transgenic; Time Factors

2014
PEGylated rhFGF-2 conveys long-term neuroprotection and improves neuronal function in a rat model of Parkinson's disease.
    Molecular neurobiology, 2015, Volume: 51, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Apoptosis; Astrocytes; Behavior, Animal; Biological Availability; Cell Survival; Disease Models, Animal; Dopaminergic Neurons; Fibroblast Growth Factor 2; Glial Fibrillary Acidic Protein; Male; Neostriatum; Neuroprotective Agents; Oxidopamine; Parkinson Disease; PC12 Cells; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Substantia Nigra; Tyrosine 3-Monooxygenase

2015
Regenerative therapy in experimental parkinsonism: mixed population of differentiated mouse embryonic stem cells, rather than magnetically sorted and enriched dopaminergic cells provide neuroprotection.
    CNS neuroscience & therapeutics, 2014, Volume: 20, Issue:8

    Topics: Adrenergic Agents; Amphetamine; Animals; Apomorphine; Brain; Cell Differentiation; Disease Models, Animal; Dopamine; Embryonic Stem Cells; Functional Laterality; Magnetics; Male; Medial Forebrain Bundle; Nerve Tissue Proteins; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation

2014
Continuous stimulation of the pedunculopontine tegmental nucleus at 40 Hz affects preparative and executive control in a delayed sensorimotor task and reduces rotational movements induced by apomorphine in the 6-OHDA parkinsonian rat.
    Behavioural brain research, 2014, Sep-01, Volume: 271

    Topics: Animals; Apomorphine; Deep Brain Stimulation; Disease Models, Animal; Dopamine Agonists; Executive Function; Male; Movement; Oxidopamine; Parkinsonian Disorders; Pedunculopontine Tegmental Nucleus; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Treatment Outcome

2014
Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.
    Journal of neuropathology and experimental neurology, 2014, Volume: 73, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic Agents; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Mice; Mice, Inbred C57BL; Motor Activity; Muscle Strength; Oxidopamine; Parkinson Disease; Protein Kinase Inhibitors; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2014
Rabbit model of chest wall rigidity induced by fentanyl and the effects of apomorphine.
    Respiratory physiology & neurobiology, 2014, Oct-01, Volume: 202

    Topics: Analgesics, Opioid; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Fentanyl; Lung Compliance; Muscle Rigidity; Rabbits; Thoracic Wall

2014
Place conditioning to apomorphine in rat models of Parkinson's disease: differences by dose and side-effect expression.
    Behavioural brain research, 2014, Dec-15, Volume: 275

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Functional Laterality; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Tyrosine 3-Monooxygenase

2014
A potential target for the treatment of Parkinson's disease: effect of lateral habenula lesions.
    Parkinsonism & related disorders, 2014, Volume: 20, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Habenula; Homovanillic Acid; Male; Medial Forebrain Bundle; Neurosurgery; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase

2014
[Effect of dopamine receptor agonist apomorphine on scopolamine induced memory deficits in mice].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2014, Volume: 30, Issue:3

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Male; Memory Disorders; Mice; Scopolamine

2014
Neuroprotection by 6-(methylsulfinyl)hexyl isothiocyanate in a 6-hydroxydopamine mouse model of Parkinson׳s disease.
    Brain research, 2014, Nov-17, Volume: 1589

    Topics: Animals; Apomorphine; Apoptosis; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Glutathione Reductase; Glutathione Transferase; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; Rotarod Performance Test; Rotation; Substantia Nigra; Tyrosine 3-Monooxygenase

2014
Effects of dopaminergic agents on progression of naturally occurring myopia in albino guinea pigs (Cavia porcellus).
    Investigative ophthalmology & visual science, 2014, Sep-30, Volume: 55, Issue:11

    Topics: Animals; Apomorphine; Benzazepines; Disease Models, Animal; Disease Progression; Dopamine Agonists; Dopamine Antagonists; Follow-Up Studies; Guinea Pigs; Myopia; Refraction, Ocular; Sulpiride; Treatment Outcome

2014
Dual regulating effects of gastrodin on extracellular dopamine concentration in rats models of Tourette's syndrome.
    The International journal of neuroscience, 2015, Volume: 125, Issue:10

    Topics: Animals; Apomorphine; Benzyl Alcohols; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Glucosides; Haloperidol; Homovanillic Acid; Male; Nitriles; Rats; Stereotyped Behavior; Tourette Syndrome; Up-Regulation

2015
A Genetic Mouse Model of Parkinson's Disease Shows Involuntary Movements and Increased Postsynaptic Sensitivity to Apomorphine.
    Molecular neurobiology, 2015, Volume: 52, Issue:3

    Topics: alpha-Synuclein; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Dyskinesias; Extracellular Signal-Regulated MAP Kinases; Humans; Locomotion; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mutation, Missense; Nerve Tissue Proteins; Parkinsonian Disorders; Phosphorylation; Point Mutation; Post-Synaptic Density; Prions; Promoter Regions, Genetic; Protein Processing, Post-Translational; Stereotyped Behavior; Substantia Nigra; Transgenes

2015
Sub-chronic copper pretreatment reduces oxidative damage in an experimental Huntington's disease model.
    Biological trace element research, 2014, Volume: 162, Issue:1-3

    Topics: Animals; Apomorphine; Copper; Disease Models, Animal; gamma-Aminobutyric Acid; Huntington Disease; Lipid Peroxidation; Male; Oxidative Stress; Quinolinic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase

2014
A rat model of striatonigral degeneration generated by simultaneous injection of 6-hydroxydopamine into the medial forebrain bundle and quinolinic acid into the striatum.
    Journal of Korean medical science, 2014, Volume: 29, Issue:11

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Glucose; Injections, Intraperitoneal; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Quinolinic Acid; Rats; Rats, Wistar; Striatonigral Degeneration; Touch

2014
Therapeutic effects of GM1 on Parkinson's disease in rats and its mechanism.
    The International journal of neuroscience, 2016, Volume: 126, Issue:2

    Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Female; G(M1) Ganglioside; Gene Expression Regulation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; RNA, Messenger; Stereotyped Behavior

2016
Neuroprotective effects of hydrated fullerene C60: cortical and hippocampal EEG interplay in an amyloid-infused rat model of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 45, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Apomorphine; Cerebral Cortex; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Fullerenes; Hippocampus; Male; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Wistar; Time Factors

2015
Dual ameliorative effects of Ningdong granule on dopamine in rat models of Tourette's syndrome.
    Scientific reports, 2015, Jan-16, Volume: 5

    Topics: Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Drugs, Chinese Herbal; Male; Medicine, Chinese Traditional; Nitriles; Rats; Rats, Wistar; Receptors, Dopamine D2; Tourette Syndrome; Up-Regulation

2015
Pramipexole reduces parkinsonian tremor induced by pilocarpine infusion in the rat striatum.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 131

    Topics: Animals; Antiparkinson Agents; Apomorphine; Benzothiazoles; Disease Models, Animal; Infusions, Intraventricular; Injections, Intraperitoneal; Male; Parkinsonian Disorders; Pilocarpine; Pramipexole; Rats; Rats, Sprague-Dawley; Ventral Striatum

2015
Activation of serotonin(2C) receptors in the lateral habenular nucleus increases the expression of depression-related behaviors in the hemiparkinsonian rat.
    Neuropharmacology, 2015, Volume: 93

    Topics: Action Potentials; Adrenergic Agents; Animals; Apomorphine; Depression; Disease Models, Animal; Dopamine Agonists; Exploratory Behavior; Food Preferences; Functional Laterality; Habenula; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin Agents; Substantia Nigra; Sucrose; Swimming

2015
Behavioural profile of Wistar rats with unilateral striatal lesion by quinolinic acid (animal model of Huntington disease) post-injection of apomorphine and exposure to static magnetic field.
    Experimental brain research, 2015, Volume: 233, Issue:5

    Topics: Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Functional Laterality; Huntington Disease; Magnetic Fields; Male; Motor Activity; Neurons; Quinolinic Acid; Rats; Rats, Wistar; Statistics as Topic

2015
Monoaminergic PET imaging and histopathological correlation in unilateral and bilateral 6-hydroxydopamine lesioned rat models of Parkinson's disease: a longitudinal in-vivo study.
    Neurobiology of disease, 2015, Volume: 77

    Topics: Adrenergic Agents; Animals; Apomorphine; Brain; Carbon Radioisotopes; Disease Models, Animal; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Functional Laterality; Longitudinal Studies; Magnetic Resonance Imaging; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tetrabenazine

2015
Daily Injection But Not Continuous Infusion of Apomorphine Inhibits Form-Deprivation Myopia in Mice.
    Investigative ophthalmology & visual science, 2015, Volume: 56, Issue:4

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Drug Administration Schedule; Infusions, Parenteral; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Myopia; Refraction, Ocular; Sensory Deprivation

2015
Spinal RyR2 pathway regulated by the RNA-binding protein HuD induces pain hypersensitivity in antiretroviral neuropathy.
    Experimental neurology, 2015, Volume: 267

    Topics: Analgesics, Non-Narcotic; Animals; Anti-HIV Agents; Apomorphine; Calcium Channel Blockers; Cell Line, Tumor; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; ELAV Proteins; ELAV-Like Protein 4; Exploratory Behavior; Gene Expression Regulation; Hyperalgesia; Male; Mice; Motor Activity; Neuroblastoma; Pain; Pain Threshold; Peripheral Nervous System Diseases; Ryanodine Receptor Calcium Release Channel; Spinal Cord; Zalcitabine

2015
Coadministration of hydroxysafflor yellow A with levodopa attenuates the dyskinesia.
    Physiology & behavior, 2015, Aug-01, Volume: 147

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Antiparkinson Agents; Apomorphine; Chalcone; Disease Models, Animal; Levodopa; Male; Motor Activity; Olfaction Disorders; Oxidopamine; Parkinson Disease; Quinones; Rats; Receptors, Dopamine D3; Time Factors

2015
PET Imaging of Serotonin Transporters With 4-[(18)F]-ADAM in a Parkinsonian Rat Model With Porcine Neural Xenografts.
    Cell transplantation, 2016, Volume: 25, Issue:2

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Male; Nerve Degeneration; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra; Swine; Transplantation, Heterologous

2016
Intranigral administration of substance P receptor antagonist attenuated levodopa-induced dyskinesia in a rat model of Parkinson's disease.
    Experimental neurology, 2015, Volume: 271

    Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Apomorphine; Disease Models, Animal; Dopamine; Dopamine Agonists; Drug Administration Schedule; Dyskinesia, Drug-Induced; Gene Expression Regulation; Indoles; Levodopa; Male; MAP Kinase Signaling System; Motor Activity; Neurokinin-1 Receptor Antagonists; Oxidopamine; Parkinson Disease; Piperidines; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors

2015
Tanshinone IIA protects dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity through miR-153/NF-E2-related factor 2/antioxidant response element signaling pathway.
    Neuroscience, 2015, Sep-10, Volume: 303

    Topics: Abietanes; Animals; Apomorphine; Apoptosis; Cell Survival; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Gene Expression Regulation; Glutathione; Humans; Male; Mice; Mice, Inbred C57BL; Neuroblastoma; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Oxidopamine; Reactive Oxygen Species; Signal Transduction; Stereotyped Behavior; Time Factors; Tyrosine 3-Monooxygenase

2015
Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease.
    Cellular and molecular neurobiology, 2016, Volume: 36, Issue:4

    Topics: Animals; Apomorphine; Catalase; Corpus Striatum; Disease Models, Animal; Ethanol; Glutathione; Hypericum; Male; Malondialdehyde; Mitogen-Activated Protein Kinases; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Plant Extracts; Rats, Wistar; Reaction Time; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase; Water

2016
Comparison between α-synuclein wild-type and A53T mutation in a progressive Parkinson's disease model.
    Biochemical and biophysical research communications, 2015, Sep-04, Volume: 464, Issue:4

    Topics: Age Factors; alpha-Synuclein; Amino Acid Substitution; Animals; Apomorphine; Brain; Disease Models, Animal; Dopaminergic Neurons; Immunohistochemistry; Male; Mutant Proteins; Mutation, Missense; Parkinsonian Disorders; Phosphorylation; Protein Aggregation, Pathological; Rats; Rats, Transgenic; Rats, Wistar; Recombinant Proteins; Torsion Abnormality

2015
Effect of consecutive alternating administration (CAA) of a triple anti-enteroviral combination on Coxsackievirus B1 neuroinfection in mice.
    Antiviral research, 2015, Volume: 121

    Topics: Animals; Antiviral Agents; Apomorphine; Brain; Central Nervous System Infections; Coxsackievirus Infections; Disease Models, Animal; Drug Resistance, Viral; Drug Therapy, Combination; Enterovirus B, Human; Guanidine; Mice, Inbred ICR; Microbial Sensitivity Tests; Oxadiazoles; Oxazoles; Survival Analysis; Treatment Outcome

2015
Intracarotid Infusion of Mesenchymal Stem Cells in an Animal Model of Parkinson's Disease, Focusing on Cell Distribution and Neuroprotective and Behavioral Effects.
    Stem cells translational medicine, 2015, Volume: 4, Issue:9

    Topics: Animals; Apomorphine; Behavior, Animal; Blood-Brain Barrier; Carotid Arteries; Cell Count; Cell Tracking; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Injections, Intra-Arterial; Injections, Intraventricular; Male; Mannitol; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neurons; Osmolar Concentration; Oxidopamine; Parkinson Disease, Secondary; Permeability; Rats; Rats, Wistar

2015
Antagonism of quercetin against tremor induced by unilateral striatal lesion of 6-OHDA in rats.
    Journal of Asian natural products research, 2016, Volume: 18, Issue:1

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Male; Molecular Structure; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Quercetin; Rats; Rats, Sprague-Dawley; Tremor

2016
The preferential nNOS inhibitor 7-nitroindazole and the non-selective one N(G)-nitro-L-arginine methyl ester administered alone or jointly with L-DOPA differentially affect motor behavior and monoamine metabolism in sham-operated and 6-OHDA-lesioned rats.
    Brain research, 2015, Nov-02, Volume: 1625

    Topics: Adrenergic Agents; Animals; Apomorphine; Biogenic Monoamines; Brain; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Indazoles; Levodopa; Locomotion; Male; Movement Disorders; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Oxidopamine; Rats; Rats, Wistar; Time Factors

2015
New Methodology for Investigating Ejaculation Dysfunction: Measuring Intraluminal Seminal Vesicle Pressure in Rats with a Telemetric Device.
    The journal of sexual medicine, 2015, Volume: 12, Issue:11

    Topics: Animals; Apomorphine; Disease Models, Animal; Ejaculation; Indoles; Male; Penis; Pressure; Rats; Rats, Sprague-Dawley; Seminal Vesicles; Sexual Behavior; Sulfonamides; Tamsulosin; Telemetry; Urological Agents

2015
Duration of drug action of dopamine D2 agonists in mice with 6-hydroxydopamine-induced lesions.
    Neuroreport, 2015, Dec-16, Volume: 26, Issue:18

    Topics: Animals; Antiparkinson Agents; Apomorphine; Azepines; Benzothiazoles; Cabergoline; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Ergolines; Indoles; Injections, Intraventricular; Male; Mice; Motor Activity; Oxidopamine; Parkinsonian Disorders; Pramipexole; Quinolines; Receptors, Dopamine D2; Tetrahydronaphthalenes; Thiophenes

2015
Apomorphine induced conditioned place preference and sensitization is greater in rats exposed to unpredictable chronic mild stress.
    Pakistan journal of pharmaceutical sciences, 2015, Volume: 28, Issue:6

    Topics: Animals; Apomorphine; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Chronic Disease; Conditioning, Psychological; Disease Models, Animal; Male; Motor Activity; Rats, Wistar; Reinforcement, Psychology; Stress, Psychological

2015
Alterations in behavioral responses to dopamine agonists in olfactory bulbectomized mice: relationship to changes in the striatal dopaminergic system.
    Psychopharmacology, 2016, Volume: 233, Issue:7

    Topics: Animals; Apomorphine; Corpus Striatum; Depression; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopaminergic Neurons; Imipramine; Male; Mice; Motor Activity; Nucleus Accumbens; Olfactory Bulb; Receptors, Dopamine D2; Smell; Tyrosine 3-Monooxygenase

2016
Vocal training, levodopa, and environment effects on ultrasonic vocalizations in a rat neurotoxin model of Parkinson disease.
    Behavioural brain research, 2016, 07-01, Volume: 307

    Topics: Animals; Antiparkinson Agents; Apomorphine; Carbidopa; Communication Disorders; Disease Models, Animal; Dopamine; Dopamine Agonists; Drug Combinations; Fourier Analysis; Levodopa; Male; Neurotoxins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Long-Evans; Stereotyped Behavior; Time Factors; Ultrasonics; Vocalization, Animal

2016
Rat exposure in mice with neuropathic pain induces fear and antinociception that is not reversed by 5-HT2C receptor activation in the dorsal periaqueductal gray.
    Behavioural brain research, 2016, 07-01, Volume: 307

    Topics: Analysis of Variance; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Exploratory Behavior; Fear; Male; Mice; Microinjections; Pain Measurement; Periaqueductal Gray; Pyrazines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2C; Sciatica; Serotonin Receptor Agonists

2016
Pretreatment with potassium channel blockers of 4-aminopyridine and tetraethylammonium attenuates behavioural symptoms of Parkinsonism induced by intrastriatal injection of 6-hydroxydopamine; the role of lipid peroxidation.
    Neurological research, 2016, Volume: 38, Issue:4

    Topics: 4-Aminopyridine; Adrenergic Agents; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Functional Laterality; Male; Mental Disorders; Motor Activity; Oxidopamine; Parkinsonian Disorders; Postural Balance; Potassium Channel Blockers; Rats; Rats, Wistar; Tetraethylammonium; Thiazolidinediones

2016
Post-trial dopaminergic modulation of conditioned catalepsy: A single apomorphine induced increase/decrease in dopaminergic activation immediately following a conditioned catalepsy response can reverse/enhance a haloperidol conditioned and sensitized cata
    Behavioural brain research, 2016, 09-15, Volume: 311

    Topics: Analysis of Variance; Animals; Apomorphine; Catalepsy; Conditioning, Classical; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Haloperidol; Male; Rats, Wistar

2016
Characterization of liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease.
    Brain research, 2016, 09-01, Volume: 1646

    Topics: Animals; Antiparkinson Agents; Apomorphine; Body Weight; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopaminergic Neurons; Glucagon-Like Peptide-1 Receptor; Liraglutide; Male; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase

2016
Dramatic differences in susceptibility to l-DOPA-induced dyskinesia between mice that are aged before or after a nigrostriatal dopamine lesion.
    Neurobiology of disease, 2016, Volume: 94

    Topics: Aging; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Levodopa; Mice, Inbred C57BL; Motor Activity; Oxidopamine; Parkinson Disease

2016
Aberrant self-grooming as early marker of motor dysfunction in a rat model of Huntington's disease.
    Behavioural brain research, 2016, 10-15, Volume: 313

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Grooming; Huntington Disease; Male; Quinolinic Acid; Rats; Rats, Sprague-Dawley

2016
Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 Heteromers.
    ACS chemical neuroscience, 2016, 09-21, Volume: 7, Issue:9

    Topics: Allosteric Regulation; Animals; Antiparkinson Agents; Antipsychotic Agents; Apomorphine; Brain; Catalepsy; Disease Models, Animal; Dopamine Agonists; Forelimb; Glutamic Acid; Haloperidol; HEK293 Cells; Humans; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Transfection

2016
Dopaminergic Induction of Umbilical Cord Mesenchymal Stem Cells by Conditioned Medium of Choroid Plexus Epithelial Cells Reduces Apomorphine-Induced Rotation in Parkinsonian Rats.
    Archives of Iranian medicine, 2016, Volume: 19, Issue:8

    Topics: Animals; Apomorphine; Cell Differentiation; Cells, Cultured; Choroid Plexus; Culture Media, Conditioned; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Epithelial Cells; Humans; Mesenchymal Stem Cells; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotation; Umbilical Cord

2016
Impact of the Chronic Omega-3 Fatty Acids Supplementation in Hemiparkinsonism Model Induced by 6-Hydroxydopamine in Rats.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 120, Issue:6

    Topics: Animals; Apomorphine; Biogenic Monoamines; Brain; Dietary Supplements; Disease Models, Animal; Fatty Acids, Omega-3; gamma-Aminobutyric Acid; Lipid Peroxidation; Male; Motor Activity; Nitrites; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar

2017
Dissociation between dopaminergic response and motor behavior following intrastriatal, but not intravenous, transplant of bone marrow mononuclear stem cells in a mouse model of Parkinson's disease.
    Behavioural brain research, 2017, 05-01, Volume: 324

    Topics: Administration, Intravenous; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Green Fluorescent Proteins; Male; Medial Forebrain Bundle; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred C57BL; Motor Activity; Oxidopamine; Parkinson Disease; Rotarod Performance Test; Substantia Nigra

2017
Oxoisoaporphine alkaloid derivative 8-1 reduces Aβ
    Neurochemistry international, 2017, Volume: 108

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Apomorphine; Benzodioxoles; Caenorhabditis elegans; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Oxidative Stress; Peptide Fragments; Phthalazines

2017
Comparative assessment of 6-[
    Journal of neurochemistry, 2017, Volume: 141, Issue:4

    Topics: Animals; Apomorphine; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Fluorine Radioisotopes; Image Processing, Computer-Assisted; Male; Neostriatum; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Stereotyped Behavior; Tyrosine

2017
The CRF-like peptide urocortin produces a long-lasting recovery in rats made hemiparkinsonian by 6-hydroxydopamine or lipopolysaccharide.
    Journal of the neurological sciences, 2008, Aug-15, Volume: 271, Issue:1-2

    Topics: Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Interactions; Hydroxydopamines; Lipopolysaccharides; Male; Microdialysis; Parkinson Disease, Secondary; Rats; Rats, Wistar; Recovery of Function; Time Factors; Tyrosine 3-Monooxygenase; Urocortins

2008
Human interleukin-10 gene transfer is protective in a rat model of Parkinson's disease.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2008, Volume: 16, Issue:8

    Topics: Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Dependovirus; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Forelimb; Gene Expression; Gene Expression Profiling; Genetic Therapy; Genetic Vectors; Humans; Hydroxydopamines; Immunohistochemistry; Interleukin-10; Male; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Substantia Nigra

2008
Structural and functional characteristic of a model for deep-seated lacunar infarct in rats.
    Journal of the neurological sciences, 2008, Oct-15, Volume: 273, Issue:1-2

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Infarction; Bromodeoxyuridine; Cell Proliferation; Discrimination Learning; Disease Models, Animal; Male; Motor Activity; Nerve Tissue Proteins; Neuropsychological Tests; Ouabain; Psychomotor Performance; Rats; Rats, Wistar; Statistics, Nonparametric; Time Factors

2008
Apomorphine-induced differences in cortical and striatal EEG and their glutamatergic mediation in 6-hydroxydopamine-treated rats.
    Experimental brain research, 2008, Volume: 191, Issue:3

    Topics: Alpha Rhythm; Animals; Apomorphine; Behavior, Animal; Beta Rhythm; Cerebral Cortex; Corpus Striatum; Delta Rhythm; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Osmotic Fragility; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Sympatholytics; Theta Rhythm

2008
Intermittent L-DOPA treatment differentially alters synaptotagmin 4 and 7 gene expression in the striatum of hemiparkinsonian rats.
    Brain research, 2008, Oct-21, Volume: 1236

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Female; Functional Laterality; Gene Expression; Levodopa; Motor Activity; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; RNA, Messenger; Synaptotagmins; Time Factors

2008
Apomorphine-induced emesis in dogs: differential sensitivity to established and novel dopamine D2/5-HT(1A) antipsychotic compounds.
    European journal of pharmacology, 2008, Nov-12, Volume: 597, Issue:1-3

    Topics: Animals; Antiemetics; Antipsychotic Agents; Apomorphine; Disease Models, Animal; Dogs; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Partial Agonism; Male; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Vomiting

2008
Objective quantification of arm rigidity in MPTP-treated primates.
    Journal of neuroscience methods, 2009, Feb-15, Volume: 177, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Arm; Deep Brain Stimulation; Disease Models, Animal; Electromyography; Electronic Data Processing; Female; Macaca mulatta; MPTP Poisoning; Muscle Rigidity; Muscle, Skeletal; Range of Motion, Articular

2009
Both pre- and post-lesion experiential therapy is beneficial in 6-hydroxydopamine dopamine-depleted female rats.
    Neuroscience, 2009, Jan-23, Volume: 158, Issue:2

    Topics: Animals; Apomorphine; Corticosterone; Disease Models, Animal; Dopamine; Environment; Exploratory Behavior; Female; Functional Laterality; Hippocampus; Locomotion; Microtubule-Associated Proteins; Motor Skills; Neurotoxicity Syndromes; Neurotoxins; Oxidopamine; Rats; Rats, Long-Evans; Tyrosine 3-Monooxygenase

2009
Priming of rotational behavior by a dopamine receptor agonist in Hemiparkinsonian rats: movement-dependent induction.
    Neuroscience, 2009, Feb-18, Volume: 158, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Functional Laterality; Male; Metyrapone; Movement; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Restraint, Physical; Rotarod Performance Test; Rotation; Time Factors

2009
Combined treatment of neurotrophin-3 gene and neural stem cells is ameliorative to behavior recovery of Parkinson's disease rat model.
    Brain research, 2009, Feb-27, Volume: 1257

    Topics: Animals; Apomorphine; Behavior, Animal; Cell Movement; Cells, Cultured; Disease Models, Animal; Dopamine; Genetic Therapy; Maze Learning; Medial Forebrain Bundle; Motor Activity; Nerve Degeneration; Neurogenesis; Neurons; Neurotrophin 3; Oxidopamine; Parkinsonian Disorders; Rats; Stem Cell Transplantation; Stem Cells; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2009
Striatal transplantation in a rodent model of multiple system atrophy: effects on L-Dopa response.
    Journal of neuroscience research, 2009, May-15, Volume: 87, Issue:7

    Topics: Analysis of Variance; Animals; Apomorphine; Brain; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Levodopa; Male; Motor Activity; Multiple System Atrophy; Random Allocation; Rats; Rats, Wistar; Transplantation, Homologous

2009
Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease.
    Neurobiology of disease, 2009, Volume: 35, Issue:1

    Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dependovirus; Disease Models, Animal; Dopamine; Female; Gene Expression; Green Fluorescent Proteins; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2009
New evidences for fractalkine/CX3CL1 involved in substantia nigral microglial activation and behavioral changes in a rat model of Parkinson's disease.
    Neurobiology of aging, 2011, Volume: 32, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Antibodies; Antiparkinson Agents; Apomorphine; Chemokine CX3CL1; Disease Models, Animal; DNA Nucleotidylexotransferase; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Levodopa; Male; Mental Disorders; Nerve Tissue Proteins; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reaction Time; Stereotyped Behavior; Substantia Nigra; Tyrosine 3-Monooxygenase

2011
Nicotine induces sensitization of turning behavior in 6-hydroxydopamine lesioned rats.
    Neurotoxicity research, 2009, Volume: 15, Issue:4

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electrochemistry; Functional Laterality; Ganglionic Stimulants; Male; Nicotine; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Time Factors

2009
Histaminergic activity in a rodent model of Parkinson's disease.
    Neurotoxicity research, 2009, Volume: 15, Issue:3

    Topics: Adrenergic Agents; Animals; Animals, Newborn; Apomorphine; Brain; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Exploratory Behavior; Histamine; Histamine Antagonists; Locomotion; Male; Mouth Abnormalities; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar

2009
Combination of modified SHIRPA and pharmacological approach uncovers neuronal alteration in senescence-accelerated mouse prone 6 (SAMP6) strain.
    Neuroscience letters, 2009, Jul-17, Volume: 458, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Exploratory Behavior; Hindlimb Suspension; Mice; Motor Activity; Neurons; Osteoporosis; Phenotype; Receptors, Dopamine

2009
Treatment of Parkinson's disease model mice with allogeneic embryonic stem cells: necessity of immunosuppressive treatment for sustained improvement.
    Neurological research, 2009, Volume: 31, Issue:3

    Topics: Animals; Apomorphine; Corpus Striatum; Cyclosporine; Disease Models, Animal; Embryonic Stem Cells; Immunosuppressive Agents; Lymphocyte Activation; Male; Mice; Mice, Inbred Strains; Motor Activity; Oxidopamine; Parkinson Disease; Stem Cell Transplantation; Time Factors; Transplantation, Homologous; Tyrosine 3-Monooxygenase

2009
Ketamine anaesthesia interferes with the quinolinic acid-induced lesion in a rat model of Huntington's disease.
    Journal of neuroscience methods, 2009, May-15, Volume: 179, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Antiparkinson Agents; Apomorphine; Brain; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Huntington Disease; Isoflurane; Ketamine; Neurons; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley

2009
Asenapine effects in animal models of psychosis and cognitive function.
    Psychopharmacology, 2009, Volume: 206, Issue:4

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Attention; Benzodiazepines; Cognition; Dibenzocycloheptenes; Disease Models, Animal; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Male; Olanzapine; Psychotic Disorders; Rats; Rats, Sprague-Dawley; Risperidone

2009
Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model.
    Experimental neurology, 2009, Volume: 219, Issue:1

    Topics: Animals; Apomorphine; Brain; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Levodopa; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists

2009
D2 receptor stimulation, but not D1, restores striatal equilibrium in a rat model of Parkinsonism.
    Neurobiology of disease, 2009, Volume: 35, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2

2009
Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease.
    Nature neuroscience, 2009, Volume: 12, Issue:7

    Topics: Age Factors; Animals; Antiparkinson Agents; Apomorphine; Brain; Chromosomes, Artificial, Bacterial; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Gene Transfer Techniques; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Mice; Mice, Transgenic; Movement Disorders; Mutation, Missense; Neurons; Nomifensine; Parkinson Disease; Protein Serine-Threonine Kinases

2009
Electro-acupuncture stimulation improves motor disorders in Parkinsonian rats.
    Behavioural brain research, 2009, Dec-14, Volume: 205, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Brain; Disease Models, Animal; Dopamine; Dyskinesias; Electroacupuncture; Enkephalins; Glutamate Decarboxylase; Male; Medial Forebrain Bundle; Motor Activity; Neurons; Parkinsonian Disorders; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Substance P; Tyrosine 3-Monooxygenase

2009
Investigation of neuroprotective effects of cyclooxygenase inhibitors in the 6-hydroxydopamine induced rat Parkinson model.
    Turkish neurosurgery, 2009, Volume: 19, Issue:3

    Topics: Amphetamines; Animals; Antiparkinson Agents; Apomorphine; Aspirin; Behavior, Animal; Cyclooxygenase Inhibitors; Disease Models, Animal; Female; Immunohistochemistry; Meloxicam; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Sympatholytics; Thiazines; Thiazoles

2009
Chemotherapy-induced kaolin intake is increased by lesion of the lateral parabrachial nucleus of the rat.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:5

    Topics: Animals; Antineoplastic Agents; Apomorphine; Behavior, Animal; Cisplatin; Disease Models, Animal; Eating; Emetics; Injections, Intraperitoneal; Kaolin; Male; Neurons, Afferent; Pica; Pons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Solitary Nucleus

2009
Noradrenergic lesion of the locus coeruleus increases apomorphine-induced circling behavior and the firing activity of substantia nigra pars reticulata neurons in a rat model of Parkinson's disease.
    Brain research, 2010, Jan-15, Volume: 1310

    Topics: Action Potentials; Adrenergic Agents; Animals; Apomorphine; Disease Models, Animal; Locus Coeruleus; Male; Movement; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Substantia Nigra; Tyrosine 3-Monooxygenase

2010
Gene expression profiling in brain regions of a rat model displaying schizophrenia-related features.
    Behavioural brain research, 2010, Mar-05, Volume: 207, Issue:2

    Topics: Animals; Apomorphine; Brain; Disease Models, Animal; Gene Expression Profiling; Kv Channel-Interacting Proteins; Male; Membrane Proteins; Microarray Analysis; Phenotype; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schizophrenia; Species Specificity

2010
Metabotropic glutamate 7 receptor subtype modulates motor symptoms in rodent models of Parkinson's disease.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:3

    Topics: Allosteric Regulation; Animals; Apomorphine; Benzhydryl Compounds; Catalepsy; Disease Models, Animal; Haloperidol; Male; Mice; Mice, Knockout; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Reaction Time; Receptors, Metabotropic Glutamate; Stereotyped Behavior

2010
Evaluation of chronic omega-3 fatty acids supplementation on behavioral and neurochemical alterations in 6-hydroxydopamine-lesion model of Parkinson's disease.
    Neuroscience research, 2010, Volume: 66, Issue:3

    Topics: Animals; Apomorphine; Brain; Cell Membrane; Disease Models, Animal; Dopamine; Dopamine Agonists; Fatty Acids, Omega-3; Lipid Peroxidation; Male; Motor Activity; Neurons; Oxidopamine; Parkinsonian Disorders; Random Allocation; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Treatment Outcome; Tyrosine 3-Monooxygenase

2010
Non-invasive evaluation of nigrostriatal neuropathology in a proteasome inhibitor rodent model of Parkinson's disease.
    BMC neuroscience, 2010, Jan-05, Volume: 11

    Topics: Acetylcysteine; alpha-Synuclein; Animals; Apomorphine; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dopamine; Dopamine Agonists; Iron; Magnetic Resonance Imaging; Male; Mesencephalon; Motor Activity; Neurons; Parkinsonian Disorders; Random Allocation; Rats; Rats, Sprague-Dawley; Substantia Nigra

2010
Sex differences in the activity of signalling pathways and expression of G-protein-coupled receptor kinases in the neonatal ventral hippocampal lesion model of schizophrenia.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:1

    Topics: Animals; Animals, Newborn; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; G-Protein-Coupled Receptor Kinases; HEK293 Cells; Hippocampus; Humans; Male; Mitogen-Activated Protein Kinase 3; Motor Activity; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Schizophrenia; Sex Characteristics; Signal Transduction

2011
Effect of non-selective dopaminergic receptor agonist on disrupted maternal behavior in olfactory bulbectomized mice.
    Behavioural brain research, 2010, Jul-11, Volume: 210, Issue:2

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Depression; Disease Models, Animal; Dopamine Agonists; Exploratory Behavior; Female; Food Preferences; Maternal Behavior; Mice; Olfactory Bulb; Sexual Behavior, Animal; Sucrose; Sweetening Agents

2010
Alterations of Hrd1 expression in various encephalic regional neurons in 6-OHDA model of Parkinson's disease.
    Neuroscience letters, 2010, Apr-26, Volume: 474, Issue:2

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Apomorphine; Brain; Disease Models, Animal; Male; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Sympatholytics; Ubiquitin-Protein Ligases; Up-Regulation

2010
Erectile function restoration after repair of excised cavernous nerves by autologous vein graft in rats.
    The journal of sexual medicine, 2010, Volume: 7, Issue:10

    Topics: Animals; Apomorphine; Disease Models, Animal; Erectile Dysfunction; Male; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Transplantation, Autologous; Veins

2010
Dopamine neuron stimulating actions of a GDNF propeptide.
    PloS one, 2010, Mar-18, Volume: 5, Issue:3

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Isoflurane; Male; Nerve Growth Factors; Neurons; Oligopeptides; Oxidopamine; Rats; Rats, Inbred F344; Signal Transduction; Substantia Nigra

2010
Differing short-term neuroprotective effects of the fibrates fenofibrate and bezafibrate in MPTP and 6-OHDA experimental models of Parkinson's disease.
    Behavioural pharmacology, 2010, Volume: 21, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Bezafibrate; Cell Count; Disease Models, Animal; Drug Interactions; Exploratory Behavior; Fenofibrate; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Statistics, Nonparametric; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2010
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease.
    The European journal of neuroscience, 2010, Volume: 31, Issue:12

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Female; Mice; Nerve Degeneration; Neural Pathways; Neuropsychological Tests; Oxidopamine; Parkinson Disease; Substantia Nigra; Sympatholytics

2010
Oral pelargonidin exerts dose-dependent neuroprotection in 6-hydroxydopamine rat model of hemi-parkinsonism.
    Brain research bulletin, 2010, Jul-30, Volume: 82, Issue:5-6

    Topics: Administration, Oral; Animals; Anthocyanins; Antiparkinson Agents; Apomorphine; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Lipid Peroxidation; Male; Mesencephalon; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Statistics, Nonparametric; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2010
A water extract of Mucuna pruriens provides long-term amelioration of parkinsonism with reduced risk for dyskinesias.
    Parkinsonism & related disorders, 2010, Volume: 16, Issue:7

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Female; Forelimb; Mucuna; Oxidopamine; Parkinsonian Disorders; Phytotherapy; Plant Extracts; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Rotation; Time Factors; Tyrosine 3-Monooxygenase; Vibrissae

2010
Central nervous system activity of the proanthocyanidin-rich fraction obtained from Croton celtidifolius in rats.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:8

    Topics: Anesthetics, Inhalation; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Apomorphine; Behavior, Animal; Central Nervous System Agents; Consciousness; Croton; Disease Models, Animal; Dose-Response Relationship, Drug; Ether; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Motor Activity; Pentylenetetrazole; Plant Bark; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Seizures; Stereotyped Behavior

2010
A new female rat animal model for hypoactive sexual desire disorder; behavioral and pharmacological evidence.
    The journal of sexual medicine, 2011, Volume: 8, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Female; Male; Paroxetine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Sexual Behavior, Animal; Sexual Dysfunctions, Psychological

2011
Chronic dizocilpine or apomorphine and development of neuropathy in two animal models II: effects on brain cytokines and neurotrophins.
    Experimental neurology, 2011, Volume: 228, Issue:1

    Topics: Animals; Apomorphine; Brain; Cytokines; Disease Models, Animal; Dizocilpine Maleate; Female; Interleukin-1beta; Nerve Growth Factors; Neuralgia; Rats; Rats, Sprague-Dawley

2011
Modeling Parkinson's disease genetics: altered function of the dopamine system in Adh4 knockout mice.
    Behavioural brain research, 2011, Mar-01, Volume: 217, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Dehydrogenase; Amphetamine; Analysis of Variance; Animals; Apomorphine; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Odorants; Parkinson Disease; Serotonin; Smell

2011
Chronic dizocilpine or apomorphine and development of neuropathy in two rat models I: behavioral effects and role of nucleus accumbens.
    Experimental neurology, 2011, Volume: 228, Issue:1

    Topics: Animals; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Female; Mononeuropathies; Motor Activity; Neuralgia; Nucleus Accumbens; Pain Measurement; Random Allocation; Rats; Rats, Sprague-Dawley

2011
Effects of unilateral 6-OHDA lesions on [3H]-N-propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat.
    Neurochemistry international, 2011, Volume: 58, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley

2011
Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons.
    Acta neuropathologica, 2011, Volume: 121, Issue:4

    Topics: alpha-Synuclein; Analysis of Variance; Animals; Apomorphine; Catalytic Domain; Cell Survival; Cysteine; Disease Models, Animal; Dopamine; Dopamine Agonists; Female; Gene Expression Regulation; Gliosis; Glutathione; Glutathione Reductase; Green Fluorescent Proteins; Movement; Nerve Degeneration; Rats; Rats, Wistar; RNA, Small Interfering; Sensation Disorders; Stereotyped Behavior; Substantia Nigra; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2011
Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jan-05, Volume: 31, Issue:1

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Animals; Apomorphine; Brain; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cytochromes; Disease Models, Animal; Dopamine; Enzyme Inhibitors; Female; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Indoles; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Middle Aged; Motor Activity; Neurodegenerative Diseases; Neuroprostanes; Oxidopamine; Parkinson Disease; Peroxiredoxins; Postmortem Changes; RNA, Small Interfering; Signal Transduction; Thioredoxins

2011
Lesions of the entopeduncular nucleus in rats prevent apomorphine-induced deficient sensorimotor gating.
    Behavioural brain research, 2011, Jul-07, Volume: 220, Issue:2

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Apomorphine; Conditioning, Operant; Disease Models, Animal; Disease Progression; Dopamine Agonists; Entopeduncular Nucleus; Gait Disorders, Neurologic; Inhibition, Psychological; Male; Maze Learning; Motor Activity; Rats; Rats, Sprague-Dawley; Reflex, Startle; Rotarod Performance Test

2011
Apomorphine treatment in Alzheimer mice promoting amyloid-β degradation.
    Annals of neurology, 2011, Volume: 69, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apomorphine; Blotting, Western; Brain; Cells, Cultured; Disease Models, Animal; Dopamine Agonists; Immunohistochemistry; Insulysin; Maze Learning; Memory, Short-Term; Mice; Mice, Transgenic; Neprilysin; Neurons; Oxidative Stress; Phosphorylation; Proteasome Endopeptidase Complex; Statistics, Nonparametric; tau Proteins

2011
Time-course gait analysis of hemiparkinsonian rats following 6-hydroxydopamine lesion.
    Behavioural brain research, 2011, Sep-12, Volume: 222, Issue:1

    Topics: Analysis of Variance; Animals; Apomorphine; Disease Models, Animal; Disease Progression; Functional Laterality; Gait Disorders, Neurologic; Male; Medial Forebrain Bundle; Movement; Oxidopamine; Parkinsonian Disorders; Psychomotor Performance; Rats; Rats, Wistar; Stereotyped Behavior; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase; Videotape Recording

2011
Systemic treatment of focal brain injury in the rat by human umbilical cord blood cells being at different level of neural commitment.
    Acta neurobiologiae experimentalis, 2011, Volume: 71, Issue:1

    Topics: Analysis of Variance; Animals; Antigens, CD34; Apomorphine; Brain Injuries; Cognition Disorders; Disease Models, Animal; Exploratory Behavior; Fetal Blood; Gene Expression Regulation; Hematopoietic Stem Cell Transplantation; Humans; Infusions, Intra-Arterial; Locomotion; Male; Movement Disorders; Nerve Tissue Proteins; Neurons; Neuropsychological Tests; Psychomotor Performance; Rats; Rats, Wistar; Recognition, Psychology; Rotation; Time Factors; Vibrissae

2011
Dopamine release from serotonergic nerve fibers is reduced in L-DOPA-induced dyskinesia.
    Journal of neurochemistry, 2011, Volume: 118, Issue:1

    Topics: Adrenergic Agents; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopa Decarboxylase; Dopamine; Dyskinesia, Drug-Induced; Electrochemistry; Female; Functional Laterality; Levodopa; Oxidopamine; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Severity of Illness Index; Stereotyped Behavior; Tyrosine 3-Monooxygenase

2011
Significant effects of 4-aminopyridine and tetraethylammonium in the treatment of 6-hydroxydopamine-induced Parkinson's disease.
    Behavioural brain research, 2011, Sep-30, Volume: 223, Issue:1

    Topics: 4-Aminopyridine; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Drug Interactions; Male; Medial Forebrain Bundle; Microinjections; Oxidopamine; Parkinson Disease, Secondary; Potassium Channel Blockers; Rats; Rats, Wistar; Tetraethylammonium

2011
Myricitrin, a nitric oxide and protein kinase C inhibitor, exerts antipsychotic-like effects in animal models.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Aug-15, Volume: 35, Issue:7

    Topics: Animals; Antipsychotic Agents; Apomorphine; Arginine; Catalepsy; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flavonoids; Indazoles; Male; Mice; Motor Activity; Nitric Oxide; Phytotherapy; Plant Leaves; Plant Preparations; Protein Kinase C; Psychotic Disorders; Rats; Rats, Wistar; Stereotyped Behavior; Syzygium; Tamoxifen

2011
Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Sequard syndrome.
    Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Brown-Sequard Syndrome; Clonidine; Disease Models, Animal; Dopamine Agonists; Drug Interactions; Female; Functional Laterality; Methoxamine; Motor Activity; Motor Neurons; Movement Disorders; Quipazine; Rats; Rats, Inbred Lew; Recovery of Function; Serotonin; Serotonin Receptor Agonists; Spinal Cord Injuries; Sympatholytics; Sympathomimetics; Tyrosine 3-Monooxygenase

2011
Effects of chronic, systemic treatment with the dopamine receptor agonist R-apomorphine in partially lesioned rat model of Parkinson's disease: an electrophysiological study of substantia nigra dopamine neurons.
    The Chinese journal of physiology, 2011, Apr-30, Volume: 54, Issue:2

    Topics: Action Potentials; Animals; Apomorphine; Cell Count; Disease Models, Animal; Dopamine Agonists; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase

2011
Characterizing the spontaneous blink generator: an animal model.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Aug-03, Volume: 31, Issue:31

    Topics: Adult; Animals; Apomorphine; Blinking; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dry Eye Syndromes; Electric Stimulation; Electromyography; Female; Fourier Analysis; Functional Laterality; Haloperidol; Humans; Magnetics; Male; Middle Aged; Rats; Time Factors; Trigeminal Nerve; Young Adult

2011
Neuroprotective effects of neurokinin receptor one in dopaminergic neurons are mediated through Akt/PKB cell signaling pathway.
    Neuropharmacology, 2011, Volume: 61, Issue:8

    Topics: Analysis of Variance; Animals; Apomorphine; bcl-Associated Death Protein; Caspase 3; Cell Death; Cell Line, Tumor; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation; L-Lactate Dehydrogenase; Male; Motor Activity; Neuroblastoma; Neurokinin-1 Receptor Antagonists; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidopamine; Peptide Fragments; Proto-Oncogene Proteins c-akt; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Rotarod Performance Test; Signal Transduction; Substance P; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase

2011
Extent of pre-operative L-DOPA-induced dyskinesia predicts the severity of graft-induced dyskinesia after fetal dopamine cell transplantation.
    Experimental neurology, 2011, Volume: 232, Issue:2

    Topics: Amphetamines; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Dopaminergic Neurons; Dyskinesia, Drug-Induced; Dyskinesias; Female; Fetal Tissue Transplantation; Levodopa; Oxidopamine; Postoperative Complications; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Substantia Nigra; Sympatholytics

2011
The involvement of RGS9 in l-3,4-dihydroxyphenylalanine-induced dyskinesias in unilateral 6-OHDA lesion rat model.
    Brain research bulletin, 2011, Nov-25, Volume: 86, Issue:5-6

    Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Benserazide; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RGS Proteins

2011
Adh1 and Adh1/4 knockout mice as possible rodent models for presymptomatic Parkinson's disease.
    Behavioural brain research, 2012, Feb-01, Volume: 227, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Dehydrogenase; Analysis of Variance; Animals; Apomorphine; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dopamine Agonists; Electrochemical Techniques; Exploratory Behavior; Female; Genotype; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Olfaction Disorders; Parkinson Disease; Smell; Time Factors

2012
Effects of sertraline on experimental mouse models of psychosis.
    Neurosciences (Riyadh, Saudi Arabia), 2012, Volume: 17, Issue:1

    Topics: Animals; Antidepressive Agents; Apomorphine; Catalepsy; Dextroamphetamine; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Haloperidol; Mice; Motor Activity; Psychotic Disorders; Selective Serotonin Reuptake Inhibitors; Sertraline; Time Factors

2012
Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity.
    Physiology & behavior, 2012, Jul-16, Volume: 106, Issue:5

    Topics: Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Body Weight; Corticosterone; Disease Models, Animal; Dopamine Agonists; Exploratory Behavior; Eye; Inhibition, Psychological; Psychopathology; Rats; Rats, Wistar; Reflex, Startle; Sensory Gating; Social Isolation; Stress, Psychological; Weaning

2012
Sedative, antiepileptic and antipsychotic effects of Viscum album L. (Loranthaceae) in mice and rats.
    Journal of ethnopharmacology, 2012, Jun-14, Volume: 141, Issue:3

    Topics: Animals; Anticonvulsants; Antipsychotic Agents; Apomorphine; Catalepsy; Disease Models, Animal; Epilepsy; Female; Haloperidol; Hypnotics and Sedatives; Isoniazid; Male; Mice; Motor Activity; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Sleep; Viscum album

2012
Behavioral and histological analysis of a partial double-lesion model of parkinson-variant multiple system atrophy.
    Journal of neuroscience research, 2012, Volume: 90, Issue:6

    Topics: Animals; Apomorphine; Cell Count; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Exploratory Behavior; Female; Functional Laterality; Gait Disorders, Neurologic; Motor Activity; Multiple System Atrophy; Oxidopamine; Parkinson Disease; Psychomotor Performance; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase

2012
High intake of folic acid or complex of B vitamins provides anti-Parkinsonism effect: no role for serum level of homocysteine.
    Behavioural brain research, 2012, Aug-01, Volume: 233, Issue:2

    Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Apomorphine; Area Under Curve; Disease Models, Animal; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Folic Acid; Homocysteine; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Statistics, Nonparametric; Stereotyped Behavior; Vitamin B Complex

2012
Chronic high-frequency stimulation therapy in hemiparkinsonian rhesus monkeys using an implanted human DBS system.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013, Volume: 34, Issue:5

    Topics: Animals; Apomorphine; Cerebral Angiography; Deep Brain Stimulation; Disease Models, Animal; Electrodes, Implanted; Follow-Up Studies; Functional Laterality; Gliosis; Macaca mulatta; Male; Movement; Parkinsonian Disorders; Rotation; Subthalamic Nucleus; Time Factors

2013
Increased dopamine receptor activity in the nucleus accumbens shell ameliorates anxiety during drug withdrawal.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:11

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anxiety; Apomorphine; Benzazepines; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Male; Morphine; Nucleus Accumbens; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reflex, Startle; Substance Withdrawal Syndrome

2012
Antipsychotic and sedative effects of the leaf extract of Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae) in rodents.
    Journal of ethnopharmacology, 2012, Aug-30, Volume: 143, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Asteraceae; Behavior, Animal; Body Temperature; Brain; Catalepsy; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agents; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Medicine, African Traditional; Mice; Mice, Inbred Strains; Motor Activity; Pentobarbital; Phytotherapy; Plant Extracts; Plant Leaves; Psychotic Disorders; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Valproic Acid

2012
Anti-apoptotic and anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's rat model.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:4

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Apomorphine; Apoptosis; Behavior, Animal; Benzodioxoles; Disease Models, Animal; Male; Oxidative Stress; Oxidopamine; Parkinson Disease; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Wistar

2013
Synthesis and evaluation of a series of piperidine-2,6-dione-piperazine (piperidine) derivatives as multireceptor atypical antipsychotics.
    Archiv der Pharmazie, 2012, Volume: 345, Issue:11

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Mice; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Histamine H1; Receptors, Serotonin; Structure-Activity Relationship

2012
Survival and functional restoration of human fetal ventral mesencephalon following transplantation in a rat model of Parkinson's disease.
    Cell transplantation, 2013, Volume: 22, Issue:7

    Topics: Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Embryo, Mammalian; Female; Graft Survival; Humans; Mesencephalon; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Transplantation, Heterologous; Tyrosine 3-Monooxygenase

2013
New insights into pharmacological profile of LASSBio-579, a multi-target N-phenylpiperazine derivative active on animal models of schizophrenia.
    Behavioural brain research, 2013, Jan-15, Volume: 237

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antipsychotic Agents; Apomorphine; Barbiturates; Catalepsy; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Hypothermia; Ketamine; Male; Mice; Motor Activity; Piperazines; Psychoacoustics; Reflex, Startle; Schizophrenia; Sleep

2013
Fucoidan protects against lipopolysaccharide-induced rat neuronal damage and inhibits the production of proinflammatory mediators in primary microglia.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:10

    Topics: Analysis of Variance; Animals; Apomorphine; Brain Injuries; CD11b Antigen; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Lipopolysaccharides; Male; Mental Disorders; Microglia; Neuroprotective Agents; Polysaccharides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stereotyped Behavior; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase

2012
High frequency electro-acupuncture enhances striatum DAT and D1 receptor expression, but decreases D2 receptor level in 6-OHDA lesioned rats.
    Behavioural brain research, 2013, Jan-15, Volume: 237

    Topics: Acupuncture Points; Acupuncture Therapy; Analysis of Variance; Animals; Apomorphine; Biophysical Phenomena; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Gene Expression Regulation; Male; Movement Disorders; Neurons; Neurotoxicity Syndromes; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Sympatholytics

2013
Transplantation of neural stem cells co-transfected with Nurr1 and Brn4 for treatment of Parkinsonian rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2013, Volume: 31, Issue:1

    Topics: Adrenergic Agents; Animals; Apomorphine; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Green Fluorescent Proteins; Male; Nerve Tissue Proteins; Nuclear Receptor Subfamily 4, Group A, Member 2; Oxidopamine; Parkinsonian Disorders; POU Domain Factors; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Time Factors; Transfection; Tyrosine 3-Monooxygenase

2013
Aquaporin-4 knockout abolishes apomorphine-induced tardive dyskinesia following chronic treatment with neuroleptics.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:12

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Antipsychotic Agents; Apomorphine; Aquaporin 4; Clozapine; Corpus Striatum; Disease Models, Animal; Glial Fibrillary Acidic Protein; Haloperidol; Hippocampus; Male; Mastication; Mice; Mice, Knockout; Motor Activity; Movement Disorders

2012
Is nicotine protective against Parkinson's disease? An experimental analysis.
    CNS & neurological disorders drug targets, 2012, Nov-01, Volume: 11, Issue:7

    Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Interneurons; Male; Nerve Tissue Proteins; Neuroprotective Agents; Nicotine; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra

2012
Neural stem cells transplanted in a mouse model of Parkinson's disease differentiate to neuronal phenotypes and reduce rotational deficit.
    CNS & neurological disorders drug targets, 2012, Nov-01, Volume: 11, Issue:7

    Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Cell Differentiation; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Embryo, Mammalian; GABAergic Neurons; Graft Survival; Green Fluorescent Proteins; Membrane Proteins; Mice; Mice, Inbred Strains; Mice, Transgenic; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Oxidopamine; Parkinson Disease; Substantia Nigra; Tubulin

2012
Dopaminergic neuronal loss and dopamine-dependent locomotor defects in Fbxo7-deficient zebrafish.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Animals; Apomorphine; Body Patterning; Brain; Disease Models, Animal; Domperidone; Dopamine; Dopamine Antagonists; Exons; Expressed Sequence Tags; F-Box Proteins; Humans; Immunohistochemistry; In Situ Hybridization; Introns; Locomotion; Neurons; Parkinsonian Disorders; Phenotype; Protein Structure, Tertiary; RNA, Messenger; Zebrafish

2012
Therapeutic deep brain stimulation in Parkinsonian rats directly influences motor cortex.
    Neuron, 2012, Dec-06, Volume: 76, Issue:5

    Topics: Action Potentials; Adrenergic Agents; Afferent Pathways; Animals; Antiparkinson Agents; Apomorphine; Biophysics; Brain Mapping; Deep Brain Stimulation; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Evoked Potentials, Motor; Functional Laterality; Locomotion; Male; Medial Forebrain Bundle; Motor Cortex; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Statistics as Topic; Subthalamic Nucleus

2012
Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish model.
    Annals of neurology, 2013, Volume: 73, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Apomorphine; Disease Models, Animal; Dopamine Agonists; Genes, Reporter; Glycine; HSP72 Heat-Shock Proteins; Humans; Interneurons; Mice; Motor Neurons; Muscle, Skeletal; Neuromuscular Junction; Neuroprotective Agents; NF-E2-Related Factor 2; Patch-Clamp Techniques; Riluzole; Stress, Physiological; Superoxide Dismutase; Superoxide Dismutase-1; Zebrafish; Zebrafish Proteins

2013
Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia.
    Movement disorders : official journal of the Movement Disorder Society, 2013, Volume: 28, Issue:8

    Topics: Amantadine; Amphetamine; Animals; Apomorphine; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Medial Forebrain Bundle; Motor Activity; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Piperazines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Time Factors; Tyrosine 3-Monooxygenase

2013
BDNF receptor blockade hinders the beneficial effects of exercise in a rat model of Parkinson's disease.
    Neuroscience, 2013, May-01, Volume: 237

    Topics: Analysis of Variance; Animals; Apomorphine; Carbazoles; Corpus Striatum; Disease Models, Animal; Enzyme Inhibitors; Exercise Test; Exercise Therapy; Gene Expression Regulation; Indole Alkaloids; Male; Oxidopamine; Parkinson Disease; Putamen; Rats; Rats, Wistar; Receptor, trkB; Stereotyped Behavior; Time Factors; Tyrosine 3-Monooxygenase

2013
Forced nonuse in unilateral parkinsonian rats exacerbates injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Aug-01, Volume: 22, Issue:15

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Casts, Surgical; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Forelimb; Homovanillic Acid; Membrane Glycoproteins; Membrane Transport Proteins; Movement; Nerve Tissue Proteins; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Physical Exertion; Rats; Rats, Long-Evans; Restraint, Physical; Tyrosine 3-Monooxygenase; Vesicular Biogenic Amine Transport Proteins

2002
Ciliary neurotrophic factor overexpression in neural progenitor cells (ST14A) increases proliferation, metabolic activity, and resistance to stress during differentiation.
    Journal of neuroscience research, 2003, Jan-15, Volume: 71, Issue:2

    Topics: Animals; Apomorphine; Apoptosis; Blotting, Western; Cell Differentiation; Cell Division; Cells, Cultured; Ciliary Neurotrophic Factor; Coculture Techniques; Corpus Striatum; Culture Media, Serum-Free; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Gene Expression; In Situ Nick-End Labeling; Quinolinic Acid; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotation; Staurosporine; Stem Cells; Stress, Physiological; Tetrazolium Salts; Thermosensing; Thymidine; Time Factors; Transfection; Tritium

2003
Both short- and long-acting D-1/D-2 dopamine agonists induce less dyskinesia than L-DOPA in the MPTP-lesioned common marmoset (Callithrix jacchus).
    Experimental neurology, 2003, Volume: 179, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Callithrix; Disability Evaluation; Disease Models, Animal; Dopamine Agonists; Dyskinesia, Drug-Induced; Levodopa; Motor Activity; Parkinsonian Disorders; Pergolide; Receptors, Dopamine D1; Receptors, Dopamine D2; Severity of Illness Index

2003
A novel skilled-reaching impairment in paw supination on the "good" side of the hemi-Parkinson rat improved with rehabilitation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jan-15, Volume: 23, Issue:2

    Topics: Animals; Apomorphine; Behavior Control; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Feeding Behavior; Female; Forelimb; Functional Laterality; Motor Skills; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Long-Evans; Recovery of Function; Substantia Nigra; Supination

2003
Relationships between various behavioural abnormalities and nigrostriatal dopamine depletion in the unilateral 6-OHDA-lesioned rat.
    Behavioural brain research, 2003, Feb-17, Volume: 139, Issue:1-2

    Topics: Animals; Apomorphine; Behavior, Animal; Cell Death; Disease Models, Animal; Dopamine; Female; Functional Laterality; Neostriatum; Neurons; Orientation; Oxidopamine; Parkinsonian Disorders; Perceptual Disorders; Postural Balance; Posture; Rats; Rats, Sprague-Dawley; Substantia Nigra

2003
Acupuncture prevents 6-hydroxydopamine-induced neuronal death in the nigrostriatal dopaminergic system in the rat Parkinson's disease model.
    Experimental neurology, 2003, Volume: 180, Issue:1

    Topics: Acupuncture Therapy; Animals; Apomorphine; Behavior, Animal; Cell Count; Cell Survival; Corpus Striatum; Disease Models, Animal; Dopamine; Immunohistochemistry; Male; Motor Activity; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptor, trkB; Substantia Nigra; Tyrosine 3-Monooxygenase

2003
Differential sensitivity to acute administration of Ritalin, apomorphine, SCH 23390, but not raclopride in mice selectively bred for hyperactive wheel-running behavior.
    Psychopharmacology, 2003, Volume: 167, Issue:3

    Topics: Animals; Animals, Outbred Strains; Apomorphine; Benzazepines; Breeding; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Hyperkinesis; Male; Methylphenidate; Mice; Motor Activity; Raclopride; Selection, Genetic; Species Specificity; Time Factors

2003
Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF.
    Journal of neurochemistry, 2003, Volume: 85, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Casts, Surgical; Corpus Striatum; Disease Models, Animal; Dopamine; Forelimb; Functional Laterality; Glial Cell Line-Derived Neurotrophic Factor; Immobilization; Male; Medial Forebrain Bundle; Motor Activity; Nerve Growth Factors; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Long-Evans; Rats, Sprague-Dawley

2003
Deficient prepulse inhibition of acoustic startle in Hooded-Wistar rats compared with Sprague-Dawley rats.
    Clinical and experimental pharmacology & physiology, 2003, Volume: 30, Issue:4

    Topics: Acoustic Stimulation; Amphetamine; Animals; Anxiety; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Maze Learning; Motor Activity; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reflex, Startle; Schizophrenia; Species Specificity

2003
EEG modifications in the cortex and striatum after dopaminergic priming in the 6-hydroxydopamine rat model of Parkinson's disease.
    Brain research, 2003, May-16, Volume: 972, Issue:1-2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley

2003
Convulsive and postural effects of lesioning the mid-substantia nigra pars reticulata in naïve and 6-hydroxydopamine lesioned rats.
    Brain research bulletin, 2003, Apr-15, Volume: 60, Issue:1-2

    Topics: Animals; Apomorphine; Behavior, Animal; Cortical Synchronization; Disease Models, Animal; Dopamine Agonists; Female; Functional Laterality; Kainic Acid; Motor Activity; Oxidopamine; Parkinsonian Disorders; Perceptual Disorders; Posture; Rats; Rats, Sprague-Dawley; Rotation; Seizures; Substantia Nigra

2003
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
    Neuroscience and behavioral physiology, 2003, Volume: 33, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Apomorphine; Avoidance Learning; Biguanides; Brain Chemistry; Chlordiazepoxide; Clonidine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memantine; Mephenytoin; Microinjections; Pentylenetetrazole; Phentolamine; Picrotoxin; Piperazines; Propranolol; Pyrimidines; Rats; Serotonin; Sulpiride; Ventromedial Hypothalamic Nucleus; Yohimbine

2003
[A new vomiting animal model--mink].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:2

    Topics: Animals; Antiemetics; Apomorphine; Cisplatin; Copper Sulfate; Disease Models, Animal; Male; Metoclopramide; Mink; Ondansetron; Vomiting

2003
Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression.
    Journal of neurochemistry, 2003, Volume: 85, Issue:6

    Topics: Animals; Antigens, Differentiation; Apomorphine; Ascorbic Acid; Astrocytes; Cell Differentiation; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Dopamine; Gene Expression; Gestational Age; Graft Survival; Male; Mesencephalon; Motor Activity; Neurons; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Retroviridae; Stem Cell Transplantation; Stem Cells; Transcription Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase

2003
Neurodegeneration of substantia nigra accompanied with macrophage/microglia infiltration after intrastriatal hemorrhage.
    Neuroscience research, 2003, Volume: 46, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Brain-Derived Neurotrophic Factor; Central Nervous System Stimulants; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Dopamine Agonists; Ectodysplasins; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Immunohistochemistry; In Situ Hybridization; Macrophages; Male; Membrane Proteins; Methamphetamine; Microglia; Mitogen-Activated Protein Kinases; Nerve Degeneration; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; RNA, Messenger; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2003
Riluzole, an inhibitor of glutamatergic transmission, suppresses levodopa-induced rotations in 6-hydroxydopamine-lesioned rats.
    Pharmacology & toxicology, 2003, Volume: 93, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Riluzole; Synaptic Transmission

2003
Dopamine depletion abolishes apomorphine- and amphetamine-induced increases in extracellular serotonin levels in the striatum of conscious rats: a microdialysis study.
    Neuroscience, 2003, Volume: 119, Issue:4

    Topics: Afferent Pathways; Amphetamine; Animals; Apomorphine; Binding, Competitive; Carrier Proteins; Denervation; Disease Models, Animal; Dopamine; Dopamine Agonists; Extracellular Matrix; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Neostriatum; Nerve Tissue Proteins; Neuronal Plasticity; Oxidopamine; Parkinsonian Disorders; Paroxetine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptic Transmission

2003
Dopamine release rather than content in the caudate putamen is associated with behavioral changes in the iron rat model of Parkinson's disease.
    Experimental neurology, 2003, Volume: 182, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Caudate Nucleus; Chlorides; Deferoxamine; Disease Models, Animal; Dopamine; Drug Administration Routes; Female; Ferric Compounds; Iron; Iron Chelating Agents; Parkinsonian Disorders; Putamen; Rats; Rats, Sprague-Dawley

2003
Treatment effects on nigrostriatal projection integrity in partial 6-OHDA lesions: comparison of L-DOPA and pramipexole.
    Experimental neurology, 2003, Volume: 183, Issue:1

    Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Autoradiography; Behavior, Animal; Benzothiazoles; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Pramipexole; Rats; Rats, Sprague-Dawley; Substantia Nigra; Thiazoles; Treatment Outcome; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2003
Effect of gamma-hydroxybutyrate in two rat models of focal cerebral damage.
    Brain research, 2003, Oct-03, Volume: 986, Issue:1-2

    Topics: Animals; Apomorphine; Brain; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Kainic Acid; Learning; Male; Memory Disorders; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Sodium Oxybate

2003
Dopaminergic trophism after intrastriatal injection of lentivirus-transferred GDNF in Parkinson rat model.
    Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica, 2003, Volume: 35, Issue:10

    Topics: Animals; Apomorphine; Behavior, Animal; Cell Line; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Humans; Immunohistochemistry; Lentivirus; Male; Nerve Growth Factors; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase

2003
"Hydrocephalus-parkinsonism complex": progressive hydrocephalus as a factor affecting extrapyramidal tract disorder-an experimental study.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2004, Volume: 20, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Behavior, Animal; Disease Models, Animal; Drug Interactions; Functional Laterality; Hydrocephalus; Kaolin; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Time Factors

2004
Uptake of 6-[18F]fluoro-L-dopa and [18F]CFT reflect nigral neuronal loss in a rat model of Parkinson's disease.
    Synapse (New York, N.Y.), 2004, Volume: 51, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Behavior, Animal; Brain; Brain Mapping; Central Nervous System Stimulants; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine Agonists; Functional Laterality; Immunohistochemistry; Levodopa; Male; Oxidopamine; Parkinson Disease; Propionates; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase

2004
The effects of chronic L-DOPA therapy on pharmacodynamic parameters in a rat model of motor response fluctuations.
    Experimental neurology, 2003, Volume: 184, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Autoradiography; Benzamides; Disease Models, Animal; Dopamine Agonists; Dyskinesias; Female; Forelimb; Immunohistochemistry; Levodopa; Medial Forebrain Bundle; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Presynaptic

2003
Effects of electrolytic and 6-hydroxydopamine lesions of rat nigrostriatal pathway on nitric oxide synthase and nicotinamide adenine dinucleotide phosphate diaphorase.
    Brain research bulletin, 2003, Dec-15, Volume: 62, Issue:2

    Topics: Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Electric Injuries; Functional Laterality; Immunohistochemistry; Injections, Intraventricular; Male; Microelectrodes; NADPH Dehydrogenase; Nitric Oxide Synthase; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar

2003
Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats.
    Neurobiology of disease, 2003, Volume: 14, Issue:3

    Topics: Adenoviridae; Animals; Apomorphine; Cell Death; Cell Survival; Corpus Striatum; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Infarction, Middle Cerebral Artery; Lentivirus; Male; Movement Disorders; Nerve Degeneration; Nerve Growth Factors; Rats; Rats, Wistar; Stroke; Transduction, Genetic; Treatment Failure; Up-Regulation

2003
Altered prepulse inhibition in rats treated prenatally with the antimitotic Ara-C: an animal model for sensorimotor gating deficits in schizophrenia.
    Psychopharmacology, 2004, Volume: 174, Issue:2

    Topics: Animals; Antineoplastic Agents; Apomorphine; Brain; Cytarabine; Disease Models, Animal; Dopamine Agonists; Drug Interactions; Female; Hallucinogens; Male; Maternal-Fetal Exchange; Phencyclidine; Pregnancy; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia

2004
Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinson's disease.
    Experimental neurology, 2004, Volume: 187, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Callithrix; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Synergism; Levodopa; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Phenols; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2004
Pituitary adenylate cyclase activating polypeptide protects dopaminergic neurons and improves behavioral deficits in a rat model of Parkinson's disease.
    Behavioural brain research, 2004, May-05, Volume: 151, Issue:1-2

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Behavioral Symptoms; Disease Models, Animal; Dopamine; Dopamine Agonists; Drug Interactions; Immunohistochemistry; Male; Motor Activity; Neurons; Neuropeptides; Oxidopamine; Parkinson Disease; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2004
Autoimmune-induced damage of the midbrain dopaminergic system in lupus-prone mice.
    Journal of neuroimmunology, 2004, Volume: 152, Issue:1-2

    Topics: Age Factors; Animals; Apomorphine; Autoantibodies; Autoimmunity; Behavior, Animal; Cerebrospinal Fluid; Cyclophosphamide; Disease Models, Animal; Dopamine; Dopamine Agonists; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Male; Mesencephalon; Mice; Mice, Inbred MRL lpr; Nerve Degeneration; Neurons; Tumor Necrosis Factor-alpha

2004
Modifications of local cerebral glucose utilization in thalamic structures following injection of a dopaminergic agonist in the nucleus accumbens--involvement in antiepileptic effects?
    Experimental neurology, 2004, Volume: 188, Issue:2

    Topics: Animals; Apomorphine; Autoradiography; Basal Ganglia; Deoxyglucose; Disease Models, Animal; Dopamine Agonists; Electroencephalography; Epilepsy, Absence; GABA Agonists; Glucose; Male; Microinjections; Muscimol; Nucleus Accumbens; Rats; Rats, Inbred Strains; Rats, Wistar; Thalamic Nuclei; Thalamus

2004
Prepulse inhibition of acoustic startle in spontaneously hypertensive rats.
    Behavioural brain research, 2004, Oct-05, Volume: 154, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Radiation; Excitatory Amino Acid Antagonists; Hypertension; Male; Neural Inhibition; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Reflex, Acoustic; Reflex, Startle; Serotonin Receptor Agonists; Species Specificity

2004
Neuroprotective effect of L-DOPA co-administered with the adenosine A2A receptor agonist CGS 21680 in an animal model of Parkinson's disease.
    Brain research bulletin, 2004, Aug-30, Volume: 64, Issue:2

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Analysis of Variance; Animals; Antiparkinson Agents; Apomorphine; Cell Count; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Drug Therapy, Combination; Dyskinesias; Immunohistochemistry; Levodopa; Male; Oxidopamine; Parkinson Disease; Phenethylamines; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase

2004
Effects of neonatal excitotoxic lesions of the entorhinal cortex on cognitive functions in the adult rat.
    Neuroscience, 2004, Volume: 128, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Apomorphine; Cognition; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Entorhinal Cortex; Ibotenic Acid; Male; Maze Learning; Memory; Motivation; Motor Activity; Neurotoxins; Rats; Rats, Wistar; Reflex, Startle; Schizophrenic Psychology

2004
Electron spin resonance spectroscopy reveals alpha-phenyl-N-tert-butylnitrone spin-traps free radicals in rat striatum and prevents haloperidol-induced vacuous chewing movements in the rat model of human tardive dyskinesia.
    Synapse (New York, N.Y.), 2004, Dec-01, Volume: 54, Issue:3

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Binding Sites; Corpus Striatum; Cyclic N-Oxides; Disease Models, Animal; Dopamine Agonists; Drug Interactions; Dyskinesia, Drug-Induced; Electron Spin Resonance Spectroscopy; Haloperidol; Humans; Male; Mastication; Motor Activity; Movement Disorders; Neuroprotective Agents; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Dopamine D2

2004
Neuroprotective and neurotrophic effect of apomorphine in the striatal 6-OHDA-lesion rat model of Parkinson's disease.
    Brain research, 2004, Nov-05, Volume: 1026, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Disease Models, Animal; Dopamine; Drug Interactions; Electrochemistry; Hydroxybenzoates; Immunohistochemistry; Male; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Wistar; Stereotyped Behavior; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2004
Preserved ipsilateral-to-lesion motor map organization in the unilateral 6-OHDA-treated rat model of Parkinson's disease.
    Brain research, 2004, Nov-05, Volume: 1026, Issue:1

    Topics: Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Brain; Brain Mapping; Cell Count; Disease Models, Animal; Dopamine; Electric Stimulation; Forelimb; Functional Laterality; Immunohistochemistry; Male; Movement; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Long-Evans; Rotation; Sympatholytics; Tyrosine 3-Monooxygenase

2004
Delayed onset of prepulse inhibition deficits following kainic acid treatment on postnatal day 7 in rats.
    The European journal of neuroscience, 2004, Volume: 20, Issue:10

    Topics: Acoustic Stimulation; Age Factors; Amphetamine; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Exploratory Behavior; Female; Hippocampus; Inhibition, Psychological; Kainic Acid; Limbic System; Male; Maze Learning; Motor Activity; Pregnancy; Rats; Rats, Long-Evans; Reaction Time; Reflex, Startle; Schizophrenia

2004
The development of various somatic markers is retarded in an animal model for schizophrenia, namely apomorphine-susceptible rats.
    Behavioural brain research, 2005, Feb-28, Volume: 157, Issue:2

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Biomarkers; Disease Models, Animal; Dopamine Agonists; Female; Genotype; Handling, Psychological; Male; Phenotype; Rats; Rats, Inbred Strains; Schizophrenia; Species Specificity; Stereotyped Behavior; Stress, Psychological

2005
Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate.
    Journal of molecular neuroscience : MN, 2004, Volume: 24, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Apomorphine; Catechin; Disease Models, Animal; Free Radicals; Iron; Iron Chelating Agents; Lewy Bodies; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Substantia Nigra; Synucleins; Ubiquitin

2004
Continuous dopaminergic stimulation reduces risk of motor complications in parkinsonian primates.
    Experimental neurology, 2005, Volume: 192, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Implants; Dyskinesias; Inflammation; Injections, Subcutaneous; Macaca fascicularis; Male; Movement; Parkinsonian Disorders; Polyvinyls; Recovery of Function; Steroids

2005
Altered extracellular striatal in vivo biotransformation of the opioid neuropeptide dynorphin A(1-17) in the unilateral 6-OHDA rat model of Parkinson's disease.
    Journal of mass spectrometry : JMS, 2005, Volume: 40, Issue:2

    Topics: Amino Acid Sequence; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Chromatography, Liquid; Corpus Striatum; Disease Models, Animal; Dynorphins; Mass Spectrometry; Microdialysis; Molecular Sequence Data; Oxidopamine; Parkinson Disease; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization

2005
Gene dosage effect on gamma-secretase component Aph-1b in a rat model for neurodevelopmental disorders.
    Neuron, 2005, Feb-17, Volume: 45, Issue:4

    Topics: Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Apomorphine; Aspartic Acid Endopeptidases; Base Sequence; Behavior, Animal; Blotting, Northern; Blotting, Western; Disease Models, Animal; Endopeptidases; Exons; Gene Dosage; Genetic Predisposition to Disease; Genotype; Humans; Membrane Proteins; Oligonucleotide Array Sequence Analysis; Peptide Hydrolases; Phenotype; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schizophrenia; Species Specificity; Stereotyped Behavior

2005
Levodopa in the treatment of Parkinson's disease: current controversies.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:5

    Topics: Animals; Antiparkinson Agents; Apomorphine; Disease Models, Animal; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Haplorhini; Levodopa; Lisuride; Parkinson Disease; Pergolide

2005
Failure of FK506 (tacrolimus) to alleviate apomorphine-induced circling in rat Parkinson model in spite of some cytoprotective effects in SH-SY5Y dopaminergic cells.
    Brain research, 2005, Mar-15, Volume: 1038, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Caspase 3; Caspases; Cell Death; Cell Line, Tumor; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Immunophilins; Male; Motor Activity; Nerve Degeneration; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Random Allocation; Rats; Rats, Wistar; Tacrolimus

2005
Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences.
    Journal of neurochemistry, 2005, Volume: 93, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Catecholamines; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Ginkgo biloba; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Immunohistochemistry; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Plant Extracts; Psychomotor Performance; Rats; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior; Substantia Nigra; Thiobarbituric Acid Reactive Substances; Tyrosine 3-Monooxygenase

2005
Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model.
    Neuroscience research, 2005, Volume: 52, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Cell Count; Cells, Cultured; Corpus Striatum; Disease Models, Animal; DNA-Binding Proteins; Dopamine and cAMP-Regulated Phosphoprotein 32; Drosophila Proteins; Endogenous Retroviruses; Functional Laterality; Galactosides; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Humans; Huntington Disease; Immunohistochemistry; Indoles; Infusions, Intravenous; Male; Motor Activity; Nerve Tissue Proteins; Neurons; Parvalbumins; Phosphoproteins; Phosphopyruvate Hydratase; Quinolinic Acid; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotarod Performance Test; Stem Cell Transplantation; Stem Cells; Time Factors

2005
Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice.
    Behavioural brain research, 2005, Jul-01, Volume: 162, Issue:1

    Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Cell Count; Disease Models, Animal; Drug Interactions; Exploratory Behavior; Female; Functional Laterality; Immunohistochemistry; Linear Models; Medial Forebrain Bundle; Mice; Mice, Inbred CBA; Motor Activity; Neurons; Oxidopamine; Parkinson Disease; Predictive Value of Tests; Psychomotor Performance; Rotarod Performance Test; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2005
Behavioural effects of parafascicular thalamic lesions in an animal model of parkinsonism.
    Behavioural brain research, 2005, Jul-30, Volume: 162, Issue:2

    Topics: Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Choice Behavior; Disease Models, Animal; Female; Grooming; Medial Forebrain Bundle; Motor Activity; Oxidopamine; Parkinsonian Disorders; Piloerection; Posture; Rats; Rats, Sprague-Dawley; Reaction Time; Reinforcement, Psychology; Stereotyped Behavior; Thalamic Nuclei; Vibrissae

2005
Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease.
    Brain research, 2005, Aug-09, Volume: 1052, Issue:2

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cell Count; Cell Line; Corpus Striatum; Cricetinae; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Immunohistochemistry; Nerve Growth Factors; Neurons; Oxidopamine; Parkinson Disease; Rats; Rotation; Simplexvirus; Substantia Nigra

2005
Individual differences in male rat ejaculatory behaviour: searching for models to study ejaculation disorders.
    The European journal of neuroscience, 2005, Volume: 22, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Brain; Cell Count; Disease Models, Animal; Dopamine Agonists; Drug Interactions; Ejaculation; Exploratory Behavior; Female; Immunohistochemistry; Male; Maze Learning; Oncogene Proteins v-fos; Oxytocin; Rats; Rats, Wistar; Reaction Time; Serotonin Receptor Agonists; Sexual Behavior, Animal; Sexual Dysfunction, Physiological; Stereotyped Behavior

2005
The unilateral 6-OHDA rat model of Parkinson's disease revisited: an electromyographic and behavioural analysis.
    The European journal of neuroscience, 2005, Volume: 22, Issue:3

    Topics: Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Electromyography; Extremities; Female; Functional Laterality; Locomotion; Muscle, Skeletal; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Inbred Lew; Stereotyped Behavior; Substantia Nigra

2005
Differential expression of striatal synaptotagmin mRNA isoforms in hemiparkinsonian rats.
    Neuroscience, 2005, Volume: 135, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Benzazepines; Brain; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Female; Gene Expression; Gene Expression Regulation; In Situ Hybridization; Levodopa; Oxidopamine; Parkinsonian Disorders; Protein Isoforms; Rats; Rats, Wistar; RNA, Messenger; Rotation; Substantia Nigra; Synaptotagmins; Time Factors; Tyrosine 3-Monooxygenase

2005
Effects of systemic administration of iptakalim on extracellular neurotransmitter levels in the striatum of unilateral 6-hydroxydopamine-lesioned rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:5

    Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Apomorphine; Astrocytes; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Extracellular Fluid; Glutamic Acid; Male; Microdialysis; Neurotransmitter Agents; Parkinsonian Disorders; Pinacidil; Potassium Channels, Inwardly Rectifying; Presynaptic Terminals; Propylamines; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2006
Transplants of neurosphere cell suspensions from aged mice are functional in the mouse model of Parkinson's.
    Brain research, 2005, Sep-28, Volume: 1057, Issue:1-2

    Topics: Aging; Amphetamine; Animals; Apomorphine; Astrocytes; Behavior, Animal; Behavioral Symptoms; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Functional Laterality; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurofilament Proteins; Neurons; Oxidopamine; Parkinson Disease; Stem Cell Transplantation; Time Factors; Tyrosine 3-Monooxygenase

2005
Different adaptations in ventral tegmental area dopamine neurons in control and ethanol exposed rats after methylphenidate treatment.
    Biological psychiatry, 2006, Apr-01, Volume: 59, Issue:7

    Topics: Action Potentials; Animals; Animals, Newborn; Apomorphine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Depressants; Central Nervous System Stimulants; Disease Models, Animal; Dopamine; Dopamine Agonists; Electrodes, Implanted; Ethanol; Female; Methylphenidate; Neurons; Pregnancy; Rats; Ventral Tegmental Area

2006
Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion.
    Experimental neurology, 2006, Volume: 197, Issue:2

    Topics: Analysis of Variance; Animals; Apomorphine; Autoradiography; Behavior, Animal; Cell Count; Corpus Striatum; Disease Models, Animal; Embryo, Mammalian; Functional Laterality; Huntington Disease; Immunohistochemistry; Male; Motor Activity; Neurons; Positron-Emission Tomography; Quinolinic Acid; Radiography; Rats; Rats, Sprague-Dawley; Recovery of Function; Rotarod Performance Test; Stem Cell Transplantation; Stem Cells

2006
Lesions in monkey globus pallidus externus exacerbate parkinsonian symptoms.
    Experimental neurology, 2006, Volume: 199, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Catheter Ablation; Disease Models, Animal; Dopamine Agonists; Globus Pallidus; Macaca mulatta; Movement; Neurons; Parkinson Disease, Secondary

2006
Further validation of the corridor task for assessing deficit and recovery in the hemi-Parkinsonian rat: restoration of bilateral food retrieval by dopamine receptor agonism.
    Behavioural brain research, 2006, May-15, Volume: 169, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Feeding Behavior; Functional Laterality; Homovanillic Acid; Oxidopamine; Parkinson Disease; Rats; Recovery of Function; Reproducibility of Results

2006
Value of mink vomit model in study of anti-emetic drugs.
    World journal of gastroenterology, 2006, Feb-28, Volume: 12, Issue:8

    Topics: Animals; Antiemetics; Apomorphine; Cisplatin; Copper Sulfate; Disease Models, Animal; Enterochromaffin Cells; Immunohistochemistry; Male; Metoclopramide; Mink; Ondansetron; Random Allocation; Reproducibility of Results; Serotonin; Vomiting

2006
Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease.
    Experimental neurology, 2006, Volume: 199, Issue:2

    Topics: Analysis of Variance; Animals; Apomorphine; Brain Tissue Transplantation; Bromodeoxyuridine; Cell Count; Cell Differentiation; Disease Models, Animal; Dopamine Agonists; Huntington Disease; Immunohistochemistry; Male; Motor Activity; Neostriatum; Nerve Tissue Proteins; Neurons; Quinolinic Acid; Rats; Rats, Wistar; Stem Cell Transplantation; Time Factors; Transcription Factors; Tyrosine 3-Monooxygenase

2006
Continuous exposure to glial cell line-derived neurotrophic factor to mature dopaminergic transplants impairs the graft's ability to improve spontaneous motor behavior in parkinsonian rats.
    Neuroscience, 2006, Aug-11, Volume: 141, Issue:1

    Topics: Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Cell Count; Cell Transplantation; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Interactions; Female; Glial Cell Line-Derived Neurotrophic Factor; Green Fluorescent Proteins; Motor Activity; Neurons; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Recovery of Function; Rotarod Performance Test; Transplants; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2006
Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats.
    Neuropharmacology, 2006, Volume: 51, Issue:3

    Topics: Acoustic Stimulation; Adrenergic alpha-Agonists; Analysis of Variance; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Excitatory Amino Acid Antagonists; Gait Disorders, Neurologic; Imidazoles; Isoxazoles; Male; Neural Inhibition; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Reflex, Startle

2006
Control of dopamine-secretion by Tet-Off system in an in vivo model of parkinsonian rat.
    Brain research, 2006, Aug-02, Volume: 1102, Issue:1

    Topics: Animals; Antiporters; Apomorphine; Bacterial Proteins; Behavior, Animal; Cell Transplantation; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Doxycycline; Female; Gene Expression Regulation; Humans; Immunohistochemistry; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotarod Performance Test; Time Factors; Tyrosine 3-Monooxygenase

2006
Neuroprotective effects of caffeine in the model of 6-hydroxydopamine lesion in rats.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 84, Issue:3

    Topics: Animals; Apomorphine; Brain; Brain Diseases; Caffeine; Disease Models, Animal; Dopamine Agents; Male; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar

2006
Sexually dimorphic postural adjustments during vertical behaviour are altered in a unilateral 6-OHDA rat model of Parkinson's disease.
    Behavioural brain research, 2006, Nov-01, Volume: 174, Issue:1

    Topics: Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Biomechanical Phenomena; Disease Models, Animal; Dopamine Agonists; Female; Functional Laterality; Immunohistochemistry; Male; Movement; Oxidopamine; Parkinson Disease; Posture; Psychomotor Performance; Rats; Rats, Long-Evans; Rotarod Performance Test; Sex Characteristics; Sex Factors; Tyrosine 3-Monooxygenase

2006
Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein.
    Neuroscience, 2006, Nov-03, Volume: 142, Issue:4

    Topics: alpha-Synuclein; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benserazide; Brain; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Genetic Predisposition to Disease; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Parkinson Disease; Stereotypic Movement Disorder

2006
Pharmacological characterization of psychosis-like behavior in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amantadine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Callithrix; Disability Evaluation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Female; Grooming; Hallucinations; Levodopa; Parkinsonian Disorders; Psychomotor Agitation; Psychotic Disorders; Statistics, Nonparametric; Stereotyped Behavior

2006
Dopaminergic neuroprotection by neurturin-expressing c17.2 neural stem cells in a rat model of Parkinson's disease.
    Parkinsonism & related disorders, 2007, Volume: 13, Issue:2

    Topics: Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Cell Count; Cell Line; Disease Models, Animal; Dopamine; Male; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Neurturin; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stem Cells; Tyrosine 3-Monooxygenase

2007
Differences in the cellular mechanism underlying the effects of amphetamine on prepulse inhibition in apomorphine-susceptible and apomorphine-unsusceptible rats.
    Psychopharmacology, 2007, Volume: 190, Issue:1

    Topics: alpha-Methyltyrosine; Amphetamine; Animals; Apomorphine; Brain; Central Nervous System Stimulants; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Inhibition, Psychological; Injections, Intraperitoneal; Male; Neurons; Rats; Rats, Inbred Strains; Reflex, Startle; Remoxipride; Reserpine; Schizophrenic Psychology

2007
Loss of dopaminergic responsiveness in a double lesion rat model of the Parkinson variant of multiple system atrophy.
    Movement disorders : official journal of the Movement Disorder Society, 2007, Feb-15, Volume: 22, Issue:3

    Topics: Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Functional Laterality; Levodopa; Male; Multiple System Atrophy; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra

2007
Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson's disease.
    Brain research, 2007, Apr-20, Volume: 1142

    Topics: Animals; Apomorphine; Bone Marrow Transplantation; Cells, Cultured; Disease Models, Animal; Dopamine; Female; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Humans; In Situ Hybridization; Motor Activity; Neurturin; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Stromal Cells; Transfection; Tyrosine 3-Monooxygenase

2007
Effects of engrafted neural stem cells derived from GFP transgenic mice in Parkinson's diseases rats.
    Neuroscience letters, 2007, May-23, Volume: 419, Issue:1

    Topics: Animals; Animals, Newborn; Antiparkinson Agents; Apomorphine; Behavior, Animal; Disease Models, Animal; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Mice; Mice, Transgenic; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stem Cells; Stereotyped Behavior; Sympatholytics; Time Factors; Transplantation, Heterologous; Tyrosine 3-Monooxygenase

2007
Effects of apomorphine on the expression of learned helplessness behavior.
    The Chinese journal of physiology, 2007, Apr-30, Volume: 50, Issue:2

    Topics: Adaptation, Psychological; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Depression; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Electric Stimulation; Helplessness, Learned; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride

2007
Experimental change on dopaminergic neurons in striatum of Parkinson disease rats.
    Histology and histopathology, 2007, Volume: 22, Issue:10

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Male; Motor Activity; Neurons; Oxidopamine; Parkinson Disease, Secondary; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Stereotypic Movement Disorder; Substantia Nigra; Up-Regulation

2007
Apomorphine-induced neurodegeneration in Mongolian gerbil hippocampus.
    Schizophrenia research, 2007, Volume: 95, Issue:1-3

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine; Gerbillinae; Hippocampus; Humans; Microscopy, Electron, Scanning; Nerve Degeneration; Neurons; Schizophrenia

2007
Unilateral implantation of dopamine-loaded biodegradable hydrogel in the striatum attenuates motor abnormalities in the 6-hydroxydopamine model of hemi-parkinsonism.
    Behavioural brain research, 2007, Nov-22, Volume: 184, Issue:1

    Topics: Absorbable Implants; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Delivery Systems; Drug Interactions; Functional Laterality; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Stereotyped Behavior; Time Factors; Tyrosine 3-Monooxygenase

2007
Identification of genetic and epigenetic variations in a rat model for neurodevelopmental disorders.
    Behavior genetics, 2007, Volume: 37, Issue:5

    Topics: Animals; Apomorphine; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 9; Disease Models, Animal; DNA Primers; Gene Rearrangement; Genetic Predisposition to Disease; Genetic Variation; Humans; Membrane Proteins; Mental Disorders; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Rats; Rats, Wistar; Schizophrenia

2007
Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in-vivo muPET imaging ([11C] raclopride) and in-vitro ([3H] spiperone) autoradiography.
    Synapse (New York, N.Y.), 2008, Volume: 62, Issue:1

    Topics: Age Factors; Animals; Apomorphine; Appetite Regulation; Autoradiography; Brain; Disease Models, Animal; Dopamine; Dopamine Agonists; Eating; Food Deprivation; In Vitro Techniques; Male; Motor Activity; Obesity; Positron-Emission Tomography; Raclopride; Rats; Rats, Zucker; Receptors, Dopamine D2; Receptors, Leptin; Spiperone; Tritium

2008
Low doses of apomorphine transiently reduce locomotor activity in MPTP-treated mice.
    Neuroscience letters, 2007, Nov-27, Volume: 428, Issue:2-3

    Topics: Animals; Apomorphine; Brain; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neural Inhibition; Parkinsonian Disorders

2007
Effects of chronic renal failure on the expression of connexin 43 in the rat's corpus cavernosum.
    Asian journal of andrology, 2008, Volume: 10, Issue:2

    Topics: Animals; Apomorphine; Blotting, Western; Connexin 43; Disease Models, Animal; Erectile Dysfunction; Gene Expression; Kidney Failure, Chronic; Male; Penile Erection; Penis; Rats; Rats, Sprague-Dawley

2008
Generation of a alpha-synuclein-based rat model of Parkinson's disease.
    Neurobiology of disease, 2008, Volume: 30, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; alpha-Synuclein; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Gene Expression Regulation; Gene Products, tat; Genetic Vectors; Green Fluorescent Proteins; Male; Motor Activity; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2008
Hemiparkinsonian rats rotate toward the side with the weaker dopaminergic neurotransmission.
    Behavioural brain research, 2008, Jun-03, Volume: 189, Issue:2

    Topics: Analysis of Variance; Animals; Apomorphine; Brain Damage, Chronic; Disease Models, Animal; Dopamine; Dopamine Agonists; Functional Laterality; Locomotion; Male; Motor Activity; MPTP Poisoning; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Rotation; Severity of Illness Index; Statistics, Nonparametric; Substantia Nigra

2008
Lack of robust protective effect of quercetin in two types of 6-hydroxydopamine-induced parkinsonian models in rats and dopaminergic cell cultures.
    Brain research, 2008, Apr-08, Volume: 1203

    Topics: Amphetamine; Animals; Antioxidants; Apomorphine; Behavior, Animal; Cell Line, Tumor; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Male; Motor Activity; Neuroblastoma; Oxidopamine; Parkinson Disease; Quercetin; Rats; Rats, Wistar; Substantia Nigra; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase

2008
Role for serotonin in the antidepressant-like effect of a flavonoid extract of Xiaobuxin-Tang.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:4

    Topics: Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Feeding Behavior; Fenclonine; Flavonoids; Humans; Hypothermia; Male; Mice; Mice, Inbred ICR; Motor Activity; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Serotonin; Stress, Physiological; Yohimbine

2008
Glycogen synthase kinase-3beta heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: negative results.
    Behavioural pharmacology, 2008, Volume: 19, Issue:3

    Topics: Animals; Apomorphine; Autopsy; Behavior, Animal; Brain; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium Compounds; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Phenotype; Reflex, Startle; Schizophrenia; Stereotyped Behavior; Swimming

2008
[Establishment of a rat model of diabetic erectile dysfunction].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2008, Volume: 28, Issue:4

    Topics: Animals; Apomorphine; Diabetes Mellitus, Experimental; Disease Models, Animal; Erectile Dysfunction; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin

2008
Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia.
    Psychopharmacology, 1980, Volume: 69, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain; Chlorpromazine; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Mouth Diseases; Movement Disorders; Occipital Lobe; Rats; Substance Withdrawal Syndrome

1980
[Effect of psychotropic drugs on the central dopamine metabolism (example: neuroleptics)].
    Arzneimittel-Forschung, 1981, Volume: Suppl 27

    Topics: Adenylyl Cyclases; Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Brain; Catalepsy; Cats; Conditioning, Classical; Disease Models, Animal; Dogs; Dopamine; Dopamine Antagonists; Humans; In Vitro Techniques; Rats; Receptors, Dopamine; Vomiting

1981
[Hypersensitivity to apomorphine in rats treated with neuroleptics: a model of tardive dyskinesia].
    Revista medica de Chile, 1982, Volume: 110, Issue:4

    Topics: Animals; Antipsychotic Agents; Apomorphine; Disease Models, Animal; Drug Hypersensitivity; Drug Interactions; Dyskinesia, Drug-Induced; Female; Rats; Rats, Inbred Strains

1982
Animal models of tardive dyskinesias.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Disease Models, Animal; Dyskinesia, Drug-Induced; Epidemiologic Methods; Guinea Pigs; Haloperidol; Humans; Time Factors

1983
Behavioural and biochemical alterations following haloperidol treatment and withdrawal: the animal model of tardive dyskinesia reexamined.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:2-3

    Topics: Animals; Apomorphine; Behavior, Animal; Brain; Disease Models, Animal; Dopamine; Glutamate Decarboxylase; Haloperidol; Humans; Male; Motor Activity; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase

1983
Molindone compared to haloperidol in a guinea-pig model of tardive dyskinesia.
    Neuropharmacology, 1984, Volume: 23, Issue:10

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Guinea Pigs; Haloperidol; Humans; Indoles; Male; Molindone; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Stereotyped Behavior

1984
N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) affects locomotor activity without producing a nigrostriatal lesion in the rat.
    Neuroscience letters, 1984, Jul-27, Volume: 48, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Apomorphine; Corpus Striatum; Depression, Chemical; Disease Models, Animal; Male; Motor Activity; Neural Pathways; Parkinson Disease; Pyridines; Rats; Rats, Inbred Strains; Substantia Nigra

1984
Dopamine inhibitory and excitatory systems in tardive dyskinesias.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Animals; Apomorphine; Disease Models, Animal; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; Hydroxydopamines; Male; Nucleus Accumbens; Oxidopamine; Piribedil; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride

1983
Characterization of the rat mutant dystonic (dt): a new animal model of dystonia musculorum deformans.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1984, Volume: 4, Issue:8

    Topics: Aging; Animals; Apomorphine; Brain Chemistry; Disease Models, Animal; Dopamine; Dystonia Musculorum Deformans; Haloperidol; Motor Activity; Mutation; Norepinephrine; Pedigree; Rats; Rats, Mutant Strains

1984
Oral tardive dyskinesia in the rat.
    Acta odontologica Scandinavica, 1983, Volume: 41, Issue:6

    Topics: Animals; Apomorphine; Bruxism; Dental Occlusion, Traumatic; Disease Models, Animal; Dyskinesia, Drug-Induced; Haloperidol; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Time Factors

1983
LSD-potentiated apomorphine hypermotility: a model for differentiating antipsychotic drugs.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:1

    Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Disease Models, Animal; Drug Antagonism; Haloperidol; Humans; Hyperkinesis; Lysergic Acid Diethylamide; Male; Motor Activity; Rats; Rats, Inbred Strains; Sulpiride

1983
An evaluation of the young dopamine-lesioned rat as an animal model for minimal brain dysfunction (MBD).
    Psychopharmacology, 1980, Volume: 67, Issue:2

    Topics: Animals; Apomorphine; Attention; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Dextroamphetamine; Disease Models, Animal; Dopamine; Female; Humans; Hydroxydopamines; Male; Motor Activity; Rats; Time Factors

1980
Effects of d-amphetamine and apomorphine in a new animal model of petit mal epilepsy.
    Psychopharmacology, 1980, Volume: 69, Issue:3

    Topics: Animals; Apomorphine; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy, Absence; Habituation, Psychophysiologic; Male; Phenoxybenzamine; Photic Stimulation; Pimozide; Rats

1980
Phencyclidine-induced stereotype in rats: effects of methadone, apomorphine, and naloxone.
    Psychopharmacology, 1981, Volume: 75, Issue:1

    Topics: Animals; Apomorphine; Brain Chemistry; Disease Models, Animal; Humans; Male; Methadone; Motor Activity; Naloxone; Phencyclidine; Psychoses, Substance-Induced; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors

1981
MK-771 antagonizes the enhanced response to apomorphine in rats treated chronically with haloperidol - implications for tardive dyskinesia.
    Neuroscience letters, 1982, Dec-31, Volume: 34, Issue:3

    Topics: Animals; Apomorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Thiazolidines; Thyrotropin-Releasing Hormone

1982
A new animal model for Tourette syndrome.
    Advances in neurology, 1982, Volume: 35

    Topics: Animals; Apomorphine; Dextroamphetamine; Disease Models, Animal; Haloperidol; Humans; Male; Nitriles; Rats; Rats, Inbred Strains; Rodent Diseases; Stereotyped Behavior; Tourette Syndrome

1982
Hormonal interference in experimental models of depression.
    Advances in biochemical psychopharmacology, 1982, Volume: 32

    Topics: Animals; Apomorphine; Behavior, Animal; Depressive Disorder; Disease Models, Animal; Haloperidol; Humans; Motor Activity; Muscle Tonus; Prolactin; Receptors, Dopamine

1982
A mechanographic method for measurement of muscle tone in the conscious rat. The calf muscle stretch response in reserpine-induced rigidity.
    Journal of neuroscience methods, 1982, Volume: 6, Issue:1-2

    Topics: Animals; Apomorphine; Biomechanical Phenomena; Disease Models, Animal; Haloperidol; Male; Muscle Contraction; Muscle Rigidity; Muscle Tonus; Neurophysiology; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Reflex, Stretch; Reserpine

1982
[Hallucinogen caused motility disorders in rats as potential psychosis relevant animal model].
    Sammlung zwangloser Abhandlungen aus dem Gebiete der Psychiatrie und Neurologie, 1982, Volume: 50

    Topics: Animals; Apomorphine; Brain; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Hallucinogens; Humans; Lysergic Acid Diethylamide; Methysergide; Motor Activity; Psychoses, Substance-Induced; Rats; Receptors, Dopamine; Receptors, Serotonin; Serotonin

1982
Correlation between daily dosage of chlorpromazine and subsequent supersensitivity.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Membranes; Stereotyped Behavior

1980
Antagonism of dopamine supersensitivity by estrogen: neurochemical studies in an animal model of tardive dyskinesia.
    Biological psychiatry, 1981, Volume: 16, Issue:4

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Estradiol; Female; Haloperidol; Humans; Rats; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome

1981
The behavior of APO-SUS rats in animal models with construct validity for schizophrenia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:11

    Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Exploratory Behavior; Male; Mastication; Neural Inhibition; Rats; Rats, Wistar; Reaction Time; Reflex, Startle; Schizophrenic Psychology; Stereotyped Behavior; Taste

1995
Behavioral involvement of central dopamine D1 and D2 receptors in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned parkinsonian cynomolgus monkeys.
    Japanese journal of pharmacology, 1995, Volume: 67, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Macaca fascicularis; Parkinson Disease, Secondary; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride; Time Factors

1995
Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine.
    Neuroscience, 1995, Volume: 67, Issue:3

    Topics: Animals; Apomorphine; Autoradiography; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mazindol; Neural Pathways; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors

1995
Effects of complete and partial lesions of the dopaminergic mesotelencephalic system on skilled forelimb use in the rat.
    Neuroscience, 1995, Volume: 67, Issue:4

    Topics: Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine; Forelimb; Parkinson Disease; Rats; Rats, Inbred Strains; Rotation

1995
Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:5 Pt 2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Apomorphine; Brain Tissue Transplantation; Carbidopa; Dextroamphetamine; Disease Models, Animal; Dopamine; Dopamine Agonists; Ergolines; Female; Fetal Tissue Transplantation; Forelimb; Functional Laterality; Levodopa; Motor Activity; Movement Disorders; Norepinephrine; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Transplantation, Heterotopic

1995
Asymmetrical motor behavior in rats with unilateral striatal excitotoxic lesions as revealed by the elevated body swing test.
    Brain research, 1995, Apr-03, Volume: 676, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Functional Laterality; Huntington Disease; Male; Motor Activity; Neurotoxins; Nitro Compounds; Propionates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Time Factors

1995
Dose- and duration-dependent tolerance to rotational effects of apomorphine in a rat model of Parkinsonism.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:1

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Dyskinesia, Drug-Induced; Male; Parkinson Disease; Rats; Rats, Sprague-Dawley

1995
Nerve growth factor released by transgenic astrocytes enhances the function of adrenal chromaffin cell grafts in a rat model of Parkinson's disease.
    Brain research, 1994, Sep-26, Volume: 658, Issue:1-2

    Topics: Adrenal Medulla; Animals; Animals, Genetically Modified; Apomorphine; Astrocytes; Cells, Cultured; Disease Models, Animal; Male; Motor Activity; Neostriatum; Nerve Growth Factors; Parkinson Disease; Rats; Recombinant Proteins; Rotation; Transplantation, Heterotopic

1994
Susceptibility to adjuvant arthritis: relative importance of adrenal activity and bacterial flora.
    Clinical and experimental immunology, 1994, Volume: 97, Issue:1

    Topics: Adrenal Glands; Animals; Antigens, Bacterial; Apomorphine; Arthritis, Experimental; Bacteria; Corticosterone; Disease Models, Animal; Female; Germ-Free Life; Hypothalamo-Hypophyseal System; Interleukin-1; Neuroimmunomodulation; Pituitary-Adrenal System; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Wistar; Species Specificity

1994
The role of D1 and D2 receptors in the heightened locomotion induced by direct and indirect dopamine agonists in rats with hippocampal damage: an animal analogue of schizophrenia.
    Behavioural brain research, 1993, Jun-30, Volume: 55, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Arousal; Brain Mapping; Dextroamphetamine; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Ergolines; Hippocampus; Male; Motor Activity; Quinpirole; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Stereotyped Behavior

1993
Effect of chronic antidepressant treatment on responses to apomorphine in selectively bred rat strains.
    Brain research bulletin, 1993, Volume: 32, Issue:5

    Topics: 1-Naphthylamine; Animals; Apomorphine; Body Temperature Regulation; Breeding; Depressive Disorder; Desipramine; Disease Models, Animal; Male; Motor Activity; Parasympathetic Nervous System; Rats; Sertraline; Time Factors

1993
The effect of peripheral inositol injection on rat motor activity models of depression.
    Israel journal of medical sciences, 1993, Volume: 29, Issue:9

    Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Depression; Disease Models, Animal; Drug Synergism; Glucose; Inositol; Lithium; Male; Motor Activity; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Stereotyped Behavior

1993
Classification of drug-induced behaviors using a multi-layer feed-forward neural network.
    Computer methods and programs in biomedicine, 1993, Volume: 40, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Bias; Central Nervous System; Disease Models, Animal; Evaluation Studies as Topic; Fourier Analysis; Grooming; Male; Microcomputers; Monitoring, Physiologic; Motor Activity; Neural Networks, Computer; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Signal Processing, Computer-Assisted; Smell; Tongue; Videotape Recording

1993
Electrical sensitization of the meso-limbic dopaminergic system in rats: a pathogenetic model for schizophrenia.
    Brain research, 1993, Aug-13, Volume: 619, Issue:1-2

    Topics: Amphetamine; Animals; Apomorphine; Benzazepines; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Electric Stimulation; Electroencephalography; Habituation, Psychophysiologic; Haloperidol; Limbic System; Male; Models, Neurological; Motor Activity; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D1; Salicylamides; Schizophrenia; Seizures; Stereotyped Behavior; Tegmentum Mesencephali; Time Factors

1993
Pica in rats is analogous to emesis: an animal model in emesis research.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:4

    Topics: Animals; Antiemetics; Apomorphine; Cisplatin; Copper; Copper Sulfate; Disease Models, Animal; Domperidone; Dose-Response Relationship, Drug; Food; Kaolin; Male; Ondansetron; Pica; Rats; Rats, Wistar; Vomiting

1993
Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophrenia.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:3

    Topics: Animals; Apomorphine; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; Habituation, Psychophysiologic; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenic Psychology

1993
Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson's disease.
    Brain research, 1995, Sep-11, Volume: 691, Issue:1-2

    Topics: Amphetamine; Animals; Apomorphine; Astrocytes; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Genetic Vectors; Humans; Male; Nerve Fibers; Nerve Growth Factors; Nerve Tissue Proteins; Parkinson Disease, Secondary; Rats; Rats, Inbred F344; Retroviridae; Rotation; Transduction, Genetic

1995
The effect of transcranial magnetic stimulation of rat brain on behavioral models of depression.
    Brain research, 1995, Nov-13, Volume: 699, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Electric Stimulation; Electroconvulsive Therapy; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Transcranial Magnetic Stimulation

1995
Selective adenosine A2A receptor/dopamine D2 receptor interactions in animal models of schizophrenia.
    European journal of pharmacology, 1996, Jan-11, Volume: 295, Issue:2-3

    Topics: Animals; Apomorphine; Behavior, Animal; Benzazepines; Catalepsy; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Schizophrenia

1996
Transplantation of human fetal striatum into a rodent model of Huntington's disease ameliorates locomotor deficits.
    Neuroscience research, 1996, Volume: 24, Issue:4

    Topics: Acetylcholinesterase; Animals; Antiparkinson Agents; Apomorphine; Brain Tissue Transplantation; Coloring Agents; Disease Models, Animal; Fetal Tissue Transplantation; Histocytochemistry; Humans; Huntington Disease; Locomotion; Male; NADPH Dehydrogenase; Neostriatum; Phenothiazines; Rats; Rats, Sprague-Dawley; Rotation

1996
Somatic delivery of catecholamines in the striatum attenuate parkinsonian symptoms and widen the therapeutic window of oral sinemet in rats.
    Experimental neurology, 1997, Volume: 145, Issue:1

    Topics: Administration, Oral; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Carbidopa; Cell Transplantation; Disease Models, Animal; Dopamine; Drug Combinations; Drug Synergism; Levodopa; Male; Movement Disorders; Neostriatum; Parkinson Disease, Secondary; PC12 Cells; Rats; Rats, Sprague-Dawley; Rotation

1997
The effect of nigral implantation on sensitization to dopamine agonists in 6-hydroxydopamine-lesioned rats.
    Neuroscience, 1997, Volume: 79, Issue:4

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Locomotion; Male; Oxidopamine; Pregnancy; Rats; Rats, Sprague-Dawley; Substantia Nigra

1997
Prefrontal cortical and hippocampal modulation of dopamine-mediated effects.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: Aging; Amphetamine; Animals; Animals, Newborn; Apomorphine; Disease Models, Animal; Dopamine; Haloperidol; Hippocampus; Humans; Motor Activity; Prefrontal Cortex; Rats; Reflex, Startle; Schizophrenia; Sexual Maturation; Stereotyped Behavior; Stress, Psychological; Synapses; Synaptic Transmission

1998
An animal model of copulatory disorder induced by social stress in male mice: effects of apomorphine and L-dopa.
    Psychopharmacology, 1997, Volume: 133, Issue:3

    Topics: Aggression; Animals; Apomorphine; Copulation; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Dose-Response Relationship, Drug; Levodopa; Male; Mice; Mice, Inbred ICR; Sexual Behavior, Animal; Sexual Dysfunction, Physiological; Social Environment; Stress, Psychological

1997
An automated rotarod method for quantitative drug-free evaluation of overall motor deficits in rat models of parkinsonism.
    Brain research. Brain research protocols, 1997, Dec-01, Volume: 2, Issue:1

    Topics: Animals; Apomorphine; Automation; Brain; Disease Models, Animal; Equipment Design; Female; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reference Values; Reproducibility of Results

1997
Adenoviral vector-mediated GDNF gene therapy in a rodent lesion model of late stage Parkinson's disease.
    Brain research, 1997, Nov-28, Volume: 777, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenoviridae; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agonists; Enzyme-Linked Immunosorbent Assay; Female; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Humans; Nerve Growth Factors; Nerve Regeneration; Nerve Tissue Proteins; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics

1997
Fixed-ratio discrimination training as replacement therapy in Parkinson's disease: studies in a 6-hydroxydopamine-treated rat model.
    Brain research, 1998, Jan-05, Volume: 780, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Conditioning, Operant; Corpus Striatum; Discrimination Learning; Disease Models, Animal; Dopamine; Dopamine Agents; Male; Motor Activity; Neurotoxins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Reinforcement Schedule

1998
Cross-sensitization between footshock stress and apomorphine on self-injurious behavior and neostriatal catecholamines in a rat model of Lesch-Nyhan syndrome.
    Brain research, 1998, Feb-02, Volume: 783, Issue:1

    Topics: Animals; Animals, Newborn; Apomorphine; Catecholamines; Disease Models, Animal; Dopamine Agonists; Electroshock; Injections, Intraventricular; Lesch-Nyhan Syndrome; Male; Neostriatum; Neurotoxins; Oxidopamine; Rats; Rats, Sprague-Dawley; Self-Injurious Behavior; Stress, Physiological

1998
Topographical organization of opioid peptide precursor gene expression following repeated apomorphine treatment in the 6-hydroxydopamine-lesioned rat.
    Experimental neurology, 1998, Volume: 150, Issue:2

    Topics: Animals; Apomorphine; Brain; Caudate Nucleus; Disease Models, Animal; Enkephalins; Gene Expression Regulation; In Situ Hybridization; Male; Motor Activity; Nucleus Accumbens; Organ Specificity; Oxidopamine; Parkinson Disease; Protein Precursors; Putamen; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors

1998
Asymmetry of sympathetic activity in a rat model of Parkinson's disease induced by 6-hydroxydopamine: haemodynamic, electrocardiographic and biochemical changes.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1998, Volume: 197, Issue:5

    Topics: Animals; Apomorphine; Behavior, Animal; Catecholamines; Disease Models, Animal; Electrocardiography; Functional Laterality; Hemodynamics; Immunohistochemistry; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Substantia Nigra; Sympathetic Nervous System; Tyrosine 3-Monooxygenase

1998
Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions.
    Annals of neurology, 1998, Volume: 43, Issue:5

    Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Carrier Proteins; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Iodine Radioisotopes; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Fibers; Nerve Tissue Proteins; Neuropeptides; Neurotransmitter Agents; Oxidopamine; Parkinson Disease, Secondary; Prosencephalon; Radioimmunoassay; Rats; Rats, Wistar; Substantia Nigra; Sulpiride; Sympatholytics; Tyrosine 3-Monooxygenase; Ventral Tegmental Area; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

1998
Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jun-01, Volume: 18, Issue:11

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Dependovirus; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Gene Expression Regulation, Enzymologic; Gene Transfer Techniques; GTP Cyclohydrolase; Humans; Levodopa; Male; Microdialysis; Neurons; Parkinson Disease, Secondary; Rats; Rats, Inbred F344; Recombinant Proteins; Rotation; Tyrosine 3-Monooxygenase

1998
In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTPcyclohydrolase I with tyrosine hydroxylase.
    Experimental neurology, 1998, Volume: 151, Issue:2

    Topics: 3T3 Cells; Animals; Antioxidants; Antiparkinson Agents; Apomorphine; Behavior, Animal; Biopterins; Corpus Striatum; Dihydroxyphenylalanine; Disease Models, Animal; Fibroblasts; Gene Expression Regulation, Enzymologic; Genetic Therapy; Gliosarcoma; GTP Cyclohydrolase; Humans; Levodopa; Male; Mice; Microdialysis; Parkinson Disease, Secondary; Rats; Rats, Inbred F344; Recombinant Fusion Proteins; Retroviridae; Transformation, Genetic; Transgenes; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

1998
Effects of dopaminergic drugs, occlusal disharmonies, and chronic stress on non-functional masticatory activity in the rat, assessed by incisal attrition.
    Journal of dental research, 1998, Volume: 77, Issue:6

    Topics: Analysis of Variance; Animals; Apomorphine; Bruxism; Cocaine; Dental Occlusion, Traumatic; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Incisor; Male; Masticatory Muscles; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Stress, Physiological; Tooth Attrition

1998
The overall rod performance test in the MPTP-treated-mouse model of Parkinsonism.
    Journal of neuroscience methods, 1998, Sep-01, Volume: 83, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Parkinson Disease, Secondary; Tyrosine 3-Monooxygenase

1998
Excitotoxic lesions of the rat medial prefrontal cortex. Effects on abnormal behaviors associated with neonatal hippocampal damage.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 19, Issue:6

    Topics: Amphetamine; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Hippocampus; In Situ Hybridization; Motor Activity; Prefrontal Cortex; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stereotyped Behavior

1998
Neuroprotective effects of the alpha2-adrenoceptor antagonists, (+)-efaroxan and (+/-)-idazoxan, against quinolinic acid-induced lesions of the rat striatum.
    Experimental neurology, 1998, Volume: 154, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Behavior, Animal; Benzofurans; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Enzyme Activation; Huntington Disease; Idazoxan; Imidazoles; Male; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2

1998
Embryonic striatal grafts restore neuronal activity of the globus pallidus in a rodent model of Huntington's disease.
    Neuroscience, 1999, Volume: 88, Issue:2

    Topics: Action Potentials; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Electron Transport Complex IV; Electrophysiology; Fetal Tissue Transplantation; Globus Pallidus; Huntington Disease; Male; Neurons; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Rotation

1999
Biochemical and anatomical characterization of forepaw adjusting steps in rat models of Parkinson's disease: studies on medial forebrain bundle and striatal lesions.
    Neuroscience, 1999, Volume: 88, Issue:2

    Topics: Adaptation, Physiological; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Female; Forelimb; Gait; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase

1999
Disruption of latent inhibition in rats with postnatal hippocampal lesions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:6

    Topics: Anesthesia; Animals; Apomorphine; Cognition Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Agonists; Hippocampus; Ibotenic Acid; Learning; Motor Activity; Neural Inhibition; Rats; Rats, Sprague-Dawley; Schizophrenic Psychology

1999
Apomorphine protects against MPTP-induced neurotoxicity in mice.
    Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Tyrosine 3-Monooxygenase

1999
Long-term doxycycline-controlled expression of human tyrosine hydroxylase after direct adenovirus-mediated gene transfer to a rat model of Parkinson's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Oct-12, Volume: 96, Issue:21

    Topics: Adenoviridae; Animals; Anti-Bacterial Agents; Antiparkinson Agents; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Doxycycline; Female; Gene Expression Regulation; Gene Transfer Techniques; Humans; Immunohistochemistry; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase

1999
A new video/computer method to measure the amount of overall movement in experimental animals (two-dimensional object-difference method).
    Journal of neuroscience methods, 1999, Sep-15, Volume: 91, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Callithrix; Computer Storage Devices; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Image Interpretation, Computer-Assisted; Movement; Parkinson Disease; Time Factors; Video Recording

1999
The role of D2 and D3 dopamine receptors in the mediation of emesis in Cryptotis parva (the least shrew).
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:11-12

    Topics: Analysis of Variance; Animals; Apomorphine; Benzopyrans; Brain Chemistry; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Indans; Male; Oxazines; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Shrews; Species Specificity; Sulpiride; Tetrahydronaphthalenes; Vomiting

1999
Effects of chronic haloperidol and clozapine on vacuous chewing and dopamine-mediated jaw movements in rats: evaluation of a revised animal model of tardive dyskinesia.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:11-12

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Clozapine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dyskinesia, Drug-Induced; Haloperidol; Jaw; Male; Mastication; Quinpirole; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Serotonin Antagonists

1999
Effect of acute L-Dopa pretreatment on apomorphine-induced rotational behavior in a rat model of Parkinson's disease.
    Experimental neurology, 2000, Volume: 161, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Carbidopa; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred F344; Rotation; Substantia Nigra; Sympatholytics

2000
Who believes in "communication"? The Norman Cousins Lecture, 1999.
    Brain, behavior, and immunity, 2000, Volume: 14, Issue:1

    Topics: Adaptation, Psychological; Aggression; Animals; Apomorphine; Arthritis, Rheumatoid; Autoimmune Diseases; Behavior; Behavior, Animal; beta-Adrenergic Receptor Kinases; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Disease Susceptibility; Encephalomyelitis, Autoimmune, Experimental; Humans; Hypothalamo-Hypophyseal System; Inflammation; Motor Activity; Multiple Sclerosis; Neuroimmunomodulation; Neurosecretory Systems; Pituitary-Adrenal System; Psychoneuroimmunology; Psychotherapy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta-2; Schizophrenia; Stress, Physiological; Th1 Cells; Th2 Cells; Trichinellosis

2000
The effect of intrastriatal single injection of GDNF on the nigrostriatal dopaminergic system in hemiparkinsonian rats: behavioral and histological studies using two different dosages.
    Neuroscience research, 2000, Volume: 36, Issue:4

    Topics: Animals; Apomorphine; Axons; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Functional Laterality; Glial Cell Line-Derived Neurotrophic Factor; Immunohistochemistry; Movement; Neostriatum; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase; Weight Loss

2000
Multi-site partitioned delivery of human tyrosine hydroxylase gene with phenotypic recovery in Parkinsonian rats.
    Neuroreport, 2000, Apr-27, Volume: 11, Issue:6

    Topics: Adenoviridae; Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Cell Count; Corpus Striatum; Disease Models, Animal; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Phenotype; Rats; Rats, Inbred F344; Recovery of Function; Treatment Outcome; Tyrosine 3-Monooxygenase

2000
Effects of oligonucleotide antisense to dopamine D(1A) receptor messenger RNA in a rodent model of levodopa-induced dyskinesia.
    Neuroscience, 2000, Volume: 98, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Autoradiography; Behavior, Animal; Cocaine; Denervation; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Gene Expression; Levodopa; Male; Oligonucleotides, Antisense; Oxidopamine; Phenotype; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Rotation; Substantia Nigra; Sympatholytics; Tritium

2000
The antidepressive-like effect of oxcarbazepine: possible role of dopaminergic neurotransmission.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2000, Volume: 10, Issue:4

    Topics: Animals; Antidepressive Agents; Apomorphine; Carbamazepine; Catalepsy; Disease Models, Animal; Dopamine Antagonists; Haloperidol; Male; Neurotransmitter Agents; Oxcarbazepine; Rats; Rats, Wistar; Receptors, Dopamine; Stereotypic Movement Disorder; Swimming

2000
Failure of neuroprotection by embryonic striatal grafts in a double lesion rat model of striatonigral degeneration (multiple system atrophy).
    Experimental neurology, 2000, Volume: 164, Issue:1

    Topics: Animals; Apomorphine; Autoradiography; Binding, Competitive; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Fetal Tissue Transplantation; Male; Membrane Proteins; Motor Activity; Multiple System Atrophy; Nerve Tissue Proteins; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Striatonigral Degeneration; Treatment Failure

2000
Xenotransplantation of microencapsulated bovine chromaffin cells into hemiparkinsonian monkeys.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2000, Volume: 28, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Medulla; Animals; Antiparkinson Agents; Apomorphine; Capsules; Cattle; Chromaffin Cells; Disease Models, Animal; Dopamine; Female; Homovanillic Acid; Macaca mulatta; Microdialysis; Neostriatum; Parkinsonian Disorders; Stereotyped Behavior; Transplantation, Heterologous

2000
Birth insult alters dopamine-mediated behavior in a precocial species, the guinea pig. Implications for schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:6

    Topics: Age Factors; Amphetamine; Animals; Apomorphine; Asphyxia Neonatorum; Behavior, Animal; Cesarean Section; Disease Models, Animal; Dopamine; Female; Guinea Pigs; Humans; Hypoxia, Brain; Infant, Newborn; Male; Motor Activity; Neural Inhibition; Reflex, Startle; Schizophrenia

2000
Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Male; Melatonin; Mitochondria; Motor Activity; NAD; Neuroprotective Agents; Oxidative Phosphorylation; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Substantia Nigra

2001
IGF-I and bFGF improve dopamine neuron survival and behavioral outcome in parkinsonian rats receiving cultured human fetal tissue strands.
    Experimental neurology, 2001, Volume: 168, Issue:1

    Topics: Abortion, Induced; Animals; Apomorphine; Brain; Brain Tissue Transplantation; Cell Survival; Cells, Cultured; Disease Models, Animal; Dopamine; Female; Fetal Tissue Transplantation; Fibroblast Growth Factor 2; Homovanillic Acid; Humans; Insulin-Like Growth Factor I; Male; Methamphetamine; Motor Activity; Neurons; Oxidopamine; Parkinsonian Disorders; Pregnancy; Rats; Rats, Sprague-Dawley; Rotation; Transplantation, Heterologous; Tyrosine 3-Monooxygenase

2001
Hyperactivity and impaired response habituation in hyperdopaminergic mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Feb-13, Volume: 98, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Apomorphine; Attention Deficit Disorder with Hyperactivity; Benzazepines; Carrier Proteins; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Female; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Activity; Nerve Tissue Proteins; Psychomotor Agitation; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2

2001
Neuroprotective effect of vitamin E on the early model of Parkinson's disease in rat: behavioral and histochemical evidence.
    Brain research, 2001, Feb-16, Volume: 892, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Atrophy; Axonal Transport; Corpus Striatum; Disease Models, Animal; Male; Motor Activity; Neurons; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Vitamin E; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate

2001
No functional effects of embryonic neuronal grafts on motor deficits in a 3-nitropropionic acid rat model of advanced striatonigral degeneration (multiple system atrophy).
    Neuroscience, 2001, Volume: 102, Issue:3

    Topics: Animals; Apomorphine; Brain Tissue Transplantation; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Fetal Tissue Transplantation; Humans; Male; Mesencephalon; Motor Activity; Multiple System Atrophy; Neurons; Neurotoxins; Nitro Compounds; Propionates; Psychomotor Performance; Rats; Rats, Wistar; Substantia Nigra; Time Factors

2001
Microencapsulated bovine chromaffin cell xenografts into hemiparkinsonian rats: a drug-induced rotational behavior and histological changes analysis.
    Artificial organs, 2001, Volume: 25, Issue:2

    Topics: Animals; Apomorphine; Capsules; Cattle; Cell Survival; Chromaffin Cells; Disease Models, Animal; Female; Microscopy, Fluorescence; Parkinson Disease; Parkinson Disease, Secondary; Psychomotor Disorders; Rats; Rats, Sprague-Dawley; Rotation; Sensitivity and Specificity; Transplantation, Heterologous

2001
Involvement of GABAergic neurotransmission in the neurobiology of the apomorphine-induced aggressive behavior paradigm, a model of psychotic behavior in rats.
    Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:8

    Topics: Aggression; Animals; Apomorphine; Baclofen; Behavior, Animal; Disease Models, Animal; GABA Agonists; Isoxazoles; Male; Neurotransmitter Agents; Psychotic Disorders; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission

2000
Attenuation of paraquat-induced dopaminergic toxicity on the substantia nigra by (-)-deprenyl in vivo.
    Toxicology and applied pharmacology, 2001, Apr-01, Volume: 172, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Herbicides; Male; Neuroprotective Agents; Paraquat; Rats; Rats, Wistar; Selegiline; Stereotyped Behavior; Substantia Nigra

2001
Effects of R- and S-apomorphine on MPTP-induced nigro-striatal dopamine neuronal loss.
    Journal of neurochemistry, 2001, Volume: 77, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Binding, Competitive; Catecholamines; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Glutathione; Glutathione Disulfide; Immunohistochemistry; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Neuroprotective Agents; Parkinson Disease, Secondary; Stereoisomerism; Substantia Nigra; Tyrosine 3-Monooxygenase

2001
Resolution of stroke deficits following contralateral grafts of conditionally immortal neuroepithelial stem cells.
    Stroke, 2001, Volume: 32, Issue:4

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Cell Differentiation; Cell Line, Transformed; Disease Models, Animal; Dopamine Agents; Epithelial Cells; Graft Survival; Infarction, Middle Cerebral Artery; Male; Maze Learning; Mice; Motor Activity; Neurons; Rats; Rats, Wistar; Reaction Time; Recovery of Function; Stem Cell Transplantation; Stem Cells; Stroke; Temperature; Treatment Outcome

2001
Entopeduncular lesions facilitate and thalamic lesions depress spontaneous and drug-evoked motor behavior in the hemiparkinsonian rat.
    Synapse (New York, N.Y.), 2001, Jun-01, Volume: 40, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Denervation; Disease Models, Animal; Dopamine Agonists; Dyskinesia, Drug-Induced; Entopeduncular Nucleus; Male; Motor Cortex; Neural Inhibition; Neural Pathways; Neurosurgical Procedures; Oxidopamine; Parkinsonian Disorders; Rats; Thalamus; Ventral Thalamic Nuclei

2001
The role of neurochemical mechanisms of ventromedial hypothalamus in various models of anxiety in rats.
    Bulletin of experimental biology and medicine, 2001, Volume: 131, Issue:1

    Topics: Adrenergic Agents; Animals; Anxiety; Apomorphine; Avoidance Learning; Disease Models, Animal; Dopamine; Dopamine Agents; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus, Middle; Male; Memantine; Microinjections; Neurotransmitter Agents; Phenylephrine; Picrotoxin; Rats; Serotonin; Sulpiride; Yohimbine

2001
Forced limb-use effects on the behavioral and neurochemical effects of 6-hydroxydopamine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jun-15, Volume: 21, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Body Temperature; Casts, Surgical; Corpus Striatum; Disease Models, Animal; Dopamine; Forelimb; Homovanillic Acid; Immobilization; Male; Medial Forebrain Bundle; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Neural Pathways; Neurons; Neuropeptides; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Long-Evans; Substantia Nigra; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2001
The frissonnant mutant mouse, a model of dopamino-sensitive, inherited motor syndrome.
    Neurobiology of disease, 2001, Volume: 8, Issue:3

    Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Electromyography; Female; Genes, Recessive; Immunohistochemistry; Indoles; Levodopa; Male; Memory Disorders; Mice; Mice, Inbred C3H; Mice, Neurologic Mutants; Motor Activity; Neurons; Parkinson Disease, Secondary; Postural Balance; Selegiline; Tyrosine 3-Monooxygenase

2001
Electrophysiological and pharmacological characteristics of two types of spike-wave discharges in WAG/Rij rats.
    Brain research, 2001, Aug-17, Volume: 911, Issue:1

    Topics: Action Potentials; Animals; Apomorphine; Biological Clocks; Cerebral Cortex; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Electroencephalography; Epilepsy, Absence; Haloperidol; Neurons; Rats; Rats, Mutant Strains

2001
In vivo extracellular recording of striatal neurons in the awake rat following unilateral 6-hydroxydopamine lesions.
    Experimental neurology, 2001, Volume: 171, Issue:1

    Topics: Action Potentials; Anesthesia; Animals; Apomorphine; Chloral Hydrate; Corpus Striatum; Disease Models, Animal; Dopamine; Electrodes, Implanted; Male; Microelectrodes; Motor Activity; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred F344; Receptors, Dopamine D2; Wakefulness

2001
Functional effect of adeno-associated virus mediated gene transfer of aromatic L-amino acid decarboxylase into the striatum of 6-OHDA-lesioned rats.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2001, Volume: 4, Issue:4

    Topics: Animals; Apomorphine; Aromatic-L-Amino-Acid Decarboxylases; Dependovirus; Disease Models, Animal; Dopamine; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Levodopa; Neostriatum; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotation; Transduction, Genetic

2001
Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease.
    Experimental neurology, 2002, Volume: 173, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glial Cell Line-Derived Neurotrophic Factor; Hedgehog Proteins; Humans; Microinjections; Motor Activity; Myristic Acid; Nerve Growth Factors; Nerve Tissue Proteins; Organ Specificity; Oxidopamine; Parkinson Disease, Secondary; Peptide Fragments; Rats; Trans-Activators; Tyrosine 3-Monooxygenase

2002
Effects of short- and long-acting dopamine agonists on sensitized dopaminergic neurotransmission in rats with unilateral 6-OHDA lesions.
    Life sciences, 2002, Jan-18, Volume: 70, Issue:9

    Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Cabergoline; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Drug Antagonism; Ergolines; Levodopa; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Synaptic Transmission

2002
Striatal AMPA receptor binding is unaltered in the MPTP-lesioned macaque model of Parkinson's disease and dyskinesia.
    Experimental neurology, 2002, Volume: 174, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alanine; Animals; Apomorphine; Autoradiography; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Excitatory Amino Acid Agonists; Female; Ligands; Macaca mulatta; Male; Organ Specificity; Parkinson Disease, Secondary; Pyrimidines; Radioligand Assay; Receptors, AMPA

2002
The rate of intravenous cocaine administration determines susceptibility to sensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-15, Volume: 22, Issue:8

    Topics: Animals; Apomorphine; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Intravenous; Male; Medial Forebrain Bundle; Microinjections; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Time Factors

2002
Development of a rat model of sexual performance anxiety: effect of behavioural and pharmacological hyperadrenergic stimulation on APO-induced erections.
    International journal of impotence research, 2002, Volume: 14, Issue:2

    Topics: Animals; Anxiety Disorders; Apomorphine; Blood Pressure; Disease Models, Animal; Erectile Dysfunction; Heart Rate; Hemodynamics; Male; Methoxamine; Penile Erection; Rats; Rats, Wistar; Sexual Behavior, Animal; Stress, Psychological; Sympathetic Nervous System

2002
Somatostatin modulates the behavioral effects of dopamine receptor activation in parkinsonian rats.
    Neuroscience, 2002, Volume: 112, Issue:2

    Topics: Animals; Apomorphine; Autoradiography; Behavior, Animal; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Administration Routes; Male; Medial Forebrain Bundle; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Somatostatin

2002
Adeno-associated viral delivery of GDNF promotes recovery of dopaminergic phenotype following a unilateral 6-hydroxydopamine lesion.
    Cell transplantation, 2002, Volume: 11, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Cell Line; Corpus Striatum; Dependovirus; Disease Models, Animal; Dopamine; Genetic Therapy; Glial Cell Line-Derived Neurotrophic Factor; Humans; Male; Medial Forebrain Bundle; Motor Activity; Nerve Growth Factors; Oxidopamine; Parkinsonian Disorders; Phenotype; Rats; Rats, Inbred F344; Substantia Nigra; Tyrosine 3-Monooxygenase

2002
Kainic acid lesions of the striatum dissociate amphetamine and apomorphine stereotypy: similarities to Huntingdon's chorea.
    Science (New York, N.Y.), 1978, Jul-28, Volume: 201, Issue:4353

    Topics: Animals; Apomorphine; Behavior; Choline O-Acetyltransferase; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Glutamate Decarboxylase; Humans; Huntington Disease; Kainic Acid; Male; Nucleus Accumbens; Pyrrolidines; Rats; Stereotyped Behavior; Tyrosine 3-Monooxygenase

1978
Kainic acid lesions of the striatum: behavioural sequalae similar to Huntington's chorea.
    Brain research, 1978, Oct-27, Volume: 155, Issue:2

    Topics: Animals; Apomorphine; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamate Decarboxylase; Habituation, Psychophysiologic; Humans; Huntington Disease; Kainic Acid; Male; Motor Activity; Neurons; Nucleus Accumbens; Pyrrolidines; Rats; Stereotyped Behavior; Tyrosine 3-Monooxygenase

1978
Differential enhancement of locomotor activity by dopamine agonists following chronic neuroleptic treatment: an animal model of tardive dyskinesia.
    European journal of pharmacology, 1979, Apr-01, Volume: 55, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Ergolines; Male; Motor Activity; Rats; Time Factors

1979
Experimental torticollis in the monkey produced by unilateral 6-hydroxy-dopamine brain lesions.
    Brain research, 1978, Jun-30, Volume: 149, Issue:2

    Topics: Animals; Apomorphine; Callitrichinae; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Dominance, Cerebral; Dose-Response Relationship, Drug; Haplorhini; Humans; Hydroxydopamines; Hypothalamus; Male; Movement; Receptors, Dopamine; Stereotyped Behavior; Tegmentum Mesencephali; Torticollis

1978
Experimental torticollis in the marmoset produced by injection of 6-hydroxydopamine into the ascending nigrostriatal pathway.
    Experimental neurology, 1979, Volume: 63, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Benserazide; Callitrichinae; Disease Models, Animal; Drug Therapy, Combination; Haloperidol; Haplorhini; Hydroxydopamines; Hypothalamus; Levodopa; Locus Coeruleus; Male; Torticollis

1979
Sedative effects of apomorphine in an animal model of Huntington's disease.
    Archives of neurology, 1979, Volume: 36, Issue:6

    Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Humans; Huntington Disease; Kainic Acid; Male; Motor Activity; Rats; Receptors, Dopamine; Stereotyped Behavior

1979
Acute dystonia as an idiosyncratic response to neuroleptics in baboons.
    Brain : a journal of neurology, 1977, Volume: 100, Issue:2

    Topics: 5-Hydroxytryptophan; Acute Disease; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Haloperidol; Haplorhini; Humans; Levodopa; Movement Disorders; Papio; Parasympatholytics; Physostigmine; Pimozide; Receptors, Dopamine; Reserpine; Syndrome; Tranquilizing Agents

1977
Clinical and experimental studies of phenytoin-induced hyperkinesias.
    Journal of neural transmission, 1979, Volume: 45, Issue:4

    Topics: Aged; Animals; Apomorphine; Basal Ganglia; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Drug Synergism; Dyskinesia, Drug-Induced; Female; Guinea Pigs; Haloperidol; Humans; Hyperkinesis; Male; Middle Aged; Phenytoin; Stereotyped Behavior

1979
A dopaminergic basis for the effects of amphetamine on a mouse "preadolescent hyperkinetic" model.
    Life sciences, 1977, Jul-01, Volume: 21, Issue:1

    Topics: Adolescent; Aging; Amphetamine; Animals; Apomorphine; Clonidine; Disease Models, Animal; Humans; Hyperkinesis; Mice; Mice, Inbred Strains; Myoclonus; Sleep

1977
Choline chloride in animal models of tardive dyskinesia.
    Life sciences, 1978, May-15, Volume: 22, Issue:19

    Topics: Animals; Apomorphine; Choline; Disease Models, Animal; Dyskinesia, Drug-Induced; Haloperidol; Humans; Male; Rats; Receptors, Dopamine; Stereotyped Behavior; Time Factors

1978
Some neuropharmacological aspects of schizophrenia: a short review.
    Irish journal of medical science, 1978, Volume: 147 Suppl 1

    Topics: Amphetamines; Animals; Apomorphine; Disease Models, Animal; Hallucinogens; Humans; Psychoses, Substance-Induced; Rats; Schizophrenia, Paranoid

1978
The effect of lithium on an animal model of tardive dyskinesia.
    Progress in neuro-psychopharmacology, 1977, Volume: 1, Issue:1-2

    Topics: Animals; Apomorphine; Dextroamphetamine; Disease Models, Animal; Dyskinesia, Drug-Induced; Guinea Pigs; Haloperidol; Humans; Lithium; Male; Receptors, Dopamine; Stereotyped Behavior

1977
Postsynaptic supersensitivity and kindling: further evidence of similarities.
    The American journal of drug and alcohol abuse, 1978, Volume: 5, Issue:2

    Topics: Animals; Apomorphine; Behavior; Cocaine; Dextroamphetamine; Disease Models, Animal; Humans; Injections, Intraperitoneal; Rats; Receptors, Dopamine; Stereotyped Behavior; Time Factors

1978
Levodopa-induced dopamine receptor hypersensitivity.
    Transactions of the American Neurological Association, 1977, Volume: 102

    Topics: Animals; Apomorphine; Dextroamphetamine; Disease Models, Animal; Dyskinesia, Drug-Induced; Humans; Levodopa; Mice; Receptors, Dopamine; Stereotyped Behavior

1977
Dopaminergic agonists in animal models of parkinsonism.
    Advances in neurology, 1975, Volume: 9

    Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Cats; Disease Models, Animal; Haplorhini; Levodopa; Parkinson Disease, Secondary; Piribedil; Rats; Reserpine; Tyrosine

1975
Effect of intracaudate drug injections on the striatal syndrome in reserpinized cats.
    Neuropharmacology, 1977, Volume: 16, Issue:3

    Topics: Animals; Apomorphine; Atropine; Cats; Caudate Nucleus; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Dopamine; Male; Neuromuscular Diseases; Parkinson Disease; Reserpine; Syndrome

1977
Amphetamine induced turning behavior as an index of stroke in the Mongolian gerbil.
    Experientia, 1977, May-15, Volume: 33, Issue:5

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Carotid Arteries; Cerebrovascular Disorders; Disease Models, Animal; Gerbillinae; Time Factors

1977
Effect of local application of apomorphine to the corpus striatum and to the nucleus accumbens on the reserpine-induced rigidity in rats.
    Brain research, 1977, Sep-16, Volume: 133, Issue:2

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Muscle Rigidity; Nucleus Accumbens; Rats; Reserpine; Septal Nuclei

1977
Reinstatement of eating by dopamine agonists in aphagic dopamine denervated rats.
    Physiology & behavior, 1976, Volume: 16, Issue:3

    Topics: Animals; Apomorphine; Denervation; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Humans; Hydroxydopamines; Hypothalamus; Levodopa; Male; Motor Activity; Nerve Degeneration; Parkinson Disease; Piperazines; Rats; Receptors, Dopamine; Stereotyped Behavior; Stimulation, Chemical

1976
Amphetamine-induced dopaminergic hypersensitivity in guinea pigs. Implications in psychosis and human movement disorders.
    Archives of general psychiatry, 1975, Volume: 32, Issue:6

    Topics: Amphetamine; Animals; Apomorphine; Behavior; Behavior, Animal; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Levodopa; Movement Disorders; Psychoses, Substance-Induced; Reaction Time; Receptors, Drug; Schizophrenia; Stereotyped Behavior; Substance-Related Disorders

1975
Actions of dopaminergic agonists on motor function.
    Advances in neurology, 1975, Volume: 9

    Topics: Amantadine; Animals; Apomorphine; Behavior; Dextroamphetamine; Disease Models, Animal; Dopamine Antagonists; Humans; Hyperkinesis; Levodopa; Methylphenidate; Motor Activity; Movement Disorders; Phenethylamines; Piribedil; Rats; Stereotyped Behavior; Tyrosine

1975
Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine.
    Psychopharmacologia, 1975, Volume: 41, Issue:2

    Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzazepines; Dibenzoxazepines; Disease Models, Animal; Dopamine; Drug Tolerance; Female; Haloperidol; Homovanillic Acid; Humans; Loxapine; Male; Movement Disorders; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome

1975
Supersensitivity to d-amphetamine- and apomorphine-induced stereotyped behavior induced by chronic d-amphetamine administration.
    Journal of the neurological sciences, 1975, Volume: 25, Issue:3

    Topics: Animals; Apomorphine; Behavior; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Dopamine; Humans; Levodopa; Male; Mice; Movement Disorders; Parkinson Disease; Receptors, Drug; Stereotyped Behavior; Time Factors

1975
Functional analysis of brain dopamine systems in a genetic mouse model of Lesch-Nyhan syndrome.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamines; Animals; Apomorphine; Brain Chemistry; Disease Models, Animal; Dopamine; Female; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Male; Methylphenidate; Mice; Mice, Inbred C57BL; Motor Activity; Nalidixic Acid; Naphthyridines

1992
Basic fibroblast growth factor ameliorates rotational behavior of substantia nigral-transplanted rats with lesions of the dopaminergic nigrostriatal neurons.
    Japanese journal of pharmacology, 1992, Volume: 59, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Female; Fibroblast Growth Factor 2; Gliosis; Immunohistochemistry; Neural Pathways; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Rotation; Substantia Nigra

1992
[The antiemetic activity of buspirone].
    Likars'ka sprava, 1992, Issue:9

    Topics: Animals; Antiemetics; Apomorphine; Buspirone; Cisplatin; Columbidae; Disease Models, Animal; Drug Evaluation, Preclinical; Vomiting

1992
Intrastriatal transplantation of cross-species fetal striatal cells reduces abnormal movements in a primate model of Huntington disease.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, May-01, Volume: 89, Issue:9

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Fetus; Huntington Disease; Immunosuppression Therapy; Papio; Regression Analysis; Transplantation, Heterologous

1992
Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior.
    Brain research, 1991, Jul-12, Volume: 553, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Axons; Denervation; Disease Models, Animal; Female; Motor Activity; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred Strains; Rotation; Substantia Nigra; Tyrosine 3-Monooxygenase

1991
Lesioning of the striatum reverses motor asymmetry in the 6-hydroxydopamine rodent model of parkinsonism.
    Journal of neural transplantation & plasticity, 1991, Volume: 2, Issue:2

    Topics: Adrenal Medulla; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Graft Survival; Immunohistochemistry; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Rotation; Stereotaxic Techniques; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical; Tyrosine 3-Monooxygenase

1991
Baseline and apomorphine-induced extracellular levels of nigral substance P are increased in an animal model of Parkinson's disease.
    European journal of pharmacology, 1990, Jul-17, Volume: 182, Issue:3

    Topics: Animals; Apomorphine; Dialysis; Disease Models, Animal; Dopamine; Ganglia, Sympathetic; Hydroxydopamines; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra

1990
Melatonin modulates apomorphine-induced rotational behaviour.
    Experientia, 1991, May-15, Volume: 47, Issue:5

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Huntington Disease; Hydroxydopamines; Male; Melatonin; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains

1991
Positive and negative interactions in the behavioural expression of D1 and D2 receptor stimulation in a model of Parkinsonism: role of priming.
    Neuroscience, 1991, Volume: 42, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Benzazepines; Disease Models, Animal; Dopamine Antagonists; Hydroxydopamines; Male; Oxidopamine; Parkinson Disease; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Stereotyped Behavior

1991
Effects of apomorphine, a dopamine receptor agonist, on ocular refraction and axial elongation in a primate model of myopia.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:5

    Topics: Administration, Topical; Animals; Anterior Chamber; Apomorphine; Disease Models, Animal; Eye; Intraocular Pressure; Macaca mulatta; Myopia; Refraction, Ocular

1991
Mechanisms of action of adrenal medulla grafts: the possible role of peripheral and central dopamine systems.
    Progress in brain research, 1990, Volume: 82

    Topics: Adrenal Medulla; Adrenalectomy; Amphetamine; Animals; Apomorphine; Blood-Brain Barrier; Cerebral Ventricles; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Hydroxydopamines; Male; Models, Biological; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred Strains; Transplantation, Heterotopic

1990
A functional assessment of embryonic dopaminergic grafts in the marmoset.
    Progress in brain research, 1990, Volume: 82

    Topics: Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Callitrichinae; Corpus Striatum; Disease Models, Animal; Dopamine; Fetal Tissue Transplantation; Functional Laterality; Hydroxydopamines; Mesencephalon; Motor Activity; Motor Skills; Oxidopamine; Parkinson Disease

1990
A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon.
    Experimental neurology, 1990, Volume: 108, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Diseases; Caudate Nucleus; Disease Models, Animal; Dystonia; Female; Huntington Disease; Ibotenic Acid; Male; Motor Activity; Movement; Papio; Putamen

1990
Apomorphine-induced dyskinesias after excitotoxic caudate-putamen lesions and the effects of neural transplantation in non-human primates.
    Progress in brain research, 1990, Volume: 82

    Topics: Animals; Apomorphine; Brain Tissue Transplantation; Caudate Nucleus; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Fetal Tissue Transplantation; Huntington Disease; Ibotenic Acid; Male; Papio; Putamen; Rats; Species Specificity; Transplantation, Heterologous

1990
Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease.
    Brain research, 1990, Oct-01, Volume: 528, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Body Weight; Corpus Striatum; Disease Models, Animal; Dopamine; Hydrazines; Levodopa; Male; Methyltyrosines; Mice; Mice, Inbred C57BL; Motor Activity; Parkinson Disease, Secondary; Receptors, Dopamine; Stereotyped Behavior

1990
Preliminary report on adrenal medullary grafting and cografting with sural nerve in the treatment of hemiparkinson monkeys.
    Progress in brain research, 1990, Volume: 82

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenal Medulla; Animals; Apomorphine; Behavior, Animal; Carbidopa; Caudate Nucleus; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Levodopa; Macaca mulatta; Motor Activity; Parkinson Disease; Sural Nerve; Transplantation, Heterotopic

1990
Is experimental catalepsy properly measured?
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:4

    Topics: Adrenal Glands; Animals; Apomorphine; Catalepsy; Disease Models, Animal; Drug Interactions; Haloperidol; Male; Rats; Rats, Inbred Strains

1990
An encapsulated dopamine-releasing polymer alleviates experimental parkinsonism in rats.
    Experimental neurology, 1989, Volume: 105, Issue:3

    Topics: Acrylic Resins; Animals; Apomorphine; Brain; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Implants; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Polyvinyls; Rats; Rats, Inbred Strains

1989
A 6-hydroxydopamine-induced selective parkinsonian rat model.
    Brain research, 1989, Aug-14, Volume: 494, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Disease Models, Animal; Functional Laterality; Hydroxydopamines; Limbic System; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereotyped Behavior

1989
Brain iron: a lesson from animal models.
    The American journal of clinical nutrition, 1989, Volume: 50, Issue:3 Suppl

    Topics: Amphetamine; Anemia, Hypochromic; Animals; Antipsychotic Agents; Apomorphine; beta-Endorphin; Body Temperature Regulation; Brain; Disease Models, Animal; Dopamine; Iron; Iron Deficiencies; Learning; Motor Activity; Pain; Rats; Receptors, Dopamine; Sensory Thresholds

1989
[The placebo effect: between mind and brain].
    Medicina clinica, 1989, Feb-18, Volume: 92, Issue:6

    Topics: Animals; Apomorphine; Brain; Conditioning, Psychological; Disease Models, Animal; Humans; Parkinson Disease; Placebos

1989
The pathophysiology of tardive dyskinesia.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:4 Pt 2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Chlorpromazine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Fluphenazine; Guinea Pigs; Haloperidol; Humans; Receptors, Dopamine; Stereotyped Behavior; Thioridazine; Time Factors

1985
Performance deficit induced by low doses of dopamine agonists in rats. Toward a model for approaching the neurobiology of negative schizophrenic symptomatology?
    Biological psychiatry, 1986, Volume: 21, Issue:1

    Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Disease Models, Animal; Male; Phenothiazines; Pimozide; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reinforcement Schedule; Reinforcement, Psychology; Schizophrenia; Schizophrenic Psychology; Sulpiride

1986
Conditioning of the early behavioral response to apomorphine in the rotational model of Parkinson's disease.
    European journal of pharmacology, 1988, Jan-19, Volume: 145, Issue:3

    Topics: Animals; Apomorphine; Conditioning, Psychological; Disease Models, Animal; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains

1988
Changes in dopamine autoreceptor sensitivity in an animal model of depression.
    Psychopharmacology, 1988, Volume: 94, Issue:4

    Topics: Animals; Apomorphine; Body Weight; Depression; Desipramine; Disease Models, Animal; Eating; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stress, Physiological

1988
Behavioral and neurochemical evaluation of a transgenic mouse model of Lesch-Nyhan syndrome.
    Journal of the neurological sciences, 1988, Volume: 86, Issue:2-3

    Topics: Animals; Apomorphine; Avoidance Learning; Biogenic Amines; Brain Chemistry; Disease Models, Animal; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Mice; Mice, Transgenic; Motor Activity; Mutation; Reference Values; Reflex; Swimming

1988
L-5-HTP-induced myoclonic jumping behavior in guinea pigs: an update.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Bromocriptine; Clonazepam; Disease Models, Animal; Guinea Pigs; Haloperidol; Lisuride; Morphine; Myoclonus; Naloxone; Scopolamine; Tremorine

1986
Hemiparkinsonism in monkeys after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Life sciences, 1986, Jul-07, Volume: 39, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Brain; Brain Chemistry; Carbidopa; Carotid Artery, Internal; Disease Models, Animal; Dominance, Cerebral; Dopamine; Homovanillic Acid; Injections, Intra-Arterial; Levodopa; Macaca fascicularis; Movement; Neurons; Parkinson Disease, Secondary; Pyridines

1986
Terguride, a mixed dopamine agonist-antagonist, in animal models of Parkinson's disease.
    Neurology, 1987, Volume: 37, Issue:4

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Disease Models, Animal; Ergolines; Levodopa; Lisuride; Male; Motor Activity; Parkinson Disease; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior

1987
Influence of changes in brain monoamine metabolism on behaviour of herpes simplex-infected mice.
    Journal of the neurological sciences, 1974, Volume: 22, Issue:3

    Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Brain; Clonidine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfides; Dopamine; Dopamine beta-Hydroxylase; Fenclonine; Herpes Simplex; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyltyrosines; Mice; Motor Activity; Norepinephrine; Phenoxybenzamine; Pimozide; Receptors, Adrenergic; Serotonin; Tyrosine 3-Monooxygenase; Vaccinia; Virus Cultivation

1974
6-Hydroxydopamine lesions of olfactory tubercles and caudate nuclei: effect on amphetamine-induced stereotyped behavior in rats.
    Brain research, 1974, Dec-20, Volume: 82, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Behavior; Behavior, Animal; Brain Chemistry; Brain Mapping; Caudate Nucleus; Disease Models, Animal; Dopamine; Histocytochemistry; Humans; Hydroxydopamines; Limbic System; Male; Microscopy, Fluorescence; Nerve Degeneration; Neural Pathways; Olfactory Bulb; Psychoses, Substance-Induced; Rats; Stereotyped Behavior; Synaptic Transmission

1974
Biochemical aspects of experimentally induced parkinsonism.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: 5-Hydroxytryptophan; Amines; Amino Acids; Animals; Antiparkinson Agents; Apomorphine; Basal Ganglia; Biogenic Amines; Brain; Carboxy-Lyases; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Dopamine beta-Hydroxylase; Haplorhini; Humans; Monoamine Oxidase Inhibitors; Parkinson Disease; Rats; Tyrosine 3-Monooxygenase; Visual Cortex

1972
Behavioral, physiological, and neurochemical changes after 6-hydroxydopamine-induced degeneration of the nigro-striatal dopamine neurons.
    Advances in neurology, 1974, Volume: 5

    Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Drinking Behavior; Electric Stimulation; Electromyography; Feeding and Eating Disorders; Feeding Behavior; Humans; Hydroxydopamines; Levodopa; Motor Neurons; Muscle Contraction; Nerve Degeneration; Neural Pathways; Parkinson Disease; Parkinson Disease, Secondary; Perceptual Disorders; Rats; Reflex, Stretch; Substantia Nigra

1974
An experimental model of tardive dyskinesia.
    Journal of neural transmission, 1972, Volume: 33, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Movement Disorders; Stereotyped Behavior

1972
Dopamine receptor site sensitivity in hyperthyroid guinea pigs: a possible model of hyperthyroid chorea.
    Journal of neural transmission, 1973, Volume: 34, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Chorea; Corpus Striatum; Disease Models, Animal; Dopamine; Guinea Pigs; Humans; Hyperthyroidism; Male; Receptors, Drug; Stereotyped Behavior; Thyroxine

1973
Bait-shyness acquisition is impaired by VMH lesions that produce obesity.
    Journal of comparative and physiological psychology, 1972, Volume: 79, Issue:2

    Topics: Animal Nutritional Physiological Phenomena; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Conditioning, Psychological; Cues; Disease Models, Animal; Drinking Behavior; Eating; Extinction, Psychological; Feeding Behavior; Female; Hypothalamus; Injections, Intraperitoneal; Obesity; Rats; Saccharin; Taste

1972
[Dependence of the anti-inflammatory effect of reserpine, caffeine and apomorphine on adrenal medulla in rats].
    Casopis lekaru ceskych, 1972, Sep-15, Volume: 111, Issue:38

    Topics: Adrenal Medulla; Animals; Anti-Inflammatory Agents; Apomorphine; Caffeine; Catecholamines; Disease Models, Animal; Edema; Rats; Reserpine

1972
The neuroleptics. 3. Pharmacology. Introduction.
    Modern problems of pharmacopsychiatry, 1970, Volume: 5

    Topics: Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior; Behavior, Animal; Blepharoptosis; Brain; Catalepsy; Chemical Phenomena; Chemistry; Conditioning, Psychological; Disease Models, Animal; Dopamine Antagonists; Humans; Psychotic Disorders; Self Stimulation; Tranquilizing Agents

1970
Observations on the pathogenesis of Reye's syndrome.
    Southern medical journal, 1971, Volume: 64, Issue:8

    Topics: Adipose Tissue; Animals; Apomorphine; Brain Diseases; Child; Child, Preschool; Disease Models, Animal; Dogs; Fatty Liver; Female; Hepatitis; Humans; Hypoglycemia; Infant; Kidney Diseases; Leukocytes; Lipid Metabolism; Male; Organ Size; Virus Diseases; Vomiting

1971