apnea has been researched along with Tachyarrhythmia in 41 studies
Apnea: A transient absence of spontaneous respiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "• Caffeine therapy for treatment of apnea of prematurity has been well established over the past few years." | 9.20 | High versus low-dose caffeine for apnea of prematurity: a randomized controlled trial. ( Abdel-Hady, H; Mohammed, S; Nasef, N; Nour, I; Shabaan, AE; Shouman, B, 2015) |
| "The purpose of our prospective randomized study was to compare the efficacy of theophylline ethylenediamine and caffeine sodium citrate in the treatment of idiopathic apnea in premature infants." | 9.05 | Comparative efficacy of theophylline and caffeine in the treatment of idiopathic apnea in premature infants. ( Brouard, C; de Gamarra, E; Flouvat, B; Moriette, G; Murat, I; Pajot, N; Relier, JP; Walti, H, 1985) |
| "The aim of this study was to investigate the disturbances of the acid-base balance and electrolyte disorders in healthy individuals in the greatest passive apnea (prior to apnea and prior to first inhalation)." | 7.72 | The effect of intense passive apnea in the acid-base balance and electrolytes. ( Mavromatidis, K; Peiou, M; Roudenko, I; Sotirakopoulos, N; Tsitsios, T; Tsjliiras, T, 2003) |
| " Significant complications occurred in 4 of 38 patients, including atrial fibrillation, accelerated ventricular tachycardia, apnea, and 1 minute of asystole." | 7.69 | Therapeutic and diagnostic utility of adenosine during tachycardia evaluation in children. ( Crosson, JE; Dunnigan, A; Etheridge, SP; Hesslein, PS; Milstein, S, 1994) |
| "Apnea, bradycardia, and neuromuscular hyperirritability have been associated with magnesium (Mg) deficiency in young human infants and weanling animals." | 7.67 | Magnesium therapy in premature neonates with apnea neonatorum. ( Caddell, JL, 1988) |
| " This study was conducted to determine the cardiac effects of five successive apnea periods separated by 1 min of free ventilation (FV)." | 7.66 | Sex differences in cardiac responses to successive apnea periods. ( Monod, H; Sanchez, J; Sebert, P, 1982) |
| "To the well known methods for prevention of neonatal apnea like stimulation, CPAP, and mechanical ventilation the treatment with theophylline has been added recently." | 7.66 | [Prevention of neonatal apnea with theophylline (author's transl)]. ( Frisch, H; Irnberger, E; Müller, W, 1978) |
| "The administration of 160 mg of propranolol during pregnancy, labor, and delivery was associated with profound hypoglycemia and respiratory depression in a newborn infant." | 7.65 | Propranolol therapy during pregnancy, labor, and delivery: evidence for transplacental drug transfer and impaired neonatal drug disposition. ( Cottrill, CM; Gettes, L; McAllister, RG; Noonan, JA, 1977) |
| "• Caffeine therapy for treatment of apnea of prematurity has been well established over the past few years." | 5.20 | High versus low-dose caffeine for apnea of prematurity: a randomized controlled trial. ( Abdel-Hady, H; Mohammed, S; Nasef, N; Nour, I; Shabaan, AE; Shouman, B, 2015) |
| "4%) or apnea (11 of 78, 14." | 5.19 | A phase I, dose-escalation trial evaluating the safety and efficacy of emulsified isoflurane in healthy human volunteers. ( Huang, H; Li, R; Liao, T; Liu, J; Yi, X; Zhang, W, 2014) |
| "The purpose of our prospective randomized study was to compare the efficacy of theophylline ethylenediamine and caffeine sodium citrate in the treatment of idiopathic apnea in premature infants." | 5.05 | Comparative efficacy of theophylline and caffeine in the treatment of idiopathic apnea in premature infants. ( Brouard, C; de Gamarra, E; Flouvat, B; Moriette, G; Murat, I; Pajot, N; Relier, JP; Walti, H, 1985) |
| " When examining only PVSCs without NAS, only 4% (3/75) of studies obtained for apnea and 2." | 3.83 | Diagnostic yield of continuous video electroencephalography for paroxysmal vital sign changes in pediatric patients. ( Dang, LT; Shellhaas, RA, 2016) |
| " Swallowing tachycardia was observed during the SWS-associated apnea period, but not during the imagination period." | 3.79 | Sympathetic skin responses in adult humans during sequential swallowing. ( Arıcı, Ş; Çe, P; Çelebisoy, M; Ertekin, C; Gürgör, N; İncesu, TK; Özdemirkıran, T; Seçil, Y; Tokuçoğlu, F, 2013) |
| "The aim of this study was to investigate the disturbances of the acid-base balance and electrolyte disorders in healthy individuals in the greatest passive apnea (prior to apnea and prior to first inhalation)." | 3.72 | The effect of intense passive apnea in the acid-base balance and electrolytes. ( Mavromatidis, K; Peiou, M; Roudenko, I; Sotirakopoulos, N; Tsitsios, T; Tsjliiras, T, 2003) |
| "The monitor system detected 7/51 central apneas, 6/260 desaturations and 7/18 tachycardias." | 3.72 | [Reliability of home monitoring with event-recording compared with polysomnography in infants]. ( de Nardi, S; Erler, T; Gruntzke, A; Paditz, E, 2003) |
| " We performed spectral analysis of RR and MSNA variability during each of the following interventions: 1) controlled breathing, 2) maximal end-expiratory apnea, 3) isocapnic voluntary hyperventilation, and 4) hypercapnia-induced hyperventilation." | 3.71 | Importance of ventilation in modulating interaction between sympathetic drive and cardiovascular variability. ( Degaute, JP; Malliani, A; Montano, N; Narkiewicz, K; Pagani, M; Somers, VK; Van De Borne, P, 2001) |
| " Significant complications occurred in 4 of 38 patients, including atrial fibrillation, accelerated ventricular tachycardia, apnea, and 1 minute of asystole." | 3.69 | Therapeutic and diagnostic utility of adenosine during tachycardia evaluation in children. ( Crosson, JE; Dunnigan, A; Etheridge, SP; Hesslein, PS; Milstein, S, 1994) |
| "After saline pretreatment, response to 5-HT consisted of immediate and brief apnea, bradycardia, and hypotension, followed by sustained tachypnea, tachycardia, pulmonary hypertension, and hypocapnic hypoxemia." | 3.69 | Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves. ( Amory, H; Desmecht, DJ; Lekeux, PM; Linden, AS, 1996) |
| "7%) more than half occurred during high amplitude fluctuations of the thoracic impedance signal and were relative to obstructive apnea or hypertonic vagal reactivity." | 3.68 | [Home cardio-respiratory monitoring with alarm record system in infants at risk of life-threatening events]. ( de Broca, A; Dorival, D; Faltaous, S; Kremp, O; Risbourg, B; Zenatti, I, 1992) |
| ", performing crawl movements with the legs continuously at a constant rhythm) with and without apnea (water temperature: 31 degrees C)." | 3.68 | Cardiac output and heart rate in man during simulated swimming while breath-holding. ( Honda, Y; Morikawa, T; Paulev, PE; Pokorski, M; Sakakibara, Y; Tanaka, Y, 1990) |
| "Apnea, bradycardia, and neuromuscular hyperirritability have been associated with magnesium (Mg) deficiency in young human infants and weanling animals." | 3.67 | Magnesium therapy in premature neonates with apnea neonatorum. ( Caddell, JL, 1988) |
| " Resuscitation was performed using open-chest heart massage, bretylium for ventricular tachycardia, and epinephrine with atropine for electromechanical dissociation and bradycardia." | 3.67 | Successful cardiovascular resuscitation after massive intravenous bupivacaine overdosage in anesthetized dogs. ( Kasten, GW; Martin, ST, 1985) |
| " This study was conducted to determine the cardiac effects of five successive apnea periods separated by 1 min of free ventilation (FV)." | 3.66 | Sex differences in cardiac responses to successive apnea periods. ( Monod, H; Sanchez, J; Sebert, P, 1982) |
| " The appearance of atactic gait and clonic tonic seizures were followed by loss of consciousness, apnea, supraventricular tachycardia, left bundle-branch block, and a prolonged Q-T interval." | 3.66 | Intoxication with ajmaline in an infant. ( Ben-Shachar, G; Kishon, Y, 1979) |
| "To the well known methods for prevention of neonatal apnea like stimulation, CPAP, and mechanical ventilation the treatment with theophylline has been added recently." | 3.66 | [Prevention of neonatal apnea with theophylline (author's transl)]. ( Frisch, H; Irnberger, E; Müller, W, 1978) |
| "The administration of 160 mg of propranolol during pregnancy, labor, and delivery was associated with profound hypoglycemia and respiratory depression in a newborn infant." | 3.65 | Propranolol therapy during pregnancy, labor, and delivery: evidence for transplacental drug transfer and impaired neonatal drug disposition. ( Cottrill, CM; Gettes, L; McAllister, RG; Noonan, JA, 1977) |
| " Our data suggest that epinephrine or phenylephrine added to bupivacaine may be more toxic to cardiorespiratory systems than plain bupivacaine or epinephrine alone or phenylephrine alone when injected intravenously in rats." | 1.28 | Epinephrine and phenylephrine increase cardiorespiratory toxicity of intravenously administered bupivacaine in rats. ( Holaday, DA; Kambam, JR; Kinney, WW; Matsuda, F; Wright, W, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (65.85) | 18.7374 |
| 1990's | 6 (14.63) | 18.2507 |
| 2000's | 3 (7.32) | 29.6817 |
| 2010's | 5 (12.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elmegaard, SL | 1 |
| McDonald, BI | 1 |
| Madsen, PT | 1 |
| Huang, H | 1 |
| Li, R | 1 |
| Liu, J | 1 |
| Zhang, W | 1 |
| Liao, T | 1 |
| Yi, X | 1 |
| Mohammed, S | 1 |
| Nour, I | 1 |
| Shabaan, AE | 1 |
| Shouman, B | 1 |
| Abdel-Hady, H | 1 |
| Nasef, N | 1 |
| Dang, LT | 1 |
| Shellhaas, RA | 1 |
| Arıcı, Ş | 1 |
| Gürgör, N | 1 |
| Seçil, Y | 1 |
| İncesu, TK | 1 |
| Özdemirkıran, T | 1 |
| Çe, P | 1 |
| Çelebisoy, M | 1 |
| Tokuçoğlu, F | 1 |
| Ertekin, C | 1 |
| Roudenko, I | 1 |
| Tsjliiras, T | 1 |
| Sotirakopoulos, N | 1 |
| Tsitsios, T | 1 |
| Peiou, M | 1 |
| Mavromatidis, K | 1 |
| de Nardi, S | 1 |
| Paditz, E | 1 |
| Erler, T | 1 |
| Gruntzke, A | 1 |
| SANTIBANEZ, G | 1 |
| SAAVEDRA, MA | 1 |
| MIDDLETON, S | 1 |
| CRAIG, AB | 1 |
| FU, SX | 1 |
| CHANG, SS | 1 |
| LI, YS | 1 |
| WANG, NC | 1 |
| GINSBURG, SJ | 1 |
| GERSTLEY, L | 1 |
| Sebert, P | 1 |
| Sanchez, J | 1 |
| Monod, H | 1 |
| Garmash, VIa | 1 |
| Selivanova, Gv | 1 |
| Crosson, JE | 1 |
| Etheridge, SP | 1 |
| Milstein, S | 1 |
| Hesslein, PS | 1 |
| Dunnigan, A | 1 |
| Linden, AS | 1 |
| Desmecht, DJ | 1 |
| Amory, H | 1 |
| Lekeux, PM | 1 |
| Todd, BS | 1 |
| Andrews, DC | 1 |
| Van De Borne, P | 1 |
| Montano, N | 1 |
| Narkiewicz, K | 1 |
| Degaute, JP | 1 |
| Malliani, A | 1 |
| Pagani, M | 1 |
| Somers, VK | 1 |
| Ben-Shachar, G | 1 |
| Kishon, Y | 1 |
| Eisenberg, W | 1 |
| Holzgraefe, E | 1 |
| Naim, M | 1 |
| Frisch, H | 1 |
| Müller, W | 1 |
| Irnberger, E | 1 |
| Hanna, JM | 1 |
| Strauss, RH | 1 |
| Itagaki, B | 1 |
| Kwon, WJ | 1 |
| Stanyon, R | 1 |
| Bindon, J | 1 |
| Hong, SK | 1 |
| Cottrill, CM | 1 |
| McAllister, RG | 1 |
| Gettes, L | 1 |
| Noonan, JA | 1 |
| de Broca, A | 1 |
| Zenatti, I | 1 |
| Dorival, D | 1 |
| Kremp, O | 1 |
| Faltaous, S | 1 |
| Risbourg, B | 1 |
| Kambam, JR | 1 |
| Kinney, WW | 1 |
| Matsuda, F | 1 |
| Wright, W | 1 |
| Holaday, DA | 1 |
| Paulev, PE | 1 |
| Pokorski, M | 1 |
| Honda, Y | 1 |
| Morikawa, T | 1 |
| Sakakibara, Y | 1 |
| Tanaka, Y | 1 |
| Caddell, JL | 1 |
| Gupta, PD | 1 |
| Singh, M | 1 |
| Kasten, GW | 1 |
| Martin, ST | 1 |
| Brouard, C | 1 |
| Moriette, G | 1 |
| Murat, I | 1 |
| Flouvat, B | 1 |
| Pajot, N | 1 |
| Walti, H | 1 |
| de Gamarra, E | 1 |
| Relier, JP | 1 |
| Sehhati, G | 1 |
| Frey, R | 1 |
| Mildner, R | 1 |
| Rendoing, J | 1 |
| Choisy, H | 1 |
| Pascalis, G | 1 |
| Bajolet, A | 1 |
| Gisselmann, A | 1 |
| Urbach, JR | 1 |
| Grauman, JJ | 1 |
| Straus, SH | 1 |
| Horgan, JH | 1 |
| Ford, GD | 1 |
| Proctor, JD | 1 |
| Wasserman, AJ | 1 |
| Crampton, RS | 1 |
| Oriscello, RG | 1 |
| Tabatabai, M | 1 |
| Jaszmann, L | 1 |
| Somers, K | 1 |
| Gunstone, RF | 1 |
| Patel, AK | 1 |
| D'Arbela, PG | 1 |
| Philbin, DM | 1 |
| Wang, RI | 1 |
| Hussar, AE | 1 |
| Pachter, M | 1 |
| Liu, CT | 1 |
| Hoff, HE | 1 |
| Huggins, RA | 1 |
| Wynands, JE | 1 |
| Fox, GS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| High Versus Low Dose Caffeine as Respiratory Stimulant in Preterm Infants[NCT04144712] | Phase 1 | 80 participants (Anticipated) | Interventional | 2019-04-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for apnea and Tachyarrhythmia
| Article | Year |
|---|---|
A phase I, dose-escalation trial evaluating the safety and efficacy of emulsified isoflurane in healthy human volunteers.
Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Apnea; Cohort Studies; Dose-Response Relati | 2014 |
High versus low-dose caffeine for apnea of prematurity: a randomized controlled trial.
Topics: Airway Extubation; Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Dose-Response Relat | 2015 |
Marijuana smoking and cold tolerance in man.
Topics: Adaptation, Physiological; Adult; Apnea; Body Temperature; Bradycardia; Cannabis; Clinical Trials as | 1976 |
Comparative efficacy of theophylline and caffeine in the treatment of idiopathic apnea in premature infants.
Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Tachycardia; Theophylline | 1985 |
37 other studies available for apnea and Tachyarrhythmia
| Article | Year |
|---|---|
Drivers of the dive response in trained harbour porpoises (
Topics: Animals; Apnea; Behavior, Animal; Bradycardia; Breath Holding; Diving; Female; Immersion; Phocoena; | 2019 |
Diagnostic yield of continuous video electroencephalography for paroxysmal vital sign changes in pediatric patients.
Topics: Adolescent; Apnea; Bradycardia; Child; Child, Preschool; Cohort Studies; Electroencephalography; Fem | 2016 |
Sympathetic skin responses in adult humans during sequential swallowing.
Topics: Adult; Aged; Aged, 80 and over; Apnea; Apocrine Glands; Arousal; Deglutition; Deglutition Disorders; | 2013 |
The effect of intense passive apnea in the acid-base balance and electrolytes.
Topics: Acid-Base Equilibrium; Adolescent; Adult; Apnea; Biomarkers; Calcium; Carbon Dioxide; Electrolytes; | 2003 |
[Reliability of home monitoring with event-recording compared with polysomnography in infants].
Topics: Age Factors; Apnea; Female; Gestational Age; Home Nursing; Humans; Hypoxia; Infant; Male; Monitoring | 2003 |
CARDIAC AND RESPIRATORY CONCOMITANTS IN CLASSICAL DEFENSIVE CONDITIONING IN CATS.
Topics: Apnea; Bradycardia; Cats; Conditioning, Classical; Dogs; Electricity; Electrocardiography; Heart; He | 1963 |
HEART RATE RESPONSES TO APNEIC UNDERWATER DIVING AND TO BREATH HOLDING IN MAN.
Topics: Apnea; Bradycardia; Breath Holding; Child; Diving; Heart Function Tests; Heart Rate; Humans; Male; T | 1963 |
[THE TOXICITY AND GENERAL PHARMACOLOGICAL ACTIONS OF SINOMENINE].
Topics: Alkaloids; Animals; Anura; Apnea; Appetite; Blood Cells; Blood Pressure; Dogs; Dyspnea; Gastrointest | 1963 |
FETAL TACHYCARDIA IN LABOR.
Topics: Apnea; Bradycardia; Female; Fetal Diseases; Fetal Heart; Humans; Infant, Newborn; Labor, Obstetric; | 1965 |
Sex differences in cardiac responses to successive apnea periods.
Topics: Adult; Apnea; Bradycardia; Female; Heart Rate; Humans; Male; Respiration; Sex Factors; Tachycardia; | 1982 |
[Treatment procedure in asthmatic states].
Topics: Apnea; Asthma; Critical Care; Cyanosis; Emergencies; Humans; Tachycardia | 1981 |
Therapeutic and diagnostic utility of adenosine during tachycardia evaluation in children.
Topics: Adenosine; Adolescent; Adult; Apnea; Arrhythmia, Sinus; Atrial Fibrillation; Atrial Function; Atriov | 1994 |
Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves.
Topics: Aging; Animals; Apnea; Atropine; Bradycardia; Cattle; Cattle Diseases; Cholinergic Agents; Ganglioni | 1996 |
The identification of peaks in physiological signals.
Topics: Algorithms; Apnea; Biometry; Child; Computers; Electrocardiography; Humans; Infant, Newborn; Models, | 1999 |
Importance of ventilation in modulating interaction between sympathetic drive and cardiovascular variability.
Topics: Adult; Apnea; Carbon Dioxide; Chemoreceptor Cells; Electrocardiography; Female; Heart Rate; Humans; | 2001 |
Intoxication with ajmaline in an infant.
Topics: Accidents, Home; Administration, Oral; Ajmaline; Apnea; Arrhythmias, Cardiac; Ataxia; Bundle-Branch | 1979 |
[Theophylline for prevention of apnea in premature infants (author's transl)].
Topics: Apnea; Birth Weight; Humans; Infant, Newborn; Infant, Premature, Diseases; Tachycardia; Theophylline | 1978 |
[Prevention of neonatal apnea with theophylline (author's transl)].
Topics: Apnea; Bradycardia; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Tachycardia; | 1978 |
Propranolol therapy during pregnancy, labor, and delivery: evidence for transplacental drug transfer and impaired neonatal drug disposition.
Topics: Adult; Apnea; Female; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Male; Matern | 1977 |
[Home cardio-respiratory monitoring with alarm record system in infants at risk of life-threatening events].
Topics: Apnea; Bradycardia; Cardiography, Impedance; Female; Heart Defects, Congenital; Heart Rate; Humans; | 1992 |
Epinephrine and phenylephrine increase cardiorespiratory toxicity of intravenously administered bupivacaine in rats.
Topics: Animals; Apnea; Bupivacaine; Drug Interactions; Epinephrine; Heart Rate; Injections, Intravenous; Ma | 1990 |
Cardiac output and heart rate in man during simulated swimming while breath-holding.
Topics: Adult; Apnea; Cardiac Output; Diving; Exercise; Heart Rate; Humans; Male; Middle Aged; Oxygen Consum | 1990 |
Magnesium therapy in premature neonates with apnea neonatorum.
Topics: Apnea; Birth Weight; Bradycardia; Drug Administration Schedule; Follow-Up Studies; Gestational Age; | 1988 |
Tachycardia of carotid chemoreceptors originates in apneic asphyxia in dogs.
Topics: Animals; Apnea; Blood Pressure; Bradycardia; Carotid Body; Dogs; Heart Rate; Oxygen; Sodium Cyanide; | 1987 |
Successful cardiovascular resuscitation after massive intravenous bupivacaine overdosage in anesthetized dogs.
Topics: Animals; Apnea; Atropine; Bradycardia; Bupivacaine; Dogs; Electrocardiography; Epinephrine; Female; | 1985 |
[Complications of regional anaesthesia and their treatment (author's transl)].
Topics: Adrenal Cortex Hormones; Anesthesia, Local; Apnea; Barbiturates; Bradycardia; Bupivacaine; Diagnosis | 1973 |
[Acute poisoning with nortriptyline].
Topics: Adult; Apnea; Bundle-Branch Block; Cardiac Complexes, Premature; Coma; Diuresis; Electrocardiography | 1969 |
Effects of inspiration, expiration, and apnea upon pacemaking and block in atrial fibrillation.
Topics: Apnea; Arrhythmia, Sinus; Atrial Fibrillation; Cardiac Complexes, Premature; Cheyne-Stokes Respirati | 1970 |
The effect of prophylactic and therapeutic administration of lithium on ventricular tachyarrhythmia.
Topics: Analysis of Variance; Animals; Apnea; Arrhythmias, Cardiac; Chloroform; Dogs; Female; Heart Rate; Li | 1974 |
Petit and grand mal convulsions during lidocaine hydrochloride treatment of ventricular tachycardia.
Topics: Apnea; Electrocardiography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Euphoria; Heart Ventricles; H | 1968 |
Respiratory and cardiovascular responses resulting from cooling the medulla oblongata in cats.
Topics: Anesthesia; Animals; Apnea; Blood Pressure; Body Temperature; Cats; Cold Temperature; Decerebrate St | 1972 |
[The value of different parameters in the assessment of extragenital symptoms in the menopause].
Topics: Adult; Affective Symptoms; Apnea; Climacteric; Depression; Epidemiologic Methods; Fatigue; Female; H | 1972 |
Intravenous diazepam for direct-current cardioversion.
Topics: Adolescent; Adult; Aged; Amnesia; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Atrial Fibri | 1971 |
Management of postoperative problems.
Topics: Apnea; Arrhythmias, Cardiac; Humans; Hypertension; Hypotension; Hypoventilation; Postoperative Compl | 1971 |
Myocardial infarction and fatal coronary insufficiency during electroconvulsive therapy.
Topics: Aged; Apnea; Arrhythmias, Cardiac; Blood Chemical Analysis; Blood Pressure; Bradycardia; Coronary Di | 1968 |
Circulatory and respiratory responses to postural changes in the hemorrhagic dog.
Topics: Animals; Apnea; Blood Circulation; Dogs; Heart; Heart Rate; Hemorrhage; Hypotension, Orthostatic; Ox | 1969 |
A clinical comparison of propanidid and thiopentone as induction agents to general anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthetics; Apnea; Blood Pressure; Child; Female; Halothane; Humans; Hyper | 1966 |