Page last updated: 2024-10-31

apnea and Sudden Unexpected Death in Epilepsy

apnea has been researched along with Sudden Unexpected Death in Epilepsy in 9 studies

Apnea: A transient absence of spontaneous respiration.

Sudden Unexpected Death in Epilepsy: Sudden death in a patient with EPILEPSY associated with SEIZURES and seizure-related symptoms (e.g., APNEA; HYPOXEMIA) without other identifiable accidental causes (e.g., DROWNING; WOUNDS AND INJURIES).

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to evaluate the incidence of ictal apnea (IA) and related hypoxemia during seizures."8.12Ictal apnea: A prospective monocentric study in patients with epilepsy. ( Ballerini, A; Cioclu, MC; Giovannini, G; Giunta, L; Meletti, S; Micalizzi, E; Talami, F; Turchi, G; Vaudano, AE, 2022)
"The primary cause of seizure-induced death for all mice was apnea, as (1) apnea began during a seizure and continued for tens of minutes until terminal asystole, and (2) death was prevented by mechanical ventilation."8.02Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy. ( Blizzard, EA; Goodkin, HP; Meisler, MH; Panchal, PS; Patel, MK; Richerson, GB; Saraf, P; Teran, FA; Wagley, PK; Wagnon, JL; Wengert, ER; Wenker, IC, 2021)
" However, the mechanisms underlying seizure-induced central apnea in pediatric epilepsy are unknown."7.96A human amygdala site that inhibits respiration and elicits apnea in pediatric epilepsy. ( Ciliberto, MA; Dlouhy, BJ; Harmata, GI; Howard, MA; Kovach, CK; Rhone, AE; Richerson, GB; Steinschneider, M; Sullivan, AW; Tranel, D; Wemmie, JA, 2020)
" We investigated volume changes and the microstructure of the amygdala in people with epilepsy at varied risk for SUDEP since that structure can play a key role in triggering apnea and mediating blood pressure."4.31Volumetric and microstructural abnormalities of the amygdala in focal epilepsy with varied levels of SUDEP risk. ( Allen, LA; Diehl, B; Duncan, JS; Harper, RM; Kassinopoulos, M; Kumar, R; Legouhy, A; Lemieux, L; Lhatoo, SD; Ogren, JA; Oliveira, JFA; Scott, C; Thom, M; Vos, SB; Winston, GP; Zhang, H, 2023)
" In addition, these mice developed baseline respiratory dysfunction prior to SUDEP, during which ictal apnea occurred long before terminal cardiac asystole."4.31Sudden Unexpected Death in Epilepsy and Respiratory Defects in a Mouse Model of DEPDC5-Related Epilepsy. ( Banerjee, R; Borna, NN; Cao, R; Hu, S; Kao, HY; Leventhal, DK; Li, P; Mir, MY; Parent, JM; Wang, S; Wang, Y; Yang, T; Yao, Y; Ziobro, J; Zylinski, M, 2023)
"Postictal apnea is thought to be a major cause of sudden unexpected death in epilepsy (SUDEP)."4.31Failure to breathe persists without air hunger or alarm following amygdala seizures. ( Chan, AC; Ciliberto, MA; Davenport, PW; Dlouhy, BJ; Gehlbach, BK; Harmata, GI; Howard, MA; Kawasaki, H; Kovach, CK; Kumar, S; Mowla, MR; Mueller, RN; Nagahama, Y; Oya, H; Pattinson, KT; Rhone, AE; Richerson, GB; Sainju, RK; Simonyan, K; Steinschneider, M; Wemmie, JA, 2023)
" The aim of this study was to evaluate the incidence of ictal apnea (IA) and related hypoxemia during seizures."4.12Ictal apnea: A prospective monocentric study in patients with epilepsy. ( Ballerini, A; Cioclu, MC; Giovannini, G; Giunta, L; Meletti, S; Micalizzi, E; Talami, F; Turchi, G; Vaudano, AE, 2022)
"The primary cause of seizure-induced death for all mice was apnea, as (1) apnea began during a seizure and continued for tens of minutes until terminal asystole, and (2) death was prevented by mechanical ventilation."4.02Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy. ( Blizzard, EA; Goodkin, HP; Meisler, MH; Panchal, PS; Patel, MK; Richerson, GB; Saraf, P; Teran, FA; Wagley, PK; Wagnon, JL; Wengert, ER; Wenker, IC, 2021)
"Immediately preceding sudden unexpected death in epilepsy (SUDEP), patients experienced a final generalized tonic-clonic seizure (GTCS), rapid ventilation, apnea, bradycardia, terminal apnea, and asystole."3.96Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin. ( Abel, PW; Aggarwal, A; Hallgren, J; Iyer, SH; Simeone, KA; Simeone, TA; Warren, TJ, 2020)
" However, the mechanisms underlying seizure-induced central apnea in pediatric epilepsy are unknown."3.96A human amygdala site that inhibits respiration and elicits apnea in pediatric epilepsy. ( Ciliberto, MA; Dlouhy, BJ; Harmata, GI; Howard, MA; Kovach, CK; Rhone, AE; Richerson, GB; Steinschneider, M; Sullivan, AW; Tranel, D; Wemmie, JA, 2020)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's9 (100.00)2.80

Authors

AuthorsStudies
Micalizzi, E1
Vaudano, AE1
Ballerini, A1
Talami, F1
Giovannini, G1
Turchi, G1
Cioclu, MC1
Giunta, L1
Meletti, S1
Wenker, IC2
Boscia, AR1
Lewis, C1
Tariq, A1
Miralles, R1
Hanflink, JC1
Saraf, P2
Patel, MK2
Legouhy, A1
Allen, LA1
Vos, SB1
Oliveira, JFA1
Kassinopoulos, M1
Winston, GP1
Duncan, JS1
Ogren, JA1
Scott, C1
Kumar, R1
Lhatoo, SD1
Thom, M1
Lemieux, L1
Harper, RM1
Zhang, H1
Diehl, B1
Kao, HY1
Yao, Y1
Yang, T1
Ziobro, J1
Zylinski, M1
Mir, MY1
Hu, S1
Cao, R1
Borna, NN1
Banerjee, R1
Parent, JM1
Wang, S1
Leventhal, DK1
Li, P1
Wang, Y1
Harmata, GI2
Rhone, AE2
Kovach, CK2
Kumar, S1
Mowla, MR1
Sainju, RK1
Nagahama, Y1
Oya, H1
Gehlbach, BK1
Ciliberto, MA2
Mueller, RN1
Kawasaki, H1
Pattinson, KT1
Simonyan, K1
Davenport, PW1
Howard, MA2
Steinschneider, M2
Chan, AC1
Richerson, GB3
Wemmie, JA2
Dlouhy, BJ2
Iyer, SH1
Aggarwal, A1
Warren, TJ1
Hallgren, J1
Abel, PW1
Simeone, TA1
Simeone, KA1
Sullivan, AW1
Tranel, D1
Katayama, PL1
Teran, FA1
Wengert, ER1
Wagley, PK1
Panchal, PS1
Blizzard, EA1
Wagnon, JL1
Goodkin, HP1
Meisler, MH1

Other Studies

9 other studies available for apnea and Sudden Unexpected Death in Epilepsy

ArticleYear
Ictal apnea: A prospective monocentric study in patients with epilepsy.
    European journal of neurology, 2022, Volume: 29, Issue:12

    Topics: Apnea; Electroencephalography; Epilepsy; Epilepsy, Generalized; Humans; Hypoxia; Prospective Studies

2022
Forebrain epileptiform activity is not required for seizure-induced apnea in a mouse model of
    Frontiers in neural circuits, 2022, Volume: 16

    Topics: Animals; Apnea; Clozapine; Designer Drugs; Disease Models, Animal; Epilepsy; Ligands; Mice; Mice, Tr

2022
Volumetric and microstructural abnormalities of the amygdala in focal epilepsy with varied levels of SUDEP risk.
    Epilepsy research, 2023, Volume: 192

    Topics: Amygdala; Apnea; Diffusion Tensor Imaging; Epilepsies, Partial; Epilepsy; Humans; Sudden Unexpected

2023
Sudden Unexpected Death in Epilepsy and Respiratory Defects in a Mouse Model of DEPDC5-Related Epilepsy.
    Annals of neurology, 2023, Volume: 94, Issue:5

    Topics: Animals; Apnea; Death, Sudden; Epilepsies, Partial; Epilepsy; GTPase-Activating Proteins; Mice; Seiz

2023
Failure to breathe persists without air hunger or alarm following amygdala seizures.
    JCI insight, 2023, Nov-22, Volume: 8, Issue:22

    Topics: Adult; Amygdala; Apnea; Carbon Dioxide; Child; Electroencephalography; Humans; Hunger; Seizures; Sud

2023
Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin.
    Epilepsia, 2020, Volume: 61, Issue:3

    Topics: Animals; Apnea; Bradycardia; Epilepsy; Heart Rate; Hypothalamic Area, Lateral; Hypoxia; Kv1.1 Potass

2020
A human amygdala site that inhibits respiration and elicits apnea in pediatric epilepsy.
    JCI insight, 2020, 03-26, Volume: 5, Issue:6

    Topics: Adolescent; Amygdala; Apnea; Child; Child, Preschool; Electrocorticography; Epilepsy; Female; Humans

2020
Cardiorespiratory Dysfunction Induced by Brainstem Spreading Depolarization: A Potential Mechanism for SUDEP.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020, 03-18, Volume: 40, Issue:12

    Topics: Animals; Apnea; Brain Stem; Medulla Oblongata; Mice; Seizures; Sudden Unexpected Death in Epilepsy

2020
Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy.
    Annals of neurology, 2021, Volume: 89, Issue:5

    Topics: Animals; Apnea; Convulsants; Diaphragm; Electroencephalography; Electromyography; Epilepsy; Female;

2021