apnea has been researched along with Kernicterus in 7 studies
Apnea: A transient absence of spontaneous respiration.
Kernicterus: A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Central apnea, defined as cessation of breathing for ≥20s, is frequent in premature infants born at <34 weeks׳ gestation but uncommon among healthy late preterm (34(0/7)-36(6/7) weeks׳ gestation) and term (≥37 weeks׳ gestation) infants, where it is usually a clinical manifestation of a neurological or metabolic problem." | 8.90 | Apnea in acute bilirubin encephalopathy. ( Amin, SB; Bhutani, VK; Watchko, JF, 2014) |
| "Apnea of prematurity (AoP) is, in part, a reflection of brainstem-mediated respiratory control system maturation." | 7.73 | Transient bilirubin encephalopathy and apnea of prematurity in 28 to 32 weeks gestational age infants. ( Amin, SB; Charafeddine, L; Guillet, R, 2005) |
| "Central apnea, defined as cessation of breathing for ≥20s, is frequent in premature infants born at <34 weeks׳ gestation but uncommon among healthy late preterm (34(0/7)-36(6/7) weeks׳ gestation) and term (≥37 weeks׳ gestation) infants, where it is usually a clinical manifestation of a neurological or metabolic problem." | 4.90 | Apnea in acute bilirubin encephalopathy. ( Amin, SB; Bhutani, VK; Watchko, JF, 2014) |
| "Apnea of prematurity (AoP) is, in part, a reflection of brainstem-mediated respiratory control system maturation." | 3.73 | Transient bilirubin encephalopathy and apnea of prematurity in 28 to 32 weeks gestational age infants. ( Amin, SB; Charafeddine, L; Guillet, R, 2005) |
| " Preterm newborns are particularly vulnerable secondary to central nervous system immaturity and concurrent adverse clinical conditions that may potentiate bilirubin toxicity." | 2.53 | Bilirubin-Induced Neurotoxicity in the Preterm Neonate. ( Watchko, JF, 2016) |
| "The incidence of kernicterus is Norway is much lower than in other industrialised countries." | 1.42 | [A 14-day-old boy with jaundice and apnoea]. ( Grønn, M; Hansen, TW; Smerud, OJ; Solevåg, AL, 2015) |
| "Hypothermia leads to hypoxemia, acidosis, hypoglycemia, kernicterus and other lethal complications." | 1.26 | Thermoregulation of the newborn. ( Calvert, LJ; Kanto, WP, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amin, SB | 2 |
| Bhutani, VK | 1 |
| Watchko, JF | 2 |
| Smerud, OJ | 1 |
| Solevåg, AL | 1 |
| Hansen, TW | 1 |
| Grønn, M | 1 |
| Selbst, SM | 1 |
| Charafeddine, L | 1 |
| Guillet, R | 1 |
| Kanto, WP | 1 |
| Calvert, LJ | 1 |
| Brüster, H | 1 |
| Wirtz, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Magnetic Resonance Spectroscopy and Auditory Brain- Stem Response Audiometry as Early Predictors of Bilirubin-Induced Neurologic Dysfunction in Full-term Jaundiced Neonates[NCT06018012] | 76 participants (Actual) | Observational | 2019-03-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for apnea and Kernicterus
| Article | Year |
|---|---|
Apnea in acute bilirubin encephalopathy.
Topics: Apnea; Bilirubin; Gestational Age; Humans; Hyperbilirubinemia, Neonatal; Infant, Newborn; Infant, Pr | 2014 |
Bilirubin-Induced Neurotoxicity in the Preterm Neonate.
Topics: Apnea; Apoptosis; Bilirubin; Brain; Calcium; Cell Cycle; Cell Cycle Checkpoints; Cell Membrane; Diff | 2016 |
5 other studies available for apnea and Kernicterus
| Article | Year |
|---|---|
[A 14-day-old boy with jaundice and apnoea].
Topics: Apnea; Bilirubin; Crigler-Najjar Syndrome; Humans; Infant, Newborn; Jaundice, Neonatal; Kernicterus; | 2015 |
Pediatric emergency medicine: legal briefs.
Topics: Abdomen, Acute; Accidents, Traffic; Adolescent; Aortic Aneurysm, Abdominal; Aortic Rupture; Apnea; B | 2009 |
Transient bilirubin encephalopathy and apnea of prematurity in 28 to 32 weeks gestational age infants.
Topics: Apnea; Bilirubin; Evoked Potentials, Auditory, Brain Stem; Gestational Age; Humans; Infant, Newborn; | 2005 |
Thermoregulation of the newborn.
Topics: Acidosis; Apnea; Body Temperature Regulation; Environment; Humans; Hypoglycemia; Hypothermia; Hypoxi | 1977 |
[Indications for exchange transfusions in premature infants].
Topics: Acidosis, Respiratory; Apnea; Birth Weight; Exchange Transfusion, Whole Blood; Female; Humans; Hyper | 1969 |