Page last updated: 2024-10-31

apnea and Decerebrate Posturing

apnea has been researched along with Decerebrate Posturing in 32 studies

Apnea: A transient absence of spontaneous respiration.

Research Excerpts

ExcerptRelevanceReference
"We tested the hypotheses that elevated body temperature would prolong reflex apnea following electrical stimulation of the superior laryngeal nerve (SLN) in decerebrate neonatal piglets and that thermal prolongation of reflex apnea after stimulation of the SLN depended on GABAergic mechanisms."7.74GABAergic processes mediate thermal prolongation of the laryngeal reflex apnea in decerebrate piglets. ( Bartlett, D; Böhm, I; Leiter, JC; Xia, L, 2007)
" Elevating body temperature by approximately 2 degrees C prolongs the duration of the LCR and the length of apnea associated with the reflex."7.74Elevated body temperature exaggerates laryngeal chemoreflex apnea in decerebrate piglets. ( Bartlett, D; Damon, T; Leiter, JC; Xia, L, 2008)
" All the stimulations produced apneas of variable duration, and expiratory reinforcement was associated with activation of pretracheal muscles."7.69Nonvagal reflex apnea in the newborn kitten and during the early postnatal period. ( Duron, B; Khater-Boidin, J; Toussaint, P; Wallois, F, 1994)
"8 nmol) into the nucleus paragigantocellularis and the nucleus reticularis lateralis of the ventrolateral medulla oblongata induced ventilatory depression and apnea."7.68Local application of somatostatin in the rat ventrolateral brain medulla induces apnea. ( Chen, ZB; Hedner, J; Hedner, T, 1990)
" In the encéphale isolé group awakening reduced TE and TI and brought them close to their prelesion values following both NPBM and KF lesion; on the other hand light sleep induced by pentobarbital led to expiratory apnea after KF lesion and reduced IPD amplitude to zero after NPBM lesion."7.66Apneusis and apnea after parabrachial or Kölliker-Fuse N. lesion; influence of wakefulness. ( Caille, D; Hugelin, A; Vibert, JF, 1981)
" We report a case of a 19-month-old girl who presented in coma and who was later found to have a fentanyl patch adhered to her back."3.77Toxic leukoencephalopathy due to transdermal fentanyl overdose. ( Bradin, SA; Foy, L; Seeyave, DM, 2011)
"We tested the hypotheses that elevated body temperature would prolong reflex apnea following electrical stimulation of the superior laryngeal nerve (SLN) in decerebrate neonatal piglets and that thermal prolongation of reflex apnea after stimulation of the SLN depended on GABAergic mechanisms."3.74GABAergic processes mediate thermal prolongation of the laryngeal reflex apnea in decerebrate piglets. ( Bartlett, D; Böhm, I; Leiter, JC; Xia, L, 2007)
"The laryngeal chemoreflex (LCR) is elicited by water in the larynx and leads to apnea and respiratory disruption in immature animals."3.74Unilateral microdialysis of gabazine in the dorsal medulla reverses thermal prolongation of the laryngeal chemoreflex in decerebrate piglets. ( Bartlett, D; Damon, T; Leiter, JC; Niblock, MM; Xia, L, 2007)
" Elevating body temperature by approximately 2 degrees C prolongs the duration of the LCR and the length of apnea associated with the reflex."3.74Elevated body temperature exaggerates laryngeal chemoreflex apnea in decerebrate piglets. ( Bartlett, D; Damon, T; Leiter, JC; Xia, L, 2008)
" Experiments were performed on nine unanesthetized, chemo- and barodenervated, decerebrate adult rats, in which asphyxia elicited hyperpnea, followed by apnea and gasping."3.73Selective loss of high-frequency oscillations in phrenic and hypoglossal activity in the decerebrate rat during gasping. ( Marchenko, V; Rogers, RF, 2006)
" They also increased reactivity to CO(2) by lowering the phrenic nerve apnea threshold and shifting the phrenic nerve-CO(2) response curve to lower et(CO(2)) levels."3.72Dopamine1 receptor agonists reverse opioid respiratory network depression, increase CO2 reactivity. ( Lalley, PM, 2004)
" After provocation of intracranial hypertension, we observed signs of brain death (absence of response to pain stimulus in one cranial par absence of brainstem reflexes, and apnea) in the experimental animals, and the velocity of flow in arteries at the base of the skull acquired the waveform known as sharp systolic peaks, which are characteristic of cerebral circulation failure."3.71[Diagnosis of brain death using trancranial Doppler ultrasonography in an experimental model of organ donation for transplantation]. ( Cerro Sánchez, J; Domínguez Roldán, JM; Hernández Fernández, A; Ojeda Rivero, R; Ordóñez Fernández, A, 2002)
" All the stimulations produced apneas of variable duration, and expiratory reinforcement was associated with activation of pretracheal muscles."3.69Nonvagal reflex apnea in the newborn kitten and during the early postnatal period. ( Duron, B; Khater-Boidin, J; Toussaint, P; Wallois, F, 1994)
"8 nmol) into the nucleus paragigantocellularis and the nucleus reticularis lateralis of the ventrolateral medulla oblongata induced ventilatory depression and apnea."3.68Local application of somatostatin in the rat ventrolateral brain medulla induces apnea. ( Chen, ZB; Hedner, J; Hedner, T, 1990)
" In the encéphale isolé group awakening reduced TE and TI and brought them close to their prelesion values following both NPBM and KF lesion; on the other hand light sleep induced by pentobarbital led to expiratory apnea after KF lesion and reduced IPD amplitude to zero after NPBM lesion."3.66Apneusis and apnea after parabrachial or Kölliker-Fuse N. lesion; influence of wakefulness. ( Caille, D; Hugelin, A; Vibert, JF, 1981)
" However, isocapnic hypoxia induced time-dependent changes in the pattern of phrenic discharge including diminutions in depth, an onset of gasping-type activity, or expiratory apnea."3.66Differential alteration by hypercapnia and hypoxia of the apneustic respiratory pattern in decerebrate cats. ( St John, WM, 1979)
"During acute progressive asphyxia an abrupt transition occurs from regular respiratory efforts to primary apnea and gasping."3.65Respiratory patterns during progressive asphyxia in newborn rabbits. ( Lawson, EE; Thach, BT, 1977)
" In spontaneously breathing animals, active hyperventilation (HV) was followed by hyperpnea for up to 30 s and never by apnea."3.65Central neural stimulation of respiration in unanesthetized decerebrate cats. ( Eldridge, FL, 1976)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199016 (50.00)18.7374
1990's6 (18.75)18.2507
2000's8 (25.00)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Foy, L1
Seeyave, DM1
Bradin, SA1
Fiamma, MN1
O'Connor, ET1
Roy, A1
Zuna, I1
Wilson, RJ1
Ojeda Rivero, R1
Cerro Sánchez, J1
Ordóñez Fernández, A1
Domínguez Roldán, JM1
Hernández Fernández, A1
KORNEVA, EA1
IAKOVLEVA, MI1
HOCKADAY, JM1
POTTS, F1
EPSTEIN, E1
BONAZZI, A1
SCHWAB, RS1
Lalley, PM1
St-John, WM1
Paton, JF1
Marchenko, V2
Rogers, RF2
Böhm, I1
Xia, L3
Leiter, JC3
Bartlett, D3
Damon, T2
Niblock, MM1
Cozine, RA1
Ngai, SH1
Walker, JE2
Hoff, HE2
Huggins, RA2
Deavers, S2
Caille, D1
Vibert, JF1
Hugelin, A1
Khater-Boidin, J2
Wallois, F2
Toussaint, P1
Duron, B2
Dusaussoy, F1
St John, WM2
Eldridge, FL2
Cohen, MI1
Lawson, EE1
Thach, BT1
Pierrefiche, O1
Foutz, AS1
Champagnat, J1
Denavit-Saubié, M1
Whittaker, CK1
Chen, ZB1
Hedner, T1
Hedner, J1
Davis, PJ1
Macefield, G1
Nail, BS1
Flórez, J1
Tabatabai, M1
Schläfke, ME1
See, WR1
Massion, WH1
Loeschcke, HH1
Rex, MA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Trial of Device for Seizure Detection Using SEDline During Therapeutic Hypothermia in Cardiac Arrest Victims[NCT01946802]39 participants (Actual)Observational2014-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Area Under Receiver Operating Characteristics Curve (AUC) of SEDline for Seizure Detection

The Area under receiver operating characteristics curve (AUC) of SEDline represents the accuracy of the SEDline to detect seizures compared with the conventional EEG. (NCT01946802)
Timeframe: Within 72 hours after cardiac arrest

Interventionprobability (Number)
Frontal 4 Channel EEG1.00

Negative Predictive Value

Negative predictive value measured the percentage of seizure-negative identified by the conventional EEG in cases those were identified as seizure-negative by the SEDline. (NCT01946802)
Timeframe: Within 72 hours after cardiac arrest

Interventionpercentage of seizure (-) (Number)
Frontal 4 Channel EEG100

Percentage of Seizure-positive and Seizure-negative That Were Correctly Classified by the SEDline in All Evaluated Cases

Conventional EEG (gold standard for seizure detection) and SEDline monitoring will be conducted simultaneously for 30 minutes at During therapeutic hypothermia and rewarming (12 ~ 72 hours after cardiac arrest). Then, data retrieved from the conventional EEG and SEDline will be interpreted and analyzed for the presence of seizure. (NCT01946802)
Timeframe: Within 72 hours after cardiac arrest

Interventionpercentage of seizures (Number)
Frontal 4 Channel EEG100

Positive Predictive Value

Positive predictive value measured the percentage of seizures identified by the conventional EEG in cases those were identified as seizures by the SEDline. (NCT01946802)
Timeframe: Within 72 hours after cardiac arrest

Interventionpercentage of seizure (+) (Number)
Frontal 4 Channel EEG100

Sensitivity of SEDline for Seizure Detection

Sensitivity measured the percentage of seizures identified by the SEDline in cases those were identified as seizures by the conventional EEG. (NCT01946802)
Timeframe: Within 72 hours after cardiac arrest

Interventionpercentage of seizure (+) (Number)
Frontal 4 Channel EEG100

Specificity

Specificity measured the percentage of seizure-negative identified by the SEDline in cases those were identified as seizure-negative by the conventional EEG. (NCT01946802)
Timeframe: Within 72 hours after cardiac arrest

Interventionpercentage of seizure (-) (Number)
Frontal 4 Channel EEG100

Reviews

1 review available for apnea and Decerebrate Posturing

ArticleYear
Role of pontile mechanisms in the neurogenesis of eupnea.
    Respiratory physiology & neurobiology, 2004, Nov-15, Volume: 143, Issue:2-3

    Topics: Animals; Apnea; Decerebrate State; Medulla Oblongata; Nerve Net; Neurons; Periodicity; Phrenic Nerve

2004

Other Studies

31 other studies available for apnea and Decerebrate Posturing

ArticleYear
Toxic leukoencephalopathy due to transdermal fentanyl overdose.
    Pediatric emergency care, 2011, Volume: 27, Issue:9

    Topics: Accidents, Home; Administration, Cutaneous; Apnea; Child, Preschool; Coma; Decerebrate State; Delaye

2011
The essential role of peripheral respiratory chemoreceptor inputs in maintaining breathing revealed when CO2 stimulation of central chemoreceptors is diminished.
    The Journal of physiology, 2013, Mar-15, Volume: 591, Issue:6

    Topics: Animals; Apnea; Brain Stem; Carbon Dioxide; Carotid Body; Decerebrate State; Electric Stimulation; M

2013
[Diagnosis of brain death using trancranial Doppler ultrasonography in an experimental model of organ donation for transplantation].
    Revista espanola de anestesiologia y reanimacion, 2002, Volume: 49, Issue:5

    Topics: Animals; Apnea; Blinking; Blood Flow Velocity; Brain Death; Brain Stem; Carbon Dioxide; Catheterizat

2002
[SOME DATA ON THE ROLE OF THE HIGHER SEGMENTS OF THE BRAIN IN THE REACTION OF RESPIRATION TO AMINAZIN ADMINISTRATION].
    Biulleten' eksperimental'noi biologii i meditsiny, 1963, Volume: 56

    Topics: Animals; Apnea; Brain; Cats; Central Nervous System; Cerebral Cortex; Chlorpromazine; Decerebrate St

1963
ELECTROENCEPHALOGRAPHIC CHANGES IN ACUTE CEREBRAL ANOXIA FROM CARDIAC OR RESPIRATORY ARREST.
    Electroencephalography and clinical neurophysiology, 1965, Volume: 18

    Topics: Apnea; Decerebrate State; Electroencephalography; Electromyography; Heart Arrest; Humans; Hypoxia, B

1965
Dopamine1 receptor agonists reverse opioid respiratory network depression, increase CO2 reactivity.
    Respiratory physiology & neurobiology, 2004, Feb-25, Volume: 139, Issue:3

    Topics: Action Potentials; Analgesics, Opioid; Analysis of Variance; Animals; Apnea; Carbon Dioxide; Cats; D

2004
Time-frequency coherence analysis of phrenic and hypoglossal activity in the decerebrate rat during eupnea, hyperpnea, and gasping.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:5

    Topics: Animals; Apnea; Asphyxia; Decerebrate State; Electrophysiology; Hypoglossal Nerve; Male; Motor Neuro

2006
Selective loss of high-frequency oscillations in phrenic and hypoglossal activity in the decerebrate rat during gasping.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:5

    Topics: Animals; Apnea; Asphyxia; Decerebrate State; Electrophysiology; Fourier Analysis; Hypoglossal Nerve;

2006
GABAergic processes mediate thermal prolongation of the laryngeal reflex apnea in decerebrate piglets.
    Respiratory physiology & neurobiology, 2007, May-14, Volume: 156, Issue:2

    Topics: Analysis of Variance; Animals; Apnea; Body Temperature; Chemoreceptor Cells; Decerebrate State; Elec

2007
Unilateral microdialysis of gabazine in the dorsal medulla reverses thermal prolongation of the laryngeal chemoreflex in decerebrate piglets.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 103, Issue:5

    Topics: Animals; Animals, Newborn; Apnea; Body Temperature; Chemoreceptor Cells; Decerebrate State; GABA Ant

2007
Elevated body temperature exaggerates laryngeal chemoreflex apnea in decerebrate piglets.
    Advances in experimental medicine and biology, 2008, Volume: 605

    Topics: Animals; Apnea; Chemoreceptor Cells; Decerebrate State; Disease Models, Animal; Fever; Humans; Infan

2008
Medullary surface chemoreceptors and regulation of respiration in the cat.
    Journal of applied physiology, 1967, Volume: 22, Issue:1

    Topics: Animals; Apnea; Blood Pressure; Carbon Dioxide; Cats; Chloralose; Decerebrate State; Denervation; Me

1967
Influence of morphine on central control of respiration and circulation in the dog.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 170, Issue:1

    Topics: Animals; Apnea; Blood Pressure; Central Nervous System; Cerebral Decortication; Decerebrate State; D

1967
Influence of nalorphine on central control of respiration and circulation in the dog.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 170, Issue:1

    Topics: Animals; Apnea; Blood Circulation; Bradycardia; Central Nervous System; Cerebral Decortication; Dece

1967
Apneusis and apnea after parabrachial or Kölliker-Fuse N. lesion; influence of wakefulness.
    Respiration physiology, 1981, Volume: 45, Issue:1

    Topics: Animals; Apnea; Cats; Decerebrate State; Phrenic Nerve; Respiration; Sleep; Time Factors; Vagus Nerv

1981
Nonvagal reflex apnea in the newborn kitten and during the early postnatal period.
    Biology of the neonate, 1994, Volume: 65, Issue:1

    Topics: Anesthesia; Animals; Animals, Newborn; Apnea; Brain Stem; Cats; Decerebrate State; Electric Stimulat

1994
Oral stimulations induce apnoea in newborn kittens.
    Neuroreport, 1993, Volume: 4, Issue:7

    Topics: Aging; Anesthesia; Animals; Animals, Newborn; Apnea; Cats; Decerebrate State; Deglutition; Electric

1993
Rostral medullary respiratory neuronal activities of decerebrate cats in eupnea, apneusis and gasping.
    Respiration physiology, 1999, Jun-01, Volume: 116, Issue:1

    Topics: Animals; Apnea; Brain; Carbon Dioxide; Cats; Decerebrate State; Electrophysiology; Female; Hypoxia;

1999
Maintenance of respiration by central neural feedback mechanisms.
    Federation proceedings, 1977, Volume: 36, Issue:10

    Topics: Anesthesia; Animals; Apnea; Carbon Dioxide; Carotid Body; Cats; Decerebrate State; Feedback; Humans;

1977
Neurogenesis of respiratory rhythm in the mammal.
    Physiological reviews, 1979, Volume: 59, Issue:4

    Topics: Action Potentials; Animals; Apnea; Brain Mapping; Brain Stem; Cats; Decerebrate State; Electric Stim

1979
Differential alteration by hypercapnia and hypoxia of the apneustic respiratory pattern in decerebrate cats.
    The Journal of physiology, 1979, Volume: 287

    Topics: Animals; Apnea; Brain Stem; Carbon Dioxide; Carotid Sinus; Cats; Chemoreceptor Cells; Decerebrate St

1979
Respiratory patterns during progressive asphyxia in newborn rabbits.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1977, Volume: 43, Issue:3

    Topics: Airway Obstruction; Animals; Animals, Newborn; Apnea; Asphyxia; Decerebrate State; Functional Residu

1977
Central neural stimulation of respiration in unanesthetized decerebrate cats.
    Journal of applied physiology, 1976, Volume: 40, Issue:1

    Topics: Animals; Apnea; Brain; Carbon Dioxide; Carotid Sinus; Cats; Decerebrate State; Gallamine Triethiodid

1976
The bulbar network of respiratory neurons during apneusis induced by a blockade of NMDA receptors.
    Experimental brain research, 1992, Volume: 89, Issue:3

    Topics: Animals; Apnea; Cats; Decerebrate State; Dizocilpine Maleate; Evoked Potentials; Inhalation; Iontoph

1992
Spinal man after declaration of brain death.
    Neurosurgery, 1992, Volume: 30, Issue:3

    Topics: Apnea; Brain Death; Decerebrate State; Evoked Potentials; Humans; Male

1992
Local application of somatostatin in the rat ventrolateral brain medulla induces apnea.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 69, Issue:6

    Topics: Animals; Apnea; Carbon Dioxide; Decerebrate State; Male; Medulla Oblongata; Microinjections; Partial

1990
Respiratory muscle activity during asphyxic apnoea and opisthotonus in the rabbit.
    Respiration physiology, 1986, Volume: 65, Issue:3

    Topics: Animals; Apnea; Asphyxia; Carotid Sinus; Decerebrate State; Denervation; Electromyography; Muscle Sp

1986
The site of the respiratory stimulant action of imidazole in cats.
    Pharmacology, 1974, Volume: 11, Issue:5

    Topics: Animals; Apnea; Blood Pressure; Cats; Cerebral Ventricles; Decerebrate State; Hypothalamus; Imidazol

1974
Respiratory and cardiovascular responses resulting from cooling the medulla oblongata in cats.
    The American journal of physiology, 1972, Volume: 223, Issue:1

    Topics: Anesthesia; Animals; Apnea; Blood Pressure; Body Temperature; Cats; Cold Temperature; Decerebrate St

1972
[Role of "specific" and non-specific afferent fibers in the drive of respiration, studied by stimulation and blockade of afferent fibers in decerebrate cats].
    Pflugers Archiv : European journal of physiology, 1969, Volume: 312, Issue:4

    Topics: Animals; Apnea; Carbon Dioxide; Cats; Cold Temperature; Decerebrate State; Electric Stimulation; Glo

1969
The production of laryngospasm in the cat by volatile anaesthetic agents.
    British journal of anaesthesia, 1970, Volume: 42, Issue:11

    Topics: Anesthesia, Intravenous; Animals; Apnea; Cats; Chloralose; Decerebrate State; Electromyography; Ethy

1970