apnea has been researched along with Brain Injuries in 40 studies
Apnea: A transient absence of spontaneous respiration.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Brain death testing with conventional apnea testing was attempted but aborted due to hypoxia." | 7.83 | The Modified Apnea Test During Brain Death Determination: An Alternative in Patients With Hypoxia. ( Ahlawat, A; Carandang, R; Heard, SO; Muehlschlegel, S, 2016) |
| "A 42-year-old man with a subarachnoid hemorrhage complicated by anoxic brain injury, respiratory failure requiring mechanical ventilation, and severe acute respiratory distress syndrome (ARDS) presented a clinical conundrum for safe apnea testing in brain death determination due to profound hypoxemia." | 7.80 | Apnea testing for brain death in severe acute respiratory distress syndrome: a possible solution. ( Hocker, S; Whalen, F; Wijdicks, EF, 2014) |
| "We performed a detailed chart review of consecutive brain dead patients who underwent an apnea test from 2008 to 2012." | 7.80 | Completing the apnea test: decline in complications. ( Couillard, P; Datar, S; Fugate, J; Rabinstein, A; Wijdicks, EF, 2014) |
| " We wanted to investigate whether a voluntary, prolonged apnea in trained breath-hold divers resulted in an increase of S100B in serum." | 7.75 | Increased serum levels of the brain damage marker S100B after apnea in trained breath-hold divers: a study including respiratory and cardiovascular observations. ( Andersson, JP; Jönsson, H; Linér, MH, 2009) |
| "By using our model for predicting MAP and PCO2 prior to apnea testing, hemodynamic embarrassment can be anticipated and prevented, thus allowing a safer procedure in the detection of brain death." | 7.69 | Apnea testing in suspected brain dead children--physiological and mathematical modelling. ( Barzilay, Z; Paret, G, 1995) |
| " From the review, we have identified four major groups of external circumstances for rather sudden cardiopulmonary arrest from brain damage in children, after excluding congenital and other unrelated diseases; 1) impact brain apnea, 2) anoxic insults, 3) drug or other substance induced central nervous system depression, and 4) traumatic brain damage." | 5.05 | A review on four different paths to respiratory arrest from brain injury in children; implications for child abuse. ( Kwon, DI; Paek, D, 2020) |
| "Patients with multiple trauma presenting with apnea or a gasping breathing pattern (respiratory rate <6/min) require prehospital endotracheal intubation (ETI) and ventilation." | 4.87 | [Emergency anesthesia, airway management and ventilation in major trauma. Background and key messages of the interdisciplinary S3 guidelines for major trauma patients]. ( Bernhard, M; Böttiger, BW; Fischbacher, M; Fischer, M; Kanz, KG; Matthes, G; Waydhas, C, 2011) |
| " The various contributions of shaking alone, shaking with impact, and apnea are discussed." | 4.82 | Shaking-impact syndrome of infancy. ( Deputy, S, 2003) |
| " Step 2 comprises the clinical investigation of reactivity to external stimuli and the upper, middle and lower brain stem reflexes including apnea testing." | 4.02 | [Irreversible loss of brain function : Requirements and Clinical diagnosis]. ( Els, T; Hansen, HC; Soeffker, G; Wertheimer, D, 2021) |
| " Apnea testing was performed for 1 patient due to the decision to withdraw treatment (n = 2), concern for inability to tolerate testing (n = 2) and observation of spontaneous respirations (n = 1)." | 3.96 | Special considerations in the assessment of catastrophic brain injury and determination of brain death in patients with SARS-CoV-2. ( Agarwal, S; Bondi, S; Carroll, E; Czeisler, B; Frontera, J; Gurin, L; Kvernland, A; Kwon, P; Lewis, A; Snyder, T; Valdes, E, 2020) |
| " Brain death testing with conventional apnea testing was attempted but aborted due to hypoxia." | 3.83 | The Modified Apnea Test During Brain Death Determination: An Alternative in Patients With Hypoxia. ( Ahlawat, A; Carandang, R; Heard, SO; Muehlschlegel, S, 2016) |
| "Cardiopulmonary resuscitation (CPR) was implemented on apnea-induced SCA rabbit models." | 3.81 | The effect of therapeutic hypothermia after cardiopulmonary resuscitation on ICAM-1 and NSE levels in sudden cardiac arrest rabbits. ( Chen, Y; Jin, Y; Zhao, H, 2015) |
| " TBI induced apnea and a delay in righting reflex." | 3.80 | Acute alcohol intoxication prolongs neuroinflammation without exacerbating neurobehavioral dysfunction following mild traumatic brain injury. ( Molina, PE; Teng, SX, 2014) |
| "A 42-year-old man with a subarachnoid hemorrhage complicated by anoxic brain injury, respiratory failure requiring mechanical ventilation, and severe acute respiratory distress syndrome (ARDS) presented a clinical conundrum for safe apnea testing in brain death determination due to profound hypoxemia." | 3.80 | Apnea testing for brain death in severe acute respiratory distress syndrome: a possible solution. ( Hocker, S; Whalen, F; Wijdicks, EF, 2014) |
| "We performed a detailed chart review of consecutive brain dead patients who underwent an apnea test from 2008 to 2012." | 3.80 | Completing the apnea test: decline in complications. ( Couillard, P; Datar, S; Fugate, J; Rabinstein, A; Wijdicks, EF, 2014) |
| " Our results indicate that a dorsal directed closed-head OB injury results in a neurally mediated apnea followed by respiratory timing changes." | 3.80 | Respiratory responses following blast-induced traumatic brain injury in rats. ( Adams, S; Condrey, JA; Davenport, PW; Svetlov, SI; Tsai, HW, 2014) |
| " Patients with catastrophic brain injury and absent cranial nerve function should undergo immediate formal apnea testing." | 3.77 | Ventilator autocycling and delayed recognition of brain death. ( Mailloux, P; McGee, WT, 2011) |
| "5-cm group show that 87% rats developed apnea, limb seizure, poor appetite, and limpness." | 3.76 | Development of a rat model for studying blast-induced traumatic brain injury. ( Cheng, J; Gu, J; Kang, J; Kuang, Y; Li, B; Ma, Y; Yang, T, 2010) |
| " General findings include a significantly longer duration of unconsciousness in LE rats, but similar durations of apnea." | 3.75 | Strain differences in response to traumatic brain injury in Long-Evans compared to Sprague-Dawley rats. ( Hoane, MR; Quigley, A; Smith, DC; Tan, AA, 2009) |
| " We wanted to investigate whether a voluntary, prolonged apnea in trained breath-hold divers resulted in an increase of S100B in serum." | 3.75 | Increased serum levels of the brain damage marker S100B after apnea in trained breath-hold divers: a study including respiratory and cardiovascular observations. ( Andersson, JP; Jönsson, H; Linér, MH, 2009) |
| " We first validated the severity of the initial injury using physiologic criteria, including apnea and blood pressure, during the immediate postinjury period." | 3.74 | Injury severity determines Purkinje cell loss and microglial activation in the cerebellum after cortical contusion injury. ( Igarashi, T; Noble-Haeusslein, LJ; Potts, MB, 2007) |
| "It has been observed that traumatic brain injury (TBI) increases the susceptibility of the brain to subsequent hypoxia, and prolonged apnea occurs in ethanol (EtOH)-treated animals following brain injury." | 3.69 | Effects of ethanol on respiratory function in traumatic brain injury. ( Feustel, PJ; Zink, BJ, 1995) |
| "By using our model for predicting MAP and PCO2 prior to apnea testing, hemodynamic embarrassment can be anticipated and prevented, thus allowing a safer procedure in the detection of brain death." | 3.69 | Apnea testing in suspected brain dead children--physiological and mathematical modelling. ( Barzilay, Z; Paret, G, 1995) |
| "The diagnosis of death by neurologic criteria implies that there is clinical evidence of the complete and irreversible cessation of brainstem and cerebral functions." | 2.61 | Death by neurologic criteria: pathophysiology, definition, diagnostic criteria and tests. ( Citerio, G; Iaquaniello, C; Robba, C, 2019) |
| "Seizures and long bone fractures were not discriminatory, and skull fracture and head/neck bruising were more associated with niBI, although not significantly so." | 2.45 | Which clinical features distinguish inflicted from non-inflicted brain injury? A systematic review. ( Farewell, D; Kemp, AM; Maguire, S; Mann, M; Pickerd, N; Tempest, V, 2009) |
| "No patient was found to have retinal hemorrhages nor was any found to have experienced child abuse." | 1.36 | Retinal hemorrhages and apparent life-threatening events. ( Curcoy, AI; Morales, M; Pou, J; Serra, A; Trenchs, V, 2010) |
| "Confirmation of brain death requires an urgent diagnosis to allow rapid vital organ removal for transplantation." | 1.31 | Brain death assessment using instant spectral analysis of heart rate variability. ( Baillard, C; Jasson, S; Mangin, L; Mansier, P; Riou, B; Swynghedauw, B; Vivien, B, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (25.00) | 18.7374 |
| 1990's | 3 (7.50) | 18.2507 |
| 2000's | 11 (27.50) | 29.6817 |
| 2010's | 13 (32.50) | 24.3611 |
| 2020's | 3 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| Paek, D | 1 |
| Kwon, DI | 1 |
| Valdes, E | 1 |
| Agarwal, S | 1 |
| Carroll, E | 1 |
| Kvernland, A | 1 |
| Bondi, S | 1 |
| Snyder, T | 1 |
| Kwon, P | 1 |
| Frontera, J | 1 |
| Gurin, L | 1 |
| Czeisler, B | 1 |
| Lewis, A | 1 |
| Hansen, HC | 1 |
| Wertheimer, D | 1 |
| Soeffker, G | 1 |
| Els, T | 1 |
| Fathi, A | 1 |
| Lake, JL | 1 |
| Robba, C | 1 |
| Iaquaniello, C | 1 |
| Citerio, G | 1 |
| Teng, SX | 1 |
| Molina, PE | 1 |
| Hocker, S | 1 |
| Whalen, F | 1 |
| Wijdicks, EF | 3 |
| Datar, S | 1 |
| Fugate, J | 1 |
| Rabinstein, A | 1 |
| Couillard, P | 1 |
| Zhao, H | 1 |
| Chen, Y | 1 |
| Jin, Y | 1 |
| Adams, S | 1 |
| Condrey, JA | 1 |
| Tsai, HW | 1 |
| Svetlov, SI | 1 |
| Davenport, PW | 1 |
| Ahlawat, A | 1 |
| Carandang, R | 1 |
| Heard, SO | 1 |
| Muehlschlegel, S | 1 |
| Tan, AA | 1 |
| Quigley, A | 1 |
| Smith, DC | 1 |
| Hoane, MR | 1 |
| Selbst, SM | 2 |
| Maguire, S | 1 |
| Pickerd, N | 1 |
| Farewell, D | 1 |
| Mann, M | 1 |
| Tempest, V | 1 |
| Kemp, AM | 1 |
| Andersson, JP | 1 |
| Linér, MH | 1 |
| Jönsson, H | 1 |
| Curcoy, AI | 1 |
| Trenchs, V | 1 |
| Morales, M | 1 |
| Serra, A | 1 |
| Pou, J | 1 |
| Cheng, J | 1 |
| Gu, J | 1 |
| Ma, Y | 1 |
| Yang, T | 1 |
| Kuang, Y | 1 |
| Li, B | 1 |
| Kang, J | 1 |
| McGee, WT | 1 |
| Mailloux, P | 1 |
| Bernhard, M | 1 |
| Matthes, G | 1 |
| Kanz, KG | 1 |
| Waydhas, C | 1 |
| Fischbacher, M | 1 |
| Fischer, M | 1 |
| Böttiger, BW | 1 |
| TONNIS, W | 1 |
| FROWEIN, RA | 2 |
| TOENNIS, W | 1 |
| CLEAVE, HL | 1 |
| CHRISTIE, TH | 1 |
| Deputy, S | 1 |
| ELSASSER, G | 1 |
| THEWALT, W | 1 |
| Manno, EM | 1 |
| Holets, SR | 1 |
| Igarashi, T | 1 |
| Potts, MB | 1 |
| Noble-Haeusslein, LJ | 1 |
| Swischuk, LE | 1 |
| Duhaime, AC | 1 |
| Durham, S | 1 |
| Zink, BJ | 1 |
| Feustel, PJ | 1 |
| Paret, G | 1 |
| Barzilay, Z | 1 |
| Baillard, C | 1 |
| Vivien, B | 1 |
| Mansier, P | 1 |
| Mangin, L | 1 |
| Jasson, S | 1 |
| Riou, B | 1 |
| Swynghedauw, B | 1 |
| Ip, EY | 1 |
| Giza, CC | 1 |
| Griesbach, GS | 1 |
| Hovda, DA | 1 |
| Teasdale, G | 1 |
| Parker, L | 1 |
| Murray, G | 1 |
| Knill-Jones, R | 1 |
| Jennett, B | 1 |
| Serrats, AF | 1 |
| Parker, SA | 1 |
| Levine, JE | 1 |
| Becker, D | 1 |
| Chun, T | 1 |
| Korein, J | 1 |
| Braunstein, P | 1 |
| George, A | 1 |
| Wichter, M | 1 |
| Kricheff, I | 1 |
| Lieberman, A | 1 |
| Pearson, J | 1 |
| Mühlnickel, B | 1 |
| Brandt, W | 1 |
| North, JB | 1 |
| Jennett, S | 1 |
| Grubb, RL | 1 |
| Naumann, RA | 1 |
| Ommaya, AK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does Venous pCO2 Increase by 20 mmHg or More During Apnea Challenge Test?[NCT02503813] | 7 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Validation of Apnea Test Conducted Using High-flow Oxygen Therapy in Patients With Clinical Brain Death[NCT05950178] | 25 participants (Anticipated) | Interventional | 2023-07-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for apnea and Brain Injuries
| Article | Year |
|---|---|
A review on four different paths to respiratory arrest from brain injury in children; implications for child abuse.
Topics: Animals; Apnea; Brain Injuries; Brain Injuries, Traumatic; Brain Stem; Central Nervous System Depres | 2020 |
Death by neurologic criteria: pathophysiology, definition, diagnostic criteria and tests.
Topics: Apnea; Brain; Brain Death; Brain Injuries; Brain Stem; Coma; Death; Diabetes Insipidus; Diagnosis, D | 2019 |
Which clinical features distinguish inflicted from non-inflicted brain injury? A systematic review.
Topics: Adolescent; Apnea; Bones of Lower Extremity; Bones of Upper Extremity; Brain Injuries; Child; Child | 2009 |
[Emergency anesthesia, airway management and ventilation in major trauma. Background and key messages of the interdisciplinary S3 guidelines for major trauma patients].
Topics: Airway Management; Anesthesia; Anesthesiology; Apnea; Blood Gas Analysis; Brain Injuries; Capnograph | 2011 |
[CENTRAL RESPIRATORY DISORDERS IN CEREBROCRANIAL INJURIES AND BRAIN TUMORS. EFFECT OF TYPE AND LOCALIZATION OF THE PROCESS OF INTRACRANIAL PRESSURE INCREASE AND BRAIN SURGERY ON THE CENTRAL REGULATION OF RESPIRATION].
Topics: Apnea; Blood Gas Analysis; Brain; Brain Injuries; Brain Neoplasms; Central Nervous System; Humans; I | 1963 |
Shaking-impact syndrome of infancy.
Topics: Apnea; Autopsy; Battered Child Syndrome; Brain Injuries; Child; Diagnosis, Differential; Humans; Inf | 2003 |
Traumatic brain injury in infants: the phenomenon of subdural hemorrhage with hemispheric hypodensity ("Big Black Brain").
Topics: Animals; Apnea; Brain Edema; Brain Injuries; Disease Models, Animal; Hematoma, Subdural, Intracrania | 2007 |
33 other studies available for apnea and Brain Injuries
| Article | Year |
|---|---|
Special considerations in the assessment of catastrophic brain injury and determination of brain death in patients with SARS-CoV-2.
Topics: Aged; Apnea; Betacoronavirus; Brain Death; Brain Injuries; Cerebral Hemorrhage; Contraindications, P | 2020 |
[Irreversible loss of brain function : Requirements and Clinical diagnosis].
Topics: Apnea; Brain; Brain Death; Brain Injuries; Extracorporeal Membrane Oxygenation; Humans | 2021 |
Use of Venous Pco
Topics: Adolescent; Apnea; Brain Death; Brain Injuries; Carbon Dioxide; Child; Child, Preschool; Cohort Stud | 2019 |
Acute alcohol intoxication prolongs neuroinflammation without exacerbating neurobehavioral dysfunction following mild traumatic brain injury.
Topics: Alcoholic Intoxication; Animals; Apnea; Behavior, Animal; Brain Injuries; Central Nervous System Dep | 2014 |
Apnea testing for brain death in severe acute respiratory distress syndrome: a possible solution.
Topics: Adult; Apnea; Brain Death; Brain Injuries; Humans; Hypoxia; Male; Respiratory Distress Syndrome; Sev | 2014 |
Completing the apnea test: decline in complications.
Topics: Adult; Apnea; Blood Gas Analysis; Brain Death; Brain Injuries; Cohort Studies; Diagnostic Techniques | 2014 |
The effect of therapeutic hypothermia after cardiopulmonary resuscitation on ICAM-1 and NSE levels in sudden cardiac arrest rabbits.
Topics: Animals; Apnea; Brain Injuries; Cardiopulmonary Resuscitation; Death, Sudden, Cardiac; Disease Model | 2015 |
Respiratory responses following blast-induced traumatic brain injury in rats.
Topics: Animals; Apnea; Blast Injuries; Brain Injuries; Diaphragm; Disease Models, Animal; Electrodes, Impla | 2014 |
The Modified Apnea Test During Brain Death Determination: An Alternative in Patients With Hypoxia.
Topics: Adult; Apnea; Blood Gas Analysis; Brain Death; Brain Injuries; Carbon Dioxide; Continuous Positive A | 2016 |
Strain differences in response to traumatic brain injury in Long-Evans compared to Sprague-Dawley rats.
Topics: Animals; Animals, Outbred Strains; Apnea; Behavior, Animal; Brain; Brain Injuries; Cognition Disorde | 2009 |
Pediatric emergency medicine: legal briefs.
Topics: Abdomen, Acute; Accidents, Traffic; Adolescent; Aortic Aneurysm, Abdominal; Aortic Rupture; Apnea; B | 2009 |
Increased serum levels of the brain damage marker S100B after apnea in trained breath-hold divers: a study including respiratory and cardiovascular observations.
Topics: Adult; Apnea; Blood Gas Analysis; Blood Pressure; Brain Injuries; Carbon Dioxide; Cardiovascular Phy | 2009 |
Retinal hemorrhages and apparent life-threatening events.
Topics: Acute Disease; Apnea; Brain Injuries; Child Abuse; Comorbidity; Diagnostic Tests, Routine; Emergenci | 2010 |
Pediatric emergency medicine: legal briefs.
Topics: Accidental Falls; Adolescent; Adult; Antiemetics; Apnea; Bacteremia; Baseball; Brain Injuries; Cardi | 2010 |
Development of a rat model for studying blast-induced traumatic brain injury.
Topics: Animals; Apnea; Blast Injuries; Brain; Brain Edema; Brain Injuries; Disease Models, Animal; Electron | 2010 |
Ventilator autocycling and delayed recognition of brain death.
Topics: Adult; Aged; Apnea; Brain Death; Brain Injuries; Critical Care; Female; Humans; Male; Middle Aged; R | 2011 |
[How long is resuscitation in severe brain injuries possible?].
Topics: Apnea; Brain Diseases; Brain Injuries; Humans; Resuscitation | 1963 |
A case of prolonged apnoea following cerebral laceration.
Topics: Apnea; Brain; Brain Injuries; Lacerations; Respiration, Artificial; Trachea; Wounds and Injuries | 1955 |
[Schizoid psychosis after respiratory arrest in eunarcon anesthesia; cerebral damages caused by anoxemia].
Topics: Anesthesia; Apnea; Barbiturates; Brain; Brain Injuries; Humans; Psychoses, Substance-Induced; Psycho | 1952 |
Ventilator self-cycling may falsely suggest patient effort during brain death determination.
Topics: Apnea; Artifacts; Brain Death; Brain Injuries; Humans; Predictive Value of Tests; Respiratory Physio | 2005 |
Injury severity determines Purkinje cell loss and microglial activation in the cerebellum after cortical contusion injury.
Topics: Animals; Apnea; Biomarkers; Brain Injuries; Cerebellum; Cerebral Cortex; Disease Models, Animal; Gli | 2007 |
Apnea in an infant: what should I look for?
Topics: Anemia; Apnea; Battered Child Syndrome; Brain Injuries; Cardiopulmonary Resuscitation; Cerebrospinal | 2007 |
Effects of ethanol on respiratory function in traumatic brain injury.
Topics: Alcoholic Intoxication; Analysis of Variance; Animals; Apnea; Blood Pressure; Brain; Brain Injuries; | 1995 |
Apnea testing in suspected brain dead children--physiological and mathematical modelling.
Topics: Adolescent; Analysis of Variance; Apnea; Blood Gas Analysis; Brain Death; Brain Injuries; Child; Chi | 1995 |
Brain death assessment using instant spectral analysis of heart rate variability.
Topics: Adult; Analysis of Variance; Apnea; Autonomic Nervous System; Brain Death; Brain Injuries; Brain Ste | 2002 |
Effects of enriched environment and fluid percussion injury on dendritic arborization within the cerebral cortex of the developing rat.
Topics: Animals; Apnea; Brain Injuries; Cell Size; Cerebral Cortex; Dendrites; Environment; Male; Neuronal P | 2002 |
Predicting the outcome of individual patients in the first week after severe head injury.
Topics: Age Factors; Apnea; Brain Injuries; Disabled Persons; Eye Movements; Humans; Motor Activity; Prognos | 1979 |
Head injury prognosis: calculations from clinical data.
Topics: Apnea; Arousal; Brain Concussion; Brain Injuries; Coma; Humans; Medulla Oblongata; Mesencephalon; Mo | 1979 |
Reversal of incipient brain death from head-injury apnea at the scene of accidents.
Topics: Accidents, Traffic; Apnea; Brain Death; Brain Injuries; Child, Preschool; Female; Humans; Resuscitat | 1979 |
Brain death: I. Angiographic correlation with the radioisotopic bolus technique for evaluation of critical deficit of cerebral blood flow.
Topics: Adolescent; Adult; Apnea; Brain Death; Brain Injuries; Cerebral Angiography; Cerebral Hemorrhage; Ce | 1977 |
[Effect of controlled ventilation on heart rate variability in patients with severe cerebral damage].
Topics: Apnea; Brain Damage, Chronic; Brain Death; Brain Injuries; Coma; Electrocardiography; Heart Rate; Hu | 1990 |
Impedance pneumography for the detection of abnormal breathing patterns associated with brain damage.
Topics: Adolescent; Adult; Apnea; Blood Gas Analysis; Brain Injuries; Brain Neoplasms; Electrocardiography; | 1972 |
Respiration and the cerebrospinal fluid in experimental cerebral concussion.
Topics: Animals; Apnea; Brain Injuries; Carbon Dioxide; Cerebrospinal Fluid; Electrocardiography; Haplorhini | 1970 |