apnea has been researched along with Alexander Disease in 1 studies
Apnea: A transient absence of spontaneous respiration.
Alexander Disease: Rare leukoencephalopathy with infantile-onset accumulation of Rosenthal fibers in the subpial, periventricular, and subependymal zones of the brain. Rosenthal fibers are GLIAL FIBRILLARY ACIDIC PROTEIN aggregates found in ASTROCYTES. Juvenile- and adult-onset types show progressive atrophy of the lower brainstem instead. De novo mutations in the GFAP gene are associated with the disease with propensity for paternal inheritance.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alexander disease is a rare, sporadic leukoencephalopathy characterized by white-matter abnormalities with frontal predominance and, as a rule, clinically associated with megalencephaly, seizures, spasticity, and psychomotor deterioration." | 1.33 | Unusual diagnosis in a child suffering from juvenile Alexander disease: clinical and imaging report. ( Bernardi, B; Bracceschi, R; Colonnelli, MC; Errani, A; Franzoni, E; Garone, C; Malaspina, E; Moscano, FC; Salomons, GS; Sarajlija, J; Van der Knaap, MS; Zimmerman, RA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franzoni, E | 1 |
| Van der Knaap, MS | 1 |
| Errani, A | 1 |
| Colonnelli, MC | 1 |
| Bracceschi, R | 1 |
| Malaspina, E | 1 |
| Moscano, FC | 1 |
| Garone, C | 1 |
| Sarajlija, J | 1 |
| Zimmerman, RA | 1 |
| Salomons, GS | 1 |
| Bernardi, B | 1 |
1 other study available for apnea and Alexander Disease
| Article | Year |
|---|---|
Unusual diagnosis in a child suffering from juvenile Alexander disease: clinical and imaging report.
Topics: Adolescent; Age of Onset; Alexander Disease; Anorexia; Apnea; Brain; Brain Stem; Child; Deglutition | 2006 |