Page last updated: 2024-10-31
apnea and Aging
apnea has been researched along with Aging in 62 studies
Apnea: A transient absence of spontaneous respiration.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The analysis suggests that, if it is assumed that the statistical models used are equally valid over the full range of ages considered and that the average rate of apnea reported across the studies analyzed is accurate and representative of actual rates in all institutions, the probability of apnea in nonanemic infants free of recovery-room apnea is not less than 5%, with 95% statistical confidence until postconceptual age was 48 weeks with gestational age 35 weeks." | 9.08 | Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. ( Coté, CJ; Downes, JJ; Kurth, CD; Malviya, SV; Warner, LO; Welborn, LG; Zaslavsky, A, 1995) |
| "Methylxanthine therapy reduces the frequency of apnea and the need for mechanical ventilation." | 8.82 | Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial. ( Schmidt, B, 2005) |
| " MSNA (microneurography) was measured at baseline and during maximal voluntary end-inspiratory (EI) and end-expiratory (EE) apneas." | 7.83 | Effects of aging and coronary artery disease on sympathetic neural recruitment strategies during end-inspiratory and end-expiratory apnea. ( Badrov, MB; Lalande, S; Olver, TD; Shoemaker, JK; Suskin, N, 2016) |
| " PRKO mice exhibited similar levels of minute ventilation during non-REM and REM sleep, and higher frequencies of sighs and post-sigh apneas during non-REM sleep compared to WT." | 7.80 | The nuclear progesterone receptor reduces post-sigh apneas during sleep and increases the ventilatory response to hypercapnia in adult female mice. ( Boukari, R; Joseph, V; Laouafa, S; Lavoie, R; Marcouiller, F, 2014) |
| " In 10 young (26 ± 1 yr) and 11 older (67 ± 2 yr) subjects, we quantified acute hemodynamic responses to three sympathoexcitatory stimuli: local cooling of the forehead, cold pressor test (CPT), and voluntary apnea." | 7.79 | Effect of healthy aging on renal vascular responses to local cooling and apnea. ( Mast, JL; Muller, MD; Patel, HM; Sinoway, LI, 2013) |
| "Both AR and NAR are risk factors for a high apnea-hypopnea index, and both can predispose to sleep apnea." | 7.75 | Allergic and nonallergic rhinitis: the threat for obstructive sleep apnea. ( Ekici, M; Kalpaklioğlu, AF; Kavut, AB, 2009) |
| "During periods of regular breathing, heart rate is slower and more variable in healthy (no history of respiratory distress syndrome) prematurely born infants with persistent apnea, relative to full-term control infants of comparable post-conceptional ages." | 7.70 | Developmental patterns of heart rate and variability in infants with persistent apnea of infancy. ( Harper, RM; Henslee, JA; Schechtman, VL, 1998) |
| " At 40 weeks post-conception, prematurely-born infants with apnea of prematurity showed higher heart rates and reduced heart rate variability than did full-term neonates." | 7.69 | Developmental patterns of heart rate and variability in prematurely-born infants with apnea of prematurity. ( Harper, RM; Henslee, JA; Lee, MY; Schechtman, VL, 1997) |
| " Swallowing-related apnea time (SAT) was measured during "dry" and "wet" swallowing in 84 adults without dysphagia to examine if age-related variation of SAT corresponded to changes in deglutition dynamics due to aging and to determine possible significance." | 7.69 | Factors that affect swallowing-related apnea times in humans. ( Komiyama, S; Miyazaki, H; Yamashita, H, 1994) |
| " The laryngeal chemoreflex-induced apnea was shortened in the piglet group pretreated with water i." | 7.69 | Beta-endorphin may be a mediator of apnea induced by the laryngeal chemoreflex in piglets. ( Oyasaeter, S; Reichelt, KL; Rognum, TO; Saugstad, OD; Stoltenberg, L; Storm, H, 1995) |
| "The maturation of the process of spontaneous recovery from hypoxic apnea by gasping (autoresuscitation) was characterized in adult, weanling (18-22 d), and infant (5 and 10 d) BALB/c mice." | 7.68 | Maturation of cardiorespiratory interactions in spontaneous recovery from hypoxic apnea (autoresuscitation). ( Gershan, WM; Jacobi, MS; Thach, BT, 1990) |
| " Three groups were examined: 17 were of postconceptual age greater than or equal to 37 weeks, 16 were postconceptual age less than or equal to 35 weeks without apnea and 10 were of postconceptual age less than or equal to 35 weeks with apnea." | 7.68 | Cerebrospinal fluid and plasma beta-endorphin-like immunoreactivity in full-term neonates and in preterm neonates with and without apnea of prematurity. ( Arthur-Smith, A; Bors, Z; Herman, BH; Kammerman, LA; MacDonald, MG, 1990) |
| "The mechanism of failure of autoresuscitation from hypoxic apnea in 17- to 23-day-old (weanling) Swiss Webster related/J mice was investigated by recording electrocardiogram (ECG) and ventilation in adult, weanling, and 11-day-old mice." | 7.68 | Mechanism of failure of recovery from hypoxic apnea by gasping in 17- to 23-day-old mice. ( Gershan, WM; Jacobi, MS; Thach, BT, 1991) |
| "The effect of maturation and motor activity on recovery from hypoxic apnea by gasping (autoresuscitation) was investigated in Swiss Webster mice and a SW-related strain." | 7.67 | Effect of maturation on spontaneous recovery from hypoxic apnea by gasping. ( Jacobi, MS; Thach, BT, 1989) |
| "The sleep state characteristics of infant sleep apnea were studied in 36 twins examined by polygraphy at 40, 44, and 52 weeks after conception." | 7.65 | The sleep state characteristics of apnea during infancy. ( Fineberg, N; Gould, JB; James, O; Lee, AF; Sander, L; Teager, H, 1977) |
| "Caffeine half-life was greatly increased in two infants who had cholestatic hepatitis secondary to prolonged parenteral alimentation and one infant who was breast-fed exclusively." | 5.27 | Maturational changes of caffeine concentrations and disposition in infancy during maintenance therapy for apnea of prematurity: influence of gestational age, hepatic disease, and breast-feeding. ( Billon, B; Le Guennec, JC; Paré, C, 1985) |
| " Older children had a longer duration of apnea than infants, 331 vs 180 s (P < 0." | 5.14 | The effect of age on the dose of remifentanil for tracheal intubation in infants and children. ( Ansermino, JM; Brant, R; Hume-Smith, H; Malherbe, S; McCormack, J; Mehta, D; Montgomery, C, 2010) |
| "The analysis suggests that, if it is assumed that the statistical models used are equally valid over the full range of ages considered and that the average rate of apnea reported across the studies analyzed is accurate and representative of actual rates in all institutions, the probability of apnea in nonanemic infants free of recovery-room apnea is not less than 5%, with 95% statistical confidence until postconceptual age was 48 weeks with gestational age 35 weeks." | 5.08 | Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. ( Coté, CJ; Downes, JJ; Kurth, CD; Malviya, SV; Warner, LO; Welborn, LG; Zaslavsky, A, 1995) |
| "While diving, seals are exposed to apnea-induced hypoxemia and repetitive cycles of ischemia/reperfusion." | 4.88 | Coping with physiological oxidative stress: a review of antioxidant strategies in seals. ( Elsner, R; Ortiz, RM; Vázquez-Medina, JP; Zenteno-Savín, T, 2012) |
| "Methylxanthine therapy reduces the frequency of apnea and the need for mechanical ventilation." | 4.82 | Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial. ( Schmidt, B, 2005) |
| " However, the rapid onset of drug effect may be accompanied by rapid onset of adverse events such as apnea and muscle rigidity." | 4.80 | The role of newer opioids in geriatric anesthesia. ( Shafer, SL, 1998) |
| " One group of neonates at high risk for SIDS includes those who develop apnea secondary to gastroesophageal reflux (GER)." | 4.78 | Effects of acid on the larynx of the maturing rabbit and their possible significance to the sudden infant death syndrome. ( Wetmore, RF, 1993) |
| " Although there is some evidence that longer apnea can be elicited in the neonate than in the adult, the use of anesthesia, which may more strongly depress respiration in the young, complicates the issue." | 4.76 | Function of the larynx in the fetus and newborn. ( Harding, R, 1984) |
| " However, neonatal A1R(-/-) mice appeared to have more frequently periods of apnea during hypoxia and in the post-hypoxic control period." | 3.83 | The in vivo respiratory phenotype of the adenosine A1 receptor knockout mouse. ( Buehler, P; Georgieff, M; Heitzmann, D; Schweda, F; Thomas, J; Warth, R, 2016) |
| " MSNA (microneurography) was measured at baseline and during maximal voluntary end-inspiratory (EI) and end-expiratory (EE) apneas." | 3.83 | Effects of aging and coronary artery disease on sympathetic neural recruitment strategies during end-inspiratory and end-expiratory apnea. ( Badrov, MB; Lalande, S; Olver, TD; Shoemaker, JK; Suskin, N, 2016) |
| " PRKO mice exhibited similar levels of minute ventilation during non-REM and REM sleep, and higher frequencies of sighs and post-sigh apneas during non-REM sleep compared to WT." | 3.80 | The nuclear progesterone receptor reduces post-sigh apneas during sleep and increases the ventilatory response to hypercapnia in adult female mice. ( Boukari, R; Joseph, V; Laouafa, S; Lavoie, R; Marcouiller, F, 2014) |
| " In 10 young (26 ± 1 yr) and 11 older (67 ± 2 yr) subjects, we quantified acute hemodynamic responses to three sympathoexcitatory stimuli: local cooling of the forehead, cold pressor test (CPT), and voluntary apnea." | 3.79 | Effect of healthy aging on renal vascular responses to local cooling and apnea. ( Mast, JL; Muller, MD; Patel, HM; Sinoway, LI, 2013) |
| "We measured the duration of apnea induced by sustained end-inspiratory lung inflation (the Hering Breuer Reflex, HBR) in unanesthetized infant rat pups aged 4 days (P4) to P20 at body temperatures of 32°C and 36°C." | 3.79 | Influence of age, body temperature, GABAA receptor inhibition and caffeine on the Hering-Breuer inflation reflex in unanesthetized rat pups. ( Arnal, AV; Bartlett, D; Gore, JL; Leiter, JC; Rudkin, A, 2013) |
| " These big augmented breaths in infants are often followed by apnea and hypoventilation likely secondary to the increased activity of the peripheral chemoreceptors present in neonates." | 3.75 | Morphology of sighs and their role in the control of breathing in preterm infants, term infants and adults. ( Alvaro, RE; Khalil, M; Kwiatkowski, K; Qureshi, M, 2009) |
| "Both AR and NAR are risk factors for a high apnea-hypopnea index, and both can predispose to sleep apnea." | 3.75 | Allergic and nonallergic rhinitis: the threat for obstructive sleep apnea. ( Ekici, M; Kalpaklioğlu, AF; Kavut, AB, 2009) |
| "Seventy-six normal subjects (40 men) without sleep apnea or periodic limb movements of sleep, aged 18 to 70 years, slept in the sleep laboratory for 1 or more nights." | 3.74 | EEG arousal norms by age. ( Arand, DL; Bonnet, MH, 2007) |
| " Studies in which cough and other airway protective responses have been stimulated by introducing a small bolus of water or saline into the pharynx of sleeping infants have found that the predominant responses are swallowing, apnea and laryngeal closure." | 3.74 | Maturation of cough and other reflexes that protect the fetal and neonatal airway. ( Thach, BT, 2007) |
| "Apnea and respiratory failure often occur in infants with pulmonary disease." | 3.73 | Postnatal development of right atrial injection of capsaicin-induced apneic response in rats. ( Wang, R; Xu, F, 2006) |
| " Swallow apnea increased with age (5 ml of water r = 0." | 3.73 | Swallow respiratory patterns and aging: presbyphagia or dysphagia? ( Drinnan, MJ; Ford, GA; Leslie, P; Wilson, JA, 2005) |
| " Differences in apnea duration and apnea offset occurred with advanced age." | 3.73 | Breathing and swallowing dynamics across the adult lifespan. ( Brodsky, MB; Ford, CL; Heffner, J; Martin-Harris, B; Michel, Y; Walters, B, 2005) |
| " Significant lactate signals were found in seven patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) during sleep periods, and none during periods of arousal." | 3.72 | Age-related changes in cerebral lactate metabolism in sleep-disordered breathing. ( Higami, S; Inoue, Y; Kamba, M; Suto, Y, 2003) |
| " Apneas were frequent at P(0) (occupying 29 +/- 6% of total time) but rare by P(3) (5 +/- 2% of total time)." | 3.70 | Development of the ventilatory response to hypoxia in Swiss CD-1 mice. ( Adams, BM; Funk, GD; Kwok, H; Peebles, KC; Robinson, DM, 2000) |
| "During periods of regular breathing, heart rate is slower and more variable in healthy (no history of respiratory distress syndrome) prematurely born infants with persistent apnea, relative to full-term control infants of comparable post-conceptional ages." | 3.70 | Developmental patterns of heart rate and variability in infants with persistent apnea of infancy. ( Harper, RM; Henslee, JA; Schechtman, VL, 1998) |
| " Plasma concentrations at terminal apnea were higher for ropivacaine than for bupivacaine at all ages, and were higher in infants than in older rats." | 3.70 | Sciatic nerve blockade in infant, adolescent, and adult rats: a comparison of ropivacaine with bupivacaine. ( Berde, CB; Hu, D; Kohane, DS; Rifai, N; Sankar, WN; Shubina, M, 1998) |
| " the apnea-bradycardia-hypotension triad) is mediated through a reflex central cholinergic pathway." | 3.69 | Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves. ( Amory, H; Desmecht, DJ; Lekeux, PM; Linden, AS, 1996) |
| " After a postsurgery recovery of at least 7 days, we studied all animals to detect the presence of apnea and the consequences of it, if any." | 3.69 | Age-dependent vulnerability to carotid chemodenervation in piglets. ( Côté, A; Meehan, B; Porras, H, 1996) |
| " Swallowing-related apnea time (SAT) was measured during "dry" and "wet" swallowing in 84 adults without dysphagia to examine if age-related variation of SAT corresponded to changes in deglutition dynamics due to aging and to determine possible significance." | 3.69 | Factors that affect swallowing-related apnea times in humans. ( Komiyama, S; Miyazaki, H; Yamashita, H, 1994) |
| " The laryngeal chemoreflex-induced apnea was shortened in the piglet group pretreated with water i." | 3.69 | Beta-endorphin may be a mediator of apnea induced by the laryngeal chemoreflex in piglets. ( Oyasaeter, S; Reichelt, KL; Rognum, TO; Saugstad, OD; Stoltenberg, L; Storm, H, 1995) |
| " At 40 weeks post-conception, prematurely-born infants with apnea of prematurity showed higher heart rates and reduced heart rate variability than did full-term neonates." | 3.69 | Developmental patterns of heart rate and variability in prematurely-born infants with apnea of prematurity. ( Harper, RM; Henslee, JA; Lee, MY; Schechtman, VL, 1997) |
| " Similarly, duration and efficiency of gasping, a unique mechanism for enhancing survival after anoxia-induced apnea, are also affected by postnatal age." | 3.69 | Characterization and developmental aspects of anoxia-induced gasping in the rat. ( Gozal, D; Gozal, YM; Nuckton, TJ; Torres, JE, 1996) |
| "We recently showed that the glottis is actively closed throughout post-hyperventilation, hypocapnic central apnea in lambs." | 3.69 | Prolonged active glottic closure after barbiturate-induced respiratory arrest in lambs. ( Dalle, D; Diaz, V; Kianicka, I; Leroux, JF; Praud, JP, 1996) |
| "The mechanism of failure of autoresuscitation from hypoxic apnea in 17- to 23-day-old (weanling) Swiss Webster related/J mice was investigated by recording electrocardiogram (ECG) and ventilation in adult, weanling, and 11-day-old mice." | 3.68 | Mechanism of failure of recovery from hypoxic apnea by gasping in 17- to 23-day-old mice. ( Gershan, WM; Jacobi, MS; Thach, BT, 1991) |
| " Three groups were examined: 17 were of postconceptual age greater than or equal to 37 weeks, 16 were postconceptual age less than or equal to 35 weeks without apnea and 10 were of postconceptual age less than or equal to 35 weeks with apnea." | 3.68 | Cerebrospinal fluid and plasma beta-endorphin-like immunoreactivity in full-term neonates and in preterm neonates with and without apnea of prematurity. ( Arthur-Smith, A; Bors, Z; Herman, BH; Kammerman, LA; MacDonald, MG, 1990) |
| "The maturation of the process of spontaneous recovery from hypoxic apnea by gasping (autoresuscitation) was characterized in adult, weanling (18-22 d), and infant (5 and 10 d) BALB/c mice." | 3.68 | Maturation of cardiorespiratory interactions in spontaneous recovery from hypoxic apnea (autoresuscitation). ( Gershan, WM; Jacobi, MS; Thach, BT, 1990) |
| "The effect of maturation and motor activity on recovery from hypoxic apnea by gasping (autoresuscitation) was investigated in Swiss Webster mice and a SW-related strain." | 3.67 | Effect of maturation on spontaneous recovery from hypoxic apnea by gasping. ( Jacobi, MS; Thach, BT, 1989) |
| " Hypoxia did not significantly affect the LAR or apnea duration in animals with only one intact SLN." | 3.67 | Laryngeal chemoreflex: anatomic and physiologic study by use of the superior laryngeal nerve in the piglet. ( Goding, GS; Richardson, MA; Trachy, RE, 1987) |
| "Five neonates (4 premature) and 16 infants (6 prematurely born), 15-588 days old, received caffeine as citrate salt for apnea." | 3.67 | Developmental changes of caffeine elimination in infancy. ( Badoual, J; Carrier, O; d'Athis, P; Moran, C; Olive, G; Pons, G; Rey, E; Richard, MO, 1988) |
| "Theophylline (T) tissue distribution was studied in 11 premature newborns treated with T for prematurity apnea, who had died from severe pathology." | 3.66 | Theophylline distribution in the premature neonate. ( Assael, BM; Bonati, M; Latini, R; Marra, G; Parini, R, 1981) |
| "5%) caused extended apnea." | 3.66 | Laryngeal reflex inhibition of breathing in piglets: influences of anemia and catecholamine depletion. ( Downing, SE; Lee, JC, 1980) |
| "The sleep state characteristics of infant sleep apnea were studied in 36 twins examined by polygraphy at 40, 44, and 52 weeks after conception." | 3.65 | The sleep state characteristics of apnea during infancy. ( Fineberg, N; Gould, JB; James, O; Lee, AF; Sander, L; Teager, H, 1977) |
| "Midazolam pretreatment was associated with a significant reduction in propofol dose requirement in both younger and older patients." | 2.70 | Effect of midazolam pretreatment on induction dose requirements of propofol in combination with fentanyl in younger and older adults. ( Bhaskaran, NC; Claydon, P; Cressey, DM; Reilly, CS, 2001) |
| "It is characterized by infantile seizures refractory to anticonvulsive treatments, microcephaly, delays in mental and motor development, spasticity, ataxia, dysarthria and other paroxysmal neurologic phenomena, often occurring prior to meals." | 2.44 | [Glucose transporter type 1 (GLUT-1) deficiency]. ( Cano, A; Chabrol, B; Ticus, I, 2008) |
| "End-stage renal disease (ESRD) is characterized by resting sympathetic overactivity." | 1.35 | Differential distribution of muscle and skin sympathetic nerve activity in patients with end-stage renal disease. ( Campese, VM; Middlekauff, HR; Nobakht, N; Park, J, 2008) |
| "9 as an end point for pre-oxygenation, we have compared the time taken to achieve this end point and the safe duration of apnoea after induction of anaesthesia following pre-oxygenation in elderly patients and young adults." | 1.30 | End-tidal oxygraphy and safe duration of apnoea in young adults and elderly patients. ( Bhandari, SC; Bhatia, PK; Kumar, Y; Tulsiani, KL, 1997) |
| "Twenty-one subjects had bilateral choanal atresia/stenosis; 12 had unilateral choanal atresia/stenosis, and eight who were referred with suspected choanal atresia had a simple inflammatory nasal obstruction." | 1.27 | Clinical manifestations of choanal atresia in infancy. ( Colarossi, G; Cozzi, F; Madonna, L; Rosati, D; Steiner, M, 1988) |
| "Caffeine half-life was greatly increased in two infants who had cholestatic hepatitis secondary to prolonged parenteral alimentation and one infant who was breast-fed exclusively." | 1.27 | Maturational changes of caffeine concentrations and disposition in infancy during maintenance therapy for apnea of prematurity: influence of gestational age, hepatic disease, and breast-feeding. ( Billon, B; Le Guennec, JC; Paré, C, 1985) |
Research
Studies (62)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (25.81) | 18.7374 |
| 1990's | 22 (35.48) | 18.2507 |
| 2000's | 16 (25.81) | 29.6817 |
| 2010's | 8 (12.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Patel, HM | 1 |
| Mast, JL | 1 |
| Sinoway, LI | 1 |
| Muller, MD | 1 |
| Marcouiller, F | 1 |
| Boukari, R | 1 |
| Laouafa, S | 1 |
| Lavoie, R | 1 |
| Joseph, V | 1 |
| Heitzmann, D | 1 |
| Buehler, P | 1 |
| Schweda, F | 1 |
| Georgieff, M | 1 |
| Warth, R | 1 |
| Thomas, J | 1 |
| Badrov, MB | 1 |
| Lalande, S | 1 |
| Olver, TD | 1 |
| Suskin, N | 1 |
| Shoemaker, JK | 1 |
| Sohn, JA | 1 |
| Kim, HS | 1 |
| Oh, J | 1 |
| Cho, JY | 1 |
| Yu, KS | 1 |
| Lee, J | 1 |
| Shin, SH | 1 |
| Lee, JA | 1 |
| Choi, CW | 1 |
| Kim, EK | 1 |
| Kim, BI | 1 |
| Park, EA | 1 |
| Cano, A | 1 |
| Ticus, I | 1 |
| Chabrol, B | 1 |
| Park, J | 1 |
| Campese, VM | 1 |
| Nobakht, N | 1 |
| Middlekauff, HR | 1 |
| Qureshi, M | 1 |
| Khalil, M | 1 |
| Kwiatkowski, K | 1 |
| Alvaro, RE | 1 |
| Kalpaklioğlu, AF | 1 |
| Kavut, AB | 1 |
| Ekici, M | 1 |
| Hume-Smith, H | 1 |
| McCormack, J | 1 |
| Montgomery, C | 1 |
| Brant, R | 1 |
| Malherbe, S | 1 |
| Mehta, D | 1 |
| Ansermino, JM | 1 |
| Vázquez-Medina, JP | 1 |
| Zenteno-Savín, T | 1 |
| Elsner, R | 1 |
| Ortiz, RM | 1 |
| Arnal, AV | 1 |
| Gore, JL | 1 |
| Rudkin, A | 1 |
| Bartlett, D | 1 |
| Leiter, JC | 1 |
| Martin-Harris, B | 2 |
| Brodsky, MB | 2 |
| Price, CC | 1 |
| Michel, Y | 2 |
| Walters, B | 2 |
| Kamba, M | 1 |
| Inoue, Y | 1 |
| Higami, S | 1 |
| Suto, Y | 1 |
| Zabka, AG | 2 |
| Mitchell, GS | 2 |
| Olson, EB | 1 |
| Behan, M | 2 |
| MITOLO, M | 1 |
| MITOLO, V | 1 |
| Leslie, P | 1 |
| Drinnan, MJ | 1 |
| Ford, GA | 1 |
| Wilson, JA | 1 |
| Ford, CL | 1 |
| Heffner, J | 1 |
| Schmidt, B | 1 |
| Wang, R | 1 |
| Xu, F | 1 |
| Thach, BT | 4 |
| Bonnet, MH | 1 |
| Arand, DL | 1 |
| Harding, R | 1 |
| Carse, EA | 1 |
| Wilkinson, AR | 1 |
| Whyte, PL | 1 |
| Henderson-Smart, DJ | 1 |
| Johnson, P | 1 |
| Bonati, M | 1 |
| Latini, R | 1 |
| Marra, G | 1 |
| Assael, BM | 1 |
| Parini, R | 1 |
| Lee, JC | 1 |
| Downing, SE | 1 |
| Storm, H | 1 |
| Stoltenberg, L | 1 |
| Oyasaeter, S | 1 |
| Saugstad, OD | 1 |
| Rognum, TO | 1 |
| Reichelt, KL | 1 |
| Fisher, DM | 1 |
| Coté, CJ | 1 |
| Zaslavsky, A | 1 |
| Downes, JJ | 1 |
| Kurth, CD | 1 |
| Welborn, LG | 1 |
| Warner, LO | 1 |
| Malviya, SV | 1 |
| Patel, R | 1 |
| Lenczyk, M | 1 |
| Hannallah, RS | 1 |
| McGill, WA | 1 |
| Wetmore, RF | 1 |
| Wolsink, JG | 1 |
| Berkenbosch, A | 1 |
| DeGoede, J | 1 |
| Olievier, CN | 1 |
| Wallois, F | 1 |
| Khater-Boidin, J | 1 |
| Dusaussoy, F | 1 |
| Duron, B | 1 |
| Linden, AS | 1 |
| Desmecht, DJ | 1 |
| Amory, H | 1 |
| Lekeux, PM | 1 |
| Côté, A | 1 |
| Porras, H | 1 |
| Meehan, B | 1 |
| Praud, JP | 1 |
| Kianicka, I | 1 |
| Diaz, V | 1 |
| Leroux, JF | 1 |
| Dalle, D | 1 |
| Gozal, D | 1 |
| Torres, JE | 1 |
| Gozal, YM | 1 |
| Nuckton, TJ | 1 |
| Bhatia, PK | 1 |
| Bhandari, SC | 1 |
| Tulsiani, KL | 1 |
| Kumar, Y | 1 |
| Henslee, JA | 2 |
| Schechtman, VL | 2 |
| Lee, MY | 1 |
| Harper, RM | 2 |
| Shafer, SL | 1 |
| Kohane, DS | 1 |
| Sankar, WN | 1 |
| Shubina, M | 1 |
| Hu, D | 1 |
| Rifai, N | 1 |
| Berde, CB | 1 |
| Tateishi, T | 1 |
| Asoh, M | 1 |
| Yamaguchi, A | 1 |
| Yoda, T | 1 |
| Okano, YJ | 1 |
| Koitabashi, Y | 1 |
| Kobayashi, S | 1 |
| Robinson, DM | 1 |
| Kwok, H | 1 |
| Adams, BM | 1 |
| Peebles, KC | 1 |
| Funk, GD | 1 |
| Cressey, DM | 1 |
| Claydon, P | 1 |
| Bhaskaran, NC | 1 |
| Reilly, CS | 1 |
| Miyazaki, H | 1 |
| Yamashita, H | 1 |
| Komiyama, S | 1 |
| Gould, JB | 1 |
| Lee, AF | 1 |
| James, O | 1 |
| Sander, L | 1 |
| Teager, H | 1 |
| Fineberg, N | 1 |
| Buchanan, N | 1 |
| Shaker, R | 1 |
| Li, Q | 1 |
| Ren, J | 1 |
| Townsend, WF | 1 |
| Dodds, WJ | 1 |
| Martin, BJ | 1 |
| Kern, MK | 1 |
| Rynders, A | 1 |
| Jacobi, MS | 3 |
| Gershan, WM | 2 |
| MacDonald, MG | 1 |
| Herman, BH | 1 |
| Kammerman, LA | 1 |
| Bors, Z | 1 |
| Arthur-Smith, A | 1 |
| Lainé-Cessac, P | 1 |
| Turcant, A | 1 |
| Allain, P | 1 |
| Goding, GS | 1 |
| Richardson, MA | 1 |
| Trachy, RE | 1 |
| Pons, G | 1 |
| Carrier, O | 1 |
| Richard, MO | 1 |
| Rey, E | 1 |
| d'Athis, P | 1 |
| Moran, C | 1 |
| Badoual, J | 1 |
| Olive, G | 1 |
| Cozzi, F | 1 |
| Steiner, M | 1 |
| Rosati, D | 1 |
| Madonna, L | 1 |
| Colarossi, G | 1 |
| Southall, DP | 1 |
| Alexander, JR | 1 |
| Stebbens, VA | 1 |
| Taylor, VG | 1 |
| Janczynski, RE | 1 |
| Le Guennec, JC | 1 |
| Billon, B | 1 |
| Paré, C | 1 |
| Nixon, P | 1 |
| Bethell, HJ | 1 |
| Farber, JP | 1 |
Clinical Trials (6)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths in Neonate: Effect on Carbon Dioxide Level[NCT05682937] | 50 participants (Anticipated) | Interventional | 2023-01-12 | Enrolling by invitation | |||
| Study to Evaluate the Optimal Dose of Remifentanil Required to Ensure Apnoea During Magnetic Resonance Imaging of the Heart Under General Anaesthesia[NCT02481791] | Phase 3 | 35 participants (Anticipated) | Interventional | 2015-07-31 | Recruiting | ||
| Experienced Breacher Study: Evaluation of the Effects From Chronic Exposure to Low-Level Blast[NCT01524822] | 66 participants (Actual) | Observational | 2012-07-30 | Completed | |||
| Apneic Oxygenation to Prevent Oxygen Desaturation During Intubation in the NICU[NCT05451953] | 110 participants (Anticipated) | Interventional | 2022-07-21 | Recruiting | |||
| A Randomized, Placebo-Controlled Assessment of Lansoprazole 30 mg Bid in the Treatment of Gastroesophageal Reflux Associated With Laryngitis[NCT00369265] | Phase 4 | 18 participants (Actual) | Interventional | 2006-08-31 | Terminated (stopped due to Pharmaceutical company purchased by another company and funding was terminated.) | ||
| End-tidal Oxygen Can Reliably Predict the Arterial Partial Pressure of Oxygen Among Emergency Department Patients Undergoing Rapid Sequence Intubation[NCT03842306] | 75 participants (Actual) | Observational | 2017-10-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
7 reviews available for apnea and Aging
| Article | Year |
|---|---|
[Glucose transporter type 1 (GLUT-1) deficiency].
Topics: Aging; Apnea; Blood-Brain Barrier; Brain Diseases; Developmental Disabilities; Glucose Transporter T | 2008 |
Coping with physiological oxidative stress: a review of antioxidant strategies in seals.
Topics: Adaptation, Physiological; Aging; Animals; Antioxidants; Apnea; Diving; Fasting; Hypoxia; Oxidative | 2012 |
Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial.
Topics: Aging; Apnea; Blindness; Cerebral Palsy; Cognition Disorders; Deafness; Follow-Up Studies; Humans; I | 2005 |
Function of the larynx in the fetus and newborn.
Topics: Aging; Airway Resistance; Animals; Animals, Newborn; Apnea; Body Fluids; Cardiovascular Physiologica | 1984 |
Effects of acid on the larynx of the maturing rabbit and their possible significance to the sudden infant death syndrome.
Topics: Aging; Airway Obstruction; Animals; Apnea; Female; Gastroesophageal Reflux; Humans; Hydrochloric Aci | 1993 |
The role of newer opioids in geriatric anesthesia.
Topics: Adult; Aged; Aged, 80 and over; Aging; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, | 1998 |
Clinical pharmacology of theophylline.
Topics: Administration, Oral; Adolescent; Adult; Aging; Apnea; Arterioles; Biological Availability; Bronchia | 1979 |
Trials
3 trials available for apnea and Aging
| Article | Year |
|---|---|
The effect of age on the dose of remifentanil for tracheal intubation in infants and children.
Topics: Adjuvants, Anesthesia; Aging; Anesthetics, Intravenous; Apnea; Blood Gas Analysis; Child, Preschool; | 2010 |
Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis.
Topics: Aging; Analysis of Variance; Anemia; Anesthesia; Apnea; Birth Weight; Hernia, Inguinal; Humans; Infa | 1995 |
Effect of midazolam pretreatment on induction dose requirements of propofol in combination with fentanyl in younger and older adults.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Aging; Analysis of Variance; Anesthetics, Intravenou | 2001 |
Other Studies
52 other studies available for apnea and Aging
| Article | Year |
|---|---|
Effect of healthy aging on renal vascular responses to local cooling and apnea.
Topics: Adult; Aged; Aging; Apnea; Arterial Pressure; Cold Temperature; Cross-Over Studies; Female; Forehead | 2013 |
The nuclear progesterone receptor reduces post-sigh apneas during sleep and increases the ventilatory response to hypercapnia in adult female mice.
Topics: Aging; Animals; Apnea; Cell Nucleus; Electroencephalography; Electromyography; Female; Hypercapnia; | 2014 |
The in vivo respiratory phenotype of the adenosine A1 receptor knockout mouse.
Topics: Aging; Animals; Animals, Newborn; Apnea; Blood Gas Analysis; Disease Models, Animal; Female; Hyperca | 2016 |
Effects of aging and coronary artery disease on sympathetic neural recruitment strategies during end-inspiratory and end-expiratory apnea.
Topics: Action Potentials; Adult; Age Factors; Aged; Aging; Apnea; Arterial Pressure; Blood Pressure; Breath | 2016 |
Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants.
Topics: Aging; Apnea; Bronchodilator Agents; Cytochrome P-450 CYP1A2; Female; Genotype; Gestational Age; Hum | 2017 |
Differential distribution of muscle and skin sympathetic nerve activity in patients with end-stage renal disease.
Topics: Adult; Aging; Apnea; Baroreflex; Blood Pressure; Body Mass Index; Electrophysiology; Female; Heart R | 2008 |
Morphology of sighs and their role in the control of breathing in preterm infants, term infants and adults.
Topics: Adult; Aging; Apnea; Humans; Hypoventilation; Infant, Newborn; Infant, Premature; Movement; Respirat | 2009 |
Allergic and nonallergic rhinitis: the threat for obstructive sleep apnea.
Topics: Adult; Aging; Apnea; Asthma; Body Mass Index; Disorders of Excessive Somnolence; Female; Humans; Mal | 2009 |
Influence of age, body temperature, GABAA receptor inhibition and caffeine on the Hering-Breuer inflation reflex in unanesthetized rat pups.
Topics: Aging; Animals; Animals, Newborn; Apnea; Body Temperature; Caffeine; Central Nervous System Stimulan | 2013 |
Temporal coordination of pharyngeal and laryngeal dynamics with breathing during swallowing: single liquid swallows.
Topics: Adult; Aging; Apnea; Barium Sulfate; Black People; Deglutition; Female; Humans; Larynx; Male; Pharyn | 2003 |
Age-related changes in cerebral lactate metabolism in sleep-disordered breathing.
Topics: Adult; Aged; Aging; Apnea; Body Mass Index; Cerebral Cortex; Female; Humans; Lactic Acid; Magnetic R | 2003 |
Selected contribution: chronic intermittent hypoxia enhances respiratory long-term facilitation in geriatric female rats.
Topics: Aging; Algorithms; Animals; Apnea; Blood Pressure; Caloric Restriction; Carbon Dioxide; Estrous Cycl | 2003 |
[Training in the test of maximum voluntary apnea in aged subjects; biologico-statistical study].
Topics: Aging; Apnea; Humans; Pulmonary Ventilation; Respiratory Function Tests | 1956 |
Ageing and gonadectomy have similar effects on hypoglossal long-term facilitation in male Fischer rats.
Topics: Aging; Animals; Apnea; Carbon Dioxide; Hypoglossal Nerve; Hypoxia; Long-Term Potentiation; Male; Orc | 2005 |
Swallow respiratory patterns and aging: presbyphagia or dysphagia?
Topics: Adult; Age Factors; Aged; Aging; Apnea; Cohort Studies; Deglutition; Deglutition Disorders; Diagnosi | 2005 |
Breathing and swallowing dynamics across the adult lifespan.
Topics: Adult; Age Factors; Aged; Aging; Apnea; Deglutition; Female; Fluoroscopy; Humans; Larynx; Male; Midd | 2005 |
Postnatal development of right atrial injection of capsaicin-induced apneic response in rats.
Topics: Aging; Animals; Animals, Newborn; Apnea; Capsaicin; Exhalation; Heart Atria; Injections; Lung Volume | 2006 |
Maturation of cough and other reflexes that protect the fetal and neonatal airway.
Topics: Aging; Animals; Apnea; Chemoreceptor Cells; Cough; Deglutition; Fetal Development; Fetus; Humans; In | 2007 |
EEG arousal norms by age.
Topics: Adolescent; Age Factors; Aged; Aging; Apnea; Arousal; Electroencephalography; Female; Humans; Male; | 2007 |
Oxygen and carbon dioxide tensions, breathing and heart rate in normal infants during the first six months of life.
Topics: Aging; Apnea; Carbon Dioxide; Electrocardiography; Electroencephalography; Female; Heart Rate; Human | 1981 |
Theophylline distribution in the premature neonate.
Topics: Aging; Animals; Animals, Newborn; Apnea; Blood-Brain Barrier; Female; Gestational Age; Guinea Pigs; | 1981 |
Laryngeal reflex inhibition of breathing in piglets: influences of anemia and catecholamine depletion.
Topics: Aging; Anemia, Hypochromic; Animals; Apnea; Electric Stimulation; Female; Laryngeal Nerves; Male; Po | 1980 |
Beta-endorphin may be a mediator of apnea induced by the laryngeal chemoreflex in piglets.
Topics: Aging; Animals; Apnea; beta-Endorphin; Blood Glucose; Body Weight; Cisterna Magna; Female; Hematocri | 1995 |
When is the ex-premature infant no longer at risk for apnea?
Topics: Aging; Anesthesia, General; Apnea; Humans; Infant, Newborn; Infant, Premature; Risk Factors | 1995 |
Age and the onset of desaturation in apnoeic children.
Topics: Adolescent; Aging; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Apnea; Body | 1994 |
Maturation of the ventilatory response to CO2 in the newborn piglet.
Topics: Aging; Animals; Animals, Newborn; Apnea; Blood Pressure; Carbon Dioxide; Hydrogen-Ion Concentration; | 1993 |
Oral stimulations induce apnoea in newborn kittens.
Topics: Aging; Anesthesia; Animals; Animals, Newborn; Apnea; Cats; Decerebrate State; Deglutition; Electric | 1993 |
Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves.
Topics: Aging; Animals; Apnea; Atropine; Bradycardia; Cattle; Cattle Diseases; Cholinergic Agents; Ganglioni | 1996 |
Age-dependent vulnerability to carotid chemodenervation in piglets.
Topics: Aging; Anesthesia; Animals; Animals, Newborn; Apnea; Blood Gas Analysis; Body Temperature; Carotid B | 1996 |
Prolonged active glottic closure after barbiturate-induced respiratory arrest in lambs.
Topics: Abdominal Muscles; Aging; Animals; Animals, Newborn; Apnea; Electrodes, Implanted; Electromyography; | 1996 |
Characterization and developmental aspects of anoxia-induced gasping in the rat.
Topics: Aging; Animals; Apnea; Electrocardiography; Hypoxia; Rats; Rats, Sprague-Dawley; Respiration | 1996 |
End-tidal oxygraphy and safe duration of apnoea in young adults and elderly patients.
Topics: Adult; Aged; Aging; Apnea; Carbon Dioxide; Female; Hemodynamics; Humans; Male; Middle Aged; Monitori | 1997 |
Developmental patterns of heart rate and variability in prematurely-born infants with apnea of prematurity.
Topics: Aging; Apnea; Electrocardiography; Female; Gestational Age; Heart Rate; Humans; Infant, Newborn; Inf | 1997 |
Developmental patterns of heart rate and variability in infants with persistent apnea of infancy.
Topics: Aging; Apnea; Electrocardiography; Gestational Age; Heart Rate; Humans; Infant, Newborn; Infant, Pre | 1998 |
Sciatic nerve blockade in infant, adolescent, and adult rats: a comparison of ropivacaine with bupivacaine.
Topics: Aging; Amides; Anesthetics, Local; Animals; Apnea; Behavior, Animal; Bupivacaine; Dose-Response Rela | 1998 |
Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients.
Topics: Aging; Apnea; Asthma; Child, Preschool; Cytochrome P-450 CYP1A2; Humans; Infant; Infant, Newborn; Th | 1999 |
Development of the ventilatory response to hypoxia in Swiss CD-1 mice.
Topics: Aging; Animals; Animals, Newborn; Apnea; Hypoxia; Mice; Pulmonary Ventilation; Respiration | 2000 |
Factors that affect swallowing-related apnea times in humans.
Topics: Adult; Age Factors; Aged; Aging; Apnea; Deglutition; Female; Humans; Male; Middle Aged; Time Factors | 1994 |
The sleep state characteristics of apnea during infancy.
Topics: Aging; Apnea; Diseases in Twins; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant, P | 1977 |
Coordination of deglutition and phases of respiration: effect of aging, tachypnea, bolus volume, and chronic obstructive pulmonary disease.
Topics: Adult; Aged; Aged, 80 and over; Aging; Apnea; Deglutition; Humans; Lung Diseases, Obstructive; Middl | 1992 |
Mechanism of failure of recovery from hypoxic apnea by gasping in 17- to 23-day-old mice.
Topics: Aging; Airway Obstruction; Animals; Apnea; Electrocardiography; Heart Rate; Hypoxia; Mice; Mice, Inb | 1991 |
Cerebrospinal fluid and plasma beta-endorphin-like immunoreactivity in full-term neonates and in preterm neonates with and without apnea of prematurity.
Topics: Aging; Apnea; beta-Endorphin; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; M | 1990 |
Maturation of cardiorespiratory interactions in spontaneous recovery from hypoxic apnea (autoresuscitation).
Topics: Aging; Animals; Apnea; Cardiovascular System; Heart Rate; Hypoxia; Mice; Mice, Inbred BALB C; Oxygen | 1990 |
Effect of maturation on spontaneous recovery from hypoxic apnea by gasping.
Topics: Aging; Animals; Apnea; Electromyography; Hypoxia; Mice; Mice, Inbred Strains; Motor Activity; Muscle | 1989 |
Automated determination of cholinesterase activity in plasma and erythrocytes by flow-injection analysis, and application to identify subjects sensitive to succinylcholine.
Topics: Adult; Aging; Anesthesia; Apnea; Autoanalysis; Cholinesterases; Erythrocytes; Female; Humans; Male; | 1989 |
Laryngeal chemoreflex: anatomic and physiologic study by use of the superior laryngeal nerve in the piglet.
Topics: Aging; Animals; Apnea; Blood Pressure; Chemoreceptor Cells; Horseradish Peroxidase; Laryngeal Mucosa | 1987 |
Developmental changes of caffeine elimination in infancy.
Topics: Aging; Apnea; Caffeine; Drug Administration Schedule; Gestational Age; Half-Life; Humans; Infant; In | 1988 |
Clinical manifestations of choanal atresia in infancy.
Topics: Aging; Airway Obstruction; Apnea; Autonomic Nervous System Diseases; Child, Preschool; Choanal Atres | 1988 |
Cardiorespiratory patterns in siblings of babies with sudden infant death syndrome.
Topics: Aging; Apnea; Electrocardiography; Family; Follow-Up Studies; Heart Rate; Humans; Infant, Newborn; P | 1987 |
Maturational changes of caffeine concentrations and disposition in infancy during maintenance therapy for apnea of prematurity: influence of gestational age, hepatic disease, and breast-feeding.
Topics: Aging; Apnea; Breast Feeding; Caffeine; Cholestasis; Citrates; Drug Combinations; Gestational Age; H | 1985 |
Letter: Presentation of myocardial infarction.
Topics: Aging; Angina Pectoris; Apnea; Blood Pressure; Electrocardiography; Fatigue; Humans; Myocardial Infa | 1974 |
Development of pulmonary reflexes and pattern of breathing in Virginia opossum.
Topics: Aging; Animals; Apnea; Asphyxia; Diaphragm; Electromyography; Humans; Hypercapnia; Hypoxia; Intercos | 1972 |