Page last updated: 2024-10-31

apnea and Aging

apnea has been researched along with Aging in 62 studies

Apnea: A transient absence of spontaneous respiration.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The analysis suggests that, if it is assumed that the statistical models used are equally valid over the full range of ages considered and that the average rate of apnea reported across the studies analyzed is accurate and representative of actual rates in all institutions, the probability of apnea in nonanemic infants free of recovery-room apnea is not less than 5%, with 95% statistical confidence until postconceptual age was 48 weeks with gestational age 35 weeks."9.08Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. ( Coté, CJ; Downes, JJ; Kurth, CD; Malviya, SV; Warner, LO; Welborn, LG; Zaslavsky, A, 1995)
"Methylxanthine therapy reduces the frequency of apnea and the need for mechanical ventilation."8.82Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial. ( Schmidt, B, 2005)
" MSNA (microneurography) was measured at baseline and during maximal voluntary end-inspiratory (EI) and end-expiratory (EE) apneas."7.83Effects of aging and coronary artery disease on sympathetic neural recruitment strategies during end-inspiratory and end-expiratory apnea. ( Badrov, MB; Lalande, S; Olver, TD; Shoemaker, JK; Suskin, N, 2016)
" PRKO mice exhibited similar levels of minute ventilation during non-REM and REM sleep, and higher frequencies of sighs and post-sigh apneas during non-REM sleep compared to WT."7.80The nuclear progesterone receptor reduces post-sigh apneas during sleep and increases the ventilatory response to hypercapnia in adult female mice. ( Boukari, R; Joseph, V; Laouafa, S; Lavoie, R; Marcouiller, F, 2014)
" In 10 young (26 ± 1 yr) and 11 older (67 ± 2 yr) subjects, we quantified acute hemodynamic responses to three sympathoexcitatory stimuli: local cooling of the forehead, cold pressor test (CPT), and voluntary apnea."7.79Effect of healthy aging on renal vascular responses to local cooling and apnea. ( Mast, JL; Muller, MD; Patel, HM; Sinoway, LI, 2013)
"Both AR and NAR are risk factors for a high apnea-hypopnea index, and both can predispose to sleep apnea."7.75Allergic and nonallergic rhinitis: the threat for obstructive sleep apnea. ( Ekici, M; Kalpaklioğlu, AF; Kavut, AB, 2009)
"During periods of regular breathing, heart rate is slower and more variable in healthy (no history of respiratory distress syndrome) prematurely born infants with persistent apnea, relative to full-term control infants of comparable post-conceptional ages."7.70Developmental patterns of heart rate and variability in infants with persistent apnea of infancy. ( Harper, RM; Henslee, JA; Schechtman, VL, 1998)
" At 40 weeks post-conception, prematurely-born infants with apnea of prematurity showed higher heart rates and reduced heart rate variability than did full-term neonates."7.69Developmental patterns of heart rate and variability in prematurely-born infants with apnea of prematurity. ( Harper, RM; Henslee, JA; Lee, MY; Schechtman, VL, 1997)
" Swallowing-related apnea time (SAT) was measured during "dry" and "wet" swallowing in 84 adults without dysphagia to examine if age-related variation of SAT corresponded to changes in deglutition dynamics due to aging and to determine possible significance."7.69Factors that affect swallowing-related apnea times in humans. ( Komiyama, S; Miyazaki, H; Yamashita, H, 1994)
" The laryngeal chemoreflex-induced apnea was shortened in the piglet group pretreated with water i."7.69Beta-endorphin may be a mediator of apnea induced by the laryngeal chemoreflex in piglets. ( Oyasaeter, S; Reichelt, KL; Rognum, TO; Saugstad, OD; Stoltenberg, L; Storm, H, 1995)
"The maturation of the process of spontaneous recovery from hypoxic apnea by gasping (autoresuscitation) was characterized in adult, weanling (18-22 d), and infant (5 and 10 d) BALB/c mice."7.68Maturation of cardiorespiratory interactions in spontaneous recovery from hypoxic apnea (autoresuscitation). ( Gershan, WM; Jacobi, MS; Thach, BT, 1990)
" Three groups were examined: 17 were of postconceptual age greater than or equal to 37 weeks, 16 were postconceptual age less than or equal to 35 weeks without apnea and 10 were of postconceptual age less than or equal to 35 weeks with apnea."7.68Cerebrospinal fluid and plasma beta-endorphin-like immunoreactivity in full-term neonates and in preterm neonates with and without apnea of prematurity. ( Arthur-Smith, A; Bors, Z; Herman, BH; Kammerman, LA; MacDonald, MG, 1990)
"The mechanism of failure of autoresuscitation from hypoxic apnea in 17- to 23-day-old (weanling) Swiss Webster related/J mice was investigated by recording electrocardiogram (ECG) and ventilation in adult, weanling, and 11-day-old mice."7.68Mechanism of failure of recovery from hypoxic apnea by gasping in 17- to 23-day-old mice. ( Gershan, WM; Jacobi, MS; Thach, BT, 1991)
"The effect of maturation and motor activity on recovery from hypoxic apnea by gasping (autoresuscitation) was investigated in Swiss Webster mice and a SW-related strain."7.67Effect of maturation on spontaneous recovery from hypoxic apnea by gasping. ( Jacobi, MS; Thach, BT, 1989)
"The sleep state characteristics of infant sleep apnea were studied in 36 twins examined by polygraphy at 40, 44, and 52 weeks after conception."7.65The sleep state characteristics of apnea during infancy. ( Fineberg, N; Gould, JB; James, O; Lee, AF; Sander, L; Teager, H, 1977)
"Caffeine half-life was greatly increased in two infants who had cholestatic hepatitis secondary to prolonged parenteral alimentation and one infant who was breast-fed exclusively."5.27Maturational changes of caffeine concentrations and disposition in infancy during maintenance therapy for apnea of prematurity: influence of gestational age, hepatic disease, and breast-feeding. ( Billon, B; Le Guennec, JC; Paré, C, 1985)
" Older children had a longer duration of apnea than infants, 331 vs 180 s (P < 0."5.14The effect of age on the dose of remifentanil for tracheal intubation in infants and children. ( Ansermino, JM; Brant, R; Hume-Smith, H; Malherbe, S; McCormack, J; Mehta, D; Montgomery, C, 2010)
"The analysis suggests that, if it is assumed that the statistical models used are equally valid over the full range of ages considered and that the average rate of apnea reported across the studies analyzed is accurate and representative of actual rates in all institutions, the probability of apnea in nonanemic infants free of recovery-room apnea is not less than 5%, with 95% statistical confidence until postconceptual age was 48 weeks with gestational age 35 weeks."5.08Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. ( Coté, CJ; Downes, JJ; Kurth, CD; Malviya, SV; Warner, LO; Welborn, LG; Zaslavsky, A, 1995)
"While diving, seals are exposed to apnea-induced hypoxemia and repetitive cycles of ischemia/reperfusion."4.88Coping with physiological oxidative stress: a review of antioxidant strategies in seals. ( Elsner, R; Ortiz, RM; Vázquez-Medina, JP; Zenteno-Savín, T, 2012)
"Methylxanthine therapy reduces the frequency of apnea and the need for mechanical ventilation."4.82Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial. ( Schmidt, B, 2005)
" However, the rapid onset of drug effect may be accompanied by rapid onset of adverse events such as apnea and muscle rigidity."4.80The role of newer opioids in geriatric anesthesia. ( Shafer, SL, 1998)
" One group of neonates at high risk for SIDS includes those who develop apnea secondary to gastroesophageal reflux (GER)."4.78Effects of acid on the larynx of the maturing rabbit and their possible significance to the sudden infant death syndrome. ( Wetmore, RF, 1993)
" Although there is some evidence that longer apnea can be elicited in the neonate than in the adult, the use of anesthesia, which may more strongly depress respiration in the young, complicates the issue."4.76Function of the larynx in the fetus and newborn. ( Harding, R, 1984)
" However, neonatal A1R(-/-) mice appeared to have more frequently periods of apnea during hypoxia and in the post-hypoxic control period."3.83The in vivo respiratory phenotype of the adenosine A1 receptor knockout mouse. ( Buehler, P; Georgieff, M; Heitzmann, D; Schweda, F; Thomas, J; Warth, R, 2016)
" MSNA (microneurography) was measured at baseline and during maximal voluntary end-inspiratory (EI) and end-expiratory (EE) apneas."3.83Effects of aging and coronary artery disease on sympathetic neural recruitment strategies during end-inspiratory and end-expiratory apnea. ( Badrov, MB; Lalande, S; Olver, TD; Shoemaker, JK; Suskin, N, 2016)
" PRKO mice exhibited similar levels of minute ventilation during non-REM and REM sleep, and higher frequencies of sighs and post-sigh apneas during non-REM sleep compared to WT."3.80The nuclear progesterone receptor reduces post-sigh apneas during sleep and increases the ventilatory response to hypercapnia in adult female mice. ( Boukari, R; Joseph, V; Laouafa, S; Lavoie, R; Marcouiller, F, 2014)
" In 10 young (26 ± 1 yr) and 11 older (67 ± 2 yr) subjects, we quantified acute hemodynamic responses to three sympathoexcitatory stimuli: local cooling of the forehead, cold pressor test (CPT), and voluntary apnea."3.79Effect of healthy aging on renal vascular responses to local cooling and apnea. ( Mast, JL; Muller, MD; Patel, HM; Sinoway, LI, 2013)
"We measured the duration of apnea induced by sustained end-inspiratory lung inflation (the Hering Breuer Reflex, HBR) in unanesthetized infant rat pups aged 4 days (P4) to P20 at body temperatures of 32°C and 36°C."3.79Influence of age, body temperature, GABAA receptor inhibition and caffeine on the Hering-Breuer inflation reflex in unanesthetized rat pups. ( Arnal, AV; Bartlett, D; Gore, JL; Leiter, JC; Rudkin, A, 2013)
" These big augmented breaths in infants are often followed by apnea and hypoventilation likely secondary to the increased activity of the peripheral chemoreceptors present in neonates."3.75Morphology of sighs and their role in the control of breathing in preterm infants, term infants and adults. ( Alvaro, RE; Khalil, M; Kwiatkowski, K; Qureshi, M, 2009)
"Both AR and NAR are risk factors for a high apnea-hypopnea index, and both can predispose to sleep apnea."3.75Allergic and nonallergic rhinitis: the threat for obstructive sleep apnea. ( Ekici, M; Kalpaklioğlu, AF; Kavut, AB, 2009)
"Seventy-six normal subjects (40 men) without sleep apnea or periodic limb movements of sleep, aged 18 to 70 years, slept in the sleep laboratory for 1 or more nights."3.74EEG arousal norms by age. ( Arand, DL; Bonnet, MH, 2007)
" Studies in which cough and other airway protective responses have been stimulated by introducing a small bolus of water or saline into the pharynx of sleeping infants have found that the predominant responses are swallowing, apnea and laryngeal closure."3.74Maturation of cough and other reflexes that protect the fetal and neonatal airway. ( Thach, BT, 2007)
"Apnea and respiratory failure often occur in infants with pulmonary disease."3.73Postnatal development of right atrial injection of capsaicin-induced apneic response in rats. ( Wang, R; Xu, F, 2006)
" Swallow apnea increased with age (5 ml of water r = 0."3.73Swallow respiratory patterns and aging: presbyphagia or dysphagia? ( Drinnan, MJ; Ford, GA; Leslie, P; Wilson, JA, 2005)
" Differences in apnea duration and apnea offset occurred with advanced age."3.73Breathing and swallowing dynamics across the adult lifespan. ( Brodsky, MB; Ford, CL; Heffner, J; Martin-Harris, B; Michel, Y; Walters, B, 2005)
" Significant lactate signals were found in seven patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) during sleep periods, and none during periods of arousal."3.72Age-related changes in cerebral lactate metabolism in sleep-disordered breathing. ( Higami, S; Inoue, Y; Kamba, M; Suto, Y, 2003)
" Apneas were frequent at P(0) (occupying 29 +/- 6% of total time) but rare by P(3) (5 +/- 2% of total time)."3.70Development of the ventilatory response to hypoxia in Swiss CD-1 mice. ( Adams, BM; Funk, GD; Kwok, H; Peebles, KC; Robinson, DM, 2000)
"During periods of regular breathing, heart rate is slower and more variable in healthy (no history of respiratory distress syndrome) prematurely born infants with persistent apnea, relative to full-term control infants of comparable post-conceptional ages."3.70Developmental patterns of heart rate and variability in infants with persistent apnea of infancy. ( Harper, RM; Henslee, JA; Schechtman, VL, 1998)
" Plasma concentrations at terminal apnea were higher for ropivacaine than for bupivacaine at all ages, and were higher in infants than in older rats."3.70Sciatic nerve blockade in infant, adolescent, and adult rats: a comparison of ropivacaine with bupivacaine. ( Berde, CB; Hu, D; Kohane, DS; Rifai, N; Sankar, WN; Shubina, M, 1998)
" the apnea-bradycardia-hypotension triad) is mediated through a reflex central cholinergic pathway."3.69Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves. ( Amory, H; Desmecht, DJ; Lekeux, PM; Linden, AS, 1996)
" After a postsurgery recovery of at least 7 days, we studied all animals to detect the presence of apnea and the consequences of it, if any."3.69Age-dependent vulnerability to carotid chemodenervation in piglets. ( Côté, A; Meehan, B; Porras, H, 1996)
" Swallowing-related apnea time (SAT) was measured during "dry" and "wet" swallowing in 84 adults without dysphagia to examine if age-related variation of SAT corresponded to changes in deglutition dynamics due to aging and to determine possible significance."3.69Factors that affect swallowing-related apnea times in humans. ( Komiyama, S; Miyazaki, H; Yamashita, H, 1994)
" The laryngeal chemoreflex-induced apnea was shortened in the piglet group pretreated with water i."3.69Beta-endorphin may be a mediator of apnea induced by the laryngeal chemoreflex in piglets. ( Oyasaeter, S; Reichelt, KL; Rognum, TO; Saugstad, OD; Stoltenberg, L; Storm, H, 1995)
" At 40 weeks post-conception, prematurely-born infants with apnea of prematurity showed higher heart rates and reduced heart rate variability than did full-term neonates."3.69Developmental patterns of heart rate and variability in prematurely-born infants with apnea of prematurity. ( Harper, RM; Henslee, JA; Lee, MY; Schechtman, VL, 1997)
" Similarly, duration and efficiency of gasping, a unique mechanism for enhancing survival after anoxia-induced apnea, are also affected by postnatal age."3.69Characterization and developmental aspects of anoxia-induced gasping in the rat. ( Gozal, D; Gozal, YM; Nuckton, TJ; Torres, JE, 1996)
"We recently showed that the glottis is actively closed throughout post-hyperventilation, hypocapnic central apnea in lambs."3.69Prolonged active glottic closure after barbiturate-induced respiratory arrest in lambs. ( Dalle, D; Diaz, V; Kianicka, I; Leroux, JF; Praud, JP, 1996)
"The mechanism of failure of autoresuscitation from hypoxic apnea in 17- to 23-day-old (weanling) Swiss Webster related/J mice was investigated by recording electrocardiogram (ECG) and ventilation in adult, weanling, and 11-day-old mice."3.68Mechanism of failure of recovery from hypoxic apnea by gasping in 17- to 23-day-old mice. ( Gershan, WM; Jacobi, MS; Thach, BT, 1991)
" Three groups were examined: 17 were of postconceptual age greater than or equal to 37 weeks, 16 were postconceptual age less than or equal to 35 weeks without apnea and 10 were of postconceptual age less than or equal to 35 weeks with apnea."3.68Cerebrospinal fluid and plasma beta-endorphin-like immunoreactivity in full-term neonates and in preterm neonates with and without apnea of prematurity. ( Arthur-Smith, A; Bors, Z; Herman, BH; Kammerman, LA; MacDonald, MG, 1990)
"The maturation of the process of spontaneous recovery from hypoxic apnea by gasping (autoresuscitation) was characterized in adult, weanling (18-22 d), and infant (5 and 10 d) BALB/c mice."3.68Maturation of cardiorespiratory interactions in spontaneous recovery from hypoxic apnea (autoresuscitation). ( Gershan, WM; Jacobi, MS; Thach, BT, 1990)
"The effect of maturation and motor activity on recovery from hypoxic apnea by gasping (autoresuscitation) was investigated in Swiss Webster mice and a SW-related strain."3.67Effect of maturation on spontaneous recovery from hypoxic apnea by gasping. ( Jacobi, MS; Thach, BT, 1989)
" Hypoxia did not significantly affect the LAR or apnea duration in animals with only one intact SLN."3.67Laryngeal chemoreflex: anatomic and physiologic study by use of the superior laryngeal nerve in the piglet. ( Goding, GS; Richardson, MA; Trachy, RE, 1987)
"Five neonates (4 premature) and 16 infants (6 prematurely born), 15-588 days old, received caffeine as citrate salt for apnea."3.67Developmental changes of caffeine elimination in infancy. ( Badoual, J; Carrier, O; d'Athis, P; Moran, C; Olive, G; Pons, G; Rey, E; Richard, MO, 1988)
"Theophylline (T) tissue distribution was studied in 11 premature newborns treated with T for prematurity apnea, who had died from severe pathology."3.66Theophylline distribution in the premature neonate. ( Assael, BM; Bonati, M; Latini, R; Marra, G; Parini, R, 1981)
"5%) caused extended apnea."3.66Laryngeal reflex inhibition of breathing in piglets: influences of anemia and catecholamine depletion. ( Downing, SE; Lee, JC, 1980)
"The sleep state characteristics of infant sleep apnea were studied in 36 twins examined by polygraphy at 40, 44, and 52 weeks after conception."3.65The sleep state characteristics of apnea during infancy. ( Fineberg, N; Gould, JB; James, O; Lee, AF; Sander, L; Teager, H, 1977)
"Midazolam pretreatment was associated with a significant reduction in propofol dose requirement in both younger and older patients."2.70Effect of midazolam pretreatment on induction dose requirements of propofol in combination with fentanyl in younger and older adults. ( Bhaskaran, NC; Claydon, P; Cressey, DM; Reilly, CS, 2001)
"It is characterized by infantile seizures refractory to anticonvulsive treatments, microcephaly, delays in mental and motor development, spasticity, ataxia, dysarthria and other paroxysmal neurologic phenomena, often occurring prior to meals."2.44[Glucose transporter type 1 (GLUT-1) deficiency]. ( Cano, A; Chabrol, B; Ticus, I, 2008)
"End-stage renal disease (ESRD) is characterized by resting sympathetic overactivity."1.35Differential distribution of muscle and skin sympathetic nerve activity in patients with end-stage renal disease. ( Campese, VM; Middlekauff, HR; Nobakht, N; Park, J, 2008)
"9 as an end point for pre-oxygenation, we have compared the time taken to achieve this end point and the safe duration of apnoea after induction of anaesthesia following pre-oxygenation in elderly patients and young adults."1.30End-tidal oxygraphy and safe duration of apnoea in young adults and elderly patients. ( Bhandari, SC; Bhatia, PK; Kumar, Y; Tulsiani, KL, 1997)
"Twenty-one subjects had bilateral choanal atresia/stenosis; 12 had unilateral choanal atresia/stenosis, and eight who were referred with suspected choanal atresia had a simple inflammatory nasal obstruction."1.27Clinical manifestations of choanal atresia in infancy. ( Colarossi, G; Cozzi, F; Madonna, L; Rosati, D; Steiner, M, 1988)
"Caffeine half-life was greatly increased in two infants who had cholestatic hepatitis secondary to prolonged parenteral alimentation and one infant who was breast-fed exclusively."1.27Maturational changes of caffeine concentrations and disposition in infancy during maintenance therapy for apnea of prematurity: influence of gestational age, hepatic disease, and breast-feeding. ( Billon, B; Le Guennec, JC; Paré, C, 1985)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199016 (25.81)18.7374
1990's22 (35.48)18.2507
2000's16 (25.81)29.6817
2010's8 (12.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patel, HM1
Mast, JL1
Sinoway, LI1
Muller, MD1
Marcouiller, F1
Boukari, R1
Laouafa, S1
Lavoie, R1
Joseph, V1
Heitzmann, D1
Buehler, P1
Schweda, F1
Georgieff, M1
Warth, R1
Thomas, J1
Badrov, MB1
Lalande, S1
Olver, TD1
Suskin, N1
Shoemaker, JK1
Sohn, JA1
Kim, HS1
Oh, J1
Cho, JY1
Yu, KS1
Lee, J1
Shin, SH1
Lee, JA1
Choi, CW1
Kim, EK1
Kim, BI1
Park, EA1
Cano, A1
Ticus, I1
Chabrol, B1
Park, J1
Campese, VM1
Nobakht, N1
Middlekauff, HR1
Qureshi, M1
Khalil, M1
Kwiatkowski, K1
Alvaro, RE1
Kalpaklioğlu, AF1
Kavut, AB1
Ekici, M1
Hume-Smith, H1
McCormack, J1
Montgomery, C1
Brant, R1
Malherbe, S1
Mehta, D1
Ansermino, JM1
Vázquez-Medina, JP1
Zenteno-Savín, T1
Elsner, R1
Ortiz, RM1
Arnal, AV1
Gore, JL1
Rudkin, A1
Bartlett, D1
Leiter, JC1
Martin-Harris, B2
Brodsky, MB2
Price, CC1
Michel, Y2
Walters, B2
Kamba, M1
Inoue, Y1
Higami, S1
Suto, Y1
Zabka, AG2
Mitchell, GS2
Olson, EB1
Behan, M2
MITOLO, M1
MITOLO, V1
Leslie, P1
Drinnan, MJ1
Ford, GA1
Wilson, JA1
Ford, CL1
Heffner, J1
Schmidt, B1
Wang, R1
Xu, F1
Thach, BT4
Bonnet, MH1
Arand, DL1
Harding, R1
Carse, EA1
Wilkinson, AR1
Whyte, PL1
Henderson-Smart, DJ1
Johnson, P1
Bonati, M1
Latini, R1
Marra, G1
Assael, BM1
Parini, R1
Lee, JC1
Downing, SE1
Storm, H1
Stoltenberg, L1
Oyasaeter, S1
Saugstad, OD1
Rognum, TO1
Reichelt, KL1
Fisher, DM1
Coté, CJ1
Zaslavsky, A1
Downes, JJ1
Kurth, CD1
Welborn, LG1
Warner, LO1
Malviya, SV1
Patel, R1
Lenczyk, M1
Hannallah, RS1
McGill, WA1
Wetmore, RF1
Wolsink, JG1
Berkenbosch, A1
DeGoede, J1
Olievier, CN1
Wallois, F1
Khater-Boidin, J1
Dusaussoy, F1
Duron, B1
Linden, AS1
Desmecht, DJ1
Amory, H1
Lekeux, PM1
Côté, A1
Porras, H1
Meehan, B1
Praud, JP1
Kianicka, I1
Diaz, V1
Leroux, JF1
Dalle, D1
Gozal, D1
Torres, JE1
Gozal, YM1
Nuckton, TJ1
Bhatia, PK1
Bhandari, SC1
Tulsiani, KL1
Kumar, Y1
Henslee, JA2
Schechtman, VL2
Lee, MY1
Harper, RM2
Shafer, SL1
Kohane, DS1
Sankar, WN1
Shubina, M1
Hu, D1
Rifai, N1
Berde, CB1
Tateishi, T1
Asoh, M1
Yamaguchi, A1
Yoda, T1
Okano, YJ1
Koitabashi, Y1
Kobayashi, S1
Robinson, DM1
Kwok, H1
Adams, BM1
Peebles, KC1
Funk, GD1
Cressey, DM1
Claydon, P1
Bhaskaran, NC1
Reilly, CS1
Miyazaki, H1
Yamashita, H1
Komiyama, S1
Gould, JB1
Lee, AF1
James, O1
Sander, L1
Teager, H1
Fineberg, N1
Buchanan, N1
Shaker, R1
Li, Q1
Ren, J1
Townsend, WF1
Dodds, WJ1
Martin, BJ1
Kern, MK1
Rynders, A1
Jacobi, MS3
Gershan, WM2
MacDonald, MG1
Herman, BH1
Kammerman, LA1
Bors, Z1
Arthur-Smith, A1
Lainé-Cessac, P1
Turcant, A1
Allain, P1
Goding, GS1
Richardson, MA1
Trachy, RE1
Pons, G1
Carrier, O1
Richard, MO1
Rey, E1
d'Athis, P1
Moran, C1
Badoual, J1
Olive, G1
Cozzi, F1
Steiner, M1
Rosati, D1
Madonna, L1
Colarossi, G1
Southall, DP1
Alexander, JR1
Stebbens, VA1
Taylor, VG1
Janczynski, RE1
Le Guennec, JC1
Billon, B1
Paré, C1
Nixon, P1
Bethell, HJ1
Farber, JP1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths in Neonate: Effect on Carbon Dioxide Level[NCT05682937]50 participants (Anticipated)Interventional2023-01-12Enrolling by invitation
Study to Evaluate the Optimal Dose of Remifentanil Required to Ensure Apnoea During Magnetic Resonance Imaging of the Heart Under General Anaesthesia[NCT02481791]Phase 335 participants (Anticipated)Interventional2015-07-31Recruiting
Experienced Breacher Study: Evaluation of the Effects From Chronic Exposure to Low-Level Blast[NCT01524822]66 participants (Actual)Observational2012-07-30Completed
Apneic Oxygenation to Prevent Oxygen Desaturation During Intubation in the NICU[NCT05451953]110 participants (Anticipated)Interventional2022-07-21Recruiting
A Randomized, Placebo-Controlled Assessment of Lansoprazole 30 mg Bid in the Treatment of Gastroesophageal Reflux Associated With Laryngitis[NCT00369265]Phase 418 participants (Actual)Interventional2006-08-31Terminated (stopped due to Pharmaceutical company purchased by another company and funding was terminated.)
End-tidal Oxygen Can Reliably Predict the Arterial Partial Pressure of Oxygen Among Emergency Department Patients Undergoing Rapid Sequence Intubation[NCT03842306]75 participants (Actual)Observational2017-10-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for apnea and Aging

ArticleYear
[Glucose transporter type 1 (GLUT-1) deficiency].
    Revue neurologique, 2008, Volume: 164, Issue:11

    Topics: Aging; Apnea; Blood-Brain Barrier; Brain Diseases; Developmental Disabilities; Glucose Transporter T

2008
Coping with physiological oxidative stress: a review of antioxidant strategies in seals.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2012, Volume: 182, Issue:6

    Topics: Adaptation, Physiological; Aging; Animals; Antioxidants; Apnea; Diving; Fasting; Hypoxia; Oxidative

2012
Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial.
    Biology of the neonate, 2005, Volume: 88, Issue:3

    Topics: Aging; Apnea; Blindness; Cerebral Palsy; Cognition Disorders; Deafness; Follow-Up Studies; Humans; I

2005
Function of the larynx in the fetus and newborn.
    Annual review of physiology, 1984, Volume: 46

    Topics: Aging; Airway Resistance; Animals; Animals, Newborn; Apnea; Body Fluids; Cardiovascular Physiologica

1984
Effects of acid on the larynx of the maturing rabbit and their possible significance to the sudden infant death syndrome.
    The Laryngoscope, 1993, Volume: 103, Issue:11 Pt 1

    Topics: Aging; Airway Obstruction; Animals; Apnea; Female; Gastroesophageal Reflux; Humans; Hydrochloric Aci

1993
The role of newer opioids in geriatric anesthesia.
    Acta anaesthesiologica Belgica, 1998, Volume: 49, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics,

1998
Clinical pharmacology of theophylline.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Jul-14, Volume: 56, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aging; Apnea; Arterioles; Biological Availability; Bronchia

1979

Trials

3 trials available for apnea and Aging

ArticleYear
The effect of age on the dose of remifentanil for tracheal intubation in infants and children.
    Paediatric anaesthesia, 2010, Volume: 20, Issue:1

    Topics: Adjuvants, Anesthesia; Aging; Anesthetics, Intravenous; Apnea; Blood Gas Analysis; Child, Preschool;

2010
Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis.
    Anesthesiology, 1995, Volume: 82, Issue:4

    Topics: Aging; Analysis of Variance; Anemia; Anesthesia; Apnea; Birth Weight; Hernia, Inguinal; Humans; Infa

1995
Effect of midazolam pretreatment on induction dose requirements of propofol in combination with fentanyl in younger and older adults.
    Anaesthesia, 2001, Volume: 56, Issue:2

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Aging; Analysis of Variance; Anesthetics, Intravenou

2001

Other Studies

52 other studies available for apnea and Aging

ArticleYear
Effect of healthy aging on renal vascular responses to local cooling and apnea.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Jul-01, Volume: 115, Issue:1

    Topics: Adult; Aged; Aging; Apnea; Arterial Pressure; Cold Temperature; Cross-Over Studies; Female; Forehead

2013
The nuclear progesterone receptor reduces post-sigh apneas during sleep and increases the ventilatory response to hypercapnia in adult female mice.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Aging; Animals; Apnea; Cell Nucleus; Electroencephalography; Electromyography; Female; Hypercapnia;

2014
The in vivo respiratory phenotype of the adenosine A1 receptor knockout mouse.
    Respiratory physiology & neurobiology, 2016, Feb-01, Volume: 222

    Topics: Aging; Animals; Animals, Newborn; Apnea; Blood Gas Analysis; Disease Models, Animal; Female; Hyperca

2016
Effects of aging and coronary artery disease on sympathetic neural recruitment strategies during end-inspiratory and end-expiratory apnea.
    American journal of physiology. Heart and circulatory physiology, 2016, 10-01, Volume: 311, Issue:4

    Topics: Action Potentials; Adult; Age Factors; Aged; Aging; Apnea; Arterial Pressure; Blood Pressure; Breath

2016
Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:6

    Topics: Aging; Apnea; Bronchodilator Agents; Cytochrome P-450 CYP1A2; Female; Genotype; Gestational Age; Hum

2017
Differential distribution of muscle and skin sympathetic nerve activity in patients with end-stage renal disease.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:6

    Topics: Adult; Aging; Apnea; Baroreflex; Blood Pressure; Body Mass Index; Electrophysiology; Female; Heart R

2008
Morphology of sighs and their role in the control of breathing in preterm infants, term infants and adults.
    Neonatology, 2009, Volume: 96, Issue:1

    Topics: Adult; Aging; Apnea; Humans; Hypoventilation; Infant, Newborn; Infant, Premature; Movement; Respirat

2009
Allergic and nonallergic rhinitis: the threat for obstructive sleep apnea.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 103, Issue:1

    Topics: Adult; Aging; Apnea; Asthma; Body Mass Index; Disorders of Excessive Somnolence; Female; Humans; Mal

2009
Influence of age, body temperature, GABAA receptor inhibition and caffeine on the Hering-Breuer inflation reflex in unanesthetized rat pups.
    Respiratory physiology & neurobiology, 2013, Mar-01, Volume: 186, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Apnea; Body Temperature; Caffeine; Central Nervous System Stimulan

2013
Temporal coordination of pharyngeal and laryngeal dynamics with breathing during swallowing: single liquid swallows.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:5

    Topics: Adult; Aging; Apnea; Barium Sulfate; Black People; Deglutition; Female; Humans; Larynx; Male; Pharyn

2003
Age-related changes in cerebral lactate metabolism in sleep-disordered breathing.
    Neurobiology of aging, 2003, Volume: 24, Issue:5

    Topics: Adult; Aged; Aging; Apnea; Body Mass Index; Cerebral Cortex; Female; Humans; Lactic Acid; Magnetic R

2003
Selected contribution: chronic intermittent hypoxia enhances respiratory long-term facilitation in geriatric female rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 95, Issue:6

    Topics: Aging; Algorithms; Animals; Apnea; Blood Pressure; Caloric Restriction; Carbon Dioxide; Estrous Cycl

2003
[Training in the test of maximum voluntary apnea in aged subjects; biologico-statistical study].
    Bollettino della Societa italiana di biologia sperimentale, 1956, Volume: 32, Issue:9

    Topics: Aging; Apnea; Humans; Pulmonary Ventilation; Respiratory Function Tests

1956
Ageing and gonadectomy have similar effects on hypoglossal long-term facilitation in male Fischer rats.
    The Journal of physiology, 2005, Mar-01, Volume: 563, Issue:Pt 2

    Topics: Aging; Animals; Apnea; Carbon Dioxide; Hypoglossal Nerve; Hypoxia; Long-Term Potentiation; Male; Orc

2005
Swallow respiratory patterns and aging: presbyphagia or dysphagia?
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2005, Volume: 60, Issue:3

    Topics: Adult; Age Factors; Aged; Aging; Apnea; Cohort Studies; Deglutition; Deglutition Disorders; Diagnosi

2005
Breathing and swallowing dynamics across the adult lifespan.
    Archives of otolaryngology--head & neck surgery, 2005, Volume: 131, Issue:9

    Topics: Adult; Age Factors; Aged; Aging; Apnea; Deglutition; Female; Fluoroscopy; Humans; Larynx; Male; Midd

2005
Postnatal development of right atrial injection of capsaicin-induced apneic response in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Apnea; Capsaicin; Exhalation; Heart Atria; Injections; Lung Volume

2006
Maturation of cough and other reflexes that protect the fetal and neonatal airway.
    Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:4

    Topics: Aging; Animals; Apnea; Chemoreceptor Cells; Cough; Deglutition; Fetal Development; Fetus; Humans; In

2007
EEG arousal norms by age.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2007, Apr-15, Volume: 3, Issue:3

    Topics: Adolescent; Age Factors; Aged; Aging; Apnea; Arousal; Electroencephalography; Female; Humans; Male;

2007
Oxygen and carbon dioxide tensions, breathing and heart rate in normal infants during the first six months of life.
    Journal of developmental physiology, 1981, Volume: 3, Issue:2

    Topics: Aging; Apnea; Carbon Dioxide; Electrocardiography; Electroencephalography; Female; Heart Rate; Human

1981
Theophylline distribution in the premature neonate.
    Developmental pharmacology and therapeutics, 1981, Volume: 3, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Apnea; Blood-Brain Barrier; Female; Gestational Age; Guinea Pigs;

1981
Laryngeal reflex inhibition of breathing in piglets: influences of anemia and catecholamine depletion.
    The American journal of physiology, 1980, Volume: 239, Issue:1

    Topics: Aging; Anemia, Hypochromic; Animals; Apnea; Electric Stimulation; Female; Laryngeal Nerves; Male; Po

1980
Beta-endorphin may be a mediator of apnea induced by the laryngeal chemoreflex in piglets.
    Pediatric research, 1995, Volume: 38, Issue:2

    Topics: Aging; Animals; Apnea; beta-Endorphin; Blood Glucose; Body Weight; Cisterna Magna; Female; Hematocri

1995
When is the ex-premature infant no longer at risk for apnea?
    Anesthesiology, 1995, Volume: 82, Issue:4

    Topics: Aging; Anesthesia, General; Apnea; Humans; Infant, Newborn; Infant, Premature; Risk Factors

1995
Age and the onset of desaturation in apnoeic children.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:9

    Topics: Adolescent; Aging; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Apnea; Body

1994
Maturation of the ventilatory response to CO2 in the newborn piglet.
    Pediatric research, 1993, Volume: 34, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Apnea; Blood Pressure; Carbon Dioxide; Hydrogen-Ion Concentration;

1993
Oral stimulations induce apnoea in newborn kittens.
    Neuroreport, 1993, Volume: 4, Issue:7

    Topics: Aging; Anesthesia; Animals; Animals, Newborn; Apnea; Cats; Decerebrate State; Deglutition; Electric

1993
Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves.
    American journal of veterinary research, 1996, Volume: 57, Issue:6

    Topics: Aging; Animals; Apnea; Atropine; Bradycardia; Cattle; Cattle Diseases; Cholinergic Agents; Ganglioni

1996
Age-dependent vulnerability to carotid chemodenervation in piglets.
    Journal of applied physiology (Bethesda, Md. : 1985), 1996, Volume: 80, Issue:1

    Topics: Aging; Anesthesia; Animals; Animals, Newborn; Apnea; Blood Gas Analysis; Body Temperature; Carotid B

1996
Prolonged active glottic closure after barbiturate-induced respiratory arrest in lambs.
    Respiration physiology, 1996, Volume: 104, Issue:2-3

    Topics: Abdominal Muscles; Aging; Animals; Animals, Newborn; Apnea; Electrodes, Implanted; Electromyography;

1996
Characterization and developmental aspects of anoxia-induced gasping in the rat.
    Biology of the neonate, 1996, Volume: 70, Issue:5

    Topics: Aging; Animals; Apnea; Electrocardiography; Hypoxia; Rats; Rats, Sprague-Dawley; Respiration

1996
End-tidal oxygraphy and safe duration of apnoea in young adults and elderly patients.
    Anaesthesia, 1997, Volume: 52, Issue:2

    Topics: Adult; Aged; Aging; Apnea; Carbon Dioxide; Female; Hemodynamics; Humans; Male; Middle Aged; Monitori

1997
Developmental patterns of heart rate and variability in prematurely-born infants with apnea of prematurity.
    Early human development, 1997, Jan-03, Volume: 47, Issue:1

    Topics: Aging; Apnea; Electrocardiography; Female; Gestational Age; Heart Rate; Humans; Infant, Newborn; Inf

1997
Developmental patterns of heart rate and variability in infants with persistent apnea of infancy.
    Early human development, 1998, Feb-27, Volume: 50, Issue:3

    Topics: Aging; Apnea; Electrocardiography; Gestational Age; Heart Rate; Humans; Infant, Newborn; Infant, Pre

1998
Sciatic nerve blockade in infant, adolescent, and adult rats: a comparison of ropivacaine with bupivacaine.
    Anesthesiology, 1998, Volume: 89, Issue:5

    Topics: Aging; Amides; Anesthetics, Local; Animals; Apnea; Behavior, Animal; Bupivacaine; Dose-Response Rela

1998
Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients.
    Pediatric research, 1999, Volume: 45, Issue:1

    Topics: Aging; Apnea; Asthma; Child, Preschool; Cytochrome P-450 CYP1A2; Humans; Infant; Infant, Newborn; Th

1999
Development of the ventilatory response to hypoxia in Swiss CD-1 mice.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 88, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Apnea; Hypoxia; Mice; Pulmonary Ventilation; Respiration

2000
Factors that affect swallowing-related apnea times in humans.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1994, Volume: 251 Suppl 1

    Topics: Adult; Age Factors; Aged; Aging; Apnea; Deglutition; Female; Humans; Male; Middle Aged; Time Factors

1994
The sleep state characteristics of apnea during infancy.
    Pediatrics, 1977, Volume: 59, Issue:2

    Topics: Aging; Apnea; Diseases in Twins; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant, P

1977
Coordination of deglutition and phases of respiration: effect of aging, tachypnea, bolus volume, and chronic obstructive pulmonary disease.
    The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Apnea; Deglutition; Humans; Lung Diseases, Obstructive; Middl

1992
Mechanism of failure of recovery from hypoxic apnea by gasping in 17- to 23-day-old mice.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:3

    Topics: Aging; Airway Obstruction; Animals; Apnea; Electrocardiography; Heart Rate; Hypoxia; Mice; Mice, Inb

1991
Cerebrospinal fluid and plasma beta-endorphin-like immunoreactivity in full-term neonates and in preterm neonates with and without apnea of prematurity.
    Developmental pharmacology and therapeutics, 1990, Volume: 15, Issue:1

    Topics: Aging; Apnea; beta-Endorphin; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; M

1990
Maturation of cardiorespiratory interactions in spontaneous recovery from hypoxic apnea (autoresuscitation).
    Pediatric research, 1990, Volume: 28, Issue:2

    Topics: Aging; Animals; Apnea; Cardiovascular System; Heart Rate; Hypoxia; Mice; Mice, Inbred BALB C; Oxygen

1990
Effect of maturation on spontaneous recovery from hypoxic apnea by gasping.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:5

    Topics: Aging; Animals; Apnea; Electromyography; Hypoxia; Mice; Mice, Inbred Strains; Motor Activity; Muscle

1989
Automated determination of cholinesterase activity in plasma and erythrocytes by flow-injection analysis, and application to identify subjects sensitive to succinylcholine.
    Clinical chemistry, 1989, Volume: 35, Issue:1

    Topics: Adult; Aging; Anesthesia; Apnea; Autoanalysis; Cholinesterases; Erythrocytes; Female; Humans; Male;

1989
Laryngeal chemoreflex: anatomic and physiologic study by use of the superior laryngeal nerve in the piglet.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1987, Volume: 97, Issue:1

    Topics: Aging; Animals; Apnea; Blood Pressure; Chemoreceptor Cells; Horseradish Peroxidase; Laryngeal Mucosa

1987
Developmental changes of caffeine elimination in infancy.
    Developmental pharmacology and therapeutics, 1988, Volume: 11, Issue:5

    Topics: Aging; Apnea; Caffeine; Drug Administration Schedule; Gestational Age; Half-Life; Humans; Infant; In

1988
Clinical manifestations of choanal atresia in infancy.
    Journal of pediatric surgery, 1988, Volume: 23, Issue:3

    Topics: Aging; Airway Obstruction; Apnea; Autonomic Nervous System Diseases; Child, Preschool; Choanal Atres

1988
Cardiorespiratory patterns in siblings of babies with sudden infant death syndrome.
    Archives of disease in childhood, 1987, Volume: 62, Issue:7

    Topics: Aging; Apnea; Electrocardiography; Family; Follow-Up Studies; Heart Rate; Humans; Infant, Newborn; P

1987
Maturational changes of caffeine concentrations and disposition in infancy during maintenance therapy for apnea of prematurity: influence of gestational age, hepatic disease, and breast-feeding.
    Pediatrics, 1985, Volume: 76, Issue:5

    Topics: Aging; Apnea; Breast Feeding; Caffeine; Cholestasis; Citrates; Drug Combinations; Gestational Age; H

1985
Letter: Presentation of myocardial infarction.
    British medical journal, 1974, Feb-23, Volume: 1, Issue:5903

    Topics: Aging; Angina Pectoris; Apnea; Blood Pressure; Electrocardiography; Fatigue; Humans; Myocardial Infa

1974
Development of pulmonary reflexes and pattern of breathing in Virginia opossum.
    Respiration physiology, 1972, Volume: 14, Issue:3

    Topics: Aging; Animals; Apnea; Asphyxia; Diaphragm; Electromyography; Humans; Hypercapnia; Hypoxia; Intercos

1972