apigetrin has been researched along with Hemolysis* in 2 studies
2 other study(ies) available for apigetrin and Hemolysis
| Article | Year |
|---|---|
Antioxidative glycosides from the leaves of Ligustrum robustum.
Phytochemical investigation of the ethanol extract of the leaves of Ligustrum robustum, monitored by a bioassay involving the hemolysis of red blood cells induced by 2,2'-azo-bis(2-amidinopropane) dihydrochloride, led to the isolation of three new glycosides, ligurobustosides M (1), N (2), and O (3), along with 10 known ones, osmanthuside B (4), osmanthuside B6 (5), acteoside (6), ligupurpuroside A (7), ligupurpuroside B (8), ligurobustoside C (9), ligurobustoside E (10), ligurobustoside I (11), cosmosiin (12), and rhoifolin (13). The structures of the new compounds were elucidated by spectroscopic methods. Seven of the glycosides showed stronger antioxidant effects than the standard, trolox. Topics: Animals; Antioxidants; Chromans; Drugs, Chinese Herbal; Erythrocytes; Glycosides; Hemolysis; Ligustrum; Molecular Structure; Plant Leaves; Plants, Medicinal; Rats | 2003 |
In vitro anticomplementary activity of constituents from Morinda morindoides.
In a screening program for complement classical pathway modulation, an 80% MeOH extract of the leaves of Morinda morindoides showed potent dose-dependent anticomplementary activity. Bioassay-guided chromatographic separation of the active constituents led to the isolation of ten flavonoids of which two were aglycones. The compounds were tested in vitro for their putative complement-inhibiting properties on the classical (CP) and the alternative (AP) pathways of the complement system. The results indicated that quercetin [1], quercetin 3-O-rhamnoside (quercitrin) [5], and quercetin 3-O-rutinoside (rutin) [7] showed similar anticomplementary activities (inhibition) on the CP of complement. A mixture of two kaempferol triglycosides isolated and denoted as M(015), also had a good inhibitory effect. The effects of these compounds were dose-dependent for this pathway. On the AP of complement, quercetin [1] and M(015) had, respectively, more pronounced inhibitory and activatory effects than the other tested flavonoids, but their effects were not dose-dependent for this pathway. The other isolated flavonoids showed weak effects or were inactive for both pathways. Topics: Animals; Complement Inactivator Proteins; Complement Pathway, Alternative; Complement Pathway, Classical; Flavonoids; Guinea Pigs; Hemolysis; Humans; In Vitro Techniques; Plant Extracts; Plant Leaves; Plants, Medicinal; Rabbits; Sheep | 1995 |