apigenin and Lichen-Planus--Oral

apigenin has been researched along with Lichen-Planus--Oral* in 1 studies

Trials

1 trial(s) available for apigenin and Lichen-Planus--Oral

Article	Year
Efficacy of topical chamomile management vs. placebo in patients with oral lichen planus: a randomized double-blind study. Journal of the European Academy of Dermatology and Venereology : JEADV, 2016, Volume: 30, Issue:10 The purpose of this study was to compare the clinical therapeutic efficacy of topical applications of chamomile vs. a placebo for treating oral lichen planus (OLP).. This double-blind study, randomly divided 60 patients with OLP into two groups, 30 treated with 2% Chamaemelum nobile gel (0.5 mL/3 times a day) and 30 treated with a placebo (Trial Registration NCT02421770). A visual analogue scale was used to rate pain, itching and burning sensation, and Thongprasom Index, the Oral Health Impact Profile 14 (OHIP-14) and the Hospital Anxiety-Depression Scale. Patients were evaluated at baseline and after 4 weeks of treatment.. Patients treated with chamomile showed significant improvements after 4 weeks for pain (P < 0.001), burning sensation (P < 0.001), itching (P = 0.011), OHIP-14 (P < 0.001) and Thongprasom index (P = 0.001); 92% of patients treated with chamomile showed a partial or total response, while only five subjects (17%) in the placebo group showed any improvement.. The topical application of 2% chamomile gel is an effective treatment for OLP. Topics: Administration, Topical; Aged; Chamomile; Double-Blind Method; Female; Humans; Lichen Planus, Oral; Male; Middle Aged; Placebos	2016

Article

Year

Efficacy of topical chamomile management vs. placebo in patients with oral lichen planus: a randomized double-blind study.

Journal of the European Academy of Dermatology and Venereology : JEADV, 2016, Volume: 30, Issue:10

The purpose of this study was to compare the clinical therapeutic efficacy of topical applications of chamomile vs. a placebo for treating oral lichen planus (OLP).. This double-blind study, randomly divided 60 patients with OLP into two groups, 30 treated with 2% Chamaemelum nobile gel (0.5 mL/3 times a day) and 30 treated with a placebo (Trial Registration NCT02421770). A visual analogue scale was used to rate pain, itching and burning sensation, and Thongprasom Index, the Oral Health Impact Profile 14 (OHIP-14) and the Hospital Anxiety-Depression Scale. Patients were evaluated at baseline and after 4 weeks of treatment.. Patients treated with chamomile showed significant improvements after 4 weeks for pain (P < 0.001), burning sensation (P < 0.001), itching (P = 0.011), OHIP-14 (P < 0.001) and Thongprasom index (P = 0.001); 92% of patients treated with chamomile showed a partial or total response, while only five subjects (17%) in the placebo group showed any improvement.. The topical application of 2% chamomile gel is an effective treatment for OLP.

Topics: Administration, Topical; Aged; Chamomile; Double-Blind Method; Female; Humans; Lichen Planus, Oral; Male; Middle Aged; Placebos

2016