apigenin and Dermatitis--Allergic-Contact

Topics: Chamomile; Cosmetics; Dermatitis, Allergic Contact; Humans; Plant Extracts; Urticaria

Compositae-sensitive patients are routinely warned against topical use of Compositae-containing cosmetics and herbal remedies. However, the risk of elicitation of dermatitis in presensitized persons is unknown.. The main aim of this study was to assess the significance of direct plant allergen contact via Compositae-derived cosmetics and herbal remedies in Compositae-allergic patients with special reference to arnica (Arnica montana) and German chamomile (Chamomilla recutita).. 8 of 12 chamomile-sensitive patients tested positive to chamomile-containing preparations, including tea, creams, ointments, and oil. 5 of 6 arnica-sensitive persons tested positive to arnica-based products.. When the group was patch tested with cosmetic and/or herbal product ingredients, plant allergens elicited positive reactions most frequently, but fragrances, emulsifiers, and preservatives tested positive as well. Plant allergens were mainly derived from Compositae, but avocado oil, and Hamamelis virginiana tincture were unexpectedly detected as sensitizers too. Chemical analyses indicated that the Compositae allergens were both sesquiterpene lactones and other naturally occurring compounds.. In conclusion, Compositae-allergic persons should be warned against topical use of Compositae-containing products, not only because of the plant allergens, but also because of allergenic cream constituents that may cause reactions in the group of patients who have multiple contact allergies beside the Compositae allergy.

Topics: Administration, Cutaneous; Arnica; Asteraceae; Chamomile; Cosmetics; Dermatitis, Allergic Contact; Female; Gas Chromatography-Mass Spectrometry; Hamamelis; Humans; Male; Middle Aged; Patch Tests; Persea; Phytotherapy; Plant Extracts; Plant Oils; Plant Preparations; Prospective Studies

Patients with contact allergy to sesquiterpene lactones (SLs) are usually hypersensitive to Asteraceae plant products such as herbal teas. The objective of this study was to show sensitizers in chamomile tea by patch testing with thin-layer chromatograms. Tea made from German chamomile was separated by thin-layer chromatography. Strips of the thin-layer chromatograms were used for patch testing SL-positive patients. 15 (43%) of 35 patients tested positively to 1 or more spots on the thin-layer chromatogram, with many individual reaction patterns. Patch testing with thin-layer chromatograms of German chamomile tea showed the presence of several allergens.

Topics: Adult; Aged; Allergens; Case-Control Studies; Chamomile; Chromatography, Thin Layer; Dermatitis, Allergic Contact; Female; Hand Dermatoses; Humans; Lactones; Male; Middle Aged; Patch Tests; Sesquiterpenes; Tea

Topics: Adult; Allergens; Chamomile; Dermatitis, Allergic Contact; Diagnosis, Differential; Facial Dermatoses; Female; Humans; Patch Tests; Recurrence; Tea

Topics: Allergens; Asthma; Calcium Compounds; Chamomile; Dermatitis, Allergic Contact; Dermatitis, Occupational; Diagnosis, Differential; Female; Flowers; Hand Dermatoses; Humans; Intradermal Tests; Middle Aged; Oxides; Patch Tests; Rhinitis

Topics: Administration, Topical; Adult; Chamomile; Dermatitis, Allergic Contact; Dermatitis, Atopic; Eczema; Facial Dermatoses; Female; Homeopathy; Humans; Patch Tests; Phytotherapy; Plants, Medicinal; Prognosis

Topics: Adult; Angioedema; Chamomile; Dermatitis, Allergic Contact; Eyelid Diseases; Female; Humans; Plants, Medicinal; Skin Tests; Tea

Topics: Aged; Chamomile; Cosmetics; Dermatitis, Allergic Contact; Drug Combinations; Female; Flavonoids; Humans; Irritants; Oils, Volatile; Patch Tests; Plant Extracts; Plants, Medicinal; Sesquiterpenes

Topics: Adult; Chamomile; Dermatitis, Allergic Contact; Facial Dermatoses; Female; Flavonoids; Humans; Oils, Volatile; Patch Tests; Plant Extracts; Plants, Medicinal; Tea

Topics: Aged; Aged, 80 and over; Animals; Chamomile; Dermatitis, Allergic Contact; Flavonoids; Humans; Male; Oils, Volatile; Plant Extracts; Plants, Medicinal