aphidicolin and Herpes-Zoster

aphidicolin has been researched along with Herpes-Zoster* in 1 studies

Other Studies

1 other study(ies) available for aphidicolin and Herpes-Zoster

Article	Year
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases. Bioorganic & medicinal chemistry letters, 2007, Jun-15, Volume: 17, Issue:12 A novel series of 2-aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potent antivirals against human herpesviruses. These compounds demonstrate broad-spectrum inhibition of the herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases. Topics: Antiviral Agents; Binding, Competitive; Cytomegalovirus; DNA-Directed DNA Polymerase; Enzyme Inhibitors; Ethylamines; Exodeoxyribonucleases; Herpes Zoster; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 4, Human; Humans; Models, Chemical; Nucleic Acid Synthesis Inhibitors; Pyridines; Structure-Activity Relationship; Viral Proteins	2007

Article

Year

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.

Bioorganic & medicinal chemistry letters, 2007, Jun-15, Volume: 17, Issue:12

A novel series of 2-aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potent antivirals against human herpesviruses. These compounds demonstrate broad-spectrum inhibition of the herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases.

Topics: Antiviral Agents; Binding, Competitive; Cytomegalovirus; DNA-Directed DNA Polymerase; Enzyme Inhibitors; Ethylamines; Exodeoxyribonucleases; Herpes Zoster; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 4, Human; Humans; Models, Chemical; Nucleic Acid Synthesis Inhibitors; Pyridines; Structure-Activity Relationship; Viral Proteins

2007