apatinib and Mycoses
apatinib has been researched along with Mycoses* in 1 studies
Other Studies
1 other study(ies) available for apatinib and Mycoses
| Article | Year |
|---|---|
Effects of ketoconazole, voriconazole, and itraconazole on the pharmacokinetics of apatinib in rats.
We investigated the effect of azole antifungal drugs (ketoconazole, voriconazole, and itraconazole) on the pharmacokinetics of apatinib in rats. The rats in ketoconazole, voriconazole, and itraconazole groups received single-dose apatinib 30 mg/kg after the oral administration of ketoconazole, voriconazole, and itraconazole, respectively. Co-administration of ketoconazole or voriconazole significantly increased the apatinib C Topics: Animals; Antifungal Agents; Antineoplastic Agents; Drug Evaluation, Preclinical; Drug Interactions; Drug Monitoring; Itraconazole; Ketoconazole; Male; Mycoses; Pyridines; Rats; Rats, Sprague-Dawley; Stomach Neoplasms; Voriconazole | 2019 |