ap20187 and Obesity

ap20187 has been researched along with Obesity* in 1 studies

Other Studies

1 other study(ies) available for ap20187 and Obesity

Article	Year
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis. Cell metabolism, 2019, 05-07, Volume: 29, Issue:5 Cellular senescence entails a stable cell-cycle arrest and a pro-inflammatory secretory phenotype, which contributes to aging and age-related diseases. Obesity is associated with increased senescent cell burden and neuropsychiatric disorders, including anxiety and depression. To investigate the role of senescence in obesity-related neuropsychiatric dysfunction, we used the INK-ATTAC mouse model, from which p16 Topics: Animals; Anxiety; Astrocytes; Behavior, Animal; Brain; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Dasatinib; Diet, High-Fat; Disease Models, Animal; Female; Fibroblasts; Lipid Droplets; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Obesity; Quercetin; Tacrolimus	2019

Article

Year

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.

Cell metabolism, 2019, 05-07, Volume: 29, Issue:5

Cellular senescence entails a stable cell-cycle arrest and a pro-inflammatory secretory phenotype, which contributes to aging and age-related diseases. Obesity is associated with increased senescent cell burden and neuropsychiatric disorders, including anxiety and depression. To investigate the role of senescence in obesity-related neuropsychiatric dysfunction, we used the INK-ATTAC mouse model, from which p16

Topics: Animals; Anxiety; Astrocytes; Behavior, Animal; Brain; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Dasatinib; Diet, High-Fat; Disease Models, Animal; Female; Fibroblasts; Lipid Droplets; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Obesity; Quercetin; Tacrolimus

2019