ap-1903-reagent and Anemia

ap-1903-reagent has been researched along with Anemia* in 1 studies

Reviews

1 review(s) available for ap-1903-reagent and Anemia

Article	Year
Using gene transfer to circumvent off-target effects. Gene therapy, 2008, Volume: 15, Issue:10 Many recombinant growth factors have failed in clinical trials due to off-target effects. We describe a method for circumventing off-target effects that involves equipping cells with a conditionally active signaling protein that can be specifically activated by an exogenously administered synthetic ligand. We believe that this approach will have many applications in gene and cell therapy. Topics: Anemia; Animals; Cell Proliferation; Cell Transplantation; Gene Expression Regulation; Genetic Engineering; Genetic Therapy; Hematopoiesis; Humans; Neoplasms; Organic Chemicals; Receptors, Erythropoietin; Tacrolimus	2008

Article

Year

Using gene transfer to circumvent off-target effects.

Gene therapy, 2008, Volume: 15, Issue:10

Many recombinant growth factors have failed in clinical trials due to off-target effects. We describe a method for circumventing off-target effects that involves equipping cells with a conditionally active signaling protein that can be specifically activated by an exogenously administered synthetic ligand. We believe that this approach will have many applications in gene and cell therapy.

Topics: Anemia; Animals; Cell Proliferation; Cell Transplantation; Gene Expression Regulation; Genetic Engineering; Genetic Therapy; Hematopoiesis; Humans; Neoplasms; Organic Chemicals; Receptors, Erythropoietin; Tacrolimus

2008