Page last updated: 2024-10-22

antipyrine and Ulcer

antipyrine has been researched along with Ulcer in 2 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

Research Excerpts

ExcerptRelevanceReference
" The aims of this paper are to synthesize the mutual prodrugs of selected NSAIDs (Ketorolac, niflumic acid, tolfenamic acid) with propyphenazone, a study on their several physicochemical characters, hydrolysis kinetics, antiinflammatory, analgesic activity and ulcerogenicity."3.85Synthesis and Biological Evaluation of Mutual Prodrugs of Carboxylic Group Containing Some Non-Steroidal Anti-Inflammatory Drugs and Propyphenazone. ( Jain, S; Paliwal, M, 2017)
"Rats receiving intracolonic administration of indomethacin develop longitudinal ulcers on the mesenteric side of the small intestine that are similar to those seen in the acute phase of Crohn's disease."3.74Microcirculatory changes in experimental mesenteric longitudinal ulcers of the small intestine in rats. ( Haruma, K; Iida, M; Koga, H; Shimizu, K, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paliwal, M1
Jain, S1
Shimizu, K1
Koga, H1
Iida, M1
Haruma, K1

Other Studies

2 other studies available for antipyrine and Ulcer

ArticleYear
Synthesis and Biological Evaluation of Mutual Prodrugs of Carboxylic Group Containing Some Non-Steroidal Anti-Inflammatory Drugs and Propyphenazone.
    Current drug delivery, 2017, Volume: 14, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Carboxylic Acids; Dose-Res

2017
Microcirculatory changes in experimental mesenteric longitudinal ulcers of the small intestine in rats.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:11

    Topics: Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Cytokines; Disease Models

2007