antipyrine has been researched along with Thalassemia in 2 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum half-lives for antipyrine were normal or shorter than normal in 19 subjects between 7 and 23 yr of age with beta-thalassemia major." | 3.65 | Antipyrin clearance in homozygous beta-thalassemia. ( Canale, V; New, MI; Rifkind, AB, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Graziano, JH | 1 |
| Markenson, A | 1 |
| Miller, DR | 1 |
| Chang, H | 1 |
| Bestak, M | 1 |
| Meyers, P | 1 |
| Pisciotto, P | 1 |
| Rifkind, A | 1 |
| Rifkind, AB | 1 |
| Canale, V | 1 |
| New, MI | 1 |
1 trial available for antipyrine and Thalassemia
| Article | Year |
|---|---|
Chelation therapy in beta-thalassemia major. I. Intravenous and subcutaneous deferoxamine.
Topics: Adolescent; Adult; Age Factors; Antipyrine; Child; Child, Preschool; Deferoxamine; Dose-Response Rel | 1978 |
1 other study available for antipyrine and Thalassemia
| Article | Year |
|---|---|
Antipyrin clearance in homozygous beta-thalassemia.
Topics: Adolescent; Adult; Age Factors; Antipyrine; Child; Female; Half-Life; Humans; Male; Metabolic Cleara | 1976 |