antipyrine has been researched along with Substance Withdrawal Syndrome in 5 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The median difference of ICG clearance and all antipyrine pharmacokinetic parameters from smoking control was less than 13%, indicating that short-term smoking withdrawal had no effect large enough to be of clinical significance on hepatic blood flow or hepatic drug-metabolizing capacity." | 2.66 | The effect of acute withdrawal from cigarette smoking on indocyanine green and antipyrine clearance. ( Eldon, MA; Luecker, PW; MacGee, J; Ritschel, WA, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murphy, TL | 1 |
| McIvor, C | 1 |
| Yap, A | 1 |
| Cooksley, WG | 1 |
| Halliday, JW | 1 |
| Powell, LW | 1 |
| Patsalos, PN | 1 |
| Duncan, JS | 1 |
| Shorvon, SD | 1 |
| Eldon, MA | 1 |
| Luecker, PW | 1 |
| MacGee, J | 1 |
| Ritschel, WA | 1 |
| Evans, JI | 1 |
| Ogunremi, O | 1 |
| Ballinger, B | 1 |
| Browning, M | 1 |
| O'Malley, K | 1 |
| Stevenson, IH | 1 |
2 trials available for antipyrine and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
The effect of acute withdrawal from cigarette smoking on indocyanine green and antipyrine clearance.
Topics: Adult; Antipyrine; Humans; Indocyanine Green; Liver Circulation; Male; Smoking; Substance Withdrawal | 1987 |
Sleep and hypnotics: further experiments.
Topics: Adult; Amobarbital; Antipyrine; Chloral Hydrate; Diphenhydramine; Drug Tolerance; Humans; Male; Meth | 1970 |
3 other studies available for antipyrine and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
The effect of smoking on caffeine elimination: implications for its use as a semiquantitative test of liver function.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Fema | 1988 |
Effect of the removal of individual antiepileptic drugs on antipyrine kinetics, in patients taking polytherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Antipyrine; Drug Therapy, Combination; Enzyme Induction; H | 1988 |
Drug-metabolizing capacity in states of drug dependence and withdrawal.
Topics: Adult; Aged; Antipyrine; Barbiturates; Drug Tolerance; Female; Half-Life; Humans; Male; Methaqualone | 1972 |