antipyrine has been researched along with Subarachnoid Hemorrhage in 9 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is hypothesized that cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is induced by free radicals released from a subarachnoid clot." | 6.74 | Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage. ( Asano, K; Munakata, A; Nakano, T; Naraoka, M; Ohkuma, H; Shimamura, N, 2009) |
| "The degree of cerebral vasospasm was evaluated by measuring the diameter of each basilar artery, and the expression of Rho-kinase in the vascular wall was examined by western blotting." | 5.37 | Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model. ( Munakata, A; Ohkuma, H; Shimamura, N, 2011) |
| "A previous study indicated that diaspirin-crosslinked hemoglobin (DCLHb) decreases cerebral ischemia after subarachnoid hemorrhage." | 3.70 | Subarachnoid molecular hemoglobin after subarachnoid hemorrhage in rats: effect on the area of hypoperfusion. ( Cole, DJ; Cross, LM; Drummond, JC; McKay, LD; Patel, PM, 1998) |
| "It is hypothesized that cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is induced by free radicals released from a subarachnoid clot." | 2.74 | Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage. ( Asano, K; Munakata, A; Nakano, T; Naraoka, M; Ohkuma, H; Shimamura, N, 2009) |
| "Cerebral vasospasm is a major cause of cerebral ischemia and poor outcomes in the setting of aneurysmal subarachnoid hemorrhage (SAH)." | 2.44 | Novel treatments for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Lehmann, E; Sagher, O, 2008) |
| "The degree of cerebral vasospasm was evaluated by measuring the diameter of each basilar artery, and the expression of Rho-kinase in the vascular wall was examined by western blotting." | 1.37 | Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model. ( Munakata, A; Ohkuma, H; Shimamura, N, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagashima, H | 1 |
| Miwa, T | 1 |
| Horiguchi, T | 1 |
| Tomio, R | 1 |
| Nakagawa, Y | 1 |
| Yoshida, K | 1 |
| Povlsen, GK | 1 |
| Johansson, SE | 1 |
| Larsen, CC | 1 |
| Samraj, AK | 1 |
| Edvinsson, L | 1 |
| Lehmann, E | 1 |
| Sagher, O | 1 |
| Munakata, A | 2 |
| Ohkuma, H | 2 |
| Nakano, T | 1 |
| Shimamura, N | 2 |
| Asano, K | 1 |
| Naraoka, M | 1 |
| Gao, Y | 1 |
| Ding, XS | 1 |
| Xu, S | 1 |
| Wang, W | 1 |
| Zuo, QL | 1 |
| Kuai, F | 1 |
| Cole, DJ | 1 |
| McKay, LD | 1 |
| Drummond, JC | 1 |
| Patel, PM | 1 |
| Cross, LM | 1 |
| Delgado, TJ | 2 |
| Arbab, MA | 1 |
| Diemer, NH | 2 |
| Svendgaard, NA | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Nerve Growth Factor or Edaravone on Alcohol-induced Brain Injury[NCT03968042] | Phase 2 | 150 participants (Anticipated) | Interventional | 2019-06-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for antipyrine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Novel treatments for cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Edaravone; Fibrinolytic Agents; Free Radical Scavenge | 2008 |
1 trial available for antipyrine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage.
Topics: Antipyrine; Cerebral Infarction; Comorbidity; Edaravone; Female; Free Radical Scavengers; Humans; Ja | 2009 |
7 other studies available for antipyrine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Hyperperfusion after Clipping of Aneurysm: A Rare Entity.
Topics: Aged; Aneurysm, Ruptured; Angiography, Digital Subtraction; Antipyrine; Cerebral Angiography; Cerebr | 2018 |
Early events triggering delayed vasoconstrictor receptor upregulation and cerebral ischemia after subarachnoid hemorrhage.
Topics: Analysis of Variance; Animals; Antipyrine; Area Under Curve; Blood Pressure; Brain Ischemia; Butadie | 2013 |
Neuroprotective effects of edaravone on early brain injury in rats after subarachnoid hemorrhage.
Topics: Animals; Antipyrine; Blotting, Western; Brain Injuries; Edaravone; Immunohistochemistry; Male; Malon | 2009 |
Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model.
Topics: Animals; Antipyrine; Basilar Artery; Disease Models, Animal; Edaravone; Free Radical Scavengers; Gen | 2011 |
Subarachnoid molecular hemoglobin after subarachnoid hemorrhage in rats: effect on the area of hypoperfusion.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Antipyrine; Aspirin; Blood; Blood Substitute | 1998 |
Subarachnoid hemorrhage in the rat: cerebral blood flow and glucose metabolism during the late phase of cerebral vasospasm.
Topics: Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Deox | 1986 |
Subarachnoid hemorrhage in the rat: cerebral blood flow and glucose metabolism after selective lesions of the catecholamine systems in the brainstem.
Topics: Animals; Antipyrine; Autoradiography; Brain; Brain Stem; Carbon Radioisotopes; Catecholamines; Cereb | 1986 |