antipyrine has been researched along with Status Epilepticus in 5 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Edaravone (MCI-186) is a newly developed antioxidative radical scavenger for the treatment of acute cerebral infarction, exerting neuroprotective effects against ischemic insult." | 5.35 | Neuroprotective effects of edaravone, a free radical scavenger, on the rat hippocampus after pilocarpine-induced status epilepticus. ( Abe, T; Anan, M; Fujiki, M; Kamida, T; Kobayashi, H; Ooba, H, 2009) |
| "The edaravone pretreatment group received edaravone by intraperitoneal injection once daily three days before convulsion induction." | 1.36 | [Protection of edaravone on neurons and its effects on the expression of interleukin-lbeta in juvenile rat hippocampus following status convulsion]. ( Li, GQ; Wang, HP, 2010) |
| "Edaravone (MCI-186) is a newly developed antioxidative radical scavenger for the treatment of acute cerebral infarction, exerting neuroprotective effects against ischemic insult." | 1.35 | Neuroprotective effects of edaravone, a free radical scavenger, on the rat hippocampus after pilocarpine-induced status epilepticus. ( Abe, T; Anan, M; Fujiki, M; Kamida, T; Kobayashi, H; Ooba, H, 2009) |
| "The edaravone-treated SC group demonstrated less severe apoptosis than the untreated SC group." | 1.35 | [Effects of edaravone on IRE1 mRNA expression and neuronal apoptosis in the hippocampus of rats with status convulsivus]. ( Deng, XL; Jiao, Y; Li, GQ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamida, T | 1 |
| Fujiki, M | 1 |
| Ooba, H | 1 |
| Anan, M | 1 |
| Abe, T | 1 |
| Kobayashi, H | 1 |
| Jiao, Y | 1 |
| Deng, XL | 1 |
| Li, GQ | 2 |
| Wang, HP | 1 |
| de Vasconcelos, AP | 1 |
| Bouilleret, V | 1 |
| Riban, V | 1 |
| Wasterlain, C | 1 |
| Nehlig, A | 1 |
| Miyamoto, R | 1 |
| Shimakawa, S | 1 |
| Suzuki, S | 1 |
| Ogihara, T | 1 |
| Tamai, H | 1 |
5 other studies available for antipyrine and Status Epilepticus
| Article | Year |
|---|---|
Neuroprotective effects of edaravone, a free radical scavenger, on the rat hippocampus after pilocarpine-induced status epilepticus.
Topics: Animals; Antipyrine; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Edaravone | 2009 |
[Effects of edaravone on IRE1 mRNA expression and neuronal apoptosis in the hippocampus of rats with status convulsivus].
Topics: Animals; Antipyrine; Apoptosis; Disease Models, Animal; Edaravone; Hippocampus; In Situ Nick-End Lab | 2009 |
[Protection of edaravone on neurons and its effects on the expression of interleukin-lbeta in juvenile rat hippocampus following status convulsion].
Topics: Animals; Antipyrine; Edaravone; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Interl | 2010 |
Role of nitric oxide in cerebral blood flow changes during kainate seizures in mice: genetic and pharmacological approaches.
Topics: Animals; Antipyrine; Brain; Cerebral Cortex; Cerebrovascular Circulation; Convulsants; Disease Model | 2005 |
Edaravone prevents kainic acid-induced neuronal death.
Topics: Aldehydes; Animals; Antipyrine; Brain; Cell Death; Disease Models, Animal; Down-Regulation; Edaravon | 2008 |