Page last updated: 2024-10-22

antipyrine and Schizophrenia

antipyrine has been researched along with Schizophrenia in 4 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"Antipyrine half-life was measured in the 12 patients while they continued to receive the drug."1.26Induction of microsomal enzyme activity by flupenthixol in chronic schizophrenics. ( King, DJ; McDevitt, DG; Salem, SA, 1982)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Salem, SA1
King, DJ1
McDevitt, DG1
Petruch, F1
Schüppel, R1
Breyer, U1
Kolakowska, T1
Franklin, M1
Alapin, B1
Stevenson, IH1
O'Malley, K1
Turnbull, MJ1
Ballinger, BR1

Other Studies

4 other studies available for antipyrine and Schizophrenia

ArticleYear
Induction of microsomal enzyme activity by flupenthixol in chronic schizophrenics.
    Psychopharmacology, 1982, Volume: 78, Issue:2

    Topics: Adult; Aged; Antipyrine; Chronic Disease; Enzyme Induction; Flupenthixol; Half-Life; Humans; Microso

1982
[Changes in drug elimination under the influence of perazine therapy (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:6

    Topics: Antipsychotic Agents; Antipyrine; Humans; Kinetics; Liver; Male; Perazine; Schizophrenia

1976
Effect of long-term phenothiazine treatment on drug metabolism.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:1

    Topics: Adult; Aged; Antipyrine; Female; Half-Life; Humans; Liver; Male; Middle Aged; Phenothiazines; Placeb

1975
The effect of chlorpromazine on drug metabolism.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:7

    Topics: Adult; Aged; Animals; Antipyrine; Barbiturates; Biotransformation; Chlorpromazine; Enzyme Induction;

1972