antipyrine has been researched along with Pulmonary Fibrosis in 6 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we aimed to investigate the effects of diterpene ginkgolides meglumine injection (DGMI) on paraquat (PQ)-induced lung injury and pulmonary fibrosis in rats." | 7.88 | Diterpene ginkgolides meglumine injection protects against paraquat-induced lung injury and pulmonary fibrosis in rats. ( Li, GP; Li, L; Liu, Q; Wang, ZZ; Xiao, W; Xu, ZL; Yang, H; Zhou, J; Zong, SB, 2018) |
| " In this study, we evaluated whether edaravone could protect against lung injury and pulmonary fibrosis in paraquat-treated rats." | 7.77 | Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat? ( Qian, X; Sun, H; Yang, L; Zhi, Q, 2011) |
| " The aim of this study was to examine the effect of edaravone, a free radical scavenger, on the development of fibrosis and autoimmunity in two different mouse models of SSc." | 7.77 | The specific free radical scavenger edaravone suppresses fibrosis in the bleomycin-induced and tight skin mouse models of systemic sclerosis. ( Asano, Y; Iwata, Y; Kadono, T; Ogawa, A; Ogawa, F; Sato, S; Shimizu, K; Takenaka, M; Yanaba, K; Yoshizaki, A, 2011) |
| "Pulmonary fibrosis is responsible for the both short-term and long-term outcomes in patients with acute respiratory distress syndrome (ARDS)." | 5.48 | Edaravone attenuates lipopolysaccharide-induced acute respiratory distress syndrome associated early pulmonary fibrosis via amelioration of oxidative stress and transforming growth factor-β1/Smad3 signaling. ( Chen, G; Lai, R; Liang, Z; Su, X; Wang, X, 2018) |
| "In this study, we aimed to investigate the effects of diterpene ginkgolides meglumine injection (DGMI) on paraquat (PQ)-induced lung injury and pulmonary fibrosis in rats." | 3.88 | Diterpene ginkgolides meglumine injection protects against paraquat-induced lung injury and pulmonary fibrosis in rats. ( Li, GP; Li, L; Liu, Q; Wang, ZZ; Xiao, W; Xu, ZL; Yang, H; Zhou, J; Zong, SB, 2018) |
| " In this study, we evaluated whether edaravone could protect against lung injury and pulmonary fibrosis in paraquat-treated rats." | 3.77 | Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat? ( Qian, X; Sun, H; Yang, L; Zhi, Q, 2011) |
| " The aim of this study was to examine the effect of edaravone, a free radical scavenger, on the development of fibrosis and autoimmunity in two different mouse models of SSc." | 3.77 | The specific free radical scavenger edaravone suppresses fibrosis in the bleomycin-induced and tight skin mouse models of systemic sclerosis. ( Asano, Y; Iwata, Y; Kadono, T; Ogawa, A; Ogawa, F; Sato, S; Shimizu, K; Takenaka, M; Yanaba, K; Yoshizaki, A, 2011) |
| "Pulmonary fibrosis is responsible for the both short-term and long-term outcomes in patients with acute respiratory distress syndrome (ARDS)." | 1.48 | Edaravone attenuates lipopolysaccharide-induced acute respiratory distress syndrome associated early pulmonary fibrosis via amelioration of oxidative stress and transforming growth factor-β1/Smad3 signaling. ( Chen, G; Lai, R; Liang, Z; Su, X; Wang, X, 2018) |
| "Lung injury was induced in female ICR mice by intratracheal instillation of 5 mg x kg(-1) of BLM." | 1.35 | Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice. ( Bando, M; Gejyo, F; Hosono, T; Ishii, Y; Ohno, S; Sugiyama, Y; Suzuki, E; Tajima, S; Takada, T; Yamasawa, H, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Lai, R | 1 |
| Su, X | 1 |
| Chen, G | 1 |
| Liang, Z | 1 |
| Li, GP | 1 |
| Yang, H | 1 |
| Zong, SB | 1 |
| Liu, Q | 1 |
| Li, L | 1 |
| Xu, ZL | 1 |
| Zhou, J | 1 |
| Wang, ZZ | 1 |
| Xiao, W | 1 |
| Tajima, S | 1 |
| Bando, M | 1 |
| Ishii, Y | 1 |
| Hosono, T | 1 |
| Yamasawa, H | 1 |
| Ohno, S | 1 |
| Takada, T | 1 |
| Suzuki, E | 1 |
| Gejyo, F | 1 |
| Sugiyama, Y | 1 |
| Fujita, M | 1 |
| Mizuta, Y | 1 |
| Ikegame, S | 1 |
| Ouchi, H | 1 |
| Ye, Q | 1 |
| Harada, E | 1 |
| Inoshima, I | 1 |
| Yoshimi, M | 1 |
| Watanabe, K | 1 |
| Nakanishi, Y | 1 |
| Zhi, Q | 1 |
| Sun, H | 1 |
| Qian, X | 1 |
| Yang, L | 1 |
| Yoshizaki, A | 1 |
| Yanaba, K | 1 |
| Ogawa, A | 1 |
| Iwata, Y | 1 |
| Ogawa, F | 1 |
| Takenaka, M | 1 |
| Shimizu, K | 1 |
| Asano, Y | 1 |
| Kadono, T | 1 |
| Sato, S | 1 |
6 other studies available for antipyrine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Edaravone attenuates lipopolysaccharide-induced acute respiratory distress syndrome associated early pulmonary fibrosis via amelioration of oxidative stress and transforming growth factor-β1/Smad3 signaling.
Topics: Animals; Antipyrine; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Lipopolys | 2018 |
Diterpene ginkgolides meglumine injection protects against paraquat-induced lung injury and pulmonary fibrosis in rats.
Topics: Acute Lung Injury; Animals; Antipyrine; Dose-Response Relationship, Drug; Edaravone; Ginkgolides; In | 2018 |
Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice.
Topics: Animals; Antipyrine; Bleomycin; Bronchoalveolar Lavage Fluid; Dinoprostone; Edaravone; Female; Free | 2008 |
Biphasic effects of free radical scavengers against bleomycin-induced pulmonary fibrosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antipyrine; Apoptosis; Bleomycin; Bronchi; Bronchoalveolar Lav | 2008 |
Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat?
Topics: Animals; Antidotes; Antipyrine; Bronchoalveolar Lavage Fluid; Edaravone; Herbicides; Hydroxyproline; | 2011 |
The specific free radical scavenger edaravone suppresses fibrosis in the bleomycin-induced and tight skin mouse models of systemic sclerosis.
Topics: Animals; Antipyrine; Bleomycin; Disease Models, Animal; Edaravone; Fibrosis; Free Radical Scavengers | 2011 |