antipyrine has been researched along with Parkinsonian Disorders in 2 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Edaravone is a powerful free radical scavenger used in clinical treatment for cerebral ischemic stroke." | 1.39 | Edaravone prevents neurotoxicity of mutant L166P DJ-1 in Parkinson's disease. ( Li, B; Xu, Z; Yu, D, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, B | 1 |
| Yu, D | 1 |
| Xu, Z | 1 |
| Xiong, N | 1 |
| Xiong, J | 1 |
| Khare, G | 1 |
| Chen, C | 1 |
| Huang, J | 1 |
| Zhao, Y | 1 |
| Zhang, Z | 1 |
| Qiao, X | 1 |
| Feng, Y | 1 |
| Reesaul, H | 1 |
| Zhang, Y | 1 |
| Sun, S | 1 |
| Lin, Z | 1 |
| Wang, T | 1 |
2 other studies available for antipyrine and Parkinsonian Disorders
| Article | Year |
|---|---|
Edaravone prevents neurotoxicity of mutant L166P DJ-1 in Parkinson's disease.
Topics: Animals; Antipyrine; Apoptosis; Cell Line, Tumor; Edaravone; Free Radical Scavengers; Mice; Mitochon | 2013 |
Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease.
Topics: Animals; Antipyrine; bcl-2-Associated X Protein; Behavior, Animal; Dopamine; Edaravone; Free Radical | 2011 |