antipyrine has been researched along with Parkinson Disease in 1 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Edaravone might be a hopeful therapeutic option for PD, although the high therapeutic dosage remains to be solved for the clinical application." | 1.35 | Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons. ( Agari, T; Baba, T; Date, I; Jing, M; Kameda, M; Leung, H; Matsui, T; Miyoshi, Y; Morimoto, T; Muraoka, K; Shingo, T; Tajiri, N; Uozumi, T; Wang, F; Yasuhara, T; Yuan, WJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, WJ | 1 |
| Yasuhara, T | 1 |
| Shingo, T | 1 |
| Muraoka, K | 1 |
| Agari, T | 1 |
| Kameda, M | 1 |
| Uozumi, T | 1 |
| Tajiri, N | 1 |
| Morimoto, T | 1 |
| Jing, M | 1 |
| Baba, T | 1 |
| Wang, F | 1 |
| Leung, H | 1 |
| Matsui, T | 1 |
| Miyoshi, Y | 1 |
| Date, I | 1 |
1 other study available for antipyrine and Parkinson Disease
| Article | Year |
|---|---|
Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons.
Topics: Animals; Antipyrine; Cell Survival; Cells, Cultured; Dopamine; Edaravone; Female; Mice; Mice, Inbred | 2008 |