antipyrine has been researched along with Paraplegia in 4 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Paraplegia: Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a rabbit model with aortic clamping up to 30 minutes, which consistently produces complete paraplegia in rabbits, spinal cord damage was partially reduced by topical cooling with transvertebral cooling pads or the injection of edaravone into the clamped segment of aorta, but was more effectively protected by a combined use of these two strategies." | 3.77 | New method for absolute spinal cord ischemia protection in rabbits. ( Herlambang, B; Hiyama, E; Mizukami, T; Orihashi, K; Sueda, T; Takahashi, S; Uchida, N, 2011) |
| "Paraplegia is a serious complication of operations on the thoracic and thoracoabdominal aorta." | 1.32 | MCI-186 reduces oxidative cellular damage and increases DNA repair function in the rabbit spinal cord after transient ischemia. ( Abe, K; Itoyama, Y; Sakurai, M; Tabayashi, K; Takahashi, G, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herlambang, B | 1 |
| Orihashi, K | 1 |
| Mizukami, T | 1 |
| Takahashi, S | 1 |
| Uchida, N | 1 |
| Hiyama, E | 1 |
| Sueda, T | 1 |
| Takahashi, G | 1 |
| Sakurai, M | 1 |
| Abe, K | 1 |
| Itoyama, Y | 1 |
| Tabayashi, K | 1 |
| Bingham, WG | 1 |
| Goldman, H | 1 |
| Friedman, SJ | 1 |
| Murphy, S | 1 |
| Yashon, D | 1 |
| Hunt, WE | 1 |
| Marshall, LF | 1 |
| Durity, F | 1 |
| Lounsbury, R | 1 |
| Graham, DI | 1 |
| Welsh, F | 1 |
| Langfitt, TW | 1 |
4 other studies available for antipyrine and Paraplegia
| Article | Year |
|---|---|
New method for absolute spinal cord ischemia protection in rabbits.
Topics: Animals; Antipyrine; Aorta; Biomarkers; Combined Modality Therapy; Constriction; Disease Models, Ani | 2011 |
MCI-186 reduces oxidative cellular damage and increases DNA repair function in the rabbit spinal cord after transient ischemia.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antipyrine; Apoptosis; Ataxia; Biomarkers; Cell Count; Cell Nu | 2004 |
Blood flow in normal and injured monkey spinal cord.
Topics: Animals; Antipyrine; Autoradiography; Carbon Dioxide; Carbon Radioisotopes; Cardiac Output; Cats; Ch | 1975 |
Experimental cerebral oligemia and ischemia produced by intracranial hypertension. Part 1: Pathophysiology, electroencephalography, cerebral blood flow, blood-brain barrier, and neurological function.
Topics: Animals; Antipyrine; Autoradiography; Blood Pressure; Blood-Brain Barrier; Brain; Carbon Radioisotop | 1975 |