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antipyrine and Pancreatic Neoplasms

antipyrine has been researched along with Pancreatic Neoplasms in 6 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
" Oxidative drug metabolizing capacity has been assessed by oral antipyrine and/or theophylline tests in consecutive patients with chronic pancreatitis (CP; alcoholic 24, idiopathic 47), acute pancreatitis (AP; 28) and pancreatic cancer (CA; 11)."5.06Factors contributing to the accelerated clearance of theophylline and antipyrine in adults with exocrine pancreatic disease. ( Acheson, DW; Braganza, JM; Houston, JB; Hunt, LP; Rose, P, 1989)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Higuchi, T2
Nakamura, T2
Uchino, H2
Priebe, TS1
Atkinson, EN1
Pan, BF1
Nelson, JA1
Acheson, DW2
Hunt, LP1
Rose, P2
Houston, JB2
Braganza, JM2
Christen, TP1

Trials

1 trial available for antipyrine and Pancreatic Neoplasms

ArticleYear
Factors contributing to the accelerated clearance of theophylline and antipyrine in adults with exocrine pancreatic disease.
    Clinical science (London, England : 1979), 1989, Volume: 76, Issue:4

    Topics: Adult; Aged; Alcohol Drinking; Antipyrine; Enzyme Induction; Female; Humans; Male; Metabolic Clearan

1989

Other Studies

5 other studies available for antipyrine and Pancreatic Neoplasms

ArticleYear
Antipyrine metabolism in cancer patients.
    Cancer, 1980, Volume: 45, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Antipyrine; Half-Life; Humans; Microsomes, Liver; Middle Aged; N

1980
Antipyrine metabolism in cancer patients.
    Experientia, 1980, Feb-15, Volume: 36, Issue:2

    Topics: Adult; Aged; Antipyrine; Bilirubin; Creatinine; Humans; Kinetics; Middle Aged; Pancreatic Neoplasms;

1980
Intrinsic resistance to anticancer agents in the murine pancreatic adenocarcinoma PANC02.
    Cancer chemotherapy and pharmacology, 1992, Volume: 29, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antipyrine; ATP Binding Cassette Transporter, Subfam

1992
Induction of cytochromes P-450 in pancreatic disease: consequence, coincidence or cause?
    Clinica chimica acta; international journal of clinical chemistry, 1985, Dec-13, Volume: 153, Issue:2

    Topics: Adolescent; Adult; Antipyrine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Half-Life;

1985
[The technique of pancreato-cholangiography (PCG)].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1973, Volume: 118, Issue:2

    Topics: Ampulla of Vater; Analgesics; Antipyrine; Cholangiography; Duodenal Neoplasms; Endoscopy; Gallstones

1973