antipyrine has been researched along with Otitis Media in 9 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Otitis Media: Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0." | 9.05 | Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985) |
| "To determine the efficacy of Auralgan otic solution (combination product of antipyrine, benzocaine, and glycerin) compared with an olive oil placebo in the management of moderate to severe ear pain in children with acute otitis media (AOM)." | 5.08 | Efficacy of Auralgan for treating ear pain in children with acute otitis media. ( Hoberman, A; Paradise, JL; Reynolds, EA; Urkin, J, 1997) |
| "In a study including a total of 175 children, ranging in age from 3 months to 3 years and suffering from otitis media, the analgesic effect of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol) syrup was compared with that of lidocaine 0." | 5.05 | Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. ( Michos, N; Stocker, H; Weippl, G, 1985) |
| "Results of the use of ampicillin, penicillin G and symptomatic therapy in the treatment of acute otitis media in 142 children were compared." | 3.65 | Treatment of acute otitis media: a controlled study of 142 children. ( Jones, RH; Laxdal, OE; Merida, J, 1970) |
| "A dose-dependent toxic effect of Auralgan was noted on cultured cells." | 1.42 | Assessment of ototoxicity of intratympanic administration of Auralgan in a chinchilla animal model. ( Bezdjian, A; Daniel, SJ; Mujica-Mota, MA; Salehi, P; Schermbrucker, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mujica-Mota, MA | 1 |
| Bezdjian, A | 1 |
| Salehi, P | 1 |
| Schermbrucker, J | 1 |
| Daniel, SJ | 1 |
| Adam, D | 1 |
| Federspil, P | 1 |
| Lukes, M | 1 |
| Petrowicz, O | 1 |
| McWilliams, DB | 1 |
| Jacobson, RM | 1 |
| Van Houten, HK | 1 |
| Naessens, JM | 1 |
| Ytterberg, KL | 1 |
| Berman, S | 1 |
| Hoberman, A | 1 |
| Paradise, JL | 1 |
| Reynolds, EA | 1 |
| Urkin, J | 1 |
| Woldman, S | 1 |
| Weippl, G | 1 |
| Michos, N | 1 |
| Stocker, H | 1 |
| Laxdal, OE | 1 |
| Merida, J | 1 |
| Jones, RH | 1 |
| Busmann, GJ | 1 |
3 trials available for antipyrine and Otitis Media
| Article | Year |
|---|---|
Therapeutic properties and tolerance of procaine and phenazone containing ear drops in infants and very young children.
Topics: Aging; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Child; Child, Presch | 2009 |
Efficacy of Auralgan for treating ear pain in children with acute otitis media.
Topics: Acute Disease; Adolescent; Adult; Antipyrine; Benzocaine; Child; Child, Preschool; Double-Blind Meth | 1997 |
Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Child, Preschool; Drug Combinations; Humans; In | 1985 |
6 other studies available for antipyrine and Otitis Media
| Article | Year |
|---|---|
Assessment of ototoxicity of intratympanic administration of Auralgan in a chinchilla animal model.
Topics: Animals; Antipyrine; Auditory Threshold; Benzocaine; Cells, Cultured; Chinchilla; Disease Models, An | 2015 |
A program of anticipatory guidance for the prevention of emergency department visits for ear pain.
Topics: Antipyrine; Benzocaine; Child; Child, Preschool; Diagnosis, Differential; Earache; Emergency Service | 2008 |
Otitis media, shared decision making, and enhancing value in pediatric practice.
Topics: Antipyrine; Benzocaine; Child; Child, Preschool; Decision Making; Diagnosis, Differential; Earache; | 2008 |
Treating ear pain in children with acute otitis media.
Topics: Acute Disease; Antipyrine; Benzocaine; Child; Drug Combinations; Ear; Earache; Humans; Instillation, | 1998 |
Treatment of acute otitis media: a controlled study of 142 children.
Topics: Acute Disease; Adolescent; Ampicillin; Antipyrine; Aspirin; Benzocaine; Child; Child, Preschool; Hum | 1970 |
[Local therapy of diseases of the middle ear].
Topics: Antipyrine; Chloramphenicol; Dexamethasone; Humans; Otitis Media; Pantothenic Acid; Tetracaine | 1967 |