antipyrine has been researched along with Osteomalacia in 2 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Osteomalacia: Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Antipyrine t1/2 did not distinguish epileptics with osteomalacia from other epileptic patients and half-lives were similar in patients treated with phenytoin and a barbiturate to those in patients on phenytoin alone." | 3.66 | Antiopyrine half-life as a measure of hepatic enzyme induction: clinical applications in a chronic epileptic population. ( Byrne, E; Frewin, DB; Hallpike, JF; Harman, AW, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fraser, HS | 1 |
| Thompson, D | 1 |
| Khan, C | 1 |
| Byrne, E | 1 |
| Harman, AW | 1 |
| Frewin, DB | 1 |
| Hallpike, JF | 1 |
2 other studies available for antipyrine and Osteomalacia
| Article | Year |
|---|---|
Clinical application of antipyrine half life in saliva in a patient with osteomalacia.
Topics: Aged; Antipyrine; Barbiturates; Enzyme Induction; Female; Half-Life; Humans; Osteomalacia; Spironola | 1976 |
Antiopyrine half-life as a measure of hepatic enzyme induction: clinical applications in a chronic epileptic population.
Topics: Adult; Antipyrine; Barbiturates; Enzyme Induction; Epilepsy; Female; Half-Life; Humans; Male; Micros | 1979 |