antipyrine has been researched along with MPTP Neurotoxicity Syndrome in 2 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with edaravone (1 and 3 mg/kg i." | 1.34 | Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum. ( Ago, Y; Baba, A; Ishihara, K; Kawasaki, T; Matsuda, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yokoyama, H | 1 |
| Yano, R | 1 |
| Aoki, E | 1 |
| Kato, H | 1 |
| Araki, T | 1 |
| Kawasaki, T | 1 |
| Ishihara, K | 1 |
| Ago, Y | 1 |
| Baba, A | 1 |
| Matsuda, T | 1 |
2 other studies available for antipyrine and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Comparative pharmacological study of free radical scavenger, nitric oxide synthase inhibitor, nitric oxide synthase activator and cyclooxygenase inhibitor against MPTP neurotoxicity in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipyrine; Cyclooxygenase Inhibitors; Dopamine; Edaravone; | 2008 |
Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antipyrine; Brain; Corpus Striatum; Dopamine; Edaravone; Free | 2007 |