antipyrine has been researched along with Liver Failure, Acute in 3 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The edaravone-treated animals demonstrated an increased number of engrafted donor hepatocytes in the liver." | 1.40 | Effects of edaravone, a radical scavenger, on hepatocyte transplantation. ( Fox, IJ; Hayashi, C; Hiramatsu, N; Horiguchi, A; Ito, M; Ito, R; Murakumo, A; Yamamoto, N, 2014) |
| "Fulminant hepatic failure is a serious disease that has a poor cure rate unless liver transplantation is performed." | 1.35 | Edaravone prevents Fas-induced fulminant hepatic failure in mice by regulating mitochondrial Bcl-xL and Bax. ( Kamiyama, Y; Kwon, AH; Miyasou, T; Okumura, T; Qiu, Z; Tsuji, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, C | 1 |
| Ito, M | 1 |
| Ito, R | 1 |
| Murakumo, A | 1 |
| Yamamoto, N | 1 |
| Hiramatsu, N | 1 |
| Fox, IJ | 1 |
| Horiguchi, A | 1 |
| Miyasou, T | 1 |
| Kwon, AH | 1 |
| Tsuji, K | 1 |
| Qiu, Z | 1 |
| Okumura, T | 1 |
| Kamiyama, Y | 1 |
| Matthew, HW | 1 |
| Basu, S | 1 |
| Peterson, WD | 1 |
| Salley, SO | 1 |
| Klein, MD | 1 |
3 other studies available for antipyrine and Liver Failure, Acute
| Article | Year |
|---|---|
Effects of edaravone, a radical scavenger, on hepatocyte transplantation.
Topics: Animals; Antipyrine; Apoptosis; Edaravone; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Hepato | 2014 |
Edaravone prevents Fas-induced fulminant hepatic failure in mice by regulating mitochondrial Bcl-xL and Bax.
Topics: Animals; Antipyrine; bcl-2-Associated X Protein; bcl-X Protein; Edaravone; fas Receptor; Female; Fre | 2008 |
Performance of plasma-perfused, microencapsulated hepatocytes: prospects for extracorporeal liver support.
Topics: Albumins; Animals; Antipyrine; Carboxymethylcellulose Sodium; Cells, Cultured; Chitin; Chitosan; Cho | 1993 |