antipyrine has been researched along with Leukemia in 3 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| " It should be taken into account when dosing drugs which are metabolized as markers of the liver metabolic efficiency like phenazone and sulphadimidine." | 2.68 | [Evaluation of phenazone oxidation and sulfadimidine acetylation in patients with hematologic neoplasms]. ( Kotlarek-Haus, S; Milejski, P; Orzechowska-Juzwenko, K; Urbaniak-Kujda, D; Usnarska-Zubkiewicz, L; Wiela-Hojeńska, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosu, T | 1 |
| Negoiu, M | 1 |
| Pasculescu, S | 1 |
| Pahontu, E | 1 |
| Poirier, D | 1 |
| Gulea, A | 1 |
| Wiela-Hojeńska, A | 1 |
| Milejski, P | 1 |
| Orzechowska-Juzwenko, K | 1 |
| Usnarska-Zubkiewicz, L | 1 |
| Urbaniak-Kujda, D | 1 |
| Kotlarek-Haus, S | 1 |
| Rall, DP | 1 |
1 trial available for antipyrine and Leukemia
| Article | Year |
|---|---|
[Evaluation of phenazone oxidation and sulfadimidine acetylation in patients with hematologic neoplasms].
Topics: Acetylation; Adolescent; Adult; Aged; Antipyrine; Disease Susceptibility; Female; Hodgkin Disease; H | 1997 |
2 other studies available for antipyrine and Leukemia
| Article | Year |
|---|---|
Metal-based biologically active agents: Synthesis, characterization, antibacterial and antileukemia activity evaluation of Cu(II), V(IV) and Ni(II) complexes with antipyrine-derived compounds.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antipyrine; Bacteria; Copper; Fungi; HL-60 Ce | 2010 |
Conference on obstacles to the control of acute leukemia. Experimental studies of the blood-brain barrier.
Topics: Aminohippuric Acids; Antipyrine; Blood-Brain Barrier; Child; Humans; Hydrocortisone; Leukemia; Male; | 1965 |