Page last updated: 2024-10-22

antipyrine and Kwashiorkor

antipyrine has been researched along with Kwashiorkor in 2 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Kwashiorkor: A syndrome produced by severe protein deficiency, characterized by retarded growth, changes in skin and hair pigment, edema, and pathologic changes in the liver, including fatty infiltration, necrosis, and fibrosis. The word is a local name in Gold Coast, Africa, meaning displaced child. Although first reported from Africa, kwashiorkor is now known throughout the world, but mainly in the tropics and subtropics. It is considered to be related to marasmus. (From Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" Microsomal oxidation as measured by antipyrine half-life and clearance was shown to be depressed in the acute phase of malnutrition (T 1/2 = 7."5.26Antipyrine pharmacokinetics and D-glucaric excretion in kwashiorkor. ( Buchanan, N; Davis, MD; Eyberg, C, 1979)
" Microsomal oxidation as measured by antipyrine half-life and clearance was shown to be depressed in the acute phase of malnutrition (T 1/2 = 7."1.26Antipyrine pharmacokinetics and D-glucaric excretion in kwashiorkor. ( Buchanan, N; Davis, MD; Eyberg, C, 1979)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buchanan, N2
Davis, M1
Danhof, M1
Breimer, DD1
Eyberg, C1
Davis, MD1

Other Studies

2 other studies available for antipyrine and Kwashiorkor

ArticleYear
Antipyrine metabolite formation in children in the acute phase of malnutrition and after recovery.
    British journal of clinical pharmacology, 1980, Volume: 10, Issue:4

    Topics: Acute Disease; Antipyrine; Child, Preschool; Glucuronates; Humans; Infant; Kinetics; Kwashiorkor

1980
Antipyrine pharmacokinetics and D-glucaric excretion in kwashiorkor.
    The American journal of clinical nutrition, 1979, Volume: 32, Issue:12

    Topics: Antipyrine; Glucaric Acid; Glucuronates; Half-Life; Humans; Infant; Kinetics; Kwashiorkor; Microsome

1979