antipyrine has been researched along with Kidney Failure, Chronic in 13 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacokinetic variable values in elderly subjects did not differ in a clinically significant manner from those in younger subjects." | 1.28 | Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when coadministered with NSAID or antipyrine, propranolol or diazepam. ( Karim, A; Nicholson, PA; Smith, M, 1990) |
| "Antipyrine was given orally to five patients with Chronic renal failure and nine normal subjects." | 1.26 | Antipyrine kinetics in Nigerian women in chronic renal failure. ( Iyun, AO; Tucker, GT, 1982) |
| "Antipyrine (10 mg/kg) was given orally and assayed in saliva by gas-liquid chromatography." | 1.26 | Salivary antipyrine kinetics in hepatic and renal disease and in patients on anticonvulsant therapy. ( Clarkson, AR; Frewin, DB; Harman, AW; Penhall, RK; Phillips, PJ; Priestly, BG, 1977) |
| "1." | 1.25 | The plasma half-life of antipyrine in chromic uraemic and normal subjects. ( Harber, MJ; Maddocks, JL; Wake, CJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iyun, AO | 1 |
| Tucker, GT | 1 |
| Pollack, GM | 1 |
| Shen, DD | 1 |
| Lanchote, VL | 2 |
| Ping, WC | 2 |
| Santos, SR | 2 |
| de Fijter, WM | 1 |
| de Fijter, CW | 1 |
| Oe, PL | 1 |
| ter Wee, PM | 1 |
| Donker, AJ | 1 |
| Harman, AW | 1 |
| Penhall, RK | 1 |
| Priestly, BG | 1 |
| Frewin, DB | 1 |
| Phillips, PJ | 1 |
| Clarkson, AR | 1 |
| van Peer, AP | 1 |
| Belpaire, FM | 1 |
| Bogaert, MG | 1 |
| Gibaldi, M | 1 |
| Maddocks, JL | 1 |
| Wake, CJ | 1 |
| Harber, MJ | 1 |
| Nicholson, PA | 1 |
| Karim, A | 1 |
| Smith, M | 1 |
| Tvedegaard, E | 1 |
| Poulsen, HE | 1 |
| Vilstrup, H | 1 |
| Thomsen, HK | 1 |
| Teunissen, MW | 1 |
| Kampf, D | 1 |
| Roots, I | 1 |
| Vermeulen, NP | 1 |
| Breimer, DD | 1 |
| Bengtsson, U | 1 |
1 trial available for antipyrine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Influence of renal failure on cytochrome P450 activity in hypertensive patients using a "cocktail" of antipyrine and nifedipine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antipyrine; Biotransformati | 1996 |
12 other studies available for antipyrine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Antipyrine kinetics in Nigerian women in chronic renal failure.
Topics: Adolescent; Adult; Antipyrine; Creatinine; Female; Humans; Kidney Failure, Chronic; Kinetics; Middle | 1982 |
Effect of renal failure and bis(2-ethylhexyl) phthalate pretreatment on the disposition and metabolism of antipyrine in the rat.
Topics: Animals; Antipyrine; Corn Oil; Creatinine; Diethylhexyl Phthalate; Hemeproteins; Kidney Failure, Chr | 1984 |
Assessment of total body water and lean body mass from anthropometry, Watson formula, creatinine kinetics, and body electrical impedance compared with antipyrine kinetics in peritoneal dialysis patients.
Topics: Adult; Anthropometry; Antipyrine; Biometry; Body Composition; Body Mass Index; Body Water; Creatinin | 1997 |
Determination of antipyrine and metabolites in plasma of a patient with mild renal failure.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Chromatography, High Pressure Liquid; Ed | 1997 |
Salivary antipyrine kinetics in hepatic and renal disease and in patients on anticonvulsant therapy.
Topics: Adult; Aged; Anticonvulsants; Antipyrine; Chronic Disease; Female; Half-Life; Humans; Kidney Failure | 1977 |
In vitro hepatic oxidative metabolism of antipyrine, phenytoin and phenylbutazone in rabbits with experimental renal failure.
Topics: Animals; Antipyrine; In Vitro Techniques; Kidney Failure, Chronic; Kinetics; Liver; Oxidation-Reduct | 1978 |
Drug distribution in renal failure.
Topics: Antipyrine; Clofibrate; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Kidney Failure, Ch | 1977 |
The plasma half-life of antipyrine in chromic uraemic and normal subjects.
Topics: Administration, Oral; Adolescent; Adult; Antipyrine; Enzyme Induction; Female; Half-Life; Humans; In | 1975 |
Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when coadministered with NSAID or antipyrine, propranolol or diazepam.
Topics: Adult; Aged; Aging; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Diazepam; Drug | 1990 |
Functional status of the liver during chronic renal failure: an experimental study in the rabbit.
Topics: Animals; Antipyrine; Body Weight; Edetic Acid; Galactose; Kidney Failure, Chronic; Liver; Male; Meta | 1985 |
Antipyrine metabolite formation and excretion in patients with chronic renal failure.
Topics: Adult; Aged; Antipyrine; Edaravone; Female; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Ma | 1985 |
Phenacetin and renal pelvic carcinoma.
Topics: Age Factors; Antipyrine; Caffeine; Female; Humans; Kidney Failure, Chronic; Kidney Neoplasms; Kidney | 1974 |