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antipyrine and Kidney Diseases

antipyrine has been researched along with Kidney Diseases in 20 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"A retrospective review was carried out of 207 Japanese patients with acute stroke who developed renal disorders on edaravone treatment."3.74Clinical analysis of 207 patients who developed renal disorders during or after treatment with edaravone reported during post-marketing surveillance. ( Hishida, A, 2007)
"Edaravone, 3-methyl-1-phenyl-pyrazolin-5-one, was administrated intravenously at a dose of 30 mg/kg of body weight to male Wistar rats (200-220 g)."3.72Edaravone inhibits acute renal injury and cyst formation in cisplatin-treated rat kidney. ( Chang, B; Iguchi, T; Inoue, M; Muroya, O; Nakatani, T; Nishikawa, M; Sato, EF, 2004)
"Oxcarbazepine (OCBZ) is a new antiepileptic drug (AED) structurally related to carbamazepine (CBZ) but differing in several important aspects, notably metabolism and induction of metabolic pathways."2.39Clinical pharmacology and pharmacokinetics of oxcarbazepine. ( Dieterle, W; Flesch, G; Lloyd, P, 1994)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199013 (65.00)18.7374
1990's2 (10.00)18.2507
2000's3 (15.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avdeef, A1
Tam, KY1
Oudart, JB1
Braham, ID1
Maquart, FX1
Satoh, M1
Kashihara, N1
Fujimoto, S1
Horike, H1
Tokura, T1
Namikoshi, T1
Sasaki, T1
Makino, H1
AXELSSON, U1
GILMAN, A1
Iguchi, T1
Nishikawa, M1
Chang, B1
Muroya, O1
Sato, EF1
Nakatani, T1
Inoue, M1
Hishida, A1
Henry, MA1
Sweet, RS1
Tange, JD1
Vanherweghem, JL1
Even-Adin, D1
NĂ©meth, I1
Szeleczki, T1
Lloyd, P1
Flesch, G1
Dieterle, W1
Sanders, TW1
Reinhard, MK1
Jollow, DJ1
Hottendorf, GH1
Bengtsson, U1
Dengler, HJ1
Eichelbaum, M1
Mihatsch, MJ1
Bengtsson, V1
Nanra, RS1
Kincaid-Smith, P1
Naess, K1
Prescott, LF1

Reviews

3 reviews available for antipyrine and Kidney Diseases

ArticleYear
Clinical pharmacology and pharmacokinetics of oxcarbazepine.
    Epilepsia, 1994, Volume: 35 Suppl 3

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Antipyrine; Carbamazepine; Child; Cytochrome

1994
Prevention of renal disease.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1979, Volume: 16

    Topics: Anti-Glomerular Basement Membrane Disease; Antipyrine; Caffeine; Chronic Disease; Female; Glomerulon

1979
Chronic effect of analgesics on the kidney.
    Progress in biochemical pharmacology, 1972, Volume: 7

    Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Aspirin; Caffeine; Chronic Disease; Drug Combinations;

1972

Other Studies

17 other studies available for antipyrine and Kidney Diseases

ArticleYear
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological

2010
Unexpected Creatinine Values.
    Clinical chemistry, 2016, Volume: 62, Issue:12

    Topics: Acute Coronary Syndrome; Adrenergic beta-1 Receptor Agonists; Aged, 80 and over; Antipyrine; Blood U

2016
A novel free radical scavenger, edarabone, protects against cisplatin-induced acute renal damage in vitro and in vivo.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:3

    Topics: Acute Disease; Animals; Antipyrine; Apoptosis; Cell Size; Cell Survival; Cisplatin; Edaravone; Free

2003
[Papillitis necroticans renalis & hemolytic anemia in a phenazone addict].
    Nordisk medicin, 1958, Jun-26, Volume: 59, Issue:26

    Topics: Aminopyrine; Anemia; Anemia, Hemolytic; Antipyrine; Kidney; Kidney Diseases; Papilledema

1958
ANALGESIC NEPHROTOXICITY; A PHARMACOLOGICAL ANALYSIS.
    The American journal of medicine, 1964, Volume: 36

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Aspirin; Kidney Diseases; Methemoglo

1964
Edaravone inhibits acute renal injury and cyst formation in cisplatin-treated rat kidney.
    Free radical research, 2004, Volume: 38, Issue:4

    Topics: Animals; Antineoplastic Agents; Antipyrine; Apoptosis; Body Weight; Cisplatin; DNA; DNA, Mitochondri

2004
Clinical analysis of 207 patients who developed renal disorders during or after treatment with edaravone reported during post-marketing surveillance.
    Clinical and experimental nephrology, 2007, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Antipyrine; Blood Urea Nitrogen; Creatinine; Edaravone; Female; Free Radica

2007
A new reproducible experimental model of analgesic nephropathy.
    The Journal of pathology, 1983, Volume: 139, Issue:1

    Topics: Acetaminophen; Analgesics; Animals; Antipyrine; Aspirin; Disease Models, Animal; Female; Kidney; Kid

1983
Epidemiology of analgesic nephropathy in Belgium.
    Clinical nephrology, 1982, Volume: 17, Issue:3

    Topics: Acetaminophen; Analgesics; Antipyrine; Aspirin; Belgium; Caffeine; Drug Combinations; Humans; Kidney

1982
Enhanced drug metabolism and renal dysfunction.
    British journal of clinical pharmacology, 1981, Volume: 11, Issue:1

    Topics: Antipyrine; Child; Glucaric Acid; Half-Life; Humans; Kidney Diseases; Pharmaceutical Preparations; S

1981
Lack of in vivo evidence of a cytochrome P450 metabolite participating in aminoglycoside nephrotoxicity.
    Biochemical pharmacology, 1993, Feb-09, Volume: 45, Issue:3

    Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Gentamicins; Kidney Diseases; Liver; Male; Prot

1993
[Polymorphisms and deficient drug metabolism as triggers of toxic reactions (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:96

    Topics: Animals; Antipyrine; Cyclacillin; Diazepam; Drug-Related Side Effects and Adverse Reactions; Humans;

1977
Does pyrazolone-induced renal injury exist?
    Agents and actions. Supplements, 1986, Volume: 19

    Topics: Acute Kidney Injury; Aged; Aminopyrine; Analgesics; Animals; Antipyrine; Cats; Dose-Response Relatio

1986
Editorial: Drug metabolism in disease.
    Lancet (London, England), 1974, Apr-27, Volume: 1, Issue:7861

    Topics: Alanine Transaminase; Anti-Bacterial Agents; Antipyrine; Half-Life; Humans; Kidney; Kidney Diseases;

1974
Phenacetin.
    Lancet (London, England), 1969, Feb-01, Volume: 1, Issue:7588

    Topics: Acetaminophen; Antipyrine; Denmark; Humans; Kidney Diseases; Kidney Neoplasms; Kidney Papillary Necr

1969
[Risks in long-term treatment with analgesics].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Mar-30, Volume: 93, Issue:9

    Topics: Acetaminophen; Analgesics; Antipyrine; Aspirin; Caffeine; Diuresis; Drug Combinations; Humans; Kidne

1973
Phenacetin nephropathy.
    British medical journal, 1970, Nov-21, Volume: 4, Issue:5733

    Topics: Animals; Antipyrine; Humans; Kidney Diseases; Kidney Papillary Necrosis; Phenacetin; Salicylates

1970