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antipyrine and Ischemic Attack, Transient

antipyrine has been researched along with Ischemic Attack, Transient in 42 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"To describe a patient who developed reversible segmental cerebral arterial vasospasm and cerebral infarction while taking excessive amounts of sumatriptan succinate and a combination drug (Midrin) consisting of isometheptene mucate, 65 mg, dichloralphenazone, 100 mg, and acetaminophen, 325 mg."8.80Reversible segmental cerebral arterial vasospasm and cerebral infarction: possible association with excessive use of sumatriptan and Midrin. ( Biller, J; Malkoff, MD; Meschia, JF, 1998)
"To describe a patient who developed reversible segmental cerebral arterial vasospasm and cerebral infarction while taking excessive amounts of sumatriptan succinate and a combination drug (Midrin) consisting of isometheptene mucate, 65 mg, dichloralphenazone, 100 mg, and acetaminophen, 325 mg."4.80Reversible segmental cerebral arterial vasospasm and cerebral infarction: possible association with excessive use of sumatriptan and Midrin. ( Biller, J; Malkoff, MD; Meschia, JF, 1998)
"A previous study indicated that diaspirin-crosslinked hemoglobin (DCLHb) decreases cerebral ischemia after subarachnoid hemorrhage."3.70Subarachnoid molecular hemoglobin after subarachnoid hemorrhage in rats: effect on the area of hypoperfusion. ( Cole, DJ; Cross, LM; Drummond, JC; McKay, LD; Patel, PM, 1998)
"Edaravone was treated twice via tail vein; after MCA occlusion and after reperfusion."1.43A free radical scavenger edaravone suppresses systemic inflammatory responses in a rat transient focal ischemia model. ( Arai, K; Fujiwara, N; Lee, BJ; Lo, EH; Mandeville, ET; Pham, LD; Som, AT, 2016)
"Treatment with edaravone significantly increased the number of NSPCs and newly generated neurons in the subgranular zone (p < ."1.40Pre- and posttreatment with edaravone protects CA1 hippocampus and enhances neurogenesis in the subgranular zone of dentate gyrus after transient global cerebral ischemia in rats. ( Chen, X; Gao, M; He, X; Lei, S; Li, W; Li, X; Liu, Y; Lu, H; Qi, C; Wang, N; Wang, X; Zhang, J; Zhang, P; Zheng, J, 2014)
"Edaravone treatment significantly inhibited both lipid and DNA oxidative damage 72h after ischemia, and decreased neuronal damage."1.38Edaravone, a free radical scavenger, attenuates behavioral deficits following transient forebrain ischemia by inhibiting oxidative damage in gerbils. ( Hirooka, K; Itano, T; Kawai, N; Keep, RF; Liu, Y; Lu, F; Miyamoto, O; Nakamura, T; Okabe, N; Shiraga, F; Tamiya, T; Toyoshima, T, 2012)
"A 68-year-old man with left cervical internal carotid artery stenosis suffered crescendo transient ischemic attacks caused by mobile thrombus detected by carotid echography and secondary impairment of cerebral hemodynamic reserve demonstrated by positron emission tomography."1.34Urgent endarterectomy using pretreatment with free radical scavenger, edaravone, and early clamping of the parent arteries for cervical carotid artery stenosis with crescendo transient ischemic attacks caused by mobile thrombus and hemodynamic cerebral is ( Inoue, T; Kobayashi, M; Komoribayashi, N; Ogasawara, K; Ogawa, A; Saito, H; Suga, Y, 2007)
"Pretreatment with edaravone but not post-treatment dose-dependently improved the response to high K+ but not the massive dopamine increase during ischemia."1.34Improvement of postischemic dopaminergic dysfunction by edaravone, a free radical scavenger. ( Akiyama, Y; Miwa, S, 2007)
"The volume of cerebral infarction, induced by 2-h occlusion and subsequent 2-h reperfusion of MCA in Fisher-344 rats, was evaluated."1.30Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat. ( Iwai, T; Nakashima, M; Niwa, M; Uematsu, T, 1999)
"Pretreatment with mannitol prevented postischemic obstruction of the microcirculation during 5 minutes of recirculation after 30 minutes of severe temporary ischemia, but the EEG signals did not recover."1.28Effect of mannitol on local cerebral blood flow after temporary complete cerebral ischemia in rats. ( Shirane, R; Weinstein, PR, 1992)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199013 (30.95)18.7374
1990's15 (35.71)18.2507
2000's8 (19.05)29.6817
2010's6 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lei, S1
Zhang, P1
Li, W1
Gao, M1
He, X1
Zheng, J1
Li, X1
Wang, X1
Wang, N1
Zhang, J1
Qi, C1
Lu, H1
Chen, X1
Liu, Y2
Fujiwara, N1
Som, AT1
Pham, LD1
Lee, BJ1
Mandeville, ET1
Lo, EH1
Arai, K1
Liu, N1
Shang, J1
Tian, F1
Nishi, H1
Abe, K1
Yamamoto, Y1
Ohara, T1
Nagakane, Y1
Tanaka, E1
Morii, F1
Koizumi, T1
Lu, F1
Nakamura, T1
Toyoshima, T1
Hirooka, K1
Kawai, N1
Okabe, N1
Shiraga, F1
Tamiya, T1
Miyamoto, O1
Keep, RF1
Itano, T1
Ahmad, A1
Khan, MM1
Javed, H1
Raza, SS1
Ishrat, T1
Khan, MB1
Safhi, MM1
Islam, F1
Murphy, SJ1
Littleton-Kearney, MT1
Hurn, PD3
Kobayashi, M1
Ogasawara, K1
Inoue, T1
Saito, H1
Komoribayashi, N1
Suga, Y1
Ogawa, A1
Akiyama, Y1
Miwa, S1
Xiao, B1
Bi, FF1
Hu, YQ1
Tian, FF1
Wu, ZG1
Mujlli, HM1
Ding, L1
Zhou, XF1
Wei, HM1
Chi, OZ1
Liu, X1
Sinha, AK1
Weiss, HR1
Takagi, K1
Zhao, W1
Busto, R1
Ginsberg, MD1
Gartshore, G1
Dawson, D1
Patterson, J1
Macrae, IM2
Nozaki, H3
Tanaka, K6
Gomi, S2
Mihara, B2
Nogawa, S4
Nagata, E4
Kondo, T2
Fukuuchi, Y5
Tohyama, Y1
Sako, K2
Yonemasu, Y1
Dembo, T3
Tsuchidate, R1
He, QP1
Smith, ML1
Siesjö, BK1
Alkayed, NJ2
Harukuni, I1
Kimes, AS1
London, ED1
Traystman, RJ1
Meschia, JF1
Malkoff, MD1
Biller, J1
Watanabe, H1
Kumon, Y1
Ohta, S1
Sakaki, S1
Matsuda, S1
Sakanaka, M1
Cole, DJ1
McKay, LD1
Drummond, JC1
Patel, PM1
Cross, LM1
Nakashima, M1
Niwa, M1
Iwai, T1
Uematsu, T1
Suzuki, S2
Kosakai, A2
MacGregor, DG1
Carswell, HV1
Graham, DI1
McCulloch, J1
Vannucci, SJ1
Willing, LB1
Goto, S1
Brucklacher, RM1
Wood, TL1
Towfighi, J1
Simpson, IA1
Ito, D1
Kimura, T1
Kusakabe, M1
Tanaka, T1
Nakada, T1
Takashima, S1
Shirai, T1
Shirane, R1
Weinstein, PR1
Kataoka, K1
Hayakawa, T2
Graf, R1
Yamada, K2
Kuroda, R1
Abekura, M1
Mogami, H2
Heiss, WD1
Selman, WR1
VanDerVeer, C1
Whittingham, TS1
LaManna, JC1
Lust, WD1
Ratcheson, RA1
Jacewicz, M1
Kiessling, M1
Pulsinelli, WA1
Yoshimine, T1
Takemoto, O1
Kato, A1
Ushio, Y1
Tobita, M1
Nagasawa, H1
Kogure, K1
Sato, H1
Yoshioka, S1
Matsuzawa, T1
Delgado, TJ2
Arbab, MA1
Diemer, NH2
Svendgaard, NA2
Dinsdale, HB1
Robertson, DM1
Haas, RA1
O'Brien, MD1
Jordan, MM1
Waltz, AG5
Blair, RD2
Yamaguchi, T2
Regli, F1
Okazaki, H1

Reviews

2 reviews available for antipyrine and Ischemic Attack, Transient

ArticleYear
[Concept of branch atheromatous disease (BAD) and its clinical significance].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:11

    Topics: Antipyrine; Arginine; Cerebral Infarction; Cilostazol; Drug Therapy, Combination; Edaravone; Humans;

2010
Reversible segmental cerebral arterial vasospasm and cerebral infarction: possible association with excessive use of sumatriptan and Midrin.
    Archives of neurology, 1998, Volume: 55, Issue:5

    Topics: Acetaminophen; Adult; Antipyrine; Cerebral Infarction; Chloral Hydrate; Drug Combinations; Drug Ther

1998

Other Studies

40 other studies available for antipyrine and Ischemic Attack, Transient

ArticleYear
Pre- and posttreatment with edaravone protects CA1 hippocampus and enhances neurogenesis in the subgranular zone of dentate gyrus after transient global cerebral ischemia in rats.
    ASN neuro, 2014, Volume: 6, Issue:6

    Topics: Animals; Animals, Newborn; Antipyrine; Apoptosis; CA1 Region, Hippocampal; Cell Death; Cells, Cultur

2014
A free radical scavenger edaravone suppresses systemic inflammatory responses in a rat transient focal ischemia model.
    Neuroscience letters, 2016, 10-28, Volume: 633

    Topics: Animals; Antipyrine; Brain Edema; Cerebral Infarction; Cytokines; Edaravone; Free Radical Scavengers

2016
In vivo optical imaging for evaluating the efficacy of edaravone after transient cerebral ischemia in mice.
    Brain research, 2011, Jun-23, Volume: 1397

    Topics: Animals; Annexin A5; Antipyrine; Apoptosis; Autophagy; Blood-Brain Barrier; Blotting, Western; Cereb

2011
Edaravone, a free radical scavenger, attenuates behavioral deficits following transient forebrain ischemia by inhibiting oxidative damage in gerbils.
    Neuroscience letters, 2012, Jan-06, Volume: 506, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Antipyrine; Behavioral Symptoms; Deoxygu

2012
Edaravone ameliorates oxidative stress associated cholinergic dysfunction and limits apoptotic response following focal cerebral ischemia in rat.
    Molecular and cellular biochemistry, 2012, Volume: 367, Issue:1-2

    Topics: Animals; Antipyrine; Apoptosis; Basal Ganglia; Caspase 3; Choline O-Acetyltransferase; Cholinergic N

2012
Progesterone administration during reperfusion, but not preischemia alone, reduces injury in ovariectomized rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2002, Volume: 22, Issue:10

    Topics: Animals; Antipyrine; Autoradiography; Blood Flow Velocity; Blood Pressure; Carbon Radioisotopes; Cer

2002
Urgent endarterectomy using pretreatment with free radical scavenger, edaravone, and early clamping of the parent arteries for cervical carotid artery stenosis with crescendo transient ischemic attacks caused by mobile thrombus and hemodynamic cerebral is
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:3

    Topics: Aged; Antipyrine; Carotid Stenosis; Edaravone; Endarterectomy, Carotid; Free Radical Scavengers; Hum

2007
Improvement of postischemic dopaminergic dysfunction by edaravone, a free radical scavenger.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:1

    Topics: Animals; Antipyrine; Corpus Striatum; Dialysis Solutions; Dopamine; Dose-Response Relationship, Drug

2007
Edaravone neuroprotection effected by suppressing the gene expression of the Fas signal pathway following transient focal ischemia in rats.
    Neurotoxicity research, 2007, Volume: 12, Issue:3

    Topics: Animals; Antipyrine; Death Domain Receptor Signaling Adaptor Proteins; Disease Models, Animal; DNA F

2007
Nitric oxide synthase inhibition alters cerebral blood flow and oxygen balance in focal cerebral ischemia in rats.
    Stroke, 1994, Volume: 25, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Antipyrine; Arginine; Brain; Carbon Radioisotopes; Cerebral Art

1994
Local hemodynamic changes during transient middle cerebral artery occlusion and recirculation in the rat: a [14C]iodoantipyrine autoradiographic study.
    Brain research, 1995, Sep-11, Volume: 691, Issue:1-2

    Topics: Acute Disease; Analysis of Variance; Animals; Antipyrine; Arterial Occlusive Diseases; Autoradiograp

1995
Topographic profile of reperfusion into MCA territory following endothelin-1-induced transient focal cerebral ischaemia.
    Neuroscience letters, 1996, Jan-05, Volume: 202, Issue:3

    Topics: Animals; Antipyrine; Autoradiography; Cerebral Arteries; Cerebrovascular Circulation; Collateral Cir

1996
Alteration of ryanodine receptor in the hippocampus CA1 after hemispheric cerebral ischemia.
    Neurochemical research, 1996, Volume: 21, Issue:8

    Topics: Animals; Antipyrine; Autoradiography; Brain; Calcium; Calcium Channels; Carbon Radioisotopes; Gerbil

1996
Protein kinase C in focal ischemic rat brain: dual autoradiographic analysis of [14C]iodoantipyrine (IAP) and [3H]phorbol-12,13-dibutyrate (PDBu).
    Brain research, 1997, Mar-07, Volume: 750, Issue:1-2

    Topics: Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Carotid Artery, Common; Cerebral

1997
Acute ischemic vulnerability of PKA in the dendritic subfields of the hippocampus CA1.
    Neuroreport, 1997, Jul-28, Volume: 8, Issue:11

    Topics: Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cerebrovascular Circulation; Cyclic AMP;

1997
Regional cerebral blood flow during and after 2 hours of middle cerebral artery occlusion in the rat.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:10

    Topics: Animals; Antipyrine; Autoradiography; Cerebral Arteries; Cerebrovascular Circulation; Constriction;

1997
Gender-linked brain injury in experimental stroke.
    Stroke, 1998, Volume: 29, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoradiography; Brain; Carbon Radiois

1998
Changes in protein synthesis and calcium homeostasis in the thalamus of spontaneously hypertensive rats with focal cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1998, Volume: 18, Issue:6

    Topics: Animals; Antipyrine; Autoradiography; Calcium; Calcium Radioisotopes; Homeostasis; Hypertension; Isc

1998
Subarachnoid molecular hemoglobin after subarachnoid hemorrhage in rats: effect on the area of hypoperfusion.
    Journal of neurosurgical anesthesiology, 1998, Volume: 10, Issue:3

    Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Antipyrine; Aspirin; Blood; Blood Substitute

1998
Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat.
    Free radical biology & medicine, 1999, Volume: 26, Issue:5-6

    Topics: Animals; Antipyrine; Brain; Caudate Nucleus; Cerebral Infarction; Cyclic N-Oxides; Disease Models, A

1999
Inhibition of cyclic AMP-dependent protein kinase in the acute phase of focal cerebral ischemia in the rat.
    Neuroscience, 1999, Volume: 94, Issue:2

    Topics: Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Caudate Nucleus; Cerebral Cortex;

1999
Impaired cerebral autoregulation 24 h after induction of transient unilateral focal ischaemia in the rat.
    The European journal of neuroscience, 2000, Volume: 12, Issue:1

    Topics: Animals; Antipyrine; Blood Pressure; Brain; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Cereb

2000
Experimental stroke in the female diabetic, db/db, mouse.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2001, Volume: 21, Issue:1

    Topics: Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Cerebral Infarction; Cerebrovascu

2001
Phosphorylation of cyclic adenosine monophosphate response element binding protein in oligodendrocytes in the corpus callosum after focal cerebral ischemia in the rat.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2001, Volume: 21, Issue:10

    Topics: Adenomatous Polyposis Coli Protein; Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cere

2001
Effect of mild hypothermia on energy state recovery following transient forebrain ischemia in the gerbil.
    Experimental brain research, 2002, Volume: 145, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antipyrine; Astrocytes; Body Temperature; Cerebral Cortex; Cerebral

2002
Alteration of second-messenger ligand binding following 2-hr hemispheric ischemia in the gerbil brain.
    Experimental neurology, 1992, Volume: 117, Issue:3

    Topics: Adenylyl Cyclases; Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Carotid Artery

1992
Effect of mannitol on local cerebral blood flow after temporary complete cerebral ischemia in rats.
    Journal of neurosurgery, 1992, Volume: 76, Issue:3

    Topics: Animals; Antipyrine; Autoradiography; Blood Gas Analysis; Blood Pressure; Carbon Radioisotopes; Cere

1992
[Neurofunctional disturbances as related to cortical ischemia and white matter ischemia].
    No to shinkei = Brain and nerve, 1989, Volume: 41, Issue:2

    Topics: Animals; Antipyrine; Auditory Cortex; Autoradiography; Brain Ischemia; Carbon Radioisotopes; Cats; C

1989
Visually defined zones of focal ischemia in the rat brain.
    Neurosurgery, 1987, Volume: 21, Issue:6

    Topics: Adenosine Triphosphate; Animals; Antipyrine; Autoradiography; Brain; Glucose; Ischemic Attack, Trans

1987
Selective gene expression in focal cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:3

    Topics: Animals; Antipyrine; Autoradiography; Blood Flow Velocity; Cerebral Cortex; Cerebrovascular Circulat

1986
Regional cerebral ischemia in the gerbil: measurement of regional cerebral blood flow by quantitative autoradiography.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:3

    Topics: Animals; Antipyrine; Autoradiography; Blood Flow Velocity; Carotid Arteries; Cerebral Arteries; Cere

1986
Sequential cerebral blood flow study by chrono-autoradiography.
    The Tohoku journal of experimental medicine, 1986, Volume: 149, Issue:1

    Topics: Amphetamines; Animals; Antipyrine; Autoradiography; Cerebrovascular Circulation; Iofetamine; Ischemi

1986
Subarachnoid hemorrhage in the rat: cerebral blood flow and glucose metabolism during the late phase of cerebral vasospasm.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:5

    Topics: Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Deox

1986
Subarachnoid hemorrhage in the rat: cerebral blood flow and glucose metabolism after selective lesions of the catecholamine systems in the brainstem.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:5

    Topics: Animals; Antipyrine; Autoradiography; Brain; Brain Stem; Carbon Radioisotopes; Catecholamines; Cereb

1986
Acute hypertension and prolonged focal cerebral ischemia.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Angiotensin II; Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cerebrovascular Circulat

1973
Ischemic cerebral edema and the blood-brain barrier. Distributions of pertechnetate, albumin, sodium, and antipyrine in brains of cats after occlusion of the middle cerebral artery.
    Archives of neurology, 1974, Volume: 30, Issue:6

    Topics: Albumins; Animals; Antipyrine; Blood-Brain Barrier; Brain; Brain Edema; Cats; Cerebrovascular Disord

1974
Correlation of changes in superficial microcirculation with regional blood flow during acute cerebral ischemia.
    Neurology, 1968, Volume: 18, Issue:3

    Topics: Animals; Antipyrine; Autoradiography; Carbon Isotopes; Cerebral Cortex; Cerebrovascular Circulation;

1968
Regional cerebral blood flow during acute ischemia. Correlation of autoradiographic measurements with observations of cortical microcirculation.
    Neurology, 1970, Volume: 20, Issue:8

    Topics: Acute Disease; Animals; Antipyrine; Autoradiography; Carbon Isotopes; Cerebral Arteries; Cerebral Co

1970
Effects of hyperventilation with and without carbon dioxide on experimental cerebral ischaemia and infarction. Studies of regional cerebral blood flow and histopathology after occlusion of a middle cerebral artery in cats.
    Brain : a journal of neurology, 1972, Volume: 95, Issue:1

    Topics: Animals; Antipyrine; Autoradiography; Brain; Brain Edema; Carbon Dioxide; Carbon Isotopes; Cats; Cer

1972
Hyperemia and ischemia in experimental cerebral infarction: correlation of histopathology and regional blood flow.
    Neurology, 1971, Volume: 21, Issue:6

    Topics: Animals; Antipyrine; Autoradiography; Blood Flow Velocity; Carbon Isotopes; Cats; Caudate Nucleus; C

1971