Page last updated: 2024-10-22

antipyrine and Injuries, Radiation

antipyrine has been researched along with Injuries, Radiation in 5 studies

Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.

Research Excerpts

ExcerptRelevanceReference
" This study was designed to evaluate the protective effect of edaravone, a free radical scavenger, on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma."9.19Effect of edaravone on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma after radiotherapy: a randomized controlled trial. ( Hu, W; Li, G; Luo, J; Rong, X; Tang, Y; Xu, P; Yang, J; Yang, X, 2014)
" This study was designed to evaluate the protective effect of edaravone, a free radical scavenger, on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma."5.19Effect of edaravone on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma after radiotherapy: a randomized controlled trial. ( Hu, W; Li, G; Luo, J; Rong, X; Tang, Y; Xu, P; Yang, J; Yang, X, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, C1
Bryant, A1
Brown, PD1
Tang, Y1
Rong, X1
Hu, W1
Li, G1
Yang, X1
Yang, J1
Xu, P1
Luo, J1
TERZANI, A1
Anzai, K1
Furuse, M1
Yoshida, A1
Matsuyama, A1
Moritake, T1
Tsuboi, K1
Ikota, N1
Ishii, J1
Natsume, A1
Wakabayashi, T1
Takeuchi, H1
Hasegawa, H1
Kim, SU1
Yoshida, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Edaravone on Radiation-induced Temporal Lobe Necrosis in Patients With Nasopharyngeal Carcinoma After Radiotherapy[NCT01865201]Phase 2154 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for antipyrine and Injuries, Radiation

ArticleYear
Interventions for the treatment of brain radionecrosis after radiotherapy or radiosurgery.
    The Cochrane database of systematic reviews, 2018, 07-09, Volume: 7

    Topics: Adrenal Cortex Hormones; Adult; Antipyrine; Bevacizumab; Brain; Brain Edema; Drug Therapy, Combinati

2018

Trials

1 trial available for antipyrine and Injuries, Radiation

ArticleYear
Effect of edaravone on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma after radiotherapy: a randomized controlled trial.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antipyrine; Brain Injuries; Carcinoma; Case-Control Studies; Edaravo

2014

Other Studies

3 other studies available for antipyrine and Injuries, Radiation

ArticleYear
[DAMAGE FROM THERAPY].
    La Clinica terapeutica, 1963, Oct-15, Volume: 27

    Topics: Adrenal Cortex Hormones; Anemia; Anemia, Aplastic; Anticoagulants; Antipyrine; Blood Group Incompati

1963
In vivo radioprotection of mice by 3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone; Radicut), a clinical drug.
    Journal of radiation research, 2004, Volume: 45, Issue:2

    Topics: Animals; Antipyrine; Body Temperature; Dose-Response Relationship, Drug; Dose-Response Relationship,

2004
The free-radical scavenger edaravone restores the differentiation of human neural precursor cells after radiation-induced oxidative stress.
    Neuroscience letters, 2007, Aug-23, Volume: 423, Issue:3

    Topics: Animals; Antipyrine; Brain Neoplasms; Cell Differentiation; Cells, Cultured; Edaravone; Free Radical

2007